HL7.FHIR.UV.GENOMICS-REPORTING\Variant - TTL Representation

This page is part of the Genetic Reporting Implementation Guide (v2.0.0: STU 2) based on FHIR R4. This is the current published version. For a full list of available versions, see the Directory of published versions
Resource Profile: Variant - TTL Profile

TTL representation of the variant resource profile.
Raw ttl | Download

@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:StructureDefinition;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "variant"];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" style=\"border: 0px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;\"><tr style=\"border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top\"><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"The logical name of the element\">Name</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Information about the use of the element\">Flags</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Minimum and Maximum # of times the the element can appear in the instance\">Card.</a></th><th style=\"width: 100px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Reference to the type of the element\">Type</a></th><th style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Additional information about the element\">Description &amp; Constraints</a><span style=\"float: right\"><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Legend for this format\"><img src=\"http://hl7.org/fhir/R4/help16.png\" alt=\"doco\" style=\"background-color: inherit\"/></a></span></th></tr><tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_resource.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Resource\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation\">Observation</a><a name=\"Observation\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">*</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"StructureDefinition-finding.html\">GenomicFinding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variant</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck11.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.code\">code</a><a name=\"Observation.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">69548-6<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck101.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">69548-6</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.valueCodeableConcept\" title=\"The presence or absence of the variant described in the components. If not searching for specific variations and merely reporting what's found, the profile's value should be set to 'Present'.\">valueCodeableConcept</a><a name=\"Observation.valueCodeableConcept\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Indeterminate | No call | Present | Absent.<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL1971-2.html\">LOINC Answer List LL1971-2</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck10.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.method\">method</a><a name=\"Observation.method\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Sequencing | SNP array | PCR | Computational analysis | ...<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL4048-6.html\">LOINC Answer List LL4048-6</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:coding-hgvs\" title=\"Slice coding-hgvs: Description of the coding (cDNA) sequence change using a valid HGVS-formatted string.\">component:coding-hgvs</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Coding (cDNA) Change - cHGVS</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:coding-hgvs.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">48004-6<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48004-6</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:coding-hgvs.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">A valid HGVS-formatted 'c.' string, e.g. NM_005228.5:c.2369C&gt;T.<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"ValueSet-hgvs-vs.html\">Human Genome Variation Society (HGVS) Nomenclature</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-hgvs\" title=\"Slice genomic-hgvs: Description of the genomic (gDNA) sequence change using a valid HGVS-formatted string.\">component:genomic-hgvs</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic (gDNA) Change - gHGVS</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-hgvs.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">81290-9<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81290-9</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-hgvs.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">A valid HGVS-formatted 'g.' string, e.g. NC_000016.9:g.2124200_2138612dup<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"ValueSet-hgvs-vs.html\">Human Genome Variation Society (HGVS) Nomenclature</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:cytogenomic-nomenclature\" title=\"Slice cytogenomic-nomenclature: Fully describes a variant with a single code. Typically a large variant such as a mosaic, abnormal chromosome numbers, etc.\">component:cytogenomic-nomenclature</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Cytogenomic Nomenclature (ISCN)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:cytogenomic-nomenclature.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">81291-7<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81291-7</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:cytogenomic-nomenclature.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">Actual component result</span><br/><span style=\"font-weight:bold\">Binding: </span><a href=\"http://hl7.org/fhir/R4/terminologies.html#unbound\">(unbound)</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set.  The value set merely provides examples of the types of concepts intended to be included.\">example</a>): Binding not yet defined<br/><br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-ref-seq\" title=\"Slice genomic-ref-seq: ID of the genomic reference sequence, which includes transcribed and non transcribed stretches\">component:genomic-ref-seq</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic Reference Sequence</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-ref-seq.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">48013-7<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48013-7</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-ref-seq.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Versioned genomic reference sequence identifier<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"http://hl7.org/fhir/R4/terminologies.html#unbound\">(unbound)</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set.  The value set merely provides examples of the types of concepts intended to be included.\">example</a>): Multiple bindings acceptable (NCBI or LRG)<br/><br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:transcript-ref-seq\" title=\"Slice transcript-ref-seq: NCBI's RefSeq ('NM_...'), Ensembl ('ENST...'), and LRG ('LRG...' plus 't1' to indicate transcript)\">component:transcript-ref-seq</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Reference Transcript</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:transcript-ref-seq.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">51958-7<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">51958-7</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:transcript-ref-seq.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Versioned transcript reference sequence identifier<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"http://hl7.org/fhir/R4/terminologies.html#unbound\">(unbound)</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set.  The value set merely provides examples of the types of concepts intended to be included.\">example</a>): Multiple bindings acceptable (NCBI or LRG)<br/><br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:exact-start-end\" title=\"Slice exact-start-end: The exact integer-based genomic coordinates of the start and end of the variant region.\">component:exact-start-end</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Exact Start-End</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:exact-start-end.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">81254-5<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81254-5</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:exact-start-end.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Range\">Range</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Range in question. 'High' can be omitted for single nucleotide variants.</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:inner-start-end\" title=\"Slice inner-start-end: The genomic coordinates of the narrowest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear.\">component:inner-start-end</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Inner Start-End</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:inner-start-end.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">81302-2<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81302-2</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:inner-start-end.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Range\">Range</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Imprecise variant inner-bounding range</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:outer-start-end\" title=\"Slice outer-start-end: The genomic coordinates of the widest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear.\">component:outer-start-end</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Outer Start-End</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:outer-start-end.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">81301-4<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81301-4</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:outer-start-end.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Range\">Range</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Imprecise variant outer-bounding range</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:coordinate-system\" title=\"Slice coordinate-system: These are different ways of identifying nucleotides or amino acids within a sequence. In the 1-based system, the first unit of the polymer (e.g. the first nucleotide) is counted as number 1. In the 0-based system, the number 0 designates the location before the first nucleotide. Different databases and file types may use different systems.\">component:coordinate-system</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Coordinate System</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:coordinate-system.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">92822-6<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">92822-6</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:coordinate-system.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0-based interval counting | 0-based character counting | 1-based character counting<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL5323-2.html\">LOINC Answer List LL5323-2</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:ref-allele\" title=\"Slice ref-allele: Reference values ('normal') examined within the Reference Sequence.\">component:ref-allele</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic Ref Allele</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:ref-allele.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">69547-8<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">69547-8</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:ref-allele.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Normalized string per the VCF format.</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:alt-allele\" title=\"Slice alt-allele: The genomic alternate allele is the contiguous segment of DNA in the test sample that differs from the reference allele at the same location and thus defines a variant.\">component:alt-allele</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic Alt Allele</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:alt-allele.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">69551-0<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">69551-0</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_primitive.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Primitive Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:alt-allele.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#string\">string</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Normalized string per the VCF format.</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:coding-change-type\" title=\"Slice coding-change-type: Type of DNA change observed. Convenience property for variants with exact breakpoints, required otherwise.\">component:coding-change-type</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Coding DNA Change Type</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:coding-change-type.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">48019-4<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48019-4</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:coding-change-type.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">deletion | insertion | delins | SNV | copy_number_gain | copy_number_loss | ... (many)<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"ValueSet-dna-change-type-vs.html\">DNA Change Type</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>): Concepts in sequence ontology under SO:0002072<br/><br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-source-class\" title=\"Slice genomic-source-class: The genomic class of the specimen being analyzed: Germline for inherited genome, somatic for cancer genome, and prenatal for fetal genome.\">component:genomic-source-class</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic Source Class</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-source-class.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">48002-0<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48002-0</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:genomic-source-class.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Germline | Somatic | Fetal | Likely germline | Likely somatic | Likely fetal | Unknown genomic origin | De novo<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL378-1.html\">LOINC Answer List LL378-1</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:sample-allelic-frequency\" title=\"Slice sample-allelic-frequency: The relative frequency of the allele at a given locus in the sample.\">component:sample-allelic-frequency</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Sample Allelic Frequency</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:sample-allelic-frequency.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">81258-6<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81258-6</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck141.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:sample-allelic-frequency.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Quantity\">Quantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Relative frequency in the sample</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1400.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:sample-allelic-frequency.value[x].system\">system</a><a name=\"Observation.component.value_x_.system\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">System that defines coded unit form</span><br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">http://unitsofmeasure.org</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-read-depth\" title=\"Slice allelic-read-depth: Specifies the number of reads that identified the allele in question whether it consists of one or a small sequence of contiguous nucleotides. Different methods and purposes require different numbers of reads to be acceptable. Often &gt;400, sometimes as few as 2-4.\">component:allelic-read-depth</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Allelic Read Depth</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-read-depth.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">82121-5<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">82121-5</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-read-depth.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Quantity\">Quantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Unfiltered count of supporting reads</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-state\" title=\"Slice allelic-state: The observed level of occurrence of the variant in the set of chromosomes.\">component:allelic-state</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Allelic State</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-state.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">53034-5<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">53034-5</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:allelic-state.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Heteroplasmic | Homoplasmic | Homozygous | Heterozygous | Hemizygous<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL381-5.html\">LOINC Answer List LL381-5</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-inheritance\" title=\"Slice variant-inheritance: By which parent the variant was inherited in the patient, if known.\">component:variant-inheritance</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variant Inheritance</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-inheritance.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">variant-inheritance<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"CodeSystem-tbd-codes-cs.html\">http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">variant-inheritance</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-inheritance.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Maternal | Paternal | Unknown<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"ValueSet-variant-inheritance-vs.html\">Variant Inheritances</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:variation-code\" title=\"Slice variation-code: Accession number in a variant database such as ClinVar, given for cross-reference.\">component:variation-code</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variation Code<br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:variation-code.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">81252-9<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">81252-9</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:variation-code.