Genomics Reporting Implementation Guide
2.0.0 - trial-use

This page is part of the Genetic Reporting Implementation Guide (v2.0.0: STU 2) based on FHIR R4. This is the current published version. For a full list of available versions, see the Directory of published versions

Example Task: PGxRecEx01

Generated Narrative

Resource "PGxRecEx01"

Profile: Followup Recommendation

status: requested

intent: proposal

code: Consider alternative medication (LOINC#LA26421-0)

description: For clopidogrel, individuals with this diplotype are expected to have significantly reduced platelet inhibition, increased residual platelet aggregation and increased risk for adverse cardiovascular events in response to clopidogrel. Alternative antiplatelet therapy (if no contraindication) is recommended. Refer to current guidelines for dosage and recommendations at https://cpicpgx.org/guidelines/guideline- for-clopidogrel-and-cyp2c19/

for: Patient/CGPatientExample01 " EVERYMAN"

reasonReference: Observation/TxImp01: Poor metabolizer