Cross-version Extension for R4B.Ingredient for use in FHIR R4 - Definitions - FHIR Cross-Version Extensions package for FHIR R4 from FHIR R4B v0.0.1-snapshot-2

FHIR Cross-Version Extensions package for FHIR R4 from FHIR R4B - Version 0.0.1-snapshot-2. See the Directory of published versions

Extension: Ext_R4B_Ingredient - Detailed Descriptions

Page standards status: Informative

Maturity Level: 0

Definitions for the ext-R4B-Ingredient extension.

Differential Elements Table
Key Elements Table
Snapshot Elements Table

Guidance on how to interpret the contents of this table can be foundhere

0. Extension
Definition	This cross-version extension represents Ingredient from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	An ingredient of a manufactured item or pharmaceutical product
Control	0..*
2. Extension.extension
Control	3..*
Slicing	This element introduces a set of slices on `Extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
4. Extension.extension:status
Slice Name	status
Definition	The status of this ingredient. Enables tracking the life-cycle of the content.
Short	draft \| active \| retired \| unknown
Control	1..1
6. Extension.extension:status.url
Control	1..1
Fixed Value	`status`
8. Extension.extension:status.value[x]
Definition	The status of this ingredient. Enables tracking the life-cycle of the content.
Short	draft \| active \| retired \| unknown
Binding	The codes SHALL be taken from PublicationStatus (required to `http://hl7.org/fhir/ValueSet/publication-status\|4.0.1`) The lifecycle status of an artifact.
Type	code
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
10. Extension.extension:for
Slice Name	for
Definition	This cross-version extension represents Ingredient.for from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The product which this ingredient is a constituent part of
Control	0..*
12. Extension.extension:for.url
Control	1..1
Fixed Value	`for`
14. Extension.extension:for.value[x]
Definition	This cross-version extension represents Ingredient.for from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The product which this ingredient is a constituent part of
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
16. Extension.extension:role
Slice Name	role
Definition	A classification of the ingredient identifying its purpose within the product, e.g. active, inactive.
Short	Purpose of the ingredient within the product, e.g. active, inactive
Control	1..1
18. Extension.extension:role.url
Control	1..1
Fixed Value	`role`
20. Extension.extension:role.value[x]
Definition	A classification of the ingredient identifying its purpose within the product, e.g. active, inactive.
Short	Purpose of the ingredient within the product, e.g. active, inactive
Binding	For example codes, see R4B_ingredient_role_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-ingredient-role-for-R4\|0.0.1-snapshot-2`) A classification of the ingredient identifying its purpose within the product, e.g. active, inactive.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
22. Extension.extension:function
Slice Name	function
Definition	A classification of the ingredient identifying its precise purpose(s) in the drug product. This extends the Ingredient.role to add more detail. Example: antioxidant, alkalizing agent.
Short	Precise action within the drug product, e.g. antioxidant, alkalizing agent
Control	0..*
24. Extension.extension:function.url
Control	1..1
Fixed Value	`function`
26. Extension.extension:function.value[x]
Definition	A classification of the ingredient identifying its precise purpose(s) in the drug product. This extends the Ingredient.role to add more detail. Example: antioxidant, alkalizing agent.
Short	Precise action within the drug product, e.g. antioxidant, alkalizing agent
Binding	For example codes, see R4B_ingredient_function_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-ingredient-function-for-R4\|0.0.1-snapshot-2`) A classification of the ingredient identifying its precise purpose(s) in the drug product (beyond e.g. active/inactive).
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
28. Extension.extension:allergenicIndicator
Slice Name	allergenicIndicator
Definition	If the ingredient is a known or suspected allergen. Note that this is a property of the substance, so if a reference to a SubstanceDefinition is used to decribe that (rather than just a code), the allergen information should go there, not here.
Short	If the ingredient is a known or suspected allergen
Control	0..1
30. Extension.extension:allergenicIndicator.url
Control	1..1
Fixed Value	`allergenicIndicator`
32. Extension.extension:allergenicIndicator.value[x]
Definition	If the ingredient is a known or suspected allergen. Note that this is a property of the substance, so if a reference to a SubstanceDefinition is used to decribe that (rather than just a code), the allergen information should go there, not here.
Short	If the ingredient is a known or suspected allergen
Type	boolean
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
34. Extension.extension:manufacturer
Slice Name	manufacturer
Definition	The organization(s) that manufacture this ingredient. Can be used to indicate: 1) Organizations we are aware of that manufacture this ingredient 2) Specific Manufacturer(s) currently being used 3) Set of organisations allowed to manufacture this ingredient for this product Users must be clear on the application of context relevant to their use case.
Short	An organization that manufactures this ingredient
Control	0..*
36. Extension.extension:manufacturer.extension
Control	1..*
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
38. Extension.extension:manufacturer.extension:role
Slice Name	role
Definition	The way in which this manufacturer is associated with the ingredient. For example whether it is a possible one (others allowed), or an exclusive authorized one for this ingredient. Note that this is not the manufacturing process role.
Short	allowed \| possible \| actual
Control	0..1
40. Extension.extension:manufacturer.extension:role.url
Control	1..1
Fixed Value	`role`
42. Extension.extension:manufacturer.extension:role.value[x]
Definition	The way in which this manufacturer is associated with the ingredient. For example whether it is a possible one (others allowed), or an exclusive authorized one for this ingredient. Note that this is not the manufacturing process role.
Short	allowed \| possible \| actual
Binding	The codes SHALL be taken from R4B_ingredient_manufacturer_role_for_R4 (0.0.1-snapshot-2) (required to `http://hl7.org/fhir/4.3/ValueSet/R4B-ingredient-manufacturer-role-for-R4\|0.0.1-snapshot-2`) The way in which this manufacturer is associated with the ingredient.
Type	code
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
44. Extension.extension:manufacturer.extension:manufacturer
Slice Name	manufacturer
Definition	This cross-version extension represents Ingredient.manufacturer.manufacturer from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	An organization that manufactures this ingredient
Control	1..1
46. Extension.extension:manufacturer.extension:manufacturer.url
Control	1..1
Fixed Value	`manufacturer`
48. Extension.extension:manufacturer.extension:manufacturer.value[x]
Definition	This cross-version extension represents Ingredient.manufacturer.manufacturer from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	An organization that manufactures this ingredient
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
50. Extension.extension:manufacturer.url
Control	1..1
Fixed Value	`manufacturer`
52. Extension.extension:substance
Slice Name	substance
Definition	This cross-version extension represents Ingredient.substance from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The substance that comprises this ingredient
Control	1..1
54. Extension.extension:substance.extension
Control	1..*
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
56. Extension.extension:substance.extension:code
Slice Name	code
Definition	A code or full resource that represents the ingredient's substance.
Short	A code or full resource that represents the ingredient substance
Control	1..1
58. Extension.extension:substance.extension:code.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
60. Extension.extension:substance.extension:code.extension:concept
Slice Name	concept
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.
Short	Reference to a concept (by class)
Control	0..1
62. Extension.extension:substance.extension:code.extension:concept.url
Control	1..1
Fixed Value	`concept`
64. Extension.extension:substance.extension:code.extension:concept.value[x]
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.
Short	Reference to a concept (by class)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
66. Extension.extension:substance.extension:code.extension:reference
Slice Name	reference
Definition	A reference to a resource the provides exact details about the information being referenced.
Short	Reference to a resource (by instance)
Control	0..1
68. Extension.extension:substance.extension:code.extension:reference.url
Control	1..1
Fixed Value	`reference`
70. Extension.extension:substance.extension:code.extension:reference.value[x]
Definition	A reference to a resource the provides exact details about the information being referenced.
