• Include these codes as defined in http://terminology.hl7.org/CodeSystem/v3-substanceAdminSubstitution version 2018-08-12

  Code	Display	Definition
  BC	brand composition	Substitution occurred or is permitted between equivalent Brands but not Generics *Examples:* * Zestril for Prinivil * Coumadin for Jantoven
  G	generic composition	Substitution occurred or is permitted between equivalent Generics but not Brands *Examples:* * Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)
  EC	equivalent composition	Substitution occurred or is permitted with another product that is a: * pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester * pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration *Examples:* * *Pharmaceutical alternative:* Erythromycin Ethylsuccinate for Erythromycin Stearate * *Pharmaceutical equivalent:* Lisonpril for Zestril
  TB	therapeutic brand	Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics > *Examples:* * Zantac for Tagamet
  TG	therapeutic generic	Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands > *Examples:* * Ranitidine for cimetidine
  TE	therapeutic alternative	Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile. *Examples:* * ranitidine for Tagamet
  E	equivalent	Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.
  F	formulary	This substitution was performed or is permitted based on formulary guidelines.
  N	none	No substitution occurred or is permitted.

This value set expansion contains 9 concepts.