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">ClinVar ID or similar<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"http://hl7.org/fhir/R4/terminologies.html#unbound\">(unbound)</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#example\" title=\"Instances are not expected or even encouraged to draw from the specified value set.  The value set merely provides examples of the types of concepts intended to be included.\">example</a>): Multiple bindings acceptable<br/><br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:chromosome-identifier\" title=\"Slice chromosome-identifier: An indicator, enumerated in humans by numbers 1-22, X, and Y, representing the chromosome on which the variant is located.\">component:chromosome-identifier</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Chromosome Identifier<br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:chromosome-identifier.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">48000-4<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48000-4</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:chromosome-identifier.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Chromosome 1 | Chromosome 2 | ... | Chromosome 22 | Chromosome X | Chromosome Y<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL2938-0.html\">LOINC Answer List LL2938-0</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:protein-hgvs\" title=\"Slice protein-hgvs: Description of the protein (amino acid) sequence change using a valid HGVS-formatted string. The description of the variant is surrounded in parentheses if it is calculated rather than directly observed.\">component:protein-hgvs</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Protein (Amino Acid) Change - pHGVS</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:protein-hgvs.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">48005-3<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48005-3</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:protein-hgvs.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">A valid HGVS-formatted 'p.' string, e.g. NP_000050.2:p.(Asn1836Lys)<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"ValueSet-hgvs-vs.html\">Human Genome Variation Society (HGVS) Nomenclature</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:amino-acid-change-type\" title=\"Slice amino-acid-change-type: Codified type for associated Amino Acid Marker, for convenience.\">component:amino-acid-change-type</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Amino Acid Change Type</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:amino-acid-change-type.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">48006-1<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">48006-1</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:amino-acid-change-type.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Wild type | Deletion | Duplication | Frameshift | Initiating Methionine | Insertion | Insertion and Deletion | Missense | Nonsense | Silent<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"https://r.details.loinc.org/AnswerList/LL380-7.html\">LOINC Answer List LL380-7</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>)</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:molecular-consequence\" title=\"Slice molecular-consequence: The calculated or observed effect of a variant on its downstream transcript and, if applicable, ensuing protein sequence.\">component:molecular-consequence</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Molecular Consequence</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:molecular-consequence.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">molecular-consequence<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"CodeSystem-tbd-codes-cs.html\">http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">molecular-consequence</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:molecular-consequence.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">stop_lost | stop_gained | inframe_insertion | frameshift_variant | ... (many)<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"ValueSet-molecular-consequence-vs.html\">Molecular Consequence</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#extensible\" title=\"To be conformant, the concept in this element SHALL be from the specified value set if any of the codes within the value set can apply to the concept being communicated.  If the value set does not cover the concept (based on human review), alternate codings (or, data type allowing, text) may be included instead.\">extensible</a>): Concepts in sequence ontology under SO:0001537.<br/><br/></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:copy-number\" title=\"Slice copy-number: The copy number of the large variant. In HGVS, this is the numeric value following the “X”. It is a unit-less value. Note that a copy number of 1 can imply a deletion.\">component:copy-number</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Genomic Structural Variant Copy Number</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck151.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:copy-number.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">82155-3<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck1501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-loinc.html\">http://loinc.org</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck15000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">82155-3</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck140.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:copy-number.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"padding-left: 3px; padding-right: 3px; color: black; null\" title=\"This element has or is affected by some invariants (cnt-3)\">I</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">0</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Quantity\">Quantity</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">Actual component result</span><br/><span style=\"font-weight:bold\">cnt-3: </span>There SHALL be a code with a value of '1' if there is a value. If system is present, it SHALL be UCUM. If present, the value SHALL be a whole number.</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck05.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_slice_item.png\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Slice Item\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-confidence-status\" title=\"Slice variant-confidence-status: A code that represents the confidence of a true positive variant call.\">component:variant-confidence-status</a><a name=\"Observation.component\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">0..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#BackboneElement\">BackboneElement</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Variant Confidence Status</td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck051.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_element.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Element\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-confidence-status.code\">code</a><a name=\"Observation.component.code\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><span style=\"opacity: 0.5\">1</span><span style=\"opacity: 0.5\">..</span><span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a style=\"opacity: 0.5\" href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">variant-confidence-status<br/><span style=\"font-weight:bold\">Required Pattern: </span><span style=\"color: darkgreen\">At least the following</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck0501.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#CodeableConcept.coding\">coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..*</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#Coding\">Coding</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Code defined by a terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">(complex)</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck05010.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.system\">system</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#uri\">uri</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Identity of the terminology system<br/><span style=\"font-weight: bold\">Fixed Value: </span><a style=\"color: darkgreen\" href=\"CodeSystem-tbd-codes-cs.html\">http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs</a></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: white\"><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck05000.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vline_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_fixed.gif\" alt=\".\" style=\"background-color: white; background-color: inherit\" title=\"Fixed Value\" class=\"hierarchy\"/> <a href=\"http://hl7.org/fhir/R4/datatypes-definitions.html#Coding.code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..1</td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#code\">code</a></td><td style=\"vertical-align: top; text-align : left; background-color: white; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">Symbol in syntax defined by the system<br/><span style=\"font-weight: bold\">Fixed Value: </span><span style=\"color: darkgreen\">variant-confidence-status</span></td></tr>\r\n<tr style=\"border: 0px #F0F0F0 solid; padding:0px; vertical-align: top; background-color: #F7F7F7\"><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px; white-space: nowrap; background-image: url(tbl_bck040.png)\" class=\"hierarchy\"><img src=\"tbl_spacer.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_blank.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"tbl_vjoin_end_slice.png\" alt=\".\" style=\"background-color: inherit\" class=\"hierarchy\"/><img src=\"icon_datatype.gif\" alt=\".\" style=\"background-color: #F7F7F7; background-color: inherit\" title=\"Data Type\" class=\"hierarchy\"/> <a href=\"StructureDefinition-variant-definitions.html#Observation.component:variant-confidence-status.value[x]\">value[x]</a><a name=\"Observation.component.value_x_\"> </a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"/><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">1..<span style=\"opacity: 0.5\">1</span></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\"><a href=\"http://hl7.org/fhir/R4/datatypes.html#CodeableConcept\">CodeableConcept</a></td><td style=\"vertical-align: top; text-align : left; background-color: #F7F7F7; border: 0px #F0F0F0 solid; padding:0px 4px 0px 4px\" class=\"hierarchy\">High | Intermediate | Low<br/><span style=\"font-weight:bold\">Binding: </span><a href=\"ValueSet-variant-confidence-status-vs.html\">Variant Confidence Status</a> (<a href=\"http://hl7.org/fhir/R4/terminologies.html#required\" title=\"To be conformant, the concept in this element SHALL be from the specified value set.\">required</a>)</td></tr>\r\n<tr><td colspan=\"5\" class=\"hierarchy\"><br/><a href=\"http://hl7.org/fhir/R4/formats.html#table\" title=\"Legend for this format\"><img src=\"http://hl7.org/fhir/R4/help16.png\" alt=\"doco\" style=\"background-color: inherit\"/> Documentation for this format</a></td></tr></table></div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-category" ];
     fhir:Extension.valueString [ fhir:value "Clinical.Diagnostics" ]
  ], [
     fhir:index 1;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-security-category" ];
     fhir:Extension.valueCode [ fhir:value "patient" ]
  ];
  fhir:StructureDefinition.url [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant"];
  fhir:StructureDefinition.version [ fhir:value "2.0.0"];
  fhir:StructureDefinition.name [ fhir:value "Variant"];
  fhir:StructureDefinition.title [ fhir:value "Variant"];
  fhir:StructureDefinition.status [ fhir:value "active"];
  fhir:StructureDefinition.date [ fhir:value "2022-05-09T16:59:16+00:00"^^xsd:dateTime];
  fhir:StructureDefinition.publisher [ fhir:value "HL7 Clinical Genomics Working Group"];
  fhir:StructureDefinition.contact [
     fhir:index 0;
     fhir:ContactDetail.name [ fhir:value "HL7 Clinical Genomics Working Group" ];
     fhir:ContactDetail.telecom [
       fhir:index 0;
       fhir:ContactPoint.system [ fhir:value "url" ];
       fhir:ContactPoint.value [ fhir:value "http://www.hl7.org/Special/committees/clingenomics" ]     ], [
       fhir:index 1;
       fhir:ContactPoint.system [ fhir:value "email" ];
       fhir:ContactPoint.value [ fhir:value "cg@lists.HL7.org" ]     ]
  ];
  fhir:StructureDefinition.description [ fhir:value "Details about a set of changes in the tested sample compared to a reference sequence."];
  fhir:StructureDefinition.jurisdiction [
     fhir:index 0;
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://unstats.un.org/unsd/methods/m49/m49.htm" ];
       fhir:Coding.code [ fhir:value "001" ];
       fhir:Coding.display [ fhir:value "World" ]     ]
  ];
  fhir:StructureDefinition.copyright [ fhir:value "This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc."];
  fhir:StructureDefinition.fhirVersion [ fhir:value "4.0.1"];
  fhir:StructureDefinition.mapping [
     fhir:index 0;
     fhir:StructureDefinition.mapping.identity [ fhir:value "workflow" ];
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/fhir/workflow" ];
     fhir:StructureDefinition.mapping.name [ fhir:value "Workflow Pattern" ]
  ], [
     fhir:index 1;
     fhir:StructureDefinition.mapping.identity [ fhir:value "sct-concept" ];
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://snomed.info/conceptdomain" ];
     fhir:StructureDefinition.mapping.name [ fhir:value "SNOMED CT Concept Domain Binding" ]
  ], [
     fhir:index 2;
     fhir:StructureDefinition.mapping.identity [ fhir:value "v2" ];
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/v2" ];
     fhir:StructureDefinition.mapping.name [ fhir:value "HL7 v2 Mapping" ]
  ], [
     fhir:index 3;
     fhir:StructureDefinition.mapping.identity [ fhir:value "rim" ];
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/v3" ];
     fhir:StructureDefinition.mapping.name [ fhir:value "RIM Mapping" ]
  ], [
     fhir:index 4;
     fhir:StructureDefinition.mapping.identity [ fhir:value "w5" ];
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://hl7.org/fhir/fivews" ];
     fhir:StructureDefinition.mapping.name [ fhir:value "FiveWs Pattern Mapping" ]
  ], [
     fhir:index 5;
     fhir:StructureDefinition.mapping.identity [ fhir:value "sct-attr" ];
     fhir:StructureDefinition.mapping.uri [ fhir:value "http://snomed.org/attributebinding" ];
     fhir:StructureDefinition.mapping.name [ fhir:value "SNOMED CT Attribute Binding" ]
  ];
  fhir:StructureDefinition.kind [ fhir:value "resource"];
  fhir:StructureDefinition.abstract [ fhir:value "false"^^xsd:boolean];
  fhir:StructureDefinition.type [ fhir:value "Observation"];
  fhir:StructureDefinition.baseDefinition [
     fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding";
     fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding>
  ];
  fhir:StructureDefinition.derivation [ fhir:value "constraint"];
  fhir:StructureDefinition.snapshot [
     fhir:StructureDefinition.snapshot.element [
       fhir:index 0;
       fhir:Element.id [ fhir:value "Observation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation" ];
       fhir:ElementDefinition.short [ fhir:value "Variant" ];
       fhir:ElementDefinition.definition [ fhir:value "Measurements and simple assertions made about a patient, device or other subject." ];
       fhir:ElementDefinition.comment [ fhir:value "Used for simple observations such as device measurements, laboratory atomic results, vital signs, height, weight, smoking status, comments, etc.  Other resources are used to provide context for observations such as laboratory reports, etc." ];
       fhir:ElementDefinition.alias [
         fhir:value "Vital Signs";
         fhir:index 0       ], [
         fhir:value "Measurement";
         fhir:index 1       ], [
         fhir:value "Results";
         fhir:index 2       ], [
         fhir:value "Tests";
         fhir:index 3       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "dom-2" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "If the resource is contained in another resource, it SHALL NOT contain nested Resources" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "contained.contained.empty()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(parent::f:contained and f:contained)" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource";
           fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "dom-3" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource";
           fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>         ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.constraint.key [ fhir:value "dom-4" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource";
           fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>         ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.constraint.key [ fhir:value "dom-5" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "If a resource is contained in another resource, it SHALL NOT have a security label" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "contained.meta.security.empty()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:contained/*/f:meta/f:security))" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource";
           fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>         ]       ], [
         fhir:index 4;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice" ];
           fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]         ], [
           fhir:index 1;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation" ];
           fhir:Extension.valueMarkdown [ fhir:value "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time." ]         ];
         fhir:ElementDefinition.constraint.key [ fhir:value "dom-6" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "warning" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "A resource should have narrative for robust management" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "text.`div`.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:text/h:div)" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DomainResource";
           fhir:link <http://hl7.org/fhir/StructureDefinition/DomainResource>         ]       ], [
         fhir:index 5;
         fhir:ElementDefinition.constraint.key [ fhir:value "obs-6" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "dataAbsentReason SHALL only be present if Observation.value[x] is not present" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "dataAbsentReason.empty() or value.empty()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(exists(f:dataAbsentReason)) or (not(exists(*[starts-with(local-name(.), 'value')])))" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Observation";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Observation>         ]       ], [