Short	Reference to a resource (by instance)
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
72. Extension.extension:substance.extension:code.extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.code from FHIR R4B
Short	Data type name for Ingredient.substance.code from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
74. Extension.extension:substance.extension:code.extension:_datatype.value[x]
Comments	Must be: CodeableReference
Control	1..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Fixed Value	`CodeableReference`
76. Extension.extension:substance.extension:code.url
Control	1..1
Fixed Value	`code`
78. Extension.extension:substance.extension:strength
Slice Name	strength
Definition	The quantity of substance in the unit of presentation, or in the volume (or mass) of the single pharmaceutical product or manufactured item. The allowed repetitions do not represent different strengths, but are different representations - mathematically equivalent - of a single strength.
Short	The quantity of substance, per presentation, or per volume or mass, and type of quantity
Control	0..*
80. Extension.extension:substance.extension:strength.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
82. Extension.extension:substance.extension:strength.extension:presentation[x]
Slice Name	presentation[x]
Definition	The quantity of substance in the unit of presentation, or in the volume (or mass) of the single pharmaceutical product or manufactured item. Unit of presentation refers to the quantity that the item occurs in e.g. a strength per tablet size, perhaps 'per 20mg' (the size of the tablet). It is not generally normalized as a unitary unit, which would be 'per mg').
Short	The quantity of substance in the unit of presentation
Control	0..1
84. Extension.extension:substance.extension:strength.extension:presentation[x].extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
86. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator
Slice Name	lowNumerator
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Control	0..1
88. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator.url
Control	1..1
Fixed Value	`lowNumerator`
90. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator.value[x]
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
92. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator
Slice Name	highNumerator
Definition	The value of the high limit numerator.
Short	High Numerator limit
Control	0..1
94. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator.url
Control	1..1
Fixed Value	`highNumerator`
96. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator.value[x]
Definition	The value of the high limit numerator.
Short	High Numerator limit
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
98. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator
Slice Name	denominator
Definition	The value of the denominator.
Short	Denominator value
Control	0..1
100. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator.url
Control	1..1
Fixed Value	`denominator`
102. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator.value[x]
Definition	The value of the denominator.
Short	Denominator value
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
104. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.presentation[x] from FHIR R4B
Short	Data type name for Ingredient.substance.strength.presentation[x] from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
106. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype.value[x]
Comments	Must be: RatioRange
Control	1..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Fixed Value	`RatioRange`
108. Extension.extension:substance.extension:strength.extension:presentation[x].url
Control	1..1
Fixed Value	`presentation[x]`
110. Extension.extension:substance.extension:strength.extension:presentation[x].value[x]
Definition	The quantity of substance in the unit of presentation, or in the volume (or mass) of the single pharmaceutical product or manufactured item. Unit of presentation refers to the quantity that the item occurs in e.g. a strength per tablet size, perhaps 'per 20mg' (the size of the tablet). It is not generally normalized as a unitary unit, which would be 'per mg').
Short	The quantity of substance in the unit of presentation
Type	Ratio
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
112. Extension.extension:substance.extension:strength.extension:textPresentation
Slice Name	textPresentation
Definition	A textual represention of either the whole of the presentation strength or a part of it - with the rest being in Strength.presentation as a ratio.
Short	Text of either the whole presentation strength or a part of it (rest being in Strength.presentation as a ratio)
Control	0..1
114. Extension.extension:substance.extension:strength.extension:textPresentation.url
Control	1..1
Fixed Value	`textPresentation`
116. Extension.extension:substance.extension:strength.extension:textPresentation.value[x]
Definition	A textual represention of either the whole of the presentation strength or a part of it - with the rest being in Strength.presentation as a ratio.
Short	Text of either the whole presentation strength or a part of it (rest being in Strength.presentation as a ratio)
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
118. Extension.extension:substance.extension:strength.extension:concentration[x]
Slice Name	concentration[x]
Definition	This cross-version extension represents Ingredient.substance.strength.concentration[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The strength per unitary volume (or mass)
Control	0..1
120. Extension.extension:substance.extension:strength.extension:concentration[x].extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
122. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator
Slice Name	lowNumerator
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Control	0..1
124. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator.url
Control	1..1
Fixed Value	`lowNumerator`
126. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator.value[x]
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
128. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator
Slice Name	highNumerator
Definition	The value of the high limit numerator.
Short	High Numerator limit
Control	0..1
130. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator.url
Control	1..1
Fixed Value	`highNumerator`
132. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator.value[x]
Definition	The value of the high limit numerator.
Short	High Numerator limit
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
134. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator
Slice Name	denominator
Definition	The value of the denominator.
Short	Denominator value
Control	0..1
136. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator.url
Control	1..1
Fixed Value	`denominator`
138. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator.value[x]
Definition	The value of the denominator.
Short	Denominator value
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
140. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.concentration[x] from FHIR R4B
Short	Data type name for Ingredient.substance.strength.concentration[x] from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
142. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype.value[x]
Comments	Must be: RatioRange
Control	1..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Fixed Value	`RatioRange`
144. Extension.extension:substance.extension:strength.extension:concentration[x].url
Control	1..1
Fixed Value	`concentration[x]`
146. Extension.extension:substance.extension:strength.extension:concentration[x].value[x]
Definition	This cross-version extension represents Ingredient.substance.strength.concentration[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The strength per unitary volume (or mass)
Type	Ratio
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
148. Extension.extension:substance.extension:strength.extension:textConcentration
Slice Name	textConcentration
Definition	A textual represention of either the whole of the concentration strength or a part of it - with the rest being in Strength.concentration as a ratio.
Short	Text of either the whole concentration strength or a part of it (rest being in Strength.concentration as a ratio)
Control	0..1
150. Extension.extension:substance.extension:strength.extension:textConcentration.url
Control	1..1
Fixed Value	`textConcentration`
152. Extension.extension:substance.extension:strength.extension:textConcentration.value[x]
Definition	A textual represention of either the whole of the concentration strength or a part of it - with the rest being in Strength.concentration as a ratio.
Short	Text of either the whole concentration strength or a part of it (rest being in Strength.concentration as a ratio)
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
154. Extension.extension:substance.extension:strength.extension:measurementPoint
Slice Name	measurementPoint
Definition	For when strength is measured at a particular point or distance. There are products where strength is measured at a particular point. For example, the strength of the ingredient in some inhalers is measured at a particular position relative to the point of aerosolization.
Short	When strength is measured at a particular point or distance
Control	0..1
156. Extension.extension:substance.extension:strength.extension:measurementPoint.url
Control	1..1
Fixed Value	`measurementPoint`
158. Extension.extension:substance.extension:strength.extension:measurementPoint.value[x]
Definition	For when strength is measured at a particular point or distance. There are products where strength is measured at a particular point. For example, the strength of the ingredient in some inhalers is measured at a particular position relative to the point of aerosolization.
Short	When strength is measured at a particular point or distance
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
160. Extension.extension:substance.extension:strength.extension:country
Slice Name	country
Definition	The country or countries for which the strength range applies.
Short	Where the strength range applies
Control	0..*
162. Extension.extension:substance.extension:strength.extension:country.url
Control	1..1
Fixed Value	`country`
164. Extension.extension:substance.extension:strength.extension:country.value[x]
Definition	The country or countries for which the strength range applies.
Short	Where the strength range applies
Binding	For example codes, see R4B_country_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-country-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
166. Extension.extension:substance.extension:strength.extension:referenceStrength
Slice Name	referenceStrength
Definition	Strength expressed in terms of a reference substance. For when the ingredient strength is additionally expressed as equivalent to the strength of some other closely related substance (e.g. salt vs. base). Reference strength represents the strength (quantitative composition) of the active moiety of the active substance. There are situations when the active substance and active moiety are different, therefore both a strength and a reference strength are needed.
