{ "resourceType" : "CodeSystem", "id" : "v3-substanceAdminSubstitution", "text" : { "status" : "generated", "div" : "

Generated Narrative: CodeSystem v3-substanceAdminSubstitution

Properties

This code system defines the following properties for its concepts

NameCodeURIType
statusstatushttp://hl7.org/fhir/concept-properties#statuscode
Inactiveinactivehttp://hl7.org/fhir/concept-properties#inactiveboolean
effectiveDateeffectiveDatehttp://hl7.org/fhir/concept-properties#effectiveDatedateTime
deprecationDatedeprecationDatehttp://hl7.org/fhir/concept-properties#deprecationDatedateTime
retirementDateretirementDatehttp://hl7.org/fhir/concept-properties#retirementDatedateTime
Not SelectablenotSelectablehttp://hl7.org/fhir/concept-properties#notSelectableboolean
Parentparenthttp://hl7.org/fhir/concept-properties#parentcode
Childchildhttp://hl7.org/fhir/concept-properties#childcode
partOfpartOfhttp://hl7.org/fhir/concept-properties#partOfcode
synonymsynonymhttp://hl7.org/fhir/concept-properties#synonymcode
commentcommenthttp://hl7.org/fhir/concept-properties#commentstring
itemWeightitemWeighthttp://hl7.org/fhir/concept-properties#itemWeightdecimal

Concepts

This case-sensitive code system http://hl7.org/fhir/v3/substanceAdminSubstitution defines the following codes in an undefined hierarchy:

LvlCodeDisplayDefinitionNot Selectable
1_ActSubstanceAdminSubstitutionCode ActSubstanceAdminSubstitutionCodeDescription: Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.true
2\u00a0\u00a0E equivalentDescription: Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.false
3\u00a0\u00a0\u00a0\u00a0EC equivalent compositionDescription: Substitution occurred or is permitted with another product that is a: pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration Examples: Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate Pharmaceutical equivalent: Lisonpril for Zestrilfalse
4\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0BC brand compositionDescription: Substitution occurred or is permitted between equivalent Brands but not Generics Examples: Zestril for Prinivil Coumadin for Jantovenfalse
4\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0G generic compositionDescription: Substitution occurred or is permitted between equivalent Generics but not Brands Examples: Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)false
3\u00a0\u00a0\u00a0\u00a0TE therapeutic alternativeDescription: Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile. Examples: ranitidine for Tagametfalse
4\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0TB therapeutic brandDescription: Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics > Examples: Zantac for Tagametfalse
4\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0TG therapeutic genericDescription: Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands > Examples: Ranitidine for cimetidinefalse
2\u00a0\u00a0F formularyDescription: This substitution was performed or is permitted based on formulary guidelines.false
2\u00a0\u00a0N noneNo substitution occurred or is permitted.false
" }, "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/valueset-oid", "valueUri" : "urn:oid:2.16.840.1.113883.5.1070" }, { "extension" : [{ "url" : "packageId", "valueId" : "hl7.fhir.uv.xver-r2.r4" }, { "url" : "version", "valueString" : "0.0.1-snapshot-2" }], "url" : "http://hl7.org/fhir/StructureDefinition/package-source" }, { "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg", "valueCode" : "fhir" }, { "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm", "valueInteger" : 0, "_valueInteger" : { "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom", "valueCanonical" : "http://hl7.org/fhir/1.0/ImplementationGuide/hl7.fhir.uv.xver-r2.r4" }] } }, { "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status", "valueCode" : "trial-use", "_valueCode" : { "extension" : [{ "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom", "valueCanonical" : "http://hl7.org/fhir/1.0/ImplementationGuide/hl7.fhir.uv.xver-r2.r4" }] } }], "url" : "http://hl7.org/fhir/v3/substanceAdminSubstitution", "version" : "1.0.2", "name" : "v3-substanceAdminSubstitution", "status" : "draft", "date" : "2025-09-13T15:01:03-04:00", "publisher" : "FHIR Infrastructure", "contact" : [{ "name" : "FHIR Infrastructure", "telecom" : [{ "system" : "url", "value" : "http://www.hl7.org/Special/committees/fiwg" }] }], "jurisdiction" : [{ "coding" : [{ "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm", "code" : "001", "display" : "World" }] }], "caseSensitive" : true, "content" : "complete", "property" : [{ "code" : "status", "uri" : "http://hl7.org/fhir/concept-properties#status", "type" : "code" }, { "code" : "inactive", "uri" : "http://hl7.org/fhir/concept-properties#inactive", "type" : "boolean" }, { "code" : "effectiveDate", "uri" : "http://hl7.org/fhir/concept-properties#effectiveDate", "type" : "dateTime" }, { "code" : "deprecationDate", "uri" : "http://hl7.org/fhir/concept-properties#deprecationDate", "type" : "dateTime" }, { "code" : "retirementDate", "uri" : "http://hl7.org/fhir/concept-properties#retirementDate", "type" : "dateTime" }, { "code" : "notSelectable", "uri" : "http://hl7.org/fhir/concept-properties#notSelectable", "type" : "boolean" }, { "code" : "parent", "uri" : "http://hl7.org/fhir/concept-properties#parent", "type" : "code" }, { "code" : "child", "uri" : "http://hl7.org/fhir/concept-properties#child", "type" : "code" }, { "code" : "partOf", "uri" : "http://hl7.org/fhir/concept-properties#partOf", "type" : "code" }, { "code" : "synonym", "uri" : "http://hl7.org/fhir/concept-properties#synonym", "type" : "code" }, { "code" : "comment", "uri" : "http://hl7.org/fhir/concept-properties#comment", "type" : "string" }, { "code" : "itemWeight", "uri" : "http://hl7.org/fhir/concept-properties#itemWeight", "type" : "decimal" }], "concept" : [{ "code" : "_ActSubstanceAdminSubstitutionCode", "display" : "ActSubstanceAdminSubstitutionCode", "definition" : "Description: Substitution occurred or is permitted with another product that may potentially have different ingredients, but having the same biological and therapeutic effects.", "property" : [{ "code" : "notSelectable", "valueBoolean" : true }], "concept" : [{ "code" : "E", "display" : "equivalent", "definition" : "Description: Substitution occurred or is permitted with another bioequivalent and therapeutically equivalent product.", "property" : [{ "code" : "notSelectable", "valueBoolean" : false }], "concept" : [{ "code" : "EC", "display" : "equivalent composition", "definition" : "Description: Substitution occurred or is permitted with another product that is a: pharmaceutical alternative containing the same active ingredient but is formulated with different salt, ester pharmaceutical equivalent that has the same active ingredient, strength, dosage form and route of administration Examples: Pharmaceutical alternative: Erythromycin Ethylsuccinate for Erythromycin Stearate Pharmaceutical equivalent: Lisonpril for Zestril", "property" : [{ "code" : "notSelectable", "valueBoolean" : false }], "concept" : [{ "code" : "BC", "display" : "brand composition", "definition" : "Description: Substitution occurred or is permitted between equivalent Brands but not Generics Examples: Zestril for Prinivil Coumadin for Jantoven", "property" : [{ "code" : "notSelectable", "valueBoolean" : false }] }, { "code" : "G", "display" : "generic composition", "definition" : "Description: Substitution occurred or is permitted between equivalent Generics but not Brands Examples: Lisnopril (Lupin Corp) for Lisnopril (Wockhardt Corp)", "property" : [{ "code" : "notSelectable", "valueBoolean" : false }] }] }, { "code" : "TE", "display" : "therapeutic alternative", "definition" : "Description: Substitution occurred or is permitted with another product having the same therapeutic objective and safety profile. Examples: ranitidine for Tagamet", "property" : [{ "code" : "notSelectable", "valueBoolean" : false }], "concept" : [{ "code" : "TB", "display" : "therapeutic brand", "definition" : "Description: Substitution occurred or is permitted between therapeutically equivalent Brands but not Generics > Examples: Zantac for Tagamet", "property" : [{ "code" : "notSelectable", "valueBoolean" : false }] }, { "code" : "TG", "display" : "therapeutic generic", "definition" : "Description: Substitution occurred or is permitted between therapeutically equivalent Generics but not Brands > Examples: Ranitidine for cimetidine", "property" : [{ "code" : "notSelectable", "valueBoolean" : false }] }] }] }, { "code" : "F", "display" : "formulary", "definition" : "Description: This substitution was performed or is permitted based on formulary guidelines.", "property" : [{ "code" : "notSelectable", "valueBoolean" : false }] }, { "code" : "N", "display" : "none", "definition" : "No substitution occurred or is permitted.", "property" : [{ "code" : "notSelectable", "valueBoolean" : false }] }] }] }