         fhir:index 6;
         fhir:ElementDefinition.constraint.key [ fhir:value "obs-7" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "If Observation.code is the same as an Observation.component.code then the value element associated with the code SHALL NOT be present" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "value.empty() or component.code.where(coding.intersect(%resource.code.coding).exists()).empty()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "not(f:*[starts-with(local-name(.), 'value')] and (for $coding in f:code/f:coding return f:component/f:code/f:coding[f:code/@value=$coding/f:code/@value] [f:system/@value=$coding/f:system/@value]))" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Observation";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Observation>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Entity. Role, or Act" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Event" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity|" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX" ]       ], [
         fhir:index 4;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Observation[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 1;
       fhir:Element.id [ fhir:value "Observation.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.id" ];
       fhir:ElementDefinition.short [ fhir:value "Logical id of this artifact" ];
       fhir:ElementDefinition.definition [ fhir:value "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes." ];
       fhir:ElementDefinition.comment [ fhir:value "The only time that a resource does not have an id is when it is being submitted to the server using a create operation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Resource.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]     ], [
       fhir:index 2;
       fhir:Element.id [ fhir:value "Observation.meta" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.meta" ];
       fhir:ElementDefinition.short [ fhir:value "Metadata about the resource" ];
       fhir:ElementDefinition.definition [ fhir:value "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Resource.meta" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Meta" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]     ], [
       fhir:index 3;
       fhir:Element.id [ fhir:value "Observation.implicitRules" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.implicitRules" ];
       fhir:ElementDefinition.short [ fhir:value "A set of rules under which this content was created" ];
       fhir:ElementDefinition.definition [ fhir:value "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc." ];
       fhir:ElementDefinition.comment [ fhir:value "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Resource.implicitRules" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "uri" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ]     ], [
       fhir:index 4;
       fhir:Element.id [ fhir:value "Observation.language" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.language" ];
       fhir:ElementDefinition.short [ fhir:value "Language of the resource content" ];
       fhir:ElementDefinition.definition [ fhir:value "The base language in which the resource is written." ];
       fhir:ElementDefinition.comment [ fhir:value "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies  to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute)." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Resource.language" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "code" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet" ];
           fhir:Extension.valueCanonical [
             fhir:value "http://hl7.org/fhir/ValueSet/all-languages";
             fhir:link <http://hl7.org/fhir/ValueSet/all-languages>           ]         ], [
           fhir:index 1;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "Language" ]         ], [
           fhir:index 2;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding" ];
           fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ];
         fhir:ElementDefinition.binding.description [ fhir:value "A human language." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/languages";
           fhir:link <http://hl7.org/fhir/ValueSet/languages>         ]       ]     ], [
       fhir:index 5;
       fhir:Element.id [ fhir:value "Observation.text" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.text" ];
       fhir:ElementDefinition.short [ fhir:value "Text summary of the resource, for human interpretation" ];
       fhir:ElementDefinition.definition [ fhir:value "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety." ];
       fhir:ElementDefinition.comment [ fhir:value "Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later." ];
       fhir:ElementDefinition.alias [
         fhir:value "narrative";
         fhir:index 0       ], [
         fhir:value "html";
         fhir:index 1       ], [
         fhir:value "xhtml";
         fhir:index 2       ], [
         fhir:value "display";
         fhir:index 3       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.text" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Narrative" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Act.text?" ]       ]     ], [
       fhir:index 6;
       fhir:Element.id [ fhir:value "Observation.contained" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.contained" ];
       fhir:ElementDefinition.short [ fhir:value "Contained, inline Resources" ];
       fhir:ElementDefinition.definition [ fhir:value "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope." ];
       fhir:ElementDefinition.comment [ fhir:value "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels." ];
       fhir:ElementDefinition.alias [
         fhir:value "inline resources";
         fhir:index 0       ], [
         fhir:value "anonymous resources";
         fhir:index 1       ], [
         fhir:value "contained resources";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.contained" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Resource" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 7;
       fhir:Element.id [ fhir:value "Observation.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.extension" ];
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ];
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]         ];
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ];
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]       ];
       fhir:ElementDefinition.short [ fhir:value "Extension" ];
       fhir:ElementDefinition.definition [ fhir:value "An Extension" ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ]     ], [
       fhir:index 8;
       fhir:Element.id [ fhir:value "Observation.extension:secondary-finding" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.extension" ];
       fhir:ElementDefinition.sliceName [ fhir:value "secondary-finding" ];
       fhir:ElementDefinition.short [ fhir:value "Secondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when [Whole Exome Sequencing (WES)](https://en.wikipedia.org/wiki/Exome_sequencing) or [Whole Genome Sequencing (WGS)](https://en.wikipedia.org/wiki/Whole_genome_sequencing) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement.\n\nFor more detail, please see:\nhttps://ghr.nlm.nih.gov/primer/testing/secondaryfindings" ];
       fhir:ElementDefinition.definition [ fhir:value "Secondary findings are genetic test results that provide information about variants in a gene unrelated to the primary purpose for the testing, most often discovered when [Whole Exome Sequencing (WES)](https://en.wikipedia.org/wiki/Exome_sequencing) or [Whole Genome Sequencing (WGS)](https://en.wikipedia.org/wiki/Whole_genome_sequencing) is performed. This extension should be used to denote when a genetic finding is being shared as a secondary finding, and ideally refer to a corresponding guideline or policy statement.\n\nFor more detail, please see:\nhttps://ghr.nlm.nih.gov/primer/testing/secondaryfindings." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ];
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/observation-secondaryFinding>         ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "ele-1";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]     ], [
       fhir:index 9;
       fhir:Element.id [ fhir:value "Observation.extension:body-structure" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.extension" ];
       fhir:ElementDefinition.sliceName [ fhir:value "body-structure" ];
       fhir:ElementDefinition.short [ fhir:value "Target anatomic location or structure" ];
       fhir:ElementDefinition.definition [ fhir:value "Record details about the anatomical location of a specimen or body part. This resource may be used when a coded concept does not provide the necessary detail needed for the use case." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ];
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/bodySite";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/bodySite>         ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "ele-1";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ]     ], [
       fhir:index 10;
       fhir:Element.id [ fhir:value "Observation.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "DomainResource.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 11;
       fhir:Element.id [ fhir:value "Observation.identifier" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.identifier" ];
       fhir:ElementDefinition.short [ fhir:value "Business Identifier for observation" ];
       fhir:ElementDefinition.definition [ fhir:value "A unique identifier assigned to this observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Allows observations to be distinguished and referenced." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.identifier" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Identifier" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.identifier" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.identifier" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.21  For OBX segments from systems without OBX-21 support a combination of ORC/OBR and OBX must be negotiated between trading partners to uniquely identify the OBX segment. Depending on how V2 has been implemented each of these may be an option: 1) OBR-3 + OBX-3 + OBX-4 or 2) OBR-3 + OBR-4 + OBX-3 + OBX-4 or 2) some other way to uniquely ID the OBR/ORC + OBX-3 + OBX-4." ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "id" ]       ]     ], [
       fhir:index 12;
       fhir:Element.id [ fhir:value "Observation.basedOn" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.basedOn" ];
       fhir:ElementDefinition.short [ fhir:value "Fulfills plan, proposal or order" ];
       fhir:ElementDefinition.definition [ fhir:value "A plan, proposal or order that is fulfilled in whole or in part by this event.  For example, a MedicationRequest may require a patient to have laboratory test performed before  it is dispensed." ];
       fhir:ElementDefinition.requirements [ fhir:value "Allows tracing of authorization for the event and tracking whether proposals/recommendations were acted upon." ];
       fhir:ElementDefinition.alias [
         fhir:value "Fulfills";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.basedOn" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ];
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/CarePlan";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/CarePlan>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DeviceRequest";
           fhir:index 1;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DeviceRequest>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/ImmunizationRecommendation";
           fhir:index 2;
           fhir:link <http://hl7.org/fhir/StructureDefinition/ImmunizationRecommendation>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationRequest";
           fhir:index 3;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationRequest>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/NutritionOrder";
           fhir:index 4;
           fhir:link <http://hl7.org/fhir/StructureDefinition/NutritionOrder>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/ServiceRequest";
           fhir:index 5;
           fhir:link <http://hl7.org/fhir/StructureDefinition/ServiceRequest>         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.basedOn" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "ORC" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value ".inboundRelationship[typeCode=COMP].source[moodCode=EVN]" ]       ]     ], [
       fhir:index 13;
       fhir:Element.id [ fhir:value "Observation.partOf" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.partOf" ];
       fhir:ElementDefinition.short [ fhir:value "Part of referenced event" ];
       fhir:ElementDefinition.definition [ fhir:value "A larger event of which this particular Observation is a component or step.  For example,  an observation as part of a procedure." ];
       fhir:ElementDefinition.comment [ fhir:value "To link an Observation to an Encounter use `encounter`.  See the  [Notes](http://hl7.org/fhir/R4/observation.html#obsgrouping) below for guidance on referencing another Observation." ];
       fhir:ElementDefinition.alias [
         fhir:value "Container";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.partOf" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ];
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationAdministration";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationAdministration>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationDispense";
           fhir:index 1;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationDispense>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MedicationStatement";
           fhir:index 2;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MedicationStatement>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Procedure";
           fhir:index 3;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Procedure>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Immunization";
           fhir:index 4;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Immunization>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/ImagingStudy";
           fhir:index 5;
           fhir:link <http://hl7.org/fhir/StructureDefinition/ImagingStudy>         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.partOf" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Varies by domain" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value ".outboundRelationship[typeCode=FLFS].target" ]       ]     ], [
       fhir:index 14;
       fhir:Element.id [ fhir:value "Observation.status" ];
       fhir:Element.extension [
         fhir:index 0;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-display-hint" ];
         fhir:Extension.valueString [ fhir:value "default: final" ]       ];
       fhir:ElementDefinition.path [ fhir:value "Observation.status" ];
       fhir:ElementDefinition.short [ fhir:value "registered | preliminary | final | amended +" ];
       fhir:ElementDefinition.definition [ fhir:value "The status of the result value." ];
       fhir:ElementDefinition.comment [ fhir:value "This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid." ];
       fhir:ElementDefinition.requirements [ fhir:value "Need to track the status of individual results. Some results are finalized before the whole report is finalized." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.status" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "code" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "This element is labeled as a modifier because it is a status element that contains status entered-in-error which means that the resource should not be treated as valid" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationStatus" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes providing the status of an observation." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-status|4.0.1";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-status|4.0.1>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.status" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.status" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 445584004 |Report by finality status|" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-11" ]       ], [
         fhir:index 4;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "status  Amended & Final are differentiated by whether it is the subject of a ControlAct event with a type of \"revise\"" ]       ]     ], [
       fhir:index 15;
       fhir:Element.id [ fhir:value "Observation.category" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.category" ];
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ];
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "coding" ]         ];
         fhir:ElementDefinition.slicing.description [ fhir:value "Slice based on the category.code pattern" ];
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ];
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]       ];
       fhir:ElementDefinition.short [ fhir:value "Classification of  type of observation" ];
       fhir:ElementDefinition.definition [ fhir:value "A code that classifies the general type of observation being made." ];
       fhir:ElementDefinition.comment [ fhir:value "In addition to the required category valueset, this element allows various categorization schemes based on the owner’s definition of the category and effectively multiple categories can be used at once.  The level of granularity is defined by the category concepts in the value set." ];
       fhir:ElementDefinition.requirements [ fhir:value "Used for filtering what observations are retrieved and displayed." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.category" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCategory" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes for high level observation categories." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-category";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-category>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.class" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value ".outboundRelationship[typeCode=\"COMP].target[classCode=\"LIST\", moodCode=\"EVN\"].code" ]       ]     ], [
       fhir:index 16;
       fhir:Element.id [ fhir:value "Observation.category:labCategory" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.category" ];