Short	Strength expressed in terms of a reference substance
Control	0..*
168. Extension.extension:substance.extension:strength.extension:referenceStrength.extension
Control	1..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
170. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance
Slice Name	substance
Definition	This cross-version extension represents Ingredient.substance.strength.referenceStrength.substance from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	Relevant reference substance
Control	0..1
172. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
174. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept
Slice Name	concept
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.
Short	Reference to a concept (by class)
Control	0..1
176. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept.url
Control	1..1
Fixed Value	`concept`
178. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept.value[x]
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.
Short	Reference to a concept (by class)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
180. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference
Slice Name	reference
Definition	A reference to a resource the provides exact details about the information being referenced.
Short	Reference to a resource (by instance)
Control	0..1
182. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference.url
Control	1..1
Fixed Value	`reference`
184. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference.value[x]
Definition	A reference to a resource the provides exact details about the information being referenced.
Short	Reference to a resource (by instance)
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
186. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.referenceStrength.substance from FHIR R4B
Short	Data type name for Ingredient.substance.strength.referenceStrength.substance from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
188. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype.value[x]
Comments	Must be: CodeableReference
Control	1..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Fixed Value	`CodeableReference`
190. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.url
Control	1..1
Fixed Value	`substance`
192. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x]
Slice Name	strength[x]
Definition	This cross-version extension represents Ingredient.substance.strength.referenceStrength.strength[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	Strength expressed in terms of a reference substance
Control	1..1
194. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension
Control	0..*
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
196. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator
Slice Name	lowNumerator
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Control	0..1
198. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator.url
Control	1..1
Fixed Value	`lowNumerator`
200. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator.value[x]
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
202. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator
Slice Name	highNumerator
Definition	The value of the high limit numerator.
Short	High Numerator limit
Control	0..1
204. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator.url
Control	1..1
Fixed Value	`highNumerator`
206. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator.value[x]
Definition	The value of the high limit numerator.
Short	High Numerator limit
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
208. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator
Slice Name	denominator
Definition	The value of the denominator.
Short	Denominator value
Control	0..1
210. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator.url
Control	1..1
Fixed Value	`denominator`
212. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator.value[x]
Definition	The value of the denominator.
Short	Denominator value
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
214. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.referenceStrength.strength[x] from FHIR R4B
Short	Data type name for Ingredient.substance.strength.referenceStrength.strength[x] from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
216. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype.value[x]
Comments	Must be: RatioRange
Control	1..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Fixed Value	`RatioRange`
218. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].url
Control	1..1
Fixed Value	`strength[x]`
220. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].value[x]
Definition	This cross-version extension represents Ingredient.substance.strength.referenceStrength.strength[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	Strength expressed in terms of a reference substance
Type	Ratio
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
222. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint
Slice Name	measurementPoint
Definition	For when strength is measured at a particular point or distance.
Short	When strength is measured at a particular point or distance
Control	0..1
224. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint.url
Control	1..1
Fixed Value	`measurementPoint`
226. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint.value[x]
Definition	For when strength is measured at a particular point or distance.
Short	When strength is measured at a particular point or distance
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
228. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country
Slice Name	country
Definition	The country or countries for which the strength range applies.
Short	Where the strength range applies
Control	0..*
230. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country.url
Control	1..1
Fixed Value	`country`
232. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country.value[x]
Definition	The country or countries for which the strength range applies.
Short	Where the strength range applies
Binding	For example codes, see R4B_country_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-country-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
234. Extension.extension:substance.extension:strength.extension:referenceStrength.url
Control	1..1
Fixed Value	`referenceStrength`
236. Extension.extension:substance.extension:strength.url
Control	1..1
Fixed Value	`strength`
238. Extension.extension:substance.url
Control	1..1
Fixed Value	`substance`
240. Extension.url
Control	1..1
Fixed Value	`http://hl7.org/fhir/4.3/StructureDefinition/extension-Ingredient`

Guidance on how to interpret the contents of this table can be foundhere

0. Extension
Definition	This cross-version extension represents Ingredient from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4. Optional Extension Element - found in all resources.
Short	An ingredient of a manufactured item or pharmaceutical productOptional Extensions Element
Control	0..* This element is affected by the following invariants: ele-1
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
2. Extension.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	30..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
4. Extension.extension:status
Slice Name	status
Definition	The status of this ingredient. Enables tracking the life-cycle of the content.
Short	draft \| active \| retired \| unknownAdditional content defined by implementations
Control	10..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
6. Extension.extension:status.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`status`
8. Extension.extension:status.value[x]
Definition	The status of this ingredient. Enables tracking the life-cycle of the content. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	draft \| active \| retired \| unknownValue of extension
Control	0..1
Binding	The codes SHALL be taken from For codes, see PublicationStatus (required to `http://hl7.org/fhir/ValueSet/publication-status\|4.0.1`) The lifecycle status of an artifact.
Type	code, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
10. Extension.extension:for
Slice Name	for
Definition	This cross-version extension represents Ingredient.for from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The product which this ingredient is a constituent part ofAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
12. Extension.extension:for.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`for`
14. Extension.extension:for.value[x]
Definition	This cross-version extension represents Ingredient.for from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The product which this ingredient is a constituent part ofValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
16. Extension.extension:role
Slice Name	role
Definition	A classification of the ingredient identifying its purpose within the product, e.g. active, inactive.
Short	Purpose of the ingredient within the product, e.g. active, inactiveAdditional content defined by implementations
Control	10..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
18. Extension.extension:role.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`role`
20. Extension.extension:role.value[x]
Definition	A classification of the ingredient identifying its purpose within the product, e.g. active, inactive. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Purpose of the ingredient within the product, e.g. active, inactiveValue of extension
Control	0..1
Binding	For example codes, see For codes, see R4B_ingredient_role_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-ingredient-role-for-R4\|0.0.1-snapshot-2`) A classification of the ingredient identifying its purpose within the product, e.g. active, inactive.
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
22. Extension.extension:function
Slice Name	function
Definition	A classification of the ingredient identifying its precise purpose(s) in the drug product. This extends the Ingredient.role to add more detail. Example: antioxidant, alkalizing agent.
Short	Precise action within the drug product, e.g. antioxidant, alkalizing agentAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
24. Extension.extension:function.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`function`
26. Extension.extension:function.value[x]
Definition	A classification of the ingredient identifying its precise purpose(s) in the drug product. This extends the Ingredient.role to add more detail. Example: antioxidant, alkalizing agent. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Precise action within the drug product, e.g. antioxidant, alkalizing agentValue of extension
Control	0..1
Binding	For example codes, see For codes, see R4B_ingredient_function_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-ingredient-function-for-R4\|0.0.1-snapshot-2`) A classification of the ingredient identifying its precise purpose(s) in the drug product (beyond e.g. active/inactive).
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
28. Extension.extension:allergenicIndicator
Slice Name	allergenicIndicator
Definition	If the ingredient is a known or suspected allergen. Note that this is a property of the substance, so if a reference to a SubstanceDefinition is used to decribe that (rather than just a code), the allergen information should go there, not here.
Short	If the ingredient is a known or suspected allergenAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
30. Extension.extension:allergenicIndicator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`allergenicIndicator`
32. Extension.extension:allergenicIndicator.value[x]
Definition	If the ingredient is a known or suspected allergen. Note that this is a property of the substance, so if a reference to a SubstanceDefinition is used to decribe that (rather than just a code), the allergen information should go there, not here. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	If the ingredient is a known or suspected allergenValue of extension
Control	0..1
Type	boolean, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
34. Extension.extension:manufacturer
Slice Name	manufacturer
Definition	The organization(s) that manufacture this ingredient. Can be used to indicate: 1) Organizations we are aware of that manufacture this ingredient 2) Specific Manufacturer(s) currently being used 3) Set of organisations allowed to manufacture this ingredient for this product Users must be clear on the application of context relevant to their use case.
