Extensions for Using Data Elements from FHIR DSTU2 in FHIR R4B
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Extensions for Using Data Elements from FHIR DSTU2 in FHIR R4B - Downloaded Version null See the Directory of published versions

: v3-substanceAdminSubstitution - JSON Representation

Page standards status: Trial-use Maturity Level: 0

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{
  "resourceType" : "CodeSystem",
  "id" : "v3-substanceAdminSubstitution",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: CodeSystem v3-substanceAdminSubstitution</b></p><a name=\"v3-substanceAdminSubstitution\"> </a><a name=\"hcv3-substanceAdminSubstitution\"> </a><p><b>Properties</b></p><p><b>This code system defines the following properties for its concepts</b></p><table class=\"grid\"><tr><td><b>Name</b></td><td><b>Code</b></td><td><b>URI</b></td><td><b>Type</b></td></tr><tr><td>status</td><td>status</td><td>http://hl7.org/fhir/concept-properties#status</td><td>code</td></tr><tr><td>Inactive</td><td>inactive</td><td>http://hl7.org/fhir/concept-properties#inactive</td><td>boolean</td></tr><tr><td>effectiveDate</td><td>effectiveDate</td><td>http://hl7.org/fhir/concept-properties#effectiveDate</td><td>dateTime</td></tr><tr><td>deprecationDate</td><td>deprecationDate</td><td>http://hl7.org/fhir/concept-properties#deprecationDate</td><td>dateTime</td></tr><tr><td>retirementDate</td><td>retirementDate</td><td>http://hl7.org/fhir/concept-properties#retirementDate</td><td>dateTime</td></tr><tr><td>Not Selectable</td><td>notSelectable</td><td>http://hl7.org/fhir/concept-properties#notSelectable</td><td>boolean</td></tr><tr><td>Parent</td><td>parent</td><td>http://hl7.org/fhir/concept-properties#parent</td><td>code</td></tr><tr><td>Child</td><td>child</td><td>http://hl7.org/fhir/concept-properties#child</td><td>code</td></tr><tr><td>partOf</td><td>partOf</td><td>http://hl7.org/fhir/concept-properties#partOf</td><td>code</td></tr><tr><td>synonym</td><td>synonym</td><td>http://hl7.org/fhir/concept-properties#synonym</td><td>code</td></tr><tr><td>comment</td><td>comment</td><td>http://hl7.org/fhir/concept-properties#comment</td><td>string</td></tr><tr><td>itemWeight</td><td>itemWeight</td><td>http://hl7.org/fhir/concept-properties#itemWeight</td><td>decimal</td></tr></table><p><b>Concepts</b></p><p>This case-sensitive code system <code>http://hl7.org/fhir/v3/substanceAdminSubstitution</code> defines the following codes in an undefined hierarchy:</p><table class=\"codes\"><tr><td><b>Lvl</b></td><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td><td><b>Not Selectable</b></td></tr><tr><td>1</td><td style=\"white-space:nowrap\">_ActSubstanceAdminSubstitutionCode<a name=\"v3-substanceAdminSubstitution-_ActSubstanceAdminSubstitutionCode\"> </a></td><td>ActSubstanceAdminSubstitutionCode</td><td>Description: Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.</td><td>true</td></tr><tr><td>2</td><td style=\"white-space:nowrap\">\u00a0\u00a0E<a name=\"v3-substanceAdminSubstitution-E\"> </a></td><td>equivalent</td><td>Description: Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.</td><td>false</td></tr><tr><td>3</td><td style=\"white-space:nowrap\">\u00a0\u00a0\u00a0\u00a0EC<a name=\"v3-substanceAdminSubstitution-EC\"> </a></td><td>equivalent composition</td><td>Description:                                                    Substitution occurred or is permitted with another product that is a:                                                      pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester                            pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration                                                                              Examples:                                                                                                               Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate                                                           Pharmaceutical equivalent: Lisonpril for Zestril</td><td>false</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0BC<a name=\"v3-substanceAdminSubstitution-BC\"> </a></td><td>brand composition</td><td>Description:                                                    Substitution occurred or is permitted between equivalent Brands but not Generics                                                      Examples:                                                                                Zestril  for Prinivil                            Coumadin for Jantoven</td><td>false</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0G<a name=\"v3-substanceAdminSubstitution-G\"> </a></td><td>generic composition</td><td>Description: Substitution occurred or is permitted between equivalent Generics but not Brands                                                      Examples:                                                                                Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)</td><td>false</td></tr><tr><td>3</td><td style=\"white-space:nowrap\">\u00a0\u00a0\u00a0\u00a0TE<a name=\"v3-substanceAdminSubstitution-TE\"> </a></td><td>therapeutic alternative</td><td>Description: Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.                                                      