       fhir:ElementDefinition.sliceName [ fhir:value "labCategory" ];
       fhir:ElementDefinition.short [ fhir:value "Classification of  type of observation" ];
       fhir:ElementDefinition.definition [ fhir:value "A code that classifies the general type of observation being made." ];
       fhir:ElementDefinition.comment [ fhir:value "In addition to the required category valueset, this element allows various categorization schemes based on the owner’s definition of the category and effectively multiple categories can be used at once.  The level of granularity is defined by the category concepts in the value set." ];
       fhir:ElementDefinition.requirements [ fhir:value "Used for filtering what observations are retrieved and displayed." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.category" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCategory" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes for high level observation categories." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-category";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-category>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.class" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value ".outboundRelationship[typeCode=\"COMP].target[classCode=\"LIST\", moodCode=\"EVN\"].code" ]       ]     ], [
       fhir:index 17;
       fhir:Element.id [ fhir:value "Observation.category:labCategory.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.category.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 18;
       fhir:Element.id [ fhir:value "Observation.category:labCategory.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.category.extension" ];
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ];
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]         ];
         fhir:ElementDefinition.slicing.description [ fhir:value "Extensions are always sliced by (at least) url" ];
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]       ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 19;
       fhir:Element.id [ fhir:value "Observation.category:labCategory.coding" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.category.coding" ];
       fhir:ElementDefinition.short [ fhir:value "Code defined by a terminology system" ];
       fhir:ElementDefinition.definition [ fhir:value "A reference to a code defined by a terminology system." ];
       fhir:ElementDefinition.comment [ fhir:value "Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information.  Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true." ];
       fhir:ElementDefinition.requirements [ fhir:value "Allows for alternative encodings within a code system, and translations to other code systems." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "CodeableConcept.coding" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Coding" ]       ];
       fhir:ElementDefinition.patternCoding [
         fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/observation-category" ];
         fhir:Coding.code [ fhir:value "laboratory" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "C*E.1-8, C*E.10-22" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "union(., ./translation)" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "orim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "fhir:CodeableConcept.coding rdfs:subPropertyOf dt:CD.coding" ]       ]     ], [
       fhir:index 20;
       fhir:Element.id [ fhir:value "Observation.category:labCategory.text" ];
       fhir:Element.extension [
         fhir:index 0;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable" ];
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]       ];
       fhir:ElementDefinition.path [ fhir:value "Observation.category.text" ];
       fhir:ElementDefinition.short [ fhir:value "Plain text representation of the concept" ];
       fhir:ElementDefinition.definition [ fhir:value "A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user." ];
       fhir:ElementDefinition.comment [ fhir:value "Very often the text is the same as a displayName of one of the codings." ];
       fhir:ElementDefinition.requirements [ fhir:value "The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "CodeableConcept.text" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "C*E.9. But note many systems use C*E.2 for this" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "./originalText[mediaType/code=\"text/plain\"]/data" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "orim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "fhir:CodeableConcept.text rdfs:subPropertyOf dt:CD.originalText" ]       ]     ], [
       fhir:index 21;
       fhir:Element.id [ fhir:value "Observation.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.code" ];
       fhir:ElementDefinition.short [ fhir:value "69548-6" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"name\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and, if present, component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.alias [
         fhir:value "Name";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:69548-6;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "69548-6" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.code" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR < 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 4;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ], [
         fhir:index 5;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "116680003 |Is a|" ]       ]     ], [
       fhir:index 22;
       fhir:Element.id [ fhir:value "Observation.subject" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.subject" ];
       fhir:ElementDefinition.short [ fhir:value "Who and/or what the observation is about" ];
       fhir:ElementDefinition.definition [ fhir:value "The patient, or group of patients, location, or device this observation is about and into whose record the observation is placed. If the actual focus of the observation is different from the subject (or a sample of, part, or region of the subject), the `focus` element or the `code` itself specifies the actual focus of the observation." ];
       fhir:ElementDefinition.comment [ fhir:value "One would expect this element to be a cardinality of 1..1. The only circumstance in which the subject can be missing is when the observation is made by a device that does not know the patient. In this case, the observation SHALL be matched to a patient through some context/channel matching technique, and at this point, the observation should be updated." ];
       fhir:ElementDefinition.requirements [ fhir:value "Observations have no value if you don't know who or what they're about." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.subject" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ];
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Patient";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Patient>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Group";
           fhir:index 1;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Group>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Device";
           fhir:index 2;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Device>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Location";
           fhir:index 3;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Location>         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.subject" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject[x]" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "PID-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=RTGT]" ]       ], [
         fhir:index 4;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject" ]       ]     ], [
       fhir:index 23;
       fhir:Element.id [ fhir:value "Observation.focus" ];
       fhir:Element.extension [
         fhir:index 0;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status" ];
         fhir:Extension.valueCode [ fhir:value "trial-use" ]       ];
       fhir:ElementDefinition.path [ fhir:value "Observation.focus" ];
       fhir:ElementDefinition.short [ fhir:value "What the observation is about, when it is not about the subject of record" ];
       fhir:ElementDefinition.definition [ fhir:value "The actual focus of an observation when it is not the patient of record representing something or someone associated with the patient such as a spouse, parent, fetus, or donor. For example, fetus observations in a mother's record.  The focus of an observation could also be an existing condition,  an intervention, the subject's diet,  another observation of the subject,  or a body structure such as tumor or implanted device.   An example use case would be using the Observation resource to capture whether the mother is trained to change her child's tracheostomy tube. In this example, the child is the patient of record and the mother is the focus." ];
       fhir:ElementDefinition.comment [ fhir:value "Typically, an observation is made about the subject - a patient, or group of patients, location, or device - and the distinction between the subject and what is directly measured for an observation is specified in the observation code itself ( e.g., \"Blood Glucose\") and does not need to be represented separately using this element.  Use `specimen` if a reference to a specimen is required.  If a code is required instead of a resource use either  `bodysite` for bodysites or the standard extension [focusCode](http://hl7.org/fhir/R4/extension-observation-focuscode.html)." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.focus" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ];
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Resource";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Resource>         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=SBJ]" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.subject" ]       ]     ], [
       fhir:index 24;
       fhir:Element.id [ fhir:value "Observation.encounter" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.encounter" ];
       fhir:ElementDefinition.short [ fhir:value "Healthcare event during which this observation is made" ];
       fhir:ElementDefinition.definition [ fhir:value "The healthcare event  (e.g. a patient and healthcare provider interaction) during which this observation is made." ];
       fhir:ElementDefinition.comment [ fhir:value "This will typically be the encounter the event occurred within, but some events may be initiated prior to or after the official completion of an encounter but still be tied to the context of the encounter (e.g. pre-admission laboratory tests)." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some observations it may be important to know the link between an observation and a particular encounter." ];
       fhir:ElementDefinition.alias [
         fhir:value "Context";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.encounter" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ];
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Encounter";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Encounter>         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.context" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.context" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "PV1" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "inboundRelationship[typeCode=COMP].source[classCode=ENC, moodCode=EVN]" ]       ]     ], [
       fhir:index 25;
       fhir:Element.id [ fhir:value "Observation.effective[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.effective[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Clinically relevant time/time-period for observation" ];
       fhir:ElementDefinition.definition [ fhir:value "The time or time-period the observed value is asserted as being true. For biological subjects - e.g. human patients - this is usually called the \"physiologically relevant time\". This is usually either the time of the procedure or of specimen collection, but very often the source of the date/time is not known, only the date/time itself." ];
       fhir:ElementDefinition.comment [ fhir:value "At least a date should be present unless this observation is a historical report.  For recording imprecise or \"fuzzy\" times (For example, a blood glucose measurement taken \"after breakfast\") use the [Timing](http://hl7.org/fhir/R4/datatypes.html#timing) datatype which allow the measurement to be tied to regular life events." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing when an observation was deemed true is important to its relevance as well as determining trends." ];
       fhir:ElementDefinition.alias [
         fhir:value "Occurrence";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.effective[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "dateTime" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.type.code [ fhir:value "Period" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.type.code [ fhir:value "Timing" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.type.code [ fhir:value "instant" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.occurrence[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.done[x]" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-14, and/or OBX-19 after v2.4  (depends on who observation made)" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "effectiveTime" ]       ]     ], [
       fhir:index 26;
       fhir:Element.id [ fhir:value "Observation.issued" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.issued" ];
       fhir:ElementDefinition.short [ fhir:value "Date/Time this version was made available" ];
       fhir:ElementDefinition.definition [ fhir:value "The date and time this version of the observation was made available to providers, typically after the results have been reviewed and verified." ];
       fhir:ElementDefinition.comment [ fhir:value "For Observations that don’t require review and verification, it may be the same as the [`lastUpdated` ](http://hl7.org/fhir/R4/resource-definitions.html#Meta.lastUpdated) time of the resource itself.  For Observations that do require review and verification for certain updates, it might not be the same as the `lastUpdated` time of the resource itself due to a non-clinically significant update that doesn’t require the new version to be reviewed and verified again." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.issued" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "instant" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.recorded" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBR.22 (or MSH.7), or perhaps OBX-19 (depends on who observation made)" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=AUT].time" ]       ]     ], [
       fhir:index 27;
       fhir:Element.id [ fhir:value "Observation.performer" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.performer" ];
       fhir:ElementDefinition.short [ fhir:value "Who is responsible for the observation" ];
       fhir:ElementDefinition.definition [ fhir:value "Who was responsible for asserting the observed value as \"true\"." ];
       fhir:ElementDefinition.requirements [ fhir:value "May give a degree of confidence in the observation and also indicates where follow-up questions should be directed." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.performer" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ];
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Practitioner";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Practitioner>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/PractitionerRole";
           fhir:index 1;
           fhir:link <http://hl7.org/fhir/StructureDefinition/PractitionerRole>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Organization";
           fhir:index 2;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Organization>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/CareTeam";
           fhir:index 3;
           fhir:link <http://hl7.org/fhir/StructureDefinition/CareTeam>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Patient";
           fhir:index 4;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Patient>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/RelatedPerson";
           fhir:index 5;
           fhir:link <http://hl7.org/fhir/StructureDefinition/RelatedPerson>         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "workflow" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Event.performer.actor" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.actor" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.15 / (Practitioner)  OBX-16,  PRT-5:PRT-4='RO' /  (Device)  OBX-18 , PRT-10:PRT-4='EQUIP' / (Organization)  OBX-23,  PRT-8:PRT-4='PO'" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=PRF]" ]       ]     ], [
       fhir:index 28;
       fhir:Element.id [ fhir:value "Observation.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ];
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "type" ];
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "$this" ]         ];
         fhir:ElementDefinition.slicing.ordered [ fhir:value "false"^^xsd:boolean ];
         fhir:ElementDefinition.slicing.rules [ fhir:value "closed" ]       ];
       fhir:ElementDefinition.short [ fhir:value "Actual result" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-7";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 29;
       fhir:Element.id [ fhir:value "Observation.value[x]:valueCodeableConcept" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.value[x]" ];
       fhir:ElementDefinition.sliceName [ fhir:value "valueCodeableConcept" ];
       fhir:ElementDefinition.short [ fhir:value "Indeterminate | No call | Present | Absent." ];
       fhir:ElementDefinition.definition [ fhir:value "The presence or absence of the variant described in the components. If not searching for specific variations and merely reporting what's found, the profile's value should be set to 'Present'." ];
       fhir:ElementDefinition.comment [ fhir:value "An observation may have; 1)  a single value here, 2)  both a value and a set of related or component values,  or 3)  only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code.  A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-7";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL1971-2";
           fhir:link <http://loinc.org/vs/LL1971-2>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 30;