Short	An organization that manufactures this ingredientAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
36. Extension.extension:manufacturer.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	10..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
38. Extension.extension:manufacturer.extension:role
Slice Name	role
Definition	The way in which this manufacturer is associated with the ingredient. For example whether it is a possible one (others allowed), or an exclusive authorized one for this ingredient. Note that this is not the manufacturing process role.
Short	allowed \| possible \| actualAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
40. Extension.extension:manufacturer.extension:role.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`role`
42. Extension.extension:manufacturer.extension:role.value[x]
Definition	The way in which this manufacturer is associated with the ingredient. For example whether it is a possible one (others allowed), or an exclusive authorized one for this ingredient. Note that this is not the manufacturing process role. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	allowed \| possible \| actualValue of extension
Control	0..1
Binding	The codes SHALL be taken from For codes, see R4B_ingredient_manufacturer_role_for_R4 (0.0.1-snapshot-2) (required to `http://hl7.org/fhir/4.3/ValueSet/R4B-ingredient-manufacturer-role-for-R4\|0.0.1-snapshot-2`) The way in which this manufacturer is associated with the ingredient.
Type	code, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
44. Extension.extension:manufacturer.extension:manufacturer
Slice Name	manufacturer
Definition	This cross-version extension represents Ingredient.manufacturer.manufacturer from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	An organization that manufactures this ingredientAdditional content defined by implementations
Control	10..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
46. Extension.extension:manufacturer.extension:manufacturer.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`manufacturer`
48. Extension.extension:manufacturer.extension:manufacturer.value[x]
Definition	This cross-version extension represents Ingredient.manufacturer.manufacturer from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	An organization that manufactures this ingredientValue of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
50. Extension.extension:manufacturer.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`manufacturer`
52. Extension.extension:substance
Slice Name	substance
Definition	This cross-version extension represents Ingredient.substance from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The substance that comprises this ingredientAdditional content defined by implementations
Control	10..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
54. Extension.extension:substance.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	10..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
56. Extension.extension:substance.extension:code
Slice Name	code
Definition	A code or full resource that represents the ingredient's substance.
Short	A code or full resource that represents the ingredient substanceAdditional content defined by implementations
Control	10..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
58. Extension.extension:substance.extension:code.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
60. Extension.extension:substance.extension:code.extension:concept
Slice Name	concept
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.
Short	Reference to a concept (by class)Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
62. Extension.extension:substance.extension:code.extension:concept.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`concept`
64. Extension.extension:substance.extension:code.extension:concept.value[x]
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Reference to a concept (by class)Value of extension
Control	0..1
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
66. Extension.extension:substance.extension:code.extension:reference
Slice Name	reference
Definition	A reference to a resource the provides exact details about the information being referenced.
Short	Reference to a resource (by instance)Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
68. Extension.extension:substance.extension:code.extension:reference.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`reference`
70. Extension.extension:substance.extension:code.extension:reference.value[x]
Definition	A reference to a resource the provides exact details about the information being referenced. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Reference to a resource (by instance)Value of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
72. Extension.extension:substance.extension:code.extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.code from FHIR R4B
Short	Data type name for Ingredient.substance.code from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
74. Extension.extension:substance.extension:code.extension:_datatype.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..0*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
76. Extension.extension:substance.extension:code.extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
78. Extension.extension:substance.extension:code.extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: CodeableReference
Control	10..1 This element is affected by the following invariants: ext-1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`CodeableReference`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
80. Extension.extension:substance.extension:code.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`code`
82. Extension.extension:substance.extension:strength
Slice Name	strength
Definition	The quantity of substance in the unit of presentation, or in the volume (or mass) of the single pharmaceutical product or manufactured item. The allowed repetitions do not represent different strengths, but are different representations - mathematically equivalent - of a single strength.
Short	The quantity of substance, per presentation, or per volume or mass, and type of quantityAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
84. Extension.extension:substance.extension:strength.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
86. Extension.extension:substance.extension:strength.extension:presentation[x]
Slice Name	presentation[x]
Definition	The quantity of substance in the unit of presentation, or in the volume (or mass) of the single pharmaceutical product or manufactured item. Unit of presentation refers to the quantity that the item occurs in e.g. a strength per tablet size, perhaps 'per 20mg' (the size of the tablet). It is not generally normalized as a unitary unit, which would be 'per mg').
Short	The quantity of substance in the unit of presentationAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
88. Extension.extension:substance.extension:strength.extension:presentation[x].extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
90. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator
Slice Name	lowNumerator
Definition	The value of the low limit numerator.
Short	Low Numerator limitAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
92. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`lowNumerator`
94. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator.value[x]
Definition	The value of the low limit numerator. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Low Numerator limitValue of extension
Control	0..1
Type	Quantity(SimpleQuantity), date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
96. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator
Slice Name	highNumerator
Definition	The value of the high limit numerator.
Short	High Numerator limitAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
98. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`highNumerator`
100. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator.value[x]
Definition	The value of the high limit numerator. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	High Numerator limitValue of extension
Control	0..1
Type	Quantity(SimpleQuantity), date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
102. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator
Slice Name	denominator
Definition	The value of the denominator.
Short	Denominator valueAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
104. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`denominator`
106. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator.value[x]
Definition	The value of the denominator. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Denominator valueValue of extension
Control	0..1
Type	Quantity(SimpleQuantity), date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
108. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.presentation[x] from FHIR R4B
Short	Data type name for Ingredient.substance.strength.presentation[x] from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
110. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..0*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
112. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
114. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: RatioRange
Control	10..1 This element is affected by the following invariants: ext-1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`RatioRange`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
116. Extension.extension:substance.extension:strength.extension:presentation[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`presentation[x]`
118. Extension.extension:substance.extension:strength.extension:presentation[x].value[x]
Definition	The quantity of substance in the unit of presentation, or in the volume (or mass) of the single pharmaceutical product or manufactured item. Unit of presentation refers to the quantity that the item occurs in e.g. a strength per tablet size, perhaps 'per 20mg' (the size of the tablet). It is not generally normalized as a unitary unit, which would be 'per mg'). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The quantity of substance in the unit of presentationValue of extension
Control	0..1
Type	Ratio, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
120. Extension.extension:substance.extension:strength.extension:textPresentation
Slice Name	textPresentation
Definition	A textual represention of either the whole of the presentation strength or a part of it - with the rest being in Strength.presentation as a ratio.
Short	Text of either the whole presentation strength or a part of it (rest being in Strength.presentation as a ratio)Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
122. Extension.extension:substance.extension:strength.extension:textPresentation.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`textPresentation`
124. Extension.extension:substance.extension:strength.extension:textPresentation.value[x]
Definition	A textual represention of either the whole of the presentation strength or a part of it - with the rest being in Strength.presentation as a ratio. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Text of either the whole presentation strength or a part of it (rest being in Strength.presentation as a ratio)Value of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
126. Extension.extension:substance.extension:strength.extension:concentration[x]
Slice Name	concentration[x]
Definition	This cross-version extension represents Ingredient.substance.strength.concentration[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The strength per unitary volume (or mass)Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
128. Extension.extension:substance.extension:strength.extension:concentration[x].extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
130. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator
Slice Name	lowNumerator
Definition	The value of the low limit numerator.
Short	Low Numerator limitAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
132. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`lowNumerator`
134. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator.value[x]
Definition	The value of the low limit numerator. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Low Numerator limitValue of extension
Control	0..1
Type	Quantity(SimpleQuantity), date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
136. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator
Slice Name	highNumerator
Definition	The value of the high limit numerator.