Examples:                                                                                ranitidine for Tagamet</td><td>false</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0TB<a name=\"v3-substanceAdminSubstitution-TB\"> </a></td><td>therapeutic brand</td><td>Description: Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics &gt;                            Examples:                                                                                Zantac for Tagamet</td><td>false</td></tr><tr><td>4</td><td style=\"white-space:nowrap\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0TG<a name=\"v3-substanceAdminSubstitution-TG\"> </a></td><td>therapeutic generic</td><td>Description: Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands &gt;                            Examples:                                                                                Ranitidine  for cimetidine</td><td>false</td></tr><tr><td>2</td><td style=\"white-space:nowrap\">\u00a0\u00a0F<a name=\"v3-substanceAdminSubstitution-F\"> </a></td><td>formulary</td><td>Description: This substitution was performed or is permitted based on formulary guidelines.</td><td>false</td></tr><tr><td>2</td><td style=\"white-space:nowrap\">\u00a0\u00a0N<a name=\"v3-substanceAdminSubstitution-N\"> </a></td><td>none</td><td>No substitution occurred or is permitted.</td><td>false</td></tr></table></div>"
  },
  "extension" : [
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/valueset-oid",
      "valueUri" : "urn:oid:2.16.840.1.113883.5.1070"
    },
    {
      "extension" : [
        {
          "url" : "packageId",
          "valueId" : "hl7.fhir.uv.xver-r2.r4b"
        },
        {
          "url" : "version",
          "valueString" : "0.1.0"
        },
        {
          "url" : "uri",
          "valueUri" : "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r2.r4b"
        }
      ],
      "url" : "http://hl7.org/fhir/StructureDefinition/package-source"
    },
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode" : "fhir"
    },
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
      "valueInteger" : 0,
      "_valueInteger" : {
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
            "valueCanonical" : "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r2.r4b"
          }
        ]
      }
    },
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
      "valueCode" : "trial-use",
      "_valueCode" : {
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
            "valueCanonical" : "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r2.r4b"
          }
        ]
      }
    }
  ],
  "url" : "http://hl7.org/fhir/v3/substanceAdminSubstitution",
  "version" : "1.0.2",
  "name" : "v3-substanceAdminSubstitution",
  "status" : "draft",
  "date" : "2026-03-20T11:13:27+11:00",
  "publisher" : "FHIR Infrastructure",
  "contact" : [
    {
      "name" : "FHIR Infrastructure",
      "telecom" : [
        {
          "system" : "url",
          "value" : "http://www.hl7.org/Special/committees/fiwg"
        }
      ]
    }
  ],
  "jurisdiction" : [
    {
      "coding" : [
        {
          "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code" : "001",
          "display" : "World"
        }
      ]
    }
  ],
  "caseSensitive" : true,
  "content" : "complete",
  "property" : [
    {
      "code" : "status",
      "uri" : "http://hl7.org/fhir/concept-properties#status",
      "type" : "code"
    },
    {
      "code" : "inactive",
      "uri" : "http://hl7.org/fhir/concept-properties#inactive",
      "type" : "boolean"
    },
    {
      "code" : "effectiveDate",
      "uri" : "http://hl7.org/fhir/concept-properties#effectiveDate",
      "type" : "dateTime"
    },
    {
      "code" : "deprecationDate",
      "uri" : "http://hl7.org/fhir/concept-properties#deprecationDate",
      "type" : "dateTime"
    },
    {
      "code" : "retirementDate",
      "uri" : "http://hl7.org/fhir/concept-properties#retirementDate",
      "type" : "dateTime"
    },
    {
      "code" : "notSelectable",
      "uri" : "http://hl7.org/fhir/concept-properties#notSelectable",
      "type" : "boolean"
    },
    {
      "code" : "parent",
      "uri" : "http://hl7.org/fhir/concept-properties#parent",
      "type" : "code"
    },
    {
      "code" : "child",
      "uri" : "http://hl7.org/fhir/concept-properties#child",
      "type" : "code"
    },
    {
      "code" : "partOf",
      "uri" : "http://hl7.org/fhir/concept-properties#partOf",
      "type" : "code"
    },
    {
      "code" : "synonym",
      "uri" : "http://hl7.org/fhir/concept-properties#synonym",
      "type" : "code"
    },
    {
      "code" : "comment",
      "uri" : "http://hl7.org/fhir/concept-properties#comment",
      "type" : "string"
    },
    {
      "code" : "itemWeight",
      "uri" : "http://hl7.org/fhir/concept-properties#itemWeight",
      "type" : "decimal"
    }
  ],
  "concept" : [
    {
      "code" : "_ActSubstanceAdminSubstitutionCode",
      "display" : "ActSubstanceAdminSubstitutionCode",
      "definition" : "Description: Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.",
      "property" : [
