Information about a medication that is used to support knowledge.

A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc.

These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope. This is allowed to be a Parameters resource if and only if it is referenced by a resource that provides context/meaning.

This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags in their meta elements, but SHALL NOT have security labels.

An Extension

R4: MedicationKnowledge.manufacturer (new:Reference(Organization))

Element MedicationKnowledge.manufacturer has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.manufacturer has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.doseForm (new:CodeableConcept)

Element MedicationKnowledge.doseForm has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.doseForm has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element). When Medication is referenced from MedicationRequest, this is the ordered form. When Medication is referenced within MedicationDispense, this is the dispensed form. When Medication is referenced within MedicationAdministration, this is administered form.

R4: MedicationKnowledge.amount (new:Quantity[SimpleQuantity])

Element MedicationKnowledge.amount has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.amount has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element). This is the quantity of medication in a package. To specify the strength of the medication, the Ingredient.strength attribute is used.

R4: MedicationKnowledge.ingredient (new:BackboneElement)

Element MedicationKnowledge.ingredient has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.ingredient has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.intendedRoute (new:CodeableConcept)

Element MedicationKnowledge.intendedRoute has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.intendedRoute has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.contraindication (new:Reference(DetectedIssue))

Element MedicationKnowledge.contraindication has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.contraindication has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.kinetics (new:BackboneElement)

Element MedicationKnowledge.kinetics has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.kinetics has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

A code to indicate if the medication referred to by this MedicationKnowledge is in active use within the drug database or inventory system. The status refers to the validity about the information of the medication and not to its medicinal properties.

This status is intended to identify if the medication in a local system is in active use within a drug database or inventory. For example, a pharmacy system may create a new drug file record for a compounded product "ABC Hospital Special Cream" with an active status. At some point in the future, it may be determined that the drug record was created with an error and the status is changed to "entered in error". This status is not intended to specify if a medication is part of a particular formulary. It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.

A coded concept defining if the medication is in active use.

R4: MedicationKnowledge.manufacturer (new:Reference(Organization))

Element MedicationKnowledge.manufacturer has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.manufacturer has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.doseForm (new:CodeableConcept)

Element MedicationKnowledge.doseForm has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.doseForm has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element). When Medication is referenced from MedicationRequest, this is the ordered form. When Medication is referenced within MedicationDispense, this is the dispensed form. When Medication is referenced within MedicationAdministration, this is administered form.

R4: MedicationKnowledge.amount (new:Quantity[SimpleQuantity])

Element MedicationKnowledge.amount has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.amount has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element). This is the quantity of medication in a package. To specify the strength of the medication, the Ingredient.strength attribute is used.

R4: MedicationKnowledge.ingredient (new:BackboneElement)

Element MedicationKnowledge.ingredient has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.ingredient has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.intendedRoute (new:CodeableConcept)

Element MedicationKnowledge.intendedRoute has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.intendedRoute has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.contraindication (new:Reference(DetectedIssue))

Element MedicationKnowledge.contraindication has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.contraindication has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.kinetics (new:BackboneElement)

Element MedicationKnowledge.kinetics has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.kinetics has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.status

Element MedicationKnowledge.status is mapped to FHIR R5 element MedicationKnowledge.status as Equivalent. An externally-defined extension that has been mapped as the representation of FHIR R4 element MedicationKnowledge.status: http://hl7.org/fhir/StructureDefinition/artifact-status. This status is intended to identify if the medication in a local system is in active use within a drug database or inventory. For example, a pharmacy system may create a new drug file record for a compounded product "ABC Hospital Special Cream" with an active status. At some point in the future, it may be determined that the drug record was created with an error and the status is changed to "entered in error". This status is not intended to specify if a medication is part of a particular formulary. It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.

R4: MedicationKnowledge.administrationGuidelines.indication[x] (new:CodeableConcept, Reference(ObservationDefinition))

Element MedicationKnowledge.administrationGuidelines.indication[x] has a context of MedicationKnowledge.indicationGuideline based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.administrationGuidelines.indication[x] has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.administrationGuidelines.patientCharacteristics.characteristic[x] (new:CodeableConcept, Quantity[SimpleQuantity])

Element MedicationKnowledge.administrationGuidelines.patientCharacteristics.characteristic[x] has a context of MedicationKnowledge.indicationGuideline.dosingGuideline based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.administrationGuidelines.patientCharacteristics.characteristic[x] has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.administrationGuidelines.patientCharacteristics.value (new:string)

Element MedicationKnowledge.administrationGuidelines.patientCharacteristics.value has a context of MedicationKnowledge.indicationGuideline.dosingGuideline based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.administrationGuidelines.patientCharacteristics.value has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.packaging.type (new:CodeableConcept)

Element MedicationKnowledge.packaging.type has a context of MedicationKnowledge.packaging based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.packaging.type has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.packaging.quantity (new:Quantity[SimpleQuantity])