Short	High Numerator limitAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
138. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`highNumerator`
140. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator.value[x]
Definition	The value of the high limit numerator. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	High Numerator limitValue of extension
Control	0..1
Type	Quantity(SimpleQuantity), date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
142. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator
Slice Name	denominator
Definition	The value of the denominator.
Short	Denominator valueAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
144. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`denominator`
146. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator.value[x]
Definition	The value of the denominator. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Denominator valueValue of extension
Control	0..1
Type	Quantity(SimpleQuantity), date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
148. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.concentration[x] from FHIR R4B
Short	Data type name for Ingredient.substance.strength.concentration[x] from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
150. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..0*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
152. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
154. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: RatioRange
Control	10..1 This element is affected by the following invariants: ext-1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`RatioRange`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
156. Extension.extension:substance.extension:strength.extension:concentration[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`concentration[x]`
158. Extension.extension:substance.extension:strength.extension:concentration[x].value[x]
Definition	This cross-version extension represents Ingredient.substance.strength.concentration[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	The strength per unitary volume (or mass)Value of extension
Control	0..1
Type	Ratio, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
160. Extension.extension:substance.extension:strength.extension:textConcentration
Slice Name	textConcentration
Definition	A textual represention of either the whole of the concentration strength or a part of it - with the rest being in Strength.concentration as a ratio.
Short	Text of either the whole concentration strength or a part of it (rest being in Strength.concentration as a ratio)Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
162. Extension.extension:substance.extension:strength.extension:textConcentration.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`textConcentration`
164. Extension.extension:substance.extension:strength.extension:textConcentration.value[x]
Definition	A textual represention of either the whole of the concentration strength or a part of it - with the rest being in Strength.concentration as a ratio. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Text of either the whole concentration strength or a part of it (rest being in Strength.concentration as a ratio)Value of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
166. Extension.extension:substance.extension:strength.extension:measurementPoint
Slice Name	measurementPoint
Definition	For when strength is measured at a particular point or distance. There are products where strength is measured at a particular point. For example, the strength of the ingredient in some inhalers is measured at a particular position relative to the point of aerosolization.
Short	When strength is measured at a particular point or distanceAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
168. Extension.extension:substance.extension:strength.extension:measurementPoint.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`measurementPoint`
170. Extension.extension:substance.extension:strength.extension:measurementPoint.value[x]
Definition	For when strength is measured at a particular point or distance. There are products where strength is measured at a particular point. For example, the strength of the ingredient in some inhalers is measured at a particular position relative to the point of aerosolization. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	When strength is measured at a particular point or distanceValue of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
172. Extension.extension:substance.extension:strength.extension:country
Slice Name	country
Definition	The country or countries for which the strength range applies.
Short	Where the strength range appliesAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
174. Extension.extension:substance.extension:strength.extension:country.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`country`
176. Extension.extension:substance.extension:strength.extension:country.value[x]
Definition	The country or countries for which the strength range applies. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Where the strength range appliesValue of extension
Control	0..1
Binding	For example codes, see For codes, see R4B_country_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-country-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
178. Extension.extension:substance.extension:strength.extension:referenceStrength
Slice Name	referenceStrength
Definition	Strength expressed in terms of a reference substance. For when the ingredient strength is additionally expressed as equivalent to the strength of some other closely related substance (e.g. salt vs. base). Reference strength represents the strength (quantitative composition) of the active moiety of the active substance. There are situations when the active substance and active moiety are different, therefore both a strength and a reference strength are needed.
Short	Strength expressed in terms of a reference substanceAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
180. Extension.extension:substance.extension:strength.extension:referenceStrength.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	10..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
182. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance
Slice Name	substance
Definition	This cross-version extension represents Ingredient.substance.strength.referenceStrength.substance from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	Relevant reference substanceAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
184. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
186. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept
Slice Name	concept
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.
Short	Reference to a concept (by class)Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
188. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`concept`
190. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept.value[x]
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Reference to a concept (by class)Value of extension
Control	0..1
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
192. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference
Slice Name	reference
Definition	A reference to a resource the provides exact details about the information being referenced.
Short	Reference to a resource (by instance)Additional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
194. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`reference`
196. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference.value[x]
Definition	A reference to a resource the provides exact details about the information being referenced. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Reference to a resource (by instance)Value of extension
Control	0..1
Type	Reference, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
198. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.referenceStrength.substance from FHIR R4B
Short	Data type name for Ingredient.substance.strength.referenceStrength.substance from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
200. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..0*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
202. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
204. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: CodeableReference
Control	10..1 This element is affected by the following invariants: ext-1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`CodeableReference`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
206. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`substance`
208. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x]
Slice Name	strength[x]
Definition	This cross-version extension represents Ingredient.substance.strength.referenceStrength.strength[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	Strength expressed in terms of a reference substanceAdditional content defined by implementations
Control	10..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
210. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and ClosedOpen, and can be differentiated using the following discriminators: value @ url
212. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator
Slice Name	lowNumerator
Definition	The value of the low limit numerator.
Short	Low Numerator limitAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
214. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`lowNumerator`
216. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator.value[x]
Definition	The value of the low limit numerator. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Low Numerator limitValue of extension
Control	0..1
Type	Quantity(SimpleQuantity), date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
218. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator
Slice Name	highNumerator
Definition	The value of the high limit numerator.
Short	High Numerator limitAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
220. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`highNumerator`
222. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator.value[x]
Definition	The value of the high limit numerator. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	High Numerator limitValue of extension
Control	0..1
Type	Quantity(SimpleQuantity), date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
224. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator
Slice Name	denominator
Definition	The value of the denominator.
Short	Denominator valueAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
226. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`denominator`
228. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator.value[x]
Definition	The value of the denominator. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Denominator valueValue of extension
Control	0..1
Type	Quantity(SimpleQuantity), date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
230. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.referenceStrength.strength[x] from FHIR R4B
Short	Data type name for Ingredient.substance.strength.referenceStrength.strength[x] from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
232. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..0*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
234. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
236. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list). Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: RatioRange
Control	10..1 This element is affected by the following invariants: ext-1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`RatioRange`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
238. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`strength[x]`
240. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].value[x]
Definition	This cross-version extension represents Ingredient.substance.strength.referenceStrength.strength[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Strength expressed in terms of a reference substanceValue of extension
Control	0..1
Type	Ratio, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
242. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint
Slice Name	measurementPoint
Definition	For when strength is measured at a particular point or distance.
Short	When strength is measured at a particular point or distanceAdditional content defined by implementations
Control	0..1*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
244. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`measurementPoint`
246. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint.value[x]
Definition	For when strength is measured at a particular point or distance. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	When strength is measured at a particular point or distanceValue of extension
Control	0..1
Type	string, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, CodeableConcept, ParameterDefinition, dateTime, code, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
248. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country
Slice Name	country
Definition	The country or countries for which the strength range applies.
Short	Where the strength range appliesAdditional content defined by implementations
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
250. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`country`
252. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country.value[x]
Definition	The country or countries for which the strength range applies. Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Where the strength range appliesValue of extension
Control	0..1
Binding	For example codes, see For codes, see R4B_country_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-country-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept, date, Meta, Address, Attachment, integer, Count, DataRequirement, Dosage, uuid, Identifier, Coding, SampledData, id, positiveInt, Distance, Period, Duration, canonical, Range, RelatedArtifact, base64Binary, UsageContext, Timing, decimal, ParameterDefinition, dateTime, code, string, Contributor, oid, instant, ContactPoint, HumanName, Money, markdown, Ratio, Age, Reference, TriggerDefinition, Quantity, uri, url, Annotation, ContactDetail, boolean, Expression, Signature, unsignedInt, time
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
254. Extension.extension:substance.extension:strength.extension:referenceStrength.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`referenceStrength`
256. Extension.extension:substance.extension:strength.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`strength`
258. Extension.extension:substance.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`substance`
260. Extension.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/4.3/StructureDefinition/extension-Ingredient`

Guidance on how to interpret the contents of this table can be foundhere

0. Extension
Definition	This cross-version extension represents Ingredient from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	An ingredient of a manufactured item or pharmaceutical product
Control	0..* This element is affected by the following invariants: ele-1
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2. Extension.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4. Extension.extension
Definition	An Extension
Short	Extension
Control	3..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
6. Extension.extension:status
Slice Name	status
Definition	The status of this ingredient. Enables tracking the life-cycle of the content.