       fhir:Element.id [ fhir:value "Observation.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "Null or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"specimen unsatisfactory\".   \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed. Note that an observation may only be reported if there are values to report. For example differential cell counts values may be reported only when > 0.  Because of these options, use-case agreements are required to interpret general observations for null or exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 31;
       fhir:Element.id [ fhir:value "Observation.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 32;
       fhir:Element.id [ fhir:value "Observation.note" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.note" ];
       fhir:ElementDefinition.short [ fhir:value "Comments about the Observation that also contain a coded type" ];
       fhir:ElementDefinition.definition [ fhir:value "A  text note which also  contains information about who made the statement and when." ];
       fhir:ElementDefinition.comment [ fhir:value "May include general statements about the observation, or statements about significant, unexpected or unreliable results values, or information about its source when relevant to its interpretation.\nThe CodedAnnotation data type, while not allowing for or intending to make the content computable, does allow the author to indicate the type of note. This does not replace the use of interpretation, value, or component values.\nOne important note is that Annotation is a FHIR data type, this is **NOT** about annotations in the genomic context." ];
       fhir:ElementDefinition.requirements [ fhir:value "Need to be able to provide free text additional information. Notes SHALL NOT contain information which can be captured in a structured way." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.note" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Annotation" ];
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/coded-annotation";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/coded-annotation>         ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "ele-1";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Act" ]       ]     ], [
       fhir:index 33;
       fhir:Element.id [ fhir:value "Observation.bodySite" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.bodySite" ];
       fhir:ElementDefinition.short [ fhir:value "Observed body part" ];
       fhir:ElementDefinition.definition [ fhir:value "Indicates the site on the subject's body where the observation was made (i.e. the target site)." ];
       fhir:ElementDefinition.comment [ fhir:value "Only used if not implicit in code found in Observation.code.  In many systems, this may be represented as a related observation instead of an inline component.   \n\nIf the use case requires BodySite to be handled as a separate resource (e.g. to identify and track separately) then use the standard extension[ bodySite](http://hl7.org/fhir/R4/extension-bodysite.html)." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.bodySite" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "BodySite" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes describing anatomical locations. May include laterality." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/body-site";
           fhir:link <http://hl7.org/fhir/ValueSet/body-site>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 123037004 |Body structure|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-20" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "targetSiteCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "718497002 |Inherent location|" ]       ]     ], [
       fhir:index 34;
       fhir:Element.id [ fhir:value "Observation.method" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.method" ];
       fhir:ElementDefinition.short [ fhir:value "Sequencing | SNP array | PCR | Computational analysis | ..." ];
       fhir:ElementDefinition.definition [ fhir:value "Indicates the mechanism used to perform the observation." ];
       fhir:ElementDefinition.comment [ fhir:value "Only used if not implicit in code for Observation.code." ];
       fhir:ElementDefinition.requirements [ fhir:value "In some cases, method can impact results and is thus used for determining whether results can be compared or determining significance of results." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.method" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL4048-6";
           fhir:link <http://loinc.org/vs/LL4048-6>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-17" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "methodCode" ]       ]     ], [
       fhir:index 35;
       fhir:Element.id [ fhir:value "Observation.specimen" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.specimen" ];
       fhir:ElementDefinition.short [ fhir:value "Specimen used for this observation" ];
       fhir:ElementDefinition.definition [ fhir:value "The specimen that was used when this observation was made." ];
       fhir:ElementDefinition.comment [ fhir:value "Should only be used if not implicit in code found in `Observation.code`.  Observations are not made on specimens themselves; they are made on a subject, but in many cases by the means of a specimen. Note that although specimens are often involved, they are not always tracked and reported explicitly. Also note that observation resources may be used in contexts that track the specimen explicitly (e.g. Diagnostic Report)." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.specimen" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ];
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Specimen";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Specimen>         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 123038009 |Specimen|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "SPM segment" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=SPC].specimen" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "704319004 |Inherent in|" ]       ]     ], [
       fhir:index 36;
       fhir:Element.id [ fhir:value "Observation.device" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.device" ];
       fhir:ElementDefinition.short [ fhir:value "(Measurement) Device" ];
       fhir:ElementDefinition.definition [ fhir:value "The device used to generate the observation data." ];
       fhir:ElementDefinition.comment [ fhir:value "Note that this is not meant to represent a device involved in the transmission of the result, e.g., a gateway.  Such devices may be documented using the Provenance resource where relevant." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.device" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ];
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Device";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Device>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DeviceMetric";
           fhir:index 1;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DeviceMetric>         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 49062001 |Device|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-17 / PRT -10" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "participation[typeCode=DEV]" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "424226004 |Using device|" ]       ]     ], [
       fhir:index 37;
       fhir:Element.id [ fhir:value "Observation.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range.  Multiple reference ranges are interpreted as an \"OR\".   In other words, to represent two distinct target populations, two `referenceRange` elements would be used." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "obs-3" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have at least a low or a high or text" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "low.exists() or high.exists() or text.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "(exists(f:low) or exists(f:high)or exists(f:text))" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Observation";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Observation>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 38;
       fhir:Element.id [ fhir:value "Observation.referenceRange.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 39;
       fhir:Element.id [ fhir:value "Observation.referenceRange.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 40;
       fhir:Element.id [ fhir:value "Observation.referenceRange.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 41;
       fhir:Element.id [ fhir:value "Observation.referenceRange.low" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.low" ];
       fhir:ElementDefinition.short [ fhir:value "Low Range, if relevant" ];
       fhir:ElementDefinition.definition [ fhir:value "The value of the low bound of the reference range.  The low bound of the reference range endpoint is inclusive of the value (e.g.  reference range is >=5 - <=9). If the low bound is omitted,  it is assumed to be meaningless (e.g. reference range is <=2.3)." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.low" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ];
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity>         ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-3";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value:IVL_PQ.low" ]       ]     ], [
       fhir:index 42;
       fhir:Element.id [ fhir:value "Observation.referenceRange.high" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.high" ];
       fhir:ElementDefinition.short [ fhir:value "High Range, if relevant" ];
       fhir:ElementDefinition.definition [ fhir:value "The value of the high bound of the reference range.  The high bound of the reference range endpoint is inclusive of the value (e.g.  reference range is >=5 - <=9). If the high bound is omitted,  it is assumed to be meaningless (e.g. reference range is >= 2.3)." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.high" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ];
         fhir:ElementDefinition.type.profile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/SimpleQuantity";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/SimpleQuantity>         ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-3";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value:IVL_PQ.high" ]       ]     ], [
       fhir:index 43;
       fhir:Element.id [ fhir:value "Observation.referenceRange.type" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.type" ];
       fhir:ElementDefinition.short [ fhir:value "Reference range qualifier" ];
       fhir:ElementDefinition.definition [ fhir:value "Codes to indicate the what part of the targeted reference population it applies to. For example, the normal or therapeutic range." ];
       fhir:ElementDefinition.comment [ fhir:value "This SHOULD be populated if there is more than one range.  If this element is not present then the normal range is assumed." ];
       fhir:ElementDefinition.requirements [ fhir:value "Need to be able to say what kind of reference range this is - normal, recommended, therapeutic, etc.,  - for proper interpretation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.type" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationRangeMeaning" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "preferred" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Code for the meaning of a reference range." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/referencerange-meaning";
           fhir:link <http://hl7.org/fhir/ValueSet/referencerange-meaning>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values| OR  \r< 365860008 |General clinical state finding| \rOR \r< 250171008 |Clinical history or observation findings| OR  \r< 415229000 |Racial group| OR \r< 365400002 |Finding of puberty stage| OR\r< 443938003 |Procedure carried out on subject|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-10" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ]     ], [
       fhir:index 44;
       fhir:Element.id [ fhir:value "Observation.referenceRange.appliesTo" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.appliesTo" ];
       fhir:ElementDefinition.short [ fhir:value "Reference range population" ];
       fhir:ElementDefinition.definition [ fhir:value "Codes to indicate the target population this reference range applies to.  For example, a reference range may be based on the normal population or a particular sex or race.  Multiple `appliesTo`  are interpreted as an \"AND\" of the target populations.  For example, to represent a target population of African American females, both a code of female and a code for African American would be used." ];
       fhir:ElementDefinition.comment [ fhir:value "This SHOULD be populated if there is more than one range.  If this element is not present then the normal population is assumed." ];
       fhir:ElementDefinition.requirements [ fhir:value "Need to be able to identify the target population for proper interpretation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.appliesTo" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationRangeType" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying the population the reference range applies to." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/referencerange-appliesto";
           fhir:link <http://hl7.org/fhir/ValueSet/referencerange-appliesto>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values| OR  \r< 365860008 |General clinical state finding| \rOR \r< 250171008 |Clinical history or observation findings| OR  \r< 415229000 |Racial group| OR \r< 365400002 |Finding of puberty stage| OR\r< 443938003 |Procedure carried out on subject|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-10" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ]     ], [
       fhir:index 45;
       fhir:Element.id [ fhir:value "Observation.referenceRange.age" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.age" ];
       fhir:ElementDefinition.short [ fhir:value "Applicable age range, if relevant" ];
       fhir:ElementDefinition.definition [ fhir:value "The age at which this reference range is applicable. This is a neonatal age (e.g. number of weeks at term) if the meaning says so." ];
       fhir:ElementDefinition.requirements [ fhir:value "Some analytes vary greatly over age." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.age" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=PRCN].targetObservationCriterion[code=\"age\"].value" ]       ]     ], [
       fhir:index 46;
       fhir:Element.id [ fhir:value "Observation.referenceRange.text" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.referenceRange.text" ];
       fhir:ElementDefinition.short [ fhir:value "Text based reference range in an observation" ];
       fhir:ElementDefinition.definition [ fhir:value "Text based reference range in an observation which may be used when a quantitative range is not appropriate for an observation.  An example would be a reference value of \"Negative\" or a list or table of \"normals\"." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.referenceRange.text" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value:ST" ]       ]     ], [
       fhir:index 47;
       fhir:Element.id [ fhir:value "Observation.hasMember" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.hasMember" ];
       fhir:ElementDefinition.short [ fhir:value "Related resource that belongs to the Observation group" ];
       fhir:ElementDefinition.definition [ fhir:value "This observation is a group observation (e.g. a battery, a panel of tests, a set of vital sign measurements) that includes the target as a member of the group." ];
       fhir:ElementDefinition.comment [ fhir:value "When using this element, an observation will typically have either a value or a set of related resources, although both may be present in some cases.  For a discussion on the ways Observations can assembled in groups together, see [Notes](http://hl7.org/fhir/R4/observation.html#obsgrouping) below.  Note that a system may calculate results from [QuestionnaireResponse](http://hl7.org/fhir/R4/questionnaireresponse.html)  into a final score and represent the score as an Observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.hasMember" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ];
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Observation";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Observation>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse";
           fhir:index 1;
           fhir:link <http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MolecularSequence";
           fhir:index 2;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MolecularSequence>         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Relationships established by OBX-4 usage" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship" ]       ]     ], [
       fhir:index 48;
       fhir:Element.id [ fhir:value "Observation.derivedFrom" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.derivedFrom" ];
       fhir:ElementDefinition.short [ fhir:value "Related measurements the observation is made from" ];
       fhir:ElementDefinition.definition [ fhir:value "The target resource that represents a measurement from which this observation value is derived. For example, a calculated anion gap or a fetal measurement based on an ultrasound image." ];
       fhir:ElementDefinition.comment [ fhir:value "All the reference choices that are listed in this element can represent clinical observations and other measurements that may be the source for a derived value.  The most common reference will be another Observation.  For a discussion on the ways Observations can assembled in groups together, see [Notes](http://hl7.org/fhir/R4/observation.html#obsgrouping) below." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.derivedFrom" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Reference" ];
         fhir:ElementDefinition.type.targetProfile [
           fhir:value "http://hl7.org/fhir/StructureDefinition/DocumentReference";
           fhir:index 0;
           fhir:link <http://hl7.org/fhir/StructureDefinition/DocumentReference>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/ImagingStudy";
           fhir:index 1;
           fhir:link <http://hl7.org/fhir/StructureDefinition/ImagingStudy>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Media";
           fhir:index 2;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Media>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse";
           fhir:index 3;
           fhir:link <http://hl7.org/fhir/StructureDefinition/QuestionnaireResponse>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Observation";
           fhir:index 4;
           fhir:link <http://hl7.org/fhir/StructureDefinition/Observation>         ], [
           fhir:value "http://hl7.org/fhir/StructureDefinition/MolecularSequence";
