Generated Narrative: StructureDefinition ext-R4-EffectEvidenceSynthesis Name Flags Card. Type Description & Constraints Extension 0..* Extension(4.3.0) A quantified estimate of effect based on a body of evidence #xD; Slices for extension 5..* Extension Extension Slice: Unordered, Closed by value:url #xD; <a href="StructureDefinition-ext-R4-EffectEvidenceSynthesis-definitions.html#Extension.extension:url" title="Slice url: An absolute URI that is used to identify this effect evidence synthesis when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this effect evidence synthesis is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the effect evidence synthesis is stored on different servers.">extension:url 0..1 Extension Canonical identifier for this effect evidence synthesis, represented as a URI (globally unique) #xD; url 1..1 uri "url" #xD; <a href="StructureDefinition-ext-R4-EffectEvidenceSynthesis-definitions.html#Extension.extension:url.value[x]" title="An absolute URI that is used to identify this effect evidence synthesis when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this effect evidence synthesis is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the effect evidence synthesis is stored on different servers.">value[x] 0..1 uri Canonical identifier for this effect evidence synthesis, represented as a URI (globally unique) #xD; <a href="StructureDefinition-ext-R4-EffectEvidenceSynthesis-definitions.html#Extension.extension:version" title="Slice version: The identifier that is used to identify this version of the effect evidence synthesis when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the effect evidence synthesis author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence.">extension:version 0..1 Extension Business version of the effect evidence synthesis #xD; url 1..1 uri "version" #xD; <a href="StructureDefinition-ext-R4-EffectEvidenceSynthesis-definitions.html#Extension.extension:version.value[x]" title="The identifier that is used to identify this version of the effect evidence synthesis when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the effect evidence synthesis author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence.">value[x] 0..1 string Business version of the effect evidence synthesis #xD; extension:name 0..1 Extension Name for this effect evidence synthesis (computer friendly) #xD; url 1..1 uri "name" #xD; value[x] 0..1 string Name for this effect evidence synthesis (computer friendly) #xD; extension:title 0..1 Extension Name for this effect evidence synthesis (human friendly) #xD; url 1..1 uri "title" #xD; value[x] 0..1 string Name for this effect evidence synthesis (human friendly) #xD; extension:status 1..1 Extension draft | active | retired | unknown #xD; url 1..1 uri "status" #xD; value[x] 0..1 code draft | active | retired | unknown Binding: R4_publication_status_for_R4B (0.0.1-snapshot-2) (required): The lifecycle status of an artifact. #xD; <a href="StructureDefinition-ext-R4-EffectEvidenceSynthesis-definitions.html#Extension.extension:date" title="Slice date: The date (and optionally time) when the effect evidence synthesis was published. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the effect evidence synthesis changes.">extension:date 0..1 Extension Date last changed #xD; url 1..1 uri "date" #xD; value[x] 0..1 dateTime Date last changed #xD; extension:publisher 0..1 Extension Name of the publisher (organization or individual) #xD; url 1..1 uri "publisher" #xD; value[x] 0..1 string Name of the publisher (organization or individual) #xD; extension:contact 0..* Extension Contact details for the publisher #xD; url 1..1 uri "contact" #xD; value[x] 0..1 ContactDetail Contact details for the publisher #xD; extension:description 0..1 Extension Natural language description of the effect evidence synthesis #xD; url 1..1 uri "description" #xD; value[x] 0..1 markdown Natural language description of the effect evidence synthesis #xD; extension:note 0..* Extension Used for footnotes or explanatory notes #xD; url 1..1 uri "note" #xD; value[x] 0..1 Annotation Used for footnotes or explanatory notes #xD; <a href="StructureDefinition-ext-R4-EffectEvidenceSynthesis-definitions.html#Extension.extension:useContext" title="Slice useContext: The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate effect evidence synthesis instances.">extension:useContext 0..