Short	draft \| active \| retired \| unknown
Control	1..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
8. Extension.extension:status.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
10. Extension.extension:status.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
12. Extension.extension:status.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`status`
14. Extension.extension:status.value[x]
Definition	The status of this ingredient. Enables tracking the life-cycle of the content.
Short	draft \| active \| retired \| unknown
Control	0..1
Binding	The codes SHALL be taken from PublicationStatus (required to `http://hl7.org/fhir/ValueSet/publication-status\|4.0.1`) The lifecycle status of an artifact.
Type	code
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
16. Extension.extension:for
Slice Name	for
Definition	This cross-version extension represents Ingredient.for from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The product which this ingredient is a constituent part of
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
18. Extension.extension:for.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
20. Extension.extension:for.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
22. Extension.extension:for.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`for`
24. Extension.extension:for.value[x]
Definition	This cross-version extension represents Ingredient.for from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The product which this ingredient is a constituent part of
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
26. Extension.extension:role
Slice Name	role
Definition	A classification of the ingredient identifying its purpose within the product, e.g. active, inactive.
Short	Purpose of the ingredient within the product, e.g. active, inactive
Control	1..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
28. Extension.extension:role.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
30. Extension.extension:role.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
32. Extension.extension:role.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`role`
34. Extension.extension:role.value[x]
Definition	A classification of the ingredient identifying its purpose within the product, e.g. active, inactive.
Short	Purpose of the ingredient within the product, e.g. active, inactive
Control	0..1
Binding	For example codes, see R4B_ingredient_role_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-ingredient-role-for-R4\|0.0.1-snapshot-2`) A classification of the ingredient identifying its purpose within the product, e.g. active, inactive.
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
36. Extension.extension:function
Slice Name	function
Definition	A classification of the ingredient identifying its precise purpose(s) in the drug product. This extends the Ingredient.role to add more detail. Example: antioxidant, alkalizing agent.
Short	Precise action within the drug product, e.g. antioxidant, alkalizing agent
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
38. Extension.extension:function.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
40. Extension.extension:function.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
42. Extension.extension:function.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`function`
44. Extension.extension:function.value[x]
Definition	A classification of the ingredient identifying its precise purpose(s) in the drug product. This extends the Ingredient.role to add more detail. Example: antioxidant, alkalizing agent.
Short	Precise action within the drug product, e.g. antioxidant, alkalizing agent
Control	0..1
Binding	For example codes, see R4B_ingredient_function_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-ingredient-function-for-R4\|0.0.1-snapshot-2`) A classification of the ingredient identifying its precise purpose(s) in the drug product (beyond e.g. active/inactive).
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
46. Extension.extension:allergenicIndicator
Slice Name	allergenicIndicator
Definition	If the ingredient is a known or suspected allergen. Note that this is a property of the substance, so if a reference to a SubstanceDefinition is used to decribe that (rather than just a code), the allergen information should go there, not here.
Short	If the ingredient is a known or suspected allergen
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
48. Extension.extension:allergenicIndicator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
50. Extension.extension:allergenicIndicator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
52. Extension.extension:allergenicIndicator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`allergenicIndicator`
54. Extension.extension:allergenicIndicator.value[x]
Definition	If the ingredient is a known or suspected allergen. Note that this is a property of the substance, so if a reference to a SubstanceDefinition is used to decribe that (rather than just a code), the allergen information should go there, not here.
Short	If the ingredient is a known or suspected allergen
Control	0..1
Type	boolean
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
56. Extension.extension:manufacturer
Slice Name	manufacturer
Definition	The organization(s) that manufacture this ingredient. Can be used to indicate: 1) Organizations we are aware of that manufacture this ingredient 2) Specific Manufacturer(s) currently being used 3) Set of organisations allowed to manufacture this ingredient for this product Users must be clear on the application of context relevant to their use case.
Short	An organization that manufactures this ingredient
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
58. Extension.extension:manufacturer.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
60. Extension.extension:manufacturer.extension
Definition	An Extension
Short	Extension
Control	1..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
62. Extension.extension:manufacturer.extension:role
Slice Name	role
Definition	The way in which this manufacturer is associated with the ingredient. For example whether it is a possible one (others allowed), or an exclusive authorized one for this ingredient. Note that this is not the manufacturing process role.
Short	allowed \| possible \| actual
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
64. Extension.extension:manufacturer.extension:role.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
66. Extension.extension:manufacturer.extension:role.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
68. Extension.extension:manufacturer.extension:role.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`role`
70. Extension.extension:manufacturer.extension:role.value[x]
Definition	The way in which this manufacturer is associated with the ingredient. For example whether it is a possible one (others allowed), or an exclusive authorized one for this ingredient. Note that this is not the manufacturing process role.
Short	allowed \| possible \| actual
Control	0..1
Binding	The codes SHALL be taken from R4B_ingredient_manufacturer_role_for_R4 (0.0.1-snapshot-2) (required to `http://hl7.org/fhir/4.3/ValueSet/R4B-ingredient-manufacturer-role-for-R4\|0.0.1-snapshot-2`) The way in which this manufacturer is associated with the ingredient.
Type	code
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
72. Extension.extension:manufacturer.extension:manufacturer
Slice Name	manufacturer
Definition	This cross-version extension represents Ingredient.manufacturer.manufacturer from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	An organization that manufactures this ingredient
Control	1..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
74. Extension.extension:manufacturer.extension:manufacturer.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
76. Extension.extension:manufacturer.extension:manufacturer.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
78. Extension.extension:manufacturer.extension:manufacturer.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`manufacturer`
80. Extension.extension:manufacturer.extension:manufacturer.value[x]
Definition	This cross-version extension represents Ingredient.manufacturer.manufacturer from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	An organization that manufactures this ingredient
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
82. Extension.extension:manufacturer.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`manufacturer`
84. Extension.extension:manufacturer.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
86. Extension.extension:substance
Slice Name	substance
Definition	This cross-version extension represents Ingredient.substance from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The substance that comprises this ingredient
Control	1..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
88. Extension.extension:substance.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
90. Extension.extension:substance.extension
Definition	An Extension
Short	Extension
Control	1..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
92. Extension.extension:substance.extension:code
Slice Name	code
Definition	A code or full resource that represents the ingredient's substance.
Short	A code or full resource that represents the ingredient substance
Control	1..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
94. Extension.extension:substance.extension:code.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
96. Extension.extension:substance.extension:code.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
98. Extension.extension:substance.extension:code.extension:concept
Slice Name	concept
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.
Short	Reference to a concept (by class)
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
100. Extension.extension:substance.extension:code.extension:concept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
102. Extension.extension:substance.extension:code.extension:concept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
104. Extension.extension:substance.extension:code.extension:concept.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`concept`
106. Extension.extension:substance.extension:code.extension:concept.value[x]
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.
Short	Reference to a concept (by class)
Control	0..1
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
108. Extension.extension:substance.extension:code.extension:reference
Slice Name	reference
Definition	A reference to a resource the provides exact details about the information being referenced.
