Order Catalog Implementation Guide
1.0.0 - STU 1

Order Catalog Implementation Guide - Local Development build (v1.0.0) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

## : Clarithromycin oral antibacterial - JSON Representation

Page standards status: Informative

Raw json | Download

    {
      "resourceType" : "MedicationKnowledge",
      "id" : "example-drug-clarithromycin-25mg-granule-suspension",
      "meta" : {
        "profile" : [
          🔗 "http://hl7.org/fhir/uv/order-catalog/StructureDefinition/DrugKnowledge"
        ]
      },
      "language" : "en-US",
      "text" : {
        "status" : "extensions",
        "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\" xml:lang=\"en-US\" lang=\"en-US\"><p class=\"res-header-id\"><b>Generated Narrative: MedicationKnowledge example-drug-clarithromycin-25mg-granule-suspension</b></p><a name=\"example-drug-clarithromycin-25mg-granule-suspension\"> </a><a name=\"hcexample-drug-clarithromycin-25mg-granule-suspension\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Language: en-US</p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-DrugKnowledge.html\">item in a catalog of drugs</a></p></div><p><b>Reference to a catalog</b>: <a href=\"Composition-example-medication-catalog-header.html\">Composition Drugs authorized for prescription in Healthyland</a></p><p><b>code</b>: <span title=\"Codes:{http://snomed.info/sct 769316002}\">Clarithromycin 25 mg/mL oral suspension</span></p><p><b>intendedJurisdiction</b>: <span title=\"Codes:\">Healthyland</span></p><p><b>name</b>: CLARITHROMYCINE GENERIC-LAB 25 mg/ml, granules for oral suspension</p><p><b>productType</b>: <span title=\"Codes:\">Generic product</span></p><blockquote><p><b>indicationGuideline</b></p><h3>Indications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Reference</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"ClinicalUseDefinition-example-bacterial-pharyngitis-indication.html\">ClinicalUseDefinition: type = indication</a></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"ClinicalUseDefinition-example-acute-otitis-media-indication.html\">ClinicalUseDefinition: type = indication</a></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"ClinicalUseDefinition-example-bacterial-sinusitis-indication.html\">ClinicalUseDefinition: type = indication</a></td></tr></table><blockquote><p><b>dosingGuideline</b></p><h3>PatientCharacteristics</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://loinc.org 30525-0}\">Age</span></td><td>0.5-12 years</td></tr></table></blockquote></blockquote><blockquote><p><b>medicineClassification</b></p><p><b>type</b>: <span title=\"Codes:\">Anatomical Therapeutic Chemical (ATC)</span></p><p><b>source</b>: <a href=\"https://www.whocc.no/atc/structure_and_principles/\">https://www.whocc.no/atc/structure_and_principles/</a></p><p><b>classification</b>: <span title=\"Codes:{http://www.whocc.no/atc J01FA09}\">Clarithromycin</span></p></blockquote><blockquote><p><b>medicineClassification</b></p><p><b>type</b>: <span title=\"Codes:\">SNOMED CT drug dispositions</span></p><p><b>source</b>: <a href=\"https://confluence.ihtsdotools.org/display/DOCEG/SNOMED+CT+Editorial+Guide+-+Pharmaceutical+and+Biologic+Product\">https://confluence.ihtsdotools.org/display/DOCEG/SNOMED+CT+Editorial+Guide+-+Pharmaceutical+and+Biologic+Product</a></p><p><b>classification</b>: <span title=\"Codes:{http://snomed.info/sct 419241000}\">Substance with antibacterial mechanism of action (substance)</span></p></blockquote><blockquote><p><b>packaging</b></p><h3>Costs</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>EffectiveDate</b></td><td><b>Type</b></td><td><b>Source</b></td><td><b>Cost[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>2021-02-01 --&gt; (ongoing)</td><td><span title=\"Codes:\">public price</span></td><td>Healthyland Drug Administration</td><td><span title=\"Euro\">€5.18</span> (EUR)</td></tr><tr><td style=\"display: none\">*</td><td>2020-09-30 --&gt; 2021-01-31</td><td><span title=\"Codes:\">public price</span></td><td>Healthyland Drug Administration</td><td><span title=\"Euro\">€5.20</span> (EUR)</td></tr><tr><td style=\"display: none\">*</td><td>2010-03-01 --&gt; (ongoing)</td><td><span title=\"Codes:\">manufacturers' cost</span></td><td>Healthyland Drug Administration</td><td><span title=\"Euro\">€4.40</span> (EUR)</td></tr></table><p><b>packagedProduct</b>: <a