* Extension The context that the content is intended to support #xD; url 1..1 uri "useContext" #xD; <a href="StructureDefinition-ext-R4-EffectEvidenceSynthesis-definitions.html#Extension.extension:useContext.value[x]" title="The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate effect evidence synthesis instances.">value[x] 0..1 UsageContext The context that the content is intended to support #xD; extension:jurisdiction 0..* Extension Intended jurisdiction for effect evidence synthesis (if applicable) #xD; url 1..1 uri "jurisdiction" #xD; value[x] 0..1 CodeableConcept Intended jurisdiction for effect evidence synthesis (if applicable) Binding: R4_jurisdiction_for_R4B (0.0.1-snapshot-2) (extensible): Countries and regions within which this artifact is targeted for use. #xD; extension:copyright 0..1 Extension Use and/or publishing restrictions #xD; url 1..1 uri "copyright" #xD; value[x] 0..1 markdown Use and/or publishing restrictions #xD; extension:approvalDate 0..1 Extension When the effect evidence synthesis was approved by publisher #xD; url 1..1 uri "approvalDate" #xD; value[x] 0..1 date When the effect evidence synthesis was approved by publisher #xD; extension:lastReviewDate 0..1 Extension When the effect evidence synthesis was last reviewed #xD; url 1..1 uri "lastReviewDate" #xD; value[x] 0..1 date When the effect evidence synthesis was last reviewed #xD; extension:effectivePeriod 0..1 Extension When the effect evidence synthesis is expected to be used #xD; url 1..1 uri "effectivePeriod" #xD; value[x] 0..1 Period When the effect evidence synthesis is expected to be used #xD; extension:topic 0..* Extension The category of the EffectEvidenceSynthesis, such as Education, Treatment, Assessment, etc. #xD; url 1..1 uri "topic" #xD; value[x] 0..1 CodeableConcept The category of the EffectEvidenceSynthesis, such as Education, Treatment, Assessment, etc. Binding: R4_definition_topic_for_R4B (0.0.1-snapshot-2) (example): High-level categorization of the definition, used for searching, sorting, and filtering. #xD; extension:editor 0..* Extension Who edited the content #xD; url 1..1 uri "editor" #xD; value[x] 0..1 ContactDetail Who edited the content #xD; extension:reviewer 0..* Extension Who reviewed the content #xD; url 1..1 uri "reviewer" #xD; value[x] 0..1 ContactDetail Who reviewed the content #xD; extension:endorser 0..* Extension Who endorsed the content #xD; url 1..1 uri "endorser" #xD; value[x] 0..1 ContactDetail Who endorsed the content #xD; extension:relatedArtifact 0..* Extension Additional documentation, citations, etc. #xD; url 1..1 uri "relatedArtifact" #xD; value[x] 0..1 RelatedArtifact Additional documentation, citations, etc. #xD; extension:synthesisType 0..1 Extension Type of synthesis #xD; url 1..1 uri "synthesisType" #xD; value[x] 0..1 CodeableConcept Type of synthesis Binding: SynthesisType (extensible): Types of combining results from a body of evidence (eg. summary data meta-analysis). #xD; extension:studyType 0..1 Extension Type of study #xD; url 1..1 uri "studyType" #xD; value[x] 0..1 CodeableConcept Type of study Binding: R4_study_type_for_R4B (0.0.1-snapshot-2) (extensible): Types of research studies (types of research methods). #xD; extension:population 1..1 Extension What population? #xD; url 1..1 uri "population" #xD; value[x] 0..1 Reference() What population? #xD; extension:exposure 1..1 Extension What exposure? #xD; url 1..1 uri "exposure" #xD; value[x] 0..1 Reference() What exposure? #xD; extension:exposureAlternative 1..1 Extension What comparison exposure? #xD; url 1..1 uri "exposureAlternative" #xD; value[x] 0..1 Reference() What comparison exposure? #xD; extension:outcome 1..1 Extension What outcome? #xD; url 1..1 uri "outcome" #xD; value[x] 0..1 Reference() What outcome? #xD; extension:sampleSize 0..1 Extension What sample size was involved? #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Closed by value:url #xD; extension:description 0..1 Extension Description of sample size #xD; url 1..1 uri "description" #xD; value[x] 0..1 string Description of sample size #xD; extension:numberOfStudies 0..1 Extension How many studies? #xD; url 1..1 uri "numberOfStudies" #xD; value[x] 0..1 integer How many studies? #xD; extension:numberOfParticipants 0..1 Extension How many participants? #xD; url 1..1 uri "numberOfParticipants" #xD; value[x] 0..1 integer How many participants? #xD; url 1..1 uri "sampleSize" #xD; extension:resultsByExposure 0..