Short	Reference to a resource (by instance)
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
110. Extension.extension:substance.extension:code.extension:reference.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
112. Extension.extension:substance.extension:code.extension:reference.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
114. Extension.extension:substance.extension:code.extension:reference.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`reference`
116. Extension.extension:substance.extension:code.extension:reference.value[x]
Definition	A reference to a resource the provides exact details about the information being referenced.
Short	Reference to a resource (by instance)
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
118. Extension.extension:substance.extension:code.extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.code from FHIR R4B
Short	Data type name for Ingredient.substance.code from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
120. Extension.extension:substance.extension:code.extension:_datatype.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
122. Extension.extension:substance.extension:code.extension:_datatype.extension
Definition	An Extension
Short	Extension
Control	0..0
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
124. Extension.extension:substance.extension:code.extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
126. Extension.extension:substance.extension:code.extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: CodeableReference
Control	1..1 This element is affected by the following invariants: ext-1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`CodeableReference`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
128. Extension.extension:substance.extension:code.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`code`
130. Extension.extension:substance.extension:code.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
132. Extension.extension:substance.extension:strength
Slice Name	strength
Definition	The quantity of substance in the unit of presentation, or in the volume (or mass) of the single pharmaceutical product or manufactured item. The allowed repetitions do not represent different strengths, but are different representations - mathematically equivalent - of a single strength.
Short	The quantity of substance, per presentation, or per volume or mass, and type of quantity
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
134. Extension.extension:substance.extension:strength.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
136. Extension.extension:substance.extension:strength.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
138. Extension.extension:substance.extension:strength.extension:presentation[x]
Slice Name	presentation[x]
Definition	The quantity of substance in the unit of presentation, or in the volume (or mass) of the single pharmaceutical product or manufactured item. Unit of presentation refers to the quantity that the item occurs in e.g. a strength per tablet size, perhaps 'per 20mg' (the size of the tablet). It is not generally normalized as a unitary unit, which would be 'per mg').
Short	The quantity of substance in the unit of presentation
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
140. Extension.extension:substance.extension:strength.extension:presentation[x].id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
142. Extension.extension:substance.extension:strength.extension:presentation[x].extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
144. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator
Slice Name	lowNumerator
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
146. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
148. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
150. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`lowNumerator`
152. Extension.extension:substance.extension:strength.extension:presentation[x].extension:lowNumerator.value[x]
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Control	0..1
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
154. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator
Slice Name	highNumerator
Definition	The value of the high limit numerator.
Short	High Numerator limit
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
156. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
158. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
160. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`highNumerator`
162. Extension.extension:substance.extension:strength.extension:presentation[x].extension:highNumerator.value[x]
Definition	The value of the high limit numerator.
Short	High Numerator limit
Control	0..1
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
164. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator
Slice Name	denominator
Definition	The value of the denominator.
Short	Denominator value
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
166. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
168. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
170. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`denominator`
172. Extension.extension:substance.extension:strength.extension:presentation[x].extension:denominator.value[x]
Definition	The value of the denominator.
Short	Denominator value
Control	0..1
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
174. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.presentation[x] from FHIR R4B
Short	Data type name for Ingredient.substance.strength.presentation[x] from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
176. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
178. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype.extension
Definition	An Extension
Short	Extension
Control	0..0
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
180. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
182. Extension.extension:substance.extension:strength.extension:presentation[x].extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: RatioRange
Control	1..1 This element is affected by the following invariants: ext-1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`RatioRange`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
184. Extension.extension:substance.extension:strength.extension:presentation[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`presentation[x]`
186. Extension.extension:substance.extension:strength.extension:presentation[x].value[x]
Definition	The quantity of substance in the unit of presentation, or in the volume (or mass) of the single pharmaceutical product or manufactured item. Unit of presentation refers to the quantity that the item occurs in e.g. a strength per tablet size, perhaps 'per 20mg' (the size of the tablet). It is not generally normalized as a unitary unit, which would be 'per mg').
Short	The quantity of substance in the unit of presentation
Control	0..1
Type	Ratio
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
188. Extension.extension:substance.extension:strength.extension:textPresentation
Slice Name	textPresentation
Definition	A textual represention of either the whole of the presentation strength or a part of it - with the rest being in Strength.presentation as a ratio.
Short	Text of either the whole presentation strength or a part of it (rest being in Strength.presentation as a ratio)
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
190. Extension.extension:substance.extension:strength.extension:textPresentation.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
192. Extension.extension:substance.extension:strength.extension:textPresentation.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
194. Extension.extension:substance.extension:strength.extension:textPresentation.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`textPresentation`
196. Extension.extension:substance.extension:strength.extension:textPresentation.value[x]
Definition	A textual represention of either the whole of the presentation strength or a part of it - with the rest being in Strength.presentation as a ratio.
Short	Text of either the whole presentation strength or a part of it (rest being in Strength.presentation as a ratio)
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
198. Extension.extension:substance.extension:strength.extension:concentration[x]
Slice Name	concentration[x]
Definition	This cross-version extension represents Ingredient.substance.strength.concentration[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The strength per unitary volume (or mass)
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
200. Extension.extension:substance.extension:strength.extension:concentration[x].id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
202. Extension.extension:substance.extension:strength.extension:concentration[x].extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
204. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator
Slice Name	lowNumerator
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
206. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
208. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
210. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`lowNumerator`
212. Extension.extension:substance.extension:strength.extension:concentration[x].extension:lowNumerator.value[x]
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Control	0..1
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
214. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator
Slice Name	highNumerator
Definition	The value of the high limit numerator.
Short	High Numerator limit
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
216. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
218. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
220. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`highNumerator`
222. Extension.extension:substance.extension:strength.extension:concentration[x].extension:highNumerator.value[x]
Definition	The value of the high limit numerator.
Short	High Numerator limit
Control	0..1
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
224. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator
Slice Name	denominator
Definition	The value of the denominator.
Short	Denominator value
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
226. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
228. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
230. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`denominator`
232. Extension.extension:substance.extension:strength.extension:concentration[x].extension:denominator.value[x]
Definition	The value of the denominator.
Short	Denominator value
Control	0..1
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
234. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.concentration[x] from FHIR R4B
Short	Data type name for Ingredient.substance.strength.concentration[x] from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
236. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
238. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype.extension
Definition	An Extension
Short	Extension
Control	0..0
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
240. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
242. Extension.extension:substance.extension:strength.extension:concentration[x].extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: RatioRange
Control	1..1 This element is affected by the following invariants: ext-1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`RatioRange`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
244. Extension.extension:substance.extension:strength.extension:concentration[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`concentration[x]`
246. Extension.extension:substance.extension:strength.extension:concentration[x].value[x]
Definition	This cross-version extension represents Ingredient.substance.strength.concentration[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	The strength per unitary volume (or mass)
Control	0..1
Type	Ratio
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
248. Extension.extension:substance.extension:strength.extension:textConcentration
Slice Name	textConcentration
Definition	A textual represention of either the whole of the concentration strength or a part of it - with the rest being in Strength.concentration as a ratio.
Short	Text of either the whole concentration strength or a part of it (rest being in Strength.concentration as a ratio)
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
250. Extension.extension:substance.extension:strength.extension:textConcentration.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
252. Extension.extension:substance.extension:strength.extension:textConcentration.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
254. Extension.extension:substance.extension:strength.extension:textConcentration.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`textConcentration`
256. Extension.extension:substance.extension:strength.extension:textConcentration.value[x]
Definition	A textual represention of either the whole of the concentration strength or a part of it - with the rest being in Strength.concentration as a ratio.
Short	Text of either the whole concentration strength or a part of it (rest being in Strength.concentration as a ratio)
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
258. Extension.extension:substance.extension:strength.extension:measurementPoint
Slice Name	measurementPoint
Definition	For when strength is measured at a particular point or distance. There are products where strength is measured at a particular point. For example, the strength of the ingredient in some inhalers is measured at a particular position relative to the point of aerosolization.