href=\"PackagedProductDefinition-example-drug-package-clarithromycin.html\">PackagedProductDefinition Package for CLARITHROMYCINE GENERIC-LAB 25 mg/ml, granules for oral suspension in 100 ml HDPE bottle</a></p></blockquote><p><b>clinicalUseIssue</b>: <a href=\"ClinicalUseDefinition-example-allergy-contraindication.html\">ClinicalUseDefinition: type = contraindication</a></p><blockquote><p><b>definitional</b></p><p><b>doseForm</b>: <span title=\"Codes:{http://snomed.info/sct 385029002}, {http://standardterms.edqm.eu 10113000}\">Granules for oral suspension</span></p><p><b>intendedRoute</b>: <span title=\"Codes:{http://snomed.info/sct 26643006}\">Oral route</span></p><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 387487009}\">Clarithromycin</span></td></tr></table><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-RoleClass ACTIB}\">active ingredient - basis of strength</span></p><p><b>strength</b>: 25 milligram<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemg = 'mg')</span>/1 milliliter<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM  codemL = 'mL')</span></p></blockquote><blockquote><p><b>ingredient</b></p><h3>Items</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Concept</b></td></tr><tr><td style=\"display: none\">*</td><td><span title=\"Codes:{http://snomed.info/sct 11320009}\">Sucrose</span></td></tr></table><p><b>type</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/v3-RoleClass IACT}\">inactive ingredient</span></p></blockquote></blockquote></div>"
      },
      "extension" : [
        {
          "url" : "http://hl7.org/fhir/uv/order-catalog/StructureDefinition/CatalogReference",
          "valueReference" : {
            🔗 "reference" : "Composition/example-medication-catalog-header"
          }
        }
      ],
      "code" : {
        "coding" : [
          {
            "system" : "http://snomed.info/sct",
            "code" : "769316002",
            "display" : "Clarithromycin 25 mg/mL oral suspension"
          }
        ]
      },
      "intendedJurisdiction" : [
        {
          "text" : "Healthyland"
        }
      ],
      "name" : [
        "CLARITHROMYCINE GENERIC-LAB 25 mg/ml, granules for oral suspension"
      ],
      "productType" : [
        {
          "text" : "Generic product"
        }
      ],
      "indicationGuideline" : [
        {
          "indication" : [
            {
              "reference" : {
                🔗 "reference" : "ClinicalUseDefinition/example-bacterial-pharyngitis-indication"
              }
            },
            {
              "reference" : {
                🔗 "reference" : "ClinicalUseDefinition/example-acute-otitis-media-indication"
              }
            },
            {
              "reference" : {
                🔗 "reference" : "ClinicalUseDefinition/example-bacterial-sinusitis-indication"
              }
            }
          ],
          "dosingGuideline" : [
            {
              "patientCharacteristic" : [
                {
                  "type" : {
                    "coding" : [
                      {
                        "system" : "http://loinc.org",
                        "code" : "30525-0",
                        "display" : "Age"
                      }
                    ]
                  },
                  "valueRange" : {
                    "low" : {
                      "value" : 0.5,
                      "unit" : "years",
                      "system" : "http://unitsofmeasure.org",
                      "code" : "a"
                    },
                    "high" : {
                      "value" : 12,
                      "unit" : "years",
                      "system" : "http://unitsofmeasure.org",
                      "code" : "a"
                    }
                  }
                }
              ]
            }
          ]
        }
      ],
      "medicineClassification" : [
        {
          "type" : {
            "text" : "Anatomical Therapeutic Chemical (ATC)"
          },
          "sourceUri" : "https://www.whocc.no/atc/structure_and_principles/",
          "classification" : [
            {
              "coding" : [
                {
                  "system" : "http://www.whocc.no/atc",
                  "code" : "J01FA09",
                  "display" : "Clarithromycin"
                }
              ]
            }
          ]
        },
        {
          "type" : {
            "text" : "SNOMED CT drug dispositions"