           fhir:index 5;
           fhir:link <http://hl7.org/fhir/StructureDefinition/MolecularSequence>         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "Relationships established by OBX-4 usage" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value ".targetObservation" ]       ]     ], [
       fhir:index 49;
       fhir:Element.id [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "pattern" ];
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "code" ]         ];
         fhir:ElementDefinition.slicing.description [ fhir:value "Slice based on the component.code pattern" ];
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]       ];
       fhir:ElementDefinition.short [ fhir:value "Component results" ];
       fhir:ElementDefinition.definition [ fhir:value "Some observations have multiple component observations.  These component observations are expressed as separate code value pairs that share the same attributes.  Examples include systolic and diastolic component observations for blood pressure measurement and multiple component observations for genetics observations." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 50;
       fhir:Element.id [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 51;
       fhir:Element.id [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 52;
       fhir:Element.id [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 53;
       fhir:Element.id [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "Type of component observation (code / type)" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 54;
       fhir:Element.id [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Actual component result" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.type.code [ fhir:value "boolean" ]       ], [
         fhir:index 4;
         fhir:ElementDefinition.type.code [ fhir:value "integer" ]       ], [
         fhir:index 5;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]       ], [
         fhir:index 6;
         fhir:ElementDefinition.type.code [ fhir:value "Ratio" ]       ], [
         fhir:index 7;
         fhir:ElementDefinition.type.code [ fhir:value "SampledData" ]       ], [
         fhir:index 8;
         fhir:ElementDefinition.type.code [ fhir:value "time" ]       ], [
         fhir:index 9;
         fhir:ElementDefinition.type.code [ fhir:value "dateTime" ]       ], [
         fhir:index 10;
         fhir:ElementDefinition.type.code [ fhir:value "Period" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 55;
       fhir:Element.id [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 56;
       fhir:Element.id [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 57;
       fhir:Element.id [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 58;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "conclusion-string" ];
       fhir:ElementDefinition.short [ fhir:value "Clinical Conclusion" ];
       fhir:ElementDefinition.definition [ fhir:value "Concise and clinically contextualized summary conclusion (interpretation/impression) of the observation" ];
       fhir:ElementDefinition.comment [ fhir:value "An example would be the interpretative information, typically canned, about a variant identified in the patient." ];
       fhir:ElementDefinition.requirements [ fhir:value "Need to be able to provide a conclusion that is not lost among the basic result data." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 59;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 60;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 61;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 62;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "conclusion-string" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ];
           fhir:Coding.code [ fhir:value "conclusion-string" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 63;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Summary conclusion (interpretation/impression)" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 64;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 65;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 66;
       fhir:Element.id [ fhir:value "Observation.component:conclusion-string.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 67;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "gene-studied" ];
       fhir:ElementDefinition.short [ fhir:value "Gene Studied" ];
       fhir:ElementDefinition.definition [ fhir:value "The gene(s) on which the variant is located." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 68;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 69;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 70;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 71;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48018-6" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48018-6;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48018-6" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 72;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "The HGNC gene symbol is to be used as display text and the HGNC gene ID used as the code. If no HGNC code issued for this gene yet, NCBI gene IDs SHALL be used." ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgnc-vs>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 73;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 74;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 75;
       fhir:Element.id [ fhir:value "Observation.component:gene-studied.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 76;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "cytogenetic-location" ];
       fhir:ElementDefinition.short [ fhir:value "Cytogenetic (Chromosome) Location" ];
       fhir:ElementDefinition.definition [ fhir:value "The relevant chromosomal region. The combination of numbers and letters provide a genetic 'address'." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 77;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 78;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 79;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 80;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48001-2" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48001-2;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48001-2" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 81;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Example: 1q21.1" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 82;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 83;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 84;
       fhir:Element.id [ fhir:value "Observation.component:cytogenetic-location.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 85;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "reference-sequence-assembly" ];
       fhir:ElementDefinition.short [ fhir:value "Human Reference Sequence Assembly" ];
       fhir:ElementDefinition.definition [ fhir:value "The reference genome/assembly used in this analysis." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 86;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 87;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 88;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 89;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "62374-4" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:62374-4;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "62374-4" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 90;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "GRCh37 | GRCh38 | ..." ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL1040-6";
           fhir:link <http://loinc.org/vs/LL1040-6>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 91;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 92;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 93;
       fhir:Element.id [ fhir:value "Observation.component:reference-sequence-assembly.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 94;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "coding-hgvs" ];
       fhir:ElementDefinition.short [ fhir:value "Coding (cDNA) Change - cHGVS" ];
       fhir:ElementDefinition.definition [ fhir:value "Description of the coding (cDNA) sequence change using a valid HGVS-formatted string." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 95;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 96;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 97;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 98;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48004-6" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48004-6;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48004-6" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 99;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'c.' string, e.g. NM_005228.5:c.2369C>T." ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 100;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 101;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 102;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 103;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-hgvs" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic (gDNA) Change - gHGVS" ];
       fhir:ElementDefinition.definition [ fhir:value "Description of the genomic (gDNA) sequence change using a valid HGVS-formatted string." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 104;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 105;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 106;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 107;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81290-9" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81290-9;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81290-9" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 108;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'g.' string, e.g. NC_000016.9:g.2124200_2138612dup" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 109;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 110;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 111;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 112;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "cytogenomic-nomenclature" ];
       fhir:ElementDefinition.short [ fhir:value "Cytogenomic Nomenclature (ISCN)" ];
       fhir:ElementDefinition.definition [ fhir:value "Fully describes a variant with a single code. Typically a large variant such as a mosaic, abnormal chromosome numbers, etc." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 113;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 114;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 115;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 116;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81291-7" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81291-7;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81291-7" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 117;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Actual component result" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 118;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 119;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 120;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 121;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-ref-seq" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic Reference Sequence" ];
       fhir:ElementDefinition.definition [ fhir:value "ID of the genomic reference sequence, which includes transcribed and non transcribed stretches" ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 122;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 123;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 124;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 125;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48013-7" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48013-7;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48013-7" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 126;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Versioned genomic reference sequence identifier" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable (NCBI or LRG)" ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 127;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 128;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 129;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 130;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "transcript-ref-seq" ];
       fhir:ElementDefinition.short [ fhir:value "Reference Transcript" ];
       fhir:ElementDefinition.definition [ fhir:value "NCBI's RefSeq ('NM_...'), Ensembl ('ENST...'), and LRG ('LRG...' plus 't1' to indicate transcript)" ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 131;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 132;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 133;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 134;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "51958-7" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:51958-7;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "51958-7" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 135;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Versioned transcript reference sequence identifier" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable (NCBI or LRG)" ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 136;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 137;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 138;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 139;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "exact-start-end" ];
       fhir:ElementDefinition.short [ fhir:value "Exact Start-End" ];
       fhir:ElementDefinition.definition [ fhir:value "The exact integer-based genomic coordinates of the start and end of the variant region." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 140;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 141;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 142;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 143;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81254-5" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81254-5;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81254-5" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 144;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Range in question. 'High' can be omitted for single nucleotide variants." ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 145;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 146;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 147;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 148;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "inner-start-end" ];
       fhir:ElementDefinition.short [ fhir:value "Inner Start-End" ];
       fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the narrowest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 149;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 150;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 151;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 152;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81302-2" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81302-2;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81302-2" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 153;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Imprecise variant inner-bounding range" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 154;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 155;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 156;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 157;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "outer-start-end" ];
       fhir:ElementDefinition.short [ fhir:value "Outer Start-End" ];
       fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the widest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 158;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 159;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 160;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 161;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81301-4" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81301-4;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81301-4" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 162;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Imprecise variant outer-bounding range" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 163;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 164;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 165;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 166;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "coordinate-system" ];
       fhir:ElementDefinition.short [ fhir:value "Coordinate System" ];
       fhir:ElementDefinition.definition [ fhir:value "These are different ways of identifying nucleotides or amino acids within a sequence. In the 1-based system, the first unit of the polymer (e.g. the first nucleotide) is counted as number 1. In the 0-based system, the number 0 designates the location before the first nucleotide. Different databases and file types may use different systems." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 167;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 168;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 169;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 170;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "92822-6" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:92822-6;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "92822-6" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 171;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "0-based interval counting | 0-based character counting | 1-based character counting" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL5323-2";
           fhir:link <http://loinc.org/vs/LL5323-2>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 172;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 173;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 174;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 175;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "ref-allele" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic Ref Allele" ];