Short	When strength is measured at a particular point or distance
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
260. Extension.extension:substance.extension:strength.extension:measurementPoint.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
262. Extension.extension:substance.extension:strength.extension:measurementPoint.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
264. Extension.extension:substance.extension:strength.extension:measurementPoint.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`measurementPoint`
266. Extension.extension:substance.extension:strength.extension:measurementPoint.value[x]
Definition	For when strength is measured at a particular point or distance. There are products where strength is measured at a particular point. For example, the strength of the ingredient in some inhalers is measured at a particular position relative to the point of aerosolization.
Short	When strength is measured at a particular point or distance
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
268. Extension.extension:substance.extension:strength.extension:country
Slice Name	country
Definition	The country or countries for which the strength range applies.
Short	Where the strength range applies
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
270. Extension.extension:substance.extension:strength.extension:country.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
272. Extension.extension:substance.extension:strength.extension:country.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
274. Extension.extension:substance.extension:strength.extension:country.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`country`
276. Extension.extension:substance.extension:strength.extension:country.value[x]
Definition	The country or countries for which the strength range applies.
Short	Where the strength range applies
Control	0..1
Binding	For example codes, see R4B_country_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-country-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
278. Extension.extension:substance.extension:strength.extension:referenceStrength
Slice Name	referenceStrength
Definition	Strength expressed in terms of a reference substance. For when the ingredient strength is additionally expressed as equivalent to the strength of some other closely related substance (e.g. salt vs. base). Reference strength represents the strength (quantitative composition) of the active moiety of the active substance. There are situations when the active substance and active moiety are different, therefore both a strength and a reference strength are needed.
Short	Strength expressed in terms of a reference substance
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
280. Extension.extension:substance.extension:strength.extension:referenceStrength.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
282. Extension.extension:substance.extension:strength.extension:referenceStrength.extension
Definition	An Extension
Short	Extension
Control	1..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
284. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance
Slice Name	substance
Definition	This cross-version extension represents Ingredient.substance.strength.referenceStrength.substance from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	Relevant reference substance
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
286. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
288. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
290. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept
Slice Name	concept
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.
Short	Reference to a concept (by class)
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
292. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
294. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
296. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`concept`
298. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:concept.value[x]
Definition	A reference to a concept - e.g. the information is identified by its general class to the degree of precision found in the terminology.
Short	Reference to a concept (by class)
Control	0..1
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
300. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference
Slice Name	reference
Definition	A reference to a resource the provides exact details about the information being referenced.
Short	Reference to a resource (by instance)
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
302. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
304. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
306. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`reference`
308. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:reference.value[x]
Definition	A reference to a resource the provides exact details about the information being referenced.
Short	Reference to a resource (by instance)
Control	0..1
Type	Reference
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
310. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.referenceStrength.substance from FHIR R4B
Short	Data type name for Ingredient.substance.strength.referenceStrength.substance from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
312. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
314. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype.extension
Definition	An Extension
Short	Extension
Control	0..0
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
316. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
318. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: CodeableReference
Control	1..1 This element is affected by the following invariants: ext-1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`CodeableReference`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
320. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`substance`
322. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:substance.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
324. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x]
Slice Name	strength[x]
Definition	This cross-version extension represents Ingredient.substance.strength.referenceStrength.strength[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	Strength expressed in terms of a reference substance
Control	1..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
326. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
328. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Closed, and can be differentiated using the following discriminators: value @ url
330. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator
Slice Name	lowNumerator
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
332. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
334. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
336. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`lowNumerator`
338. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:lowNumerator.value[x]
Definition	The value of the low limit numerator.
Short	Low Numerator limit
Control	0..1
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
340. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator
Slice Name	highNumerator
Definition	The value of the high limit numerator.
Short	High Numerator limit
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
342. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
344. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
346. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`highNumerator`
348. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:highNumerator.value[x]
Definition	The value of the high limit numerator.
Short	High Numerator limit
Control	0..1
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
350. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator
Slice Name	denominator
Definition	The value of the denominator.
Short	Denominator value
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
352. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
354. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
356. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`denominator`
358. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:denominator.value[x]
Definition	The value of the denominator.
Short	Denominator value
Control	0..1
Type	Quantity(SimpleQuantity)
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
360. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype
Slice Name	_datatype
Definition	Data type name for Ingredient.substance.strength.referenceStrength.strength[x] from FHIR R4B
Short	Data type name for Ingredient.substance.strength.referenceStrength.strength[x] from FHIR R4B
Control	0..1
Type	Extension(Datatype) (Extension Type: string)
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
362. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
364. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype.extension
Definition	An Extension
Short	Extension
Control	0..0
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
366. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/StructureDefinition/_datatype`
368. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].extension:_datatype.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Comments	Must be: RatioRange
Control	1..1 This element is affected by the following invariants: ext-1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Fixed Value	`RatioRange`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
370. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`strength[x]`
372. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:strength[x].value[x]
Definition	This cross-version extension represents Ingredient.substance.strength.referenceStrength.strength[x] from http://hl7.org/fhir/StructureDefinition/Ingredient\|4.3.0 for use in FHIR R4.
Short	Strength expressed in terms of a reference substance
Control	0..1
Type	Ratio
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
374. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint
Slice Name	measurementPoint
Definition	For when strength is measured at a particular point or distance.
Short	When strength is measured at a particular point or distance
Control	0..1
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
376. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
378. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
380. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`measurementPoint`
382. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:measurementPoint.value[x]
Definition	For when strength is measured at a particular point or distance.
Short	When strength is measured at a particular point or distance
Control	0..1
Type	string
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
384. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country
Slice Name	country
Definition	The country or countries for which the strength range applies.
Short	Where the strength range applies
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
386. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
388. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `Extension.extension.extension.extension.extension.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
390. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`country`
392. Extension.extension:substance.extension:strength.extension:referenceStrength.extension:country.value[x]
Definition	The country or countries for which the strength range applies.
Short	Where the strength range applies
Control	0..1
Binding	For example codes, see R4B_country_for_R4 (0.0.1-snapshot-2) (example to `http://hl7.org/fhir/4.3/ValueSet/R4B-country-for-R4\|0.0.1-snapshot-2`) Jurisdiction codes
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
394. Extension.extension:substance.extension:strength.extension:referenceStrength.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`referenceStrength`
396. Extension.extension:substance.extension:strength.extension:referenceStrength.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
398. Extension.extension:substance.extension:strength.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`strength`
400. Extension.extension:substance.extension:strength.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
402. Extension.extension:substance.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`substance`
404. Extension.extension:substance.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
406. Extension.url
Definition	Source of the definition for the extension code - a logical name or a URL.
Short	identifies the meaning of the extension
Comments	The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Control	1..1
Type	uri
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
Fixed Value	`http://hl7.org/fhir/4.3/StructureDefinition/extension-Ingredient`
408. Extension.value[x]
Definition	Value of extension - must be one of a constrained set of the data types (see Extensibility for a list).
Short	Value of extension
Control	0..1
Type	Choice of: base64Binary, boolean, canonical, code, date, dateTime, decimal, id, instant, integer, markdown, oid, positiveInt, string, time, unsignedInt, uri, url, uuid, Address, Age, Annotation, Attachment, CodeableConcept, Coding, ContactPoint, Count, Distance, Duration, HumanName, Identifier, Money, Period, Quantity, Range, Ratio, Reference, SampledData, Signature, Timing, ContactDetail, Contributor, DataRequirement, Expression, ParameterDefinition, RelatedArtifact, TriggerDefinition, UsageContext, Dosage, Meta
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)