* Extension What was the result per exposure? #xD; Slices for extension 1..* Extension Extension Slice: Unordered, Closed by value:url #xD; extension:description 0..1 Extension Description of results by exposure #xD; url 1..1 uri "description" #xD; value[x] 0..1 string Description of results by exposure #xD; extension:exposureState 0..1 Extension exposure | exposure-alternative #xD; url 1..1 uri "exposureState" #xD; value[x] 0..1 code exposure | exposure-alternative Binding: R4_exposure_state_for_R4B (0.0.1-snapshot-2) (required): Whether the results by exposure is describing the results for the primary exposure of interest (exposure) or the alternative state (exposureAlternative). #xD; extension:variantState 0..1 Extension Variant exposure states #xD; url 1..1 uri "variantState" #xD; value[x] 0..1 CodeableConcept Variant exposure states Binding: R4_evidence_variant_state_for_R4B (0.0.1-snapshot-2) (extensible): Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states. #xD; extension:riskEvidenceSynthesis 1..1 Extension Risk evidence synthesis #xD; url 1..1 uri "riskEvidenceSynthesis" #xD; value[x] 0..1 Reference() Risk evidence synthesis #xD; url 1..1 uri "resultsByExposure" #xD; extension:effectEstimate 0..* Extension What was the estimated effect #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Closed by value:url #xD; extension:description 0..1 Extension Description of effect estimate #xD; url 1..1 uri "description" #xD; value[x] 0..1 string Description of effect estimate #xD; extension:type 0..1 Extension Type of efffect estimate #xD; url 1..1 uri "type" #xD; value[x] 0..1 CodeableConcept Type of efffect estimate Binding: R4_effect_estimate_type_for_R4B (0.0.1-snapshot-2) (extensible): Whether the effect estimate is an absolute effect estimate (absolute difference) or a relative effect estimate (relative difference), and the specific type of effect estimate (eg relative risk or median difference). #xD; extension:variantState 0..1 Extension Variant exposure states #xD; url 1..1 uri "variantState" #xD; value[x] 0..1 CodeableConcept Variant exposure states Binding: R4_evidence_variant_state_for_R4B (0.0.1-snapshot-2) (extensible): Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states. #xD; extension:value 0..1 Extension Point estimate #xD; url 1..1 uri "value" #xD; value[x] 0..1 decimal Point estimate #xD; extension:unitOfMeasure 0..1 Extension What unit is the outcome described in? #xD; url 1..1 uri "unitOfMeasure" #xD; value[x] 0..1 CodeableConcept What unit is the outcome described in? Binding: UCUMCodes (required): Unified Code for Units of Measure (UCUM). #xD; extension:precisionEstimate 0..* Extension How precise the estimate is #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Closed by value:url #xD; extension:type 0..1 Extension Type of precision estimate #xD; url 1..1 uri "type" #xD; value[x] 0..1 CodeableConcept Type of precision estimate Binding: R4_precision_estimate_type_for_R4B (0.0.1-snapshot-2) (extensible): Method of reporting variability of estimates, such as confidence intervals, interquartile range or standard deviation. #xD; extension:level 0..1 Extension Level of confidence interval #xD; url 1..1 uri "level" #xD; value[x] 0..1 decimal Level of confidence interval #xD; extension:from 0..1 Extension Lower bound #xD; url 1..1 uri "from" #xD; value[x] 0..1 decimal Lower bound #xD; extension:to 0..1 Extension Upper bound #xD; url 1..1 uri "to" #xD; value[x] 0..1 decimal Upper bound #xD; url 1..1 uri "precisionEstimate" #xD; url 1..1 uri "effectEstimate" #xD; extension:certainty 0..* Extension How certain is the effect #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Closed by value:url #xD; extension:rating 0..