       fhir:ElementDefinition.definition [ fhir:value "Reference values ('normal') examined within the Reference Sequence." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 176;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 177;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 178;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 179;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "69547-8" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:69547-8;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "69547-8" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 180;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Normalized string per the VCF format." ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 181;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 182;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 183;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 184;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "alt-allele" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic Alt Allele" ];
       fhir:ElementDefinition.definition [ fhir:value "The genomic alternate allele is the contiguous segment of DNA in the test sample that differs from the reference allele at the same location and thus defines a variant." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 185;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 186;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 187;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 188;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "69551-0" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:69551-0;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "69551-0" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 189;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Normalized string per the VCF format." ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 190;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 191;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 192;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 193;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "coding-change-type" ];
       fhir:ElementDefinition.short [ fhir:value "Coding DNA Change Type" ];
       fhir:ElementDefinition.definition [ fhir:value "Type of DNA change observed. Convenience property for variants with exact breakpoints, required otherwise." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 194;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 195;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 196;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 197;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48019-4" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48019-4;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48019-4" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 198;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "deletion | insertion | delins | SNV | copy_number_gain | copy_number_loss | ... (many)" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Concepts in sequence ontology under SO:0002072" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 199;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 200;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 201;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 202;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-source-class" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic Source Class" ];
       fhir:ElementDefinition.definition [ fhir:value "The genomic class of the specimen being analyzed: Germline for inherited genome, somatic for cancer genome, and prenatal for fetal genome." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 203;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 204;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 205;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 206;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48002-0" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48002-0;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48002-0" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 207;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Germline | Somatic | Fetal | Likely germline | Likely somatic | Likely fetal | Unknown genomic origin | De novo" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL378-1";
           fhir:link <http://loinc.org/vs/LL378-1>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 208;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 209;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 210;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 211;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "sample-allelic-frequency" ];
       fhir:ElementDefinition.short [ fhir:value "Sample Allelic Frequency" ];
       fhir:ElementDefinition.definition [ fhir:value "The relative frequency of the allele at a given locus in the sample." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 212;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 213;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 214;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 215;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81258-6" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81258-6;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81258-6" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 216;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Relative frequency in the sample" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 217;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 218;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].extension" ];
       fhir:ElementDefinition.slicing [
         fhir:ElementDefinition.slicing.discriminator [
           fhir:index 0;
           fhir:ElementDefinition.slicing.discriminator.type [ fhir:value "value" ];
           fhir:ElementDefinition.slicing.discriminator.path [ fhir:value "url" ]         ];
         fhir:ElementDefinition.slicing.description [ fhir:value "Extensions are always sliced by (at least) url" ];
         fhir:ElementDefinition.slicing.rules [ fhir:value "open" ]       ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 219;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].value" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].value" ];
       fhir:ElementDefinition.short [ fhir:value "Numerical value (with implicit precision)" ];
       fhir:ElementDefinition.definition [ fhir:value "The value of the measured amount. The value includes an implicit precision in the presentation of the value." ];
       fhir:ElementDefinition.comment [ fhir:value "The implicit precision in the value should always be honored. Monetary values have their own rules for handling precision (refer to standard accounting text books)." ];
       fhir:ElementDefinition.requirements [ fhir:value "Precision is handled implicitly in almost all cases of measurement." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Quantity.value" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "decimal" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "SN.2  / CQ - N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "PQ.value, CO.value, MO.value, IVL.high or IVL.low depending on the value" ]       ]     ], [
       fhir:index 220;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].comparator" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].comparator" ];
       fhir:ElementDefinition.short [ fhir:value "< | <= | >= | > - how to understand the value" ];
       fhir:ElementDefinition.definition [ fhir:value "How the value should be understood and represented - whether the actual value is greater or less than the stated value due to measurement issues; e.g. if the comparator is \"<\" , then the real value is < stated value." ];
       fhir:ElementDefinition.requirements [ fhir:value "Need a framework for handling measures where the value is <5ug/L or >400mg/L due to the limitations of measuring methodology." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Quantity.comparator" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "code" ]       ];
       fhir:ElementDefinition.meaningWhenMissing [ fhir:value "If there is no comparator, then there is no modification of the value" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "This is labeled as \"Is Modifier\" because the comparator modifies the interpretation of the value significantly. If there is no comparator, then there is no modification of the value" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "QuantityComparator" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.description [ fhir:value "How the Quantity should be understood and represented." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1";
           fhir:link <http://hl7.org/fhir/ValueSet/quantity-comparator|4.0.1>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "SN.1  / CQ.1" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "IVL properties" ]       ]     ], [
       fhir:index 221;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].unit" ];
       fhir:Element.extension [
         fhir:index 0;
         fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-translatable" ];
         fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]       ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].unit" ];
       fhir:ElementDefinition.short [ fhir:value "Unit representation" ];
       fhir:ElementDefinition.definition [ fhir:value "A human-readable form of the unit." ];
       fhir:ElementDefinition.requirements [ fhir:value "There are many representations for units of measure and in many contexts, particular representations are fixed and required. I.e. mcg for micrograms." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Quantity.unit" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "(see OBX.6 etc.) / CQ.2" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "PQ.unit" ]       ]     ], [
       fhir:index 222;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].system" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].system" ];
       fhir:ElementDefinition.short [ fhir:value "System that defines coded unit form" ];
       fhir:ElementDefinition.definition [ fhir:value "The identification of the system that provides the coded form of the unit." ];
       fhir:ElementDefinition.requirements [ fhir:value "Need to know the system that defines the coded form of the unit." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Quantity.system" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "uri" ]       ];
       fhir:ElementDefinition.patternUri [ fhir:value "http://unitsofmeasure.org" ];
       fhir:ElementDefinition.condition [
         fhir:value "qty-3";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "(see OBX.6 etc.) / CQ.2" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "CO.codeSystem, PQ.translation.codeSystem" ]       ]     ], [
       fhir:index 223;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].code" ];
       fhir:ElementDefinition.short [ fhir:value "Coded form of the unit" ];
       fhir:ElementDefinition.definition [ fhir:value "A computer processable form of the unit in some unit representation system." ];
       fhir:ElementDefinition.comment [ fhir:value "The preferred system is UCUM, but SNOMED CT can also be used (for customary units) or ISO 4217 for currency.  The context of use may additionally require a code from a particular system." ];
       fhir:ElementDefinition.requirements [ fhir:value "Need a computable form of the unit that is fixed across all forms. UCUM provides this for quantities, but SNOMED CT provides many units of interest." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Quantity.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "code" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "(see OBX.6 etc.) / CQ.2" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "PQ.code, MO.currency, PQ.translation.code" ]       ]     ], [
       fhir:index 224;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 225;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 226;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 227;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "allelic-read-depth" ];
       fhir:ElementDefinition.short [ fhir:value "Allelic Read Depth" ];
       fhir:ElementDefinition.definition [ fhir:value "Specifies the number of reads that identified the allele in question whether it consists of one or a small sequence of contiguous nucleotides. Different methods and purposes require different numbers of reads to be acceptable. Often >400, sometimes as few as 2-4." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 228;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 229;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 230;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 231;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "82121-5" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:82121-5;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "82121-5" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 232;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Unfiltered count of supporting reads" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 233;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 234;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 235;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 236;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "allelic-state" ];
       fhir:ElementDefinition.short [ fhir:value "Allelic State" ];
       fhir:ElementDefinition.definition [ fhir:value "The observed level of occurrence of the variant in the set of chromosomes." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 237;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 238;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 239;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 240;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "53034-5" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:53034-5;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "53034-5" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 241;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Heteroplasmic | Homoplasmic | Homozygous | Heterozygous | Hemizygous" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL381-5";
           fhir:link <http://loinc.org/vs/LL381-5>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 242;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 243;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 244;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 245;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "variant-inheritance" ];
       fhir:ElementDefinition.short [ fhir:value "Variant Inheritance" ];
       fhir:ElementDefinition.definition [ fhir:value "By which parent the variant was inherited in the patient, if known." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 246;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 247;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 248;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 249;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "variant-inheritance" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ];
           fhir:Coding.code [ fhir:value "variant-inheritance" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 250;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Maternal | Paternal | Unknown" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-inheritance-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-inheritance-vs>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 251;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 252;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 253;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 254;
       fhir:Element.id [ fhir:value "Observation.component:variation-code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "variation-code" ];
       fhir:ElementDefinition.short [ fhir:value "Variation Code" ];
       fhir:ElementDefinition.definition [ fhir:value "Accession number in a variant database such as ClinVar, given for cross-reference." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 255;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 256;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 257;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 258;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81252-9" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81252-9;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81252-9" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 259;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "ClinVar ID or similar" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable" ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 260;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 261;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 262;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 263;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "chromosome-identifier" ];
       fhir:ElementDefinition.short [ fhir:value "Chromosome Identifier" ];
       fhir:ElementDefinition.definition [ fhir:value "An indicator, enumerated in humans by numbers 1-22, X, and Y, representing the chromosome on which the variant is located." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 264;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 265;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 266;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 267;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48000-4" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48000-4;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48000-4" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 268;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Chromosome 1 | Chromosome 2 | ... | Chromosome 22 | Chromosome X | Chromosome Y" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL2938-0";
           fhir:link <http://loinc.org/vs/LL2938-0>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 269;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 270;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 271;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 272;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "protein-hgvs" ];
       fhir:ElementDefinition.short [ fhir:value "Protein (Amino Acid) Change - pHGVS" ];
       fhir:ElementDefinition.definition [ fhir:value "Description of the protein (amino acid) sequence change using a valid HGVS-formatted string. The description of the variant is surrounded in parentheses if it is calculated rather than directly observed." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 273;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 274;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 275;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 276;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48005-3" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48005-3;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48005-3" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 277;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'p.' string, e.g. NP_000050.2:p.(Asn1836Lys)" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 278;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 279;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 280;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 281;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "amino-acid-change-type" ];