          },
          "sourceUri" : "https://confluence.ihtsdotools.org/display/DOCEG/SNOMED+CT+Editorial+Guide+-+Pharmaceutical+and+Biologic+Product",
          "classification" : [
            {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "419241000",
                  "display" : "Substance with antibacterial mechanism of action (substance)"
                }
              ]
            }
          ]
        }
      ],
      "packaging" : [
        {
          "cost" : [
            {
              "effectiveDate" : [
                {
                  "start" : "2021-02-01"
                }
              ],
              "type" : {
                "text" : "public price"
              },
              "source" : "Healthyland Drug Administration",
              "costMoney" : {
                "value" : 5.18,
                "currency" : "EUR"
              }
            },
            {
              "effectiveDate" : [
                {
                  "start" : "2020-09-30",
                  "end" : "2021-01-31"
                }
              ],
              "type" : {
                "text" : "public price"
              },
              "source" : "Healthyland Drug Administration",
              "costMoney" : {
                "value" : 5.2,
                "currency" : "EUR"
              }
            },
            {
              "effectiveDate" : [
                {
                  "start" : "2010-03-01"
                }
              ],
              "type" : {
                "text" : "manufacturers' cost"
              },
              "source" : "Healthyland Drug Administration",
              "costMoney" : {
                "value" : 4.4,
                "currency" : "EUR"
              }
            }
          ],
          "packagedProduct" : {
            🔗 "reference" : "PackagedProductDefinition/example-drug-package-clarithromycin"
          }
        }
      ],
      "clinicalUseIssue" : [
        {
          🔗 "reference" : "ClinicalUseDefinition/example-allergy-contraindication"
        }
      ],
      "definitional" : {
        "doseForm" : {
          "coding" : [
            {
              "system" : "http://snomed.info/sct",
              "code" : "385029002",
              "display" : "Granules for oral suspension"
            },
            {
              "system" : "http://standardterms.edqm.eu",
              "code" : "10113000",
              "display" : "Granules for oral suspension"
            }
          ]
        },
        "intendedRoute" : [
          {
            "coding" : [
              {
                "system" : "http://snomed.info/sct",
                "code" : "26643006",
                "display" : "Oral route"
              }
            ]
          }
        ],
        "ingredient" : [
          {
            "item" : {
              "concept" : {
                "coding" : [
                  {
                    "system" : "http://snomed.info/sct",
                    "code" : "387487009",
                    "display" : "Clarithromycin"
                  }
                ]
              }
            },
            "type" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/v3-RoleClass",
                  "code" : "ACTIB",
                  "display" : "active ingredient - basis of strength"
                }
              ]
            },
            "strengthRatio" : {
              "numerator" : {
                "value" : 25,
                "unit" : "milligram",
                "system" : "http://unitsofmeasure.org",
                "code" : "mg"
              },
              "denominator" : {
                "value" : 1,
                "unit" : "milliliter",
                "system" : "http://unitsofmeasure.org",
                "code" : "mL"
              }
            }
          },
          {
            "item" : {
              "concept" : {
                "coding" : [
                  {
                    "system" : "http://snomed.info/sct",
                    "code" : "11320009",
                    "display" : "Sucrose"
                  }
                ]
              }
            },
            "type" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/v3-RoleClass",
                  "code" : "IACT",
                  "display" : "inactive ingredient"
                }
              ]
            }
          }
        ]
      }
    }