• Include these codes as defined in http://hl7.org/fhir/v3/substanceAdminSubstitution version 📍2016-11-11

  Code	Display	Definition
  BC	brand composition	Description: Substitution occurred or is permitted between equivalent Brands but not Generics Examples: Zestril for Prinivil Coumadin for Jantoven
  E	equivalent	Description: Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.
  EC	equivalent composition	Description: Substitution occurred or is permitted with another product that is a: pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration Examples: Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate Pharmaceutical equivalent: Lisonpril for Zestril
  F	formulary	Description: This substitution was performed or is permitted based on formulary guidelines.
  G	generic composition	Description: Substitution occurred or is permitted between equivalent Generics but not Brands Examples: Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)
  N	none	No substitution occurred or is permitted.
  TB	therapeutic brand	Description: Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics > Examples: Zantac for Tagamet
  TE	therapeutic alternative	Description: Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile. Examples: ranitidine for Tagamet
  TG	therapeutic generic	Description: Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands > Examples: Ranitidine for cimetidine
  _ActSubstanceAdminSubstitutionCode	ActSubstanceAdminSubstitutionCode	Description: Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.

This value set expansion contains 10 concepts.

                    Substitution occurred or is permitted between equivalent Brands but not Generics

                    
                       Examples: 
                    

                    
                       Zestril  for Prinivil
                       Coumadin for Jantoven

                    Substitution occurred or is permitted with another product that is a:

                    
                       pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester
                       pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration
                    
                    
                       Examples: 
                    

                    
                       
                          Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate
                       
                          Pharmaceutical equivalent: Lisonpril for Zestril

                       Examples: 
                    

                    
                       Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)

                       Examples: 
                    

                    
                       Zantac for Tagamet

                       Examples: 
                    

                    
                       ranitidine for Tagamet

                       Examples: 
                    

                    
                       Ranitidine  for cimetidine