{
  "resourceType": "ValueSet",
  "id": "high-low-codes-vs",
  "text": {
    "status": "extensions",
    "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><ul><li>Include these codes as defined in <a href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-ObservationInterpretation.html\"><code>http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation</code></a><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td><a href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-ObservationInterpretation.html#v3-ObservationInterpretation-H\">H</a></td><td>High</td><td>The result for a quantitative observation is above the upper limit of the reference range (as defined for the respective test procedure).<br/><br/>Synonym: Above high normal</td></tr><tr><td><a href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-ObservationInterpretation.html#v3-ObservationInterpretation-L\">L</a></td><td>Low</td><td>The result for a quantitative observation is below the lower limit of the reference range (as defined for the respective test procedure).<br/><br/>Synonym: Below low normal</td></tr><tr><td><a href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-ObservationInterpretation.html#v3-ObservationInterpretation-I\">I</a></td><td>Intermediate</td><td>Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with uncertain therapeutic effect. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2<br/><br/>\\[Note 1: Bacterial strains are categorized as intermediate by applying the appropriate breakpoints in a defined phenotypic test system.\\]<br/><br/>\\[Note 2: This class of susceptibility implies that an infection due to the isolate can be appropriately treated in body sites where the drugs are physiologically concentrated or when a high dosage of drug can be used.\\]<br/><br/>\\[Note 3: This class also indicates a &quot;buffer zone,&quot; to prevent small, uncontrolled, technical factors from causing major discrepancies in interpretations.\\]<br/><br/>\\[Note 4: These breakpoints can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]</td></tr></table></li></ul></div>"
  },
  "url": "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/high-low-codes-vs",
  "version": "2.0.0",
  "name": "HighLowCodesVS",
  "title": "High Low codes",
  "status": "active",
  "date": "2022-05-09T16:59:16+00:00",
  "publisher": "HL7 Clinical Genomics Working Group",
  "contact": [
    {
      "name": "HL7 Clinical Genomics Working Group",
      "telecom": [
        {
          "system": "url",
          "value": "http://www.hl7.org/Special/committees/clingenomics"
        },
        {
          "system": "email",
          "value": "cg@lists.HL7.org"
        }
      ]
    }
  ],
  "description": "This value set includes high/low codes for Observation Interpretations",
  "jurisdiction": [
    {
      "coding": [
        {
          "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code": "001",
          "display": "World"
        }
      ]
    }
  ],
  "compose": {
    "include": [
      {
        "system": "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "concept": [
          {
            "code": "H",
            "display": "High"
          },
          {
            "code": "L",
            "display": "Low"
          },
          {
            "code": "I",
            "display": "Intermediate"
          }
        ]
      }
    ]
  }
}