Element MedicationKnowledge.packaging.quantity has a context of MedicationKnowledge.packaging based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.packaging.quantity has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.regulatory.schedule.schedule (new:CodeableConcept)

Element MedicationKnowledge.regulatory.schedule.schedule has a context of MedicationKnowledge.regulatory.schedule based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.regulatory.schedule.schedule has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.drugCharacteristic.value[x] (new:base64Binary, CodeableConcept, Quantity[SimpleQuantity], string)

Element MedicationKnowledge.drugCharacteristic.value[x] has a context of MedicationKnowledge.definitional based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.drugCharacteristic.value[x] has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element). The description should be provided as a CodeableConcept, SimpleQuantity or an image. The description can be a string only when these others are not available.

Information about a medication that is used to support knowledge.

The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.

Within the context of the FHIR RESTful interactions, the resource has an id except for cases like the create and conditional update. Otherwise, the use of the resouce id depends on the given use case.

The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.

A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.

Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc.

The base language in which the resource is written.

Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).

IETF language tag for a human language

A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.

Contained resources do not have a narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded information is added later.

These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope. This is allowed to be a Parameters resource if and only if it is referenced by a resource that provides context/meaning.

This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags in their meta elements, but SHALL NOT have security labels.

An Extension

R4: MedicationKnowledge.manufacturer (new:Reference(Organization))

Element MedicationKnowledge.manufacturer has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.manufacturer has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.doseForm (new:CodeableConcept)

Element MedicationKnowledge.doseForm has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.doseForm has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element). When Medication is referenced from MedicationRequest, this is the ordered form. When Medication is referenced within MedicationDispense, this is the dispensed form. When Medication is referenced within MedicationAdministration, this is administered form.

R4: MedicationKnowledge.amount (new:Quantity[SimpleQuantity])

Element MedicationKnowledge.amount has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.amount has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element). This is the quantity of medication in a package. To specify the strength of the medication, the Ingredient.strength attribute is used.

R4: MedicationKnowledge.ingredient (new:BackboneElement)

Element MedicationKnowledge.ingredient has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.ingredient has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.intendedRoute (new:CodeableConcept)

Element MedicationKnowledge.intendedRoute has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.intendedRoute has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.contraindication (new:Reference(DetectedIssue))

Element MedicationKnowledge.contraindication has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.contraindication has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.kinetics (new:BackboneElement)

Element MedicationKnowledge.kinetics has a context of MedicationKnowledge based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.kinetics has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

Business identifier for this medication.

This is a business identifier, not a resource identifier (see discussion).

A code that specifies this medication, or a textual description if no code is available. Usage note: This could be a standard medication code such as a code from RxNorm, SNOMED CT, IDMP etc. It could also be a national or local formulary code, optionally with translations to other code systems.

Depending on the context of use, the code that was actually selected by the user (prescriber, dispenser, etc.) will have the coding.userSelected set to true. As described in the coding datatype: "A coding may be marked as a "userSelected" if a user selected the particular coded value in a user interface (e.g. the user selects an item in a pick-list). If a user selected coding exists, it is the preferred choice for performing translations etc. Other codes can only be literal translations to alternative code systems, or codes at a lower level of granularity (e.g. a generic code for a vendor-specific primary one).

A coded concept that defines the type of a medication.

A code to indicate if the medication referred to by this MedicationKnowledge is in active use within the drug database or inventory system. The status refers to the validity about the information of the medication and not to its medicinal properties.

This status is intended to identify if the medication in a local system is in active use within a drug database or inventory. For example, a pharmacy system may create a new drug file record for a compounded product "ABC Hospital Special Cream" with an active status. At some point in the future, it may be determined that the drug record was created with an error and the status is changed to "entered in error". This status is not intended to specify if a medication is part of a particular formulary. It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.

A coded concept defining if the medication is in active use.

unique id for the element within a resource (for internal references)

May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Primitive value for code

The creator or owner of the knowledge or information about the medication.

Lists the jurisdictions that this medication knowledge was written for.

The codes could have varying granularity from a country or group of countries down to a specific district.

All of the names for a medication, for example, the name(s) given to a medication in different countries. For example, acetaminophen and paracetamol or salbutamol and albuterol.

Associated or related medications. For example, if the medication is a branded product (e.g. Crestor), this is the Therapeutic Moeity (e.g. Rosuvastatin) or if this is a generic medication (e.g. Rosuvastatin), this would link to a branded product (e.g. Crestor.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

The category of the associated medication knowledge reference.

Associated documentation about the associated medication knowledge.

Links to associated medications that could be prescribed, dispensed or administered.

Category of the medication or product (e.g. branded product, therapeutic moeity, generic product, innovator product, etc.).

Associated documentation about the medication.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

The category of documentation about the medication. (e.g. professional monograph, patient education monograph).

Associated documentation about the medication.