        {
          "code" : "notSelectable",
          "valueBoolean" : true
        }
      ],
      "concept" : [
        {
          "code" : "E",
          "display" : "equivalent",
          "definition" : "Description: Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.",
          "property" : [
            {
              "code" : "notSelectable",
              "valueBoolean" : false
            }
          ],
          "concept" : [
            {
              "code" : "EC",
              "display" : "equivalent composition",
              "definition" : "Description:                                                    Substitution occurred or is permitted with another product that is a:                                                      pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester                            pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration                                                                              Examples:                                                                                                               Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate                                                           Pharmaceutical equivalent: Lisonpril for Zestril",
              "property" : [
                {
                  "code" : "notSelectable",
                  "valueBoolean" : false
                }
              ],
              "concept" : [
                {
                  "code" : "BC",
                  "display" : "brand composition",
                  "definition" : "Description:                                                    Substitution occurred or is permitted between equivalent Brands but not Generics                                                      Examples:                                                                                Zestril  for Prinivil                            Coumadin for Jantoven",
                  "property" : [
                    {
                      "code" : "notSelectable",
                      "valueBoolean" : false
                    }
                  ]
                },
                {
                  "code" : "G",
                  "display" : "generic composition",
                  "definition" : "Description: Substitution occurred or is permitted between equivalent Generics but not Brands                                                      Examples:                                                                                Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)",
                  "property" : [
                    {
                      "code" : "notSelectable",
                      "valueBoolean" : false
                    }
                  ]
                }
              ]
            },
            {
              "code" : "TE",
              "display" : "therapeutic alternative",
              "definition" : "Description: Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile.                                                      Examples:                                                                                ranitidine for Tagamet",
              "property" : [
                {
                  "code" : "notSelectable",
                  "valueBoolean" : false
                }
              ],
              "concept" : [
                {
                  "code" : "TB",
                  "display" : "therapeutic brand",
                  "definition" : "Description: Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics >                            Examples:                                                                                Zantac for Tagamet",
                  "property" : [
                    {
                      "code" : "notSelectable",
                      "valueBoolean" : false
                    }
                  ]
                },
                {
                  "code" : "TG",
                  "display" : "therapeutic generic",
                  "definition" : "Description: Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands >                            Examples:                                                                                Ranitidine  for cimetidine",
                  "property" : [
                    {
                      "code" : "notSelectable",
                      "valueBoolean" : false
                    }
                  ]
                }
              ]
            }
          ]
        },
        {
          "code" : "F",
          "display" : "formulary",
          "definition" : "Description: This substitution was performed or is permitted based on formulary guidelines.",
          "property" : [
            {
              "code" : "notSelectable",
              "valueBoolean" : false
            }
          ]
        },
        {
          "code" : "N",
          "display" : "none",
          "definition" : "No substitution occurred or is permitted.",
          "property" : [
            {
              "code" : "notSelectable",
              "valueBoolean" : false
            }
          ]
        }
      ]
    }
  ]
}