* Extension Certainty rating #xD; url 1..1 uri "rating" #xD; value[x] 0..1 CodeableConcept Certainty rating Binding: R4_evidence_quality_for_R4B (0.0.1-snapshot-2) (extensible): The quality of the evidence described. The code system used specifies the quality scale used to grade this evidence source while the code specifies the actual quality score (represented as a coded value) associated with the evidence. #xD; extension:note 0..* Extension Used for footnotes or explanatory notes #xD; url 1..1 uri "note" #xD; value[x] 0..1 Annotation Used for footnotes or explanatory notes #xD; extension:certaintySubcomponent 0..* Extension A component that contributes to the overall certainty #xD; Slices for extension 0..* Extension Extension Slice: Unordered, Closed by value:url #xD; extension:type 0..1 Extension Type of subcomponent of certainty rating #xD; url 1..1 uri "type" #xD; value[x] 0..1 CodeableConcept Type of subcomponent of certainty rating Binding: R4_certainty_subcomponent_type_for_R4B (0.0.1-snapshot-2) (extensible): The subcomponent classification of quality of evidence rating systems. #xD; extension:rating 0..* Extension Subcomponent certainty rating #xD; url 1..1 uri "rating" #xD; value[x] 0..1 CodeableConcept Subcomponent certainty rating Binding: R4_certainty_subcomponent_rating_for_R4B (0.0.1-snapshot-2) (extensible): The quality rating of the subcomponent of a quality of evidence rating. #xD; extension:note 0..* Extension Used for footnotes or explanatory notes #xD; url 1..1 uri "note" #xD; value[x] 0..1 Annotation Used for footnotes or explanatory notes #xD; url 1..1 uri "certaintySubcomponent" #xD; url 1..1 uri "certainty" #xD; url 1..1 uri "http://hl7.org/fhir/4.0/StructureDefinition/extension-EffectEvidenceSynthesis" #xD; Documentation for this format
Cross-version Extension for R4.EffectEvidenceSynthesis for use in FHIR R4B
This cross-version extension represents EffectEvidenceSynthesis from http://hl7.org/fhir/StructureDefinition/EffectEvidenceSynthesis|4.0.1 for use in FHIR R4B.
A quantified estimate of effect based on a body of evidence
The EffectEvidenceSynthesis resource describes the difference in an outcome between exposures states in a population where the effect estimate is derived from a combination of research studies.
All FHIR elements must have a @value or children unless an empty Parameters resource
hasValue() or (children().count() > id.count()) or $this is Parameters
Must have either extensions or value[x], not both
exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])
Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Extensions are always sliced by (at least) url
All FHIR elements must have a @value or children
hasValue() or (children().count() > id.count())
exists(f:extension)!=exists(f:*[starts-with(local-name(.), "value")])
Canonical identifier for this effect evidence synthesis, represented as a URI (globally unique)
An absolute URI that is used to identify this effect evidence synthesis when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which at which an authoritative instance of this effect evidence synthesis is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the effect evidence synthesis is stored on different servers.
Additional content defined by implementations
May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Source of the definition for the extension code - a logical name or a URL.
The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.
Business version of the effect evidence synthesis
The identifier that is used to identify this version of the effect evidence synthesis when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the effect evidence synthesis author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence.
Name for this effect evidence synthesis (computer friendly)
A natural language name identifying the effect evidence synthesis. This name should be usable as an identifier for the module by machine processing applications such as code generation.
Name for this effect evidence synthesis (human friendly)
A short, descriptive, user-friendly title for the effect evidence synthesis.
The status of this effect evidence synthesis. Enables tracking the life-cycle of the content.