The instructions for preparing the medication.

The price of the medication.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

The date range for which the cost information of the medication is effective.

The category of the cost information. For example, manufacturers' cost, patient cost, claim reimbursement cost, actual acquisition cost.

The source or owner that assigns the price to the medication.

The price or representation of the cost (for example, Band A, Band B or $, $$) of the medication.

A coded concept defining the category of a medication.

The program under which the medication is reviewed.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

Type of program under which the medication is monitored.

Name of the reviewing program.

Guidelines or protocols that are applicable for the administration of the medication based on indication.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

An Extension

R4: MedicationKnowledge.administrationGuidelines.indication[x] (new:CodeableConcept, Reference(ObservationDefinition))

Element MedicationKnowledge.administrationGuidelines.indication[x] has a context of MedicationKnowledge.indicationGuideline based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.administrationGuidelines.indication[x] has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

Indication or reason for use of the medication that applies to the specific administration guideline.

The guidelines for the dosage of the medication for the indication.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

An Extension

R4: MedicationKnowledge.administrationGuidelines.patientCharacteristics.characteristic[x] (new:CodeableConcept, Quantity[SimpleQuantity])

Element MedicationKnowledge.administrationGuidelines.patientCharacteristics.characteristic[x] has a context of MedicationKnowledge.indicationGuideline.dosingGuideline based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.administrationGuidelines.patientCharacteristics.characteristic[x] has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.administrationGuidelines.patientCharacteristics.value (new:string)

Element MedicationKnowledge.administrationGuidelines.patientCharacteristics.value has a context of MedicationKnowledge.indicationGuideline.dosingGuideline based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.administrationGuidelines.patientCharacteristics.value has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

The overall intention of the treatment, for example, prophylactic, supporative, curative, etc.

Dosage for the medication for the specific guidelines.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

The type or category of dosage for a given medication (for example, prophylaxis, maintenance, therapeutic, etc.).

Dosage for the medication for the specific guidelines.

The type of the treatment that the guideline applies to, for example, long term therapy, first line treatment, etc.

Characteristics of the patient that are relevant to the administration guidelines (for example, height, weight, gender, etc.).

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

The categorization of the specific characteristic that is relevant to the administration guideline (e.g. height, weight, gender).

The specific characteristic (e.g. height, weight, gender, etc.).

Categorization of the medication within a formulary or classification system.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification).

Either a textual source of the classification or a reference to an online source.

Specific category assigned to the medication (e.g. anti-infective, anti-hypertensive, antibiotic, etc.).

Information that only applies to packages (not products).

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

An Extension

R4: MedicationKnowledge.packaging.type (new:CodeableConcept)

Element MedicationKnowledge.packaging.type has a context of MedicationKnowledge.packaging based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.packaging.type has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

R4: MedicationKnowledge.packaging.quantity (new:Quantity[SimpleQuantity])

Element MedicationKnowledge.packaging.quantity has a context of MedicationKnowledge.packaging based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.packaging.quantity has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

The cost of the packaged medication.

A reference to a PackagedProductDefinition that provides the details of the product that is in the packaging and is being priced.

Potential clinical issue with or between medication(s) (for example, drug-drug interaction, drug-disease contraindication, drug-allergy interaction, etc.).

Information on how the medication should be stored, for example, refrigeration temperatures and length of stability at a given temperature.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

Reference to additional information about the storage guidelines.

Additional notes about the storage.

Duration that the medication remains stable if the environmentalSetting is respected.

Describes a setting/value on the environment for the adequate storage of the medication and other substances. Environment settings may involve temperature, humidity, or exposure to light.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

Identifies the category or type of setting (e.g., type of location, temperature, humidity).

Value associated to the setting. E.g., 40° – 50°F for temperature.

Regulatory information about a medication.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

The authority that is specifying the regulations.

Specifies if changes are allowed when dispensing a medication from a regulatory perspective.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

Specifies the type of substitution allowed.

Specifies if regulation allows for changes in the medication when dispensing.

Specifies the schedule of a medication in jurisdiction.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

An Extension

R4: MedicationKnowledge.regulatory.schedule.schedule (new:CodeableConcept)

Element MedicationKnowledge.regulatory.schedule.schedule has a context of MedicationKnowledge.regulatory.schedule based on following the parent source element upwards and mapping to MedicationKnowledge. Element MedicationKnowledge.regulatory.schedule.schedule has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).

A reference to a code defined by a terminology system.

Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.

Allows for alternative encodings within a code system, and translations to other code systems.

A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.

Very often the text is the same as a displayName of one of the codings.

The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.

The maximum number of units of the medication that can be dispensed in a period.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.

Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).

There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.

Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.

The maximum number of units of the medication that can be dispensed.

The period that applies to the maximum number of units.

Along with the link to a Medicinal Product Definition resource, this information provides common definitional elements that are needed to understand the specific medication that is being described.

Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.

An Extension