The date (and optionally time) when the effect evidence synthesis was published. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the effect evidence synthesis changes.
Name of the publisher (organization or individual)
The name of the organization or individual that published the effect evidence synthesis.
Contact details to assist a user in finding and communicating with the publisher.
Natural language description of the effect evidence synthesis
A free text natural language description of the effect evidence synthesis from a consumer's perspective.
A human-readable string to clarify or explain concepts about the resource.
The context that the content is intended to support
The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate effect evidence synthesis instances.
Intended jurisdiction for effect evidence synthesis (if applicable)
A legal or geographic region in which the effect evidence synthesis is intended to be used.
Countries and regions within which this artifact is targeted for use.
A copyright statement relating to the effect evidence synthesis and/or its contents. Copyright statements are generally legal restrictions on the use and publishing of the effect evidence synthesis.
When the effect evidence synthesis was approved by publisher
The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usage.
When the effect evidence synthesis was last reviewed
The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval date.
When the effect evidence synthesis is expected to be used
The period during which the effect evidence synthesis content was or is planned to be in active use.
The category of the EffectEvidenceSynthesis, such as Education, Treatment, Assessment, etc.
Descriptive topics related to the content of the EffectEvidenceSynthesis. Topics provide a high-level categorization grouping types of EffectEvidenceSynthesiss that can be useful for filtering and searching.
High-level categorization of the definition, used for searching, sorting, and filtering.
An individual or organization primarily responsible for internal coherence of the content.
An individual or organization primarily responsible for review of some aspect of the content.
An individual or organization responsible for officially endorsing the content for use in some setting.
Additional documentation, citations, etc.
Related artifacts such as additional documentation, justification, or bibliographic references.
Types of combining results from a body of evidence (eg. summary data meta-analysis).
Types of research studies (types of research methods).
A reference to a EvidenceVariable resource that defines the population for the research.
A reference to a EvidenceVariable resource that defines the exposure for the research.
A reference to a EvidenceVariable resource that defines the comparison exposure for the research.
A reference to a EvidenceVariable resomece that defines the outcome for the research.
A description of the size of the sample involved in the synthesis.
Number of studies included in this evidence synthesis.
Number of participants included in this evidence synthesis.
Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4B/extensibility.html) for a list).
A description of the results for each exposure considered in the effect estimate.
Human-readable summary of results by exposure state.
Whether these results are for the exposure state or alternative exposure state.
Whether the results by exposure is describing the results for the primary exposure of interest (exposure) or the alternative state (exposureAlternative).
Used to define variant exposure states such as low-risk state.
Used for results by exposure in variant states such as low-risk, medium-risk and high-risk states.
Reference to a RiskEvidenceSynthesis resource.
The estimated effect of the exposure variant.
Human-readable summary of effect estimate.
Examples include relative risk and mean difference.
Whether the effect estimate is an absolute effect estimate (absolute difference) or a relative effect estimate (relative difference), and the specific type of effect estimate (eg relative risk or median difference).
The point estimate of the effect estimate.
Specifies the UCUM unit for the outcome.
Unified Code for Units of Measure (UCUM).
A description of the precision of the estimate for the effect.
Examples include confidence interval and interquartile range.
Method of reporting variability of estimates, such as confidence intervals, interquartile range or standard deviation.
A description of the certainty of the effect estimate.
A rating of the certainty of the effect estimate.
The quality of the evidence described. The code system used specifies the quality scale used to grade this evidence source while the code specifies the actual quality score (represented as a coded value) associated with the evidence.
A component that contributes to the overall certainty
A description of a component of the overall certainty.
Type of subcomponent of certainty rating
This cross-version extension represents EffectEvidenceSynthesis.certainty.certaintySubcomponent.type from http://hl7.org/fhir/StructureDefinition/EffectEvidenceSynthesis|4.0.1 for use in FHIR R4B.
The subcomponent classification of quality of evidence rating systems.
A rating of a subcomponent of rating certainty.
The quality rating of the subcomponent of a quality of evidence rating.