       fhir:ElementDefinition.short [ fhir:value "Amino Acid Change Type" ];
       fhir:ElementDefinition.definition [ fhir:value "Codified type for associated Amino Acid Marker, for convenience." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 282;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 283;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 284;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 285;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48006-1" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48006-1;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48006-1" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 286;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Wild type | Deletion | Duplication | Frameshift | Initiating Methionine | Insertion | Insertion and Deletion | Missense | Nonsense | Silent" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL380-7";
           fhir:link <http://loinc.org/vs/LL380-7>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 287;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 288;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 289;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 290;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "molecular-consequence" ];
       fhir:ElementDefinition.short [ fhir:value "Molecular Consequence" ];
       fhir:ElementDefinition.definition [ fhir:value "The calculated or observed effect of a variant on its downstream transcript and, if applicable, ensuing protein sequence." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 291;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 292;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 293;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 294;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "molecular-consequence" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ];
           fhir:Coding.code [ fhir:value "molecular-consequence" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 295;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "stop_lost | stop_gained | inframe_insertion | frameshift_variant | ... (many)" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Concepts in sequence ontology under SO:0001537." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 296;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 297;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 298;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 299;
       fhir:Element.id [ fhir:value "Observation.component:copy-number" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "copy-number" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic Structural Variant Copy Number" ];
       fhir:ElementDefinition.definition [ fhir:value "The copy number of the large variant. In HGVS, this is the numeric value following the “X”. It is a unit-less value. Note that a copy number of 1 can imply a deletion." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 300;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 301;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 302;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 303;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "82155-3" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:82155-3;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "82155-3" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 304;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Actual component result" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "cnt-3" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "There SHALL be a code with a value of '1' if there is a value. If system is present, it SHALL be UCUM. If present, the value SHALL be a whole number." ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "(code.exists() or value.empty()) and (system.empty() or system = %ucum) and (code.empty() or code = '1') and (value.empty() or value.hasValue().not() or value.toString().contains('.').not())" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 305;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 306;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 307;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ], [
       fhir:index 308;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "variant-confidence-status" ];
       fhir:ElementDefinition.short [ fhir:value "Variant Confidence Status" ];
       fhir:ElementDefinition.definition [ fhir:value "A code that represents the confidence of a true positive variant call." ];
       fhir:ElementDefinition.comment [ fhir:value "For a discussion on the ways Observations can be assembled in groups together see [Notes](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "Component observations share the same attributes in the Observation resource as the primary observation and are always treated a part of a single observation (they are not separable).   However, the reference range for the primary observation value is not inherited by the component values and is required when appropriate for each component observation." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "BackboneElement" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "containment by OBX-4?" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outBoundRelationship[typeCode=COMP]" ]       ]     ], [
       fhir:index 309;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.id" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.id" ];
       fhir:ElementDefinition.representation [
         fhir:value "xmlAttr";
         fhir:index 0       ];
       fhir:ElementDefinition.short [ fhir:value "Unique id for inter-element referencing" ];
       fhir:ElementDefinition.definition [ fhir:value "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.id" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type" ];
           fhir:Extension.valueUrl [ fhir:value "string" ]         ];
         fhir:ElementDefinition.type.code [ fhir:value "http://hl7.org/fhirpath/System.String" ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 310;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.extension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.extension" ];
       fhir:ElementDefinition.short [ fhir:value "Additional content defined by implementations" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Element.extension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "n/a" ]       ]     ], [
       fhir:index 311;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.modifierExtension" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.modifierExtension" ];
       fhir:ElementDefinition.short [ fhir:value "Extensions that cannot be ignored even if unrecognized" ];
       fhir:ElementDefinition.definition [ fhir:value "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself)." ];
       fhir:ElementDefinition.comment [ fhir:value "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone." ];
       fhir:ElementDefinition.requirements [ fhir:value "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension)." ];
       fhir:ElementDefinition.alias [
         fhir:value "extensions";
         fhir:index 0       ], [
         fhir:value "user content";
         fhir:index 1       ], [
         fhir:value "modifiers";
         fhir:index 2       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "BackboneElement.modifierExtension" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Extension" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.constraint.key [ fhir:value "ext-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "Must have either extensions or value[x], not both" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "extension.exists() != value.exists()" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Extension";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Extension>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.isModifierReason [ fhir:value "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them" ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ]     ], [
       fhir:index 312;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "variant-confidence-status" ];
       fhir:ElementDefinition.definition [ fhir:value "Describes what was observed. Sometimes this is called the observation \"code\"." ];
       fhir:ElementDefinition.comment [ fhir:value "*All* code-value and  component.code-component.value pairs need to be taken into account to correctly understand the meaning of the observation." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what kind of observation is being made is essential to understanding the observation." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.code" ];
         fhir:ElementDefinition.base.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ];
           fhir:Coding.code [ fhir:value "variant-confidence-status" ]         ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationCode" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying names of simple observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-codes";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-codes>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "w5" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "FiveWs.what[x]" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 363787002 |Observable entity| OR \r< 386053000 |Evaluation procedure|" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-3" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "code" ]       ]     ], [
       fhir:index 313;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "High | Intermediate | Low" ];
       fhir:ElementDefinition.definition [ fhir:value "The information determined as a result of making the observation, if the information has a simple value." ];
       fhir:ElementDefinition.comment [ fhir:value "Used when observation has a set of component observations. An observation may have both a value (e.g. an  Apgar score)  and component observations (the observations from which the Apgar score was derived). If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value.  For additional guidance, see the [Notes section](http://hl7.org/fhir/R4/observation.html#notes) below." ];
       fhir:ElementDefinition.requirements [ fhir:value "An observation exists to have a value, though it might not if it is in error, or if it represents a group of observations." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.value[x]" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "true"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-confidence-status-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-confidence-status-vs>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets| < 441742003 |Evaluation finding|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.2, OBX.5, OBX.6" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363714003 |Interprets|" ]       ]     ], [
       fhir:index 314;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.dataAbsentReason" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.dataAbsentReason" ];
       fhir:ElementDefinition.short [ fhir:value "Why the component result is missing" ];
       fhir:ElementDefinition.definition [ fhir:value "Provides a reason why the expected value in the element Observation.component.value[x] is missing." ];
       fhir:ElementDefinition.comment [ fhir:value "\"Null\" or exceptional values can be represented two ways in FHIR Observations.  One way is to simply include them in the value set and represent the exceptions in the value.  For example, measurement values for a serology test could be  \"detected\", \"not detected\", \"inconclusive\", or  \"test not done\". \n\nThe alternate way is to use the value element for actual observations and use the explicit dataAbsentReason element to record exceptional values.  For example, the dataAbsentReason code \"error\" could be used when the measurement was not completed.  Because of these options, use-case agreements are required to interpret general observations for exceptional values." ];
       fhir:ElementDefinition.requirements [ fhir:value "For many results it is necessary to handle exceptional values in measurements." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.dataAbsentReason" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "1" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.condition [
         fhir:value "obs-6";
         fhir:index 0       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationValueAbsentReason" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes specifying why the result (`Observation.value[x]`) is missing." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/data-absent-reason";
           fhir:link <http://hl7.org/fhir/ValueSet/data-absent-reason>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "N/A" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "value.nullFlavor" ]       ]     ], [
       fhir:index 315;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.interpretation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.interpretation" ];
       fhir:ElementDefinition.short [ fhir:value "High, low, normal, etc." ];
       fhir:ElementDefinition.definition [ fhir:value "A categorical assessment of an observation value.  For example, high, low, normal." ];
       fhir:ElementDefinition.comment [ fhir:value "Historically used for laboratory results (known as 'abnormal flag' ),  its use extends to other use cases where coded interpretations  are relevant.  Often reported as one or more simple compact codes this element is often placed adjacent to the result value in reports and flow sheets to signal the meaning/normalcy status of the result." ];
       fhir:ElementDefinition.requirements [ fhir:value "For some results, particularly numeric results, an interpretation is necessary to fully understand the significance of a result." ];
       fhir:ElementDefinition.alias [
         fhir:value "Abnormal Flag";
         fhir:index 0       ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.interpretation" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.binding [
         fhir:Element.extension [
           fhir:index 0;
           fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName" ];
           fhir:Extension.valueString [ fhir:value "ObservationInterpretation" ]         ];
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Codes identifying interpretations of observations." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/ValueSet/observation-interpretation";
           fhir:link <http://hl7.org/fhir/ValueSet/observation-interpretation>         ]       ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-concept" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "< 260245000 |Findings values|" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX-8" ]       ], [
         fhir:index 2;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "interpretationCode" ]       ], [
         fhir:index 3;
         fhir:ElementDefinition.mapping.identity [ fhir:value "sct-attr" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "363713009 |Has interpretation|" ]       ]     ], [
       fhir:index 316;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.referenceRange" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.referenceRange" ];
       fhir:ElementDefinition.short [ fhir:value "Provides guide for interpretation of component result" ];
       fhir:ElementDefinition.definition [ fhir:value "Guidance on how to interpret the value by comparison to a normal or recommended range." ];
       fhir:ElementDefinition.comment [ fhir:value "Most observations only have one generic reference range. Systems MAY choose to restrict to only supplying the relevant reference range based on knowledge about the patient (e.g., specific to the patient's age, gender, weight and other factors), but this might not be possible or appropriate. Whenever more than one reference range is supplied, the differences between them SHOULD be provided in the reference range and/or age properties." ];
       fhir:ElementDefinition.requirements [ fhir:value "Knowing what values are considered \"normal\" can help evaluate the significance of a particular result. Need to be able to provide multiple reference ranges for different contexts." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ];
       fhir:ElementDefinition.base [
         fhir:ElementDefinition.base.path [ fhir:value "Observation.component.referenceRange" ];
         fhir:ElementDefinition.base.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
         fhir:ElementDefinition.base.max [ fhir:value "*" ]       ];
       fhir:ElementDefinition.contentReference [ fhir:value "http://hl7.org/fhir/StructureDefinition/Observation#Observation.referenceRange" ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "ele-1" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "All FHIR elements must have a @value or children" ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "hasValue() or (children().count() > id.count())" ];
         fhir:ElementDefinition.constraint.xpath [ fhir:value "@value|f:*|h:div" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/StructureDefinition/Element";
           fhir:link <http://hl7.org/fhir/StructureDefinition/Element>         ]       ];
       fhir:ElementDefinition.isModifier [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.isSummary [ fhir:value "false"^^xsd:boolean ];
       fhir:ElementDefinition.mapping [
         fhir:index 0;
         fhir:ElementDefinition.mapping.identity [ fhir:value "v2" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "OBX.7" ]       ], [
         fhir:index 1;
         fhir:ElementDefinition.mapping.identity [ fhir:value "rim" ];
         fhir:ElementDefinition.mapping.map [ fhir:value "outboundRelationship[typeCode=REFV]/target[classCode=OBS, moodCode=EVN]" ]       ]     ]
  ];
  fhir:StructureDefinition.differential [
     fhir:StructureDefinition.differential.element [
       fhir:index 0;
       fhir:Element.id [ fhir:value "Observation" ];
       fhir:ElementDefinition.path [ fhir:value "Observation" ];
       fhir:ElementDefinition.short [ fhir:value "Variant" ]     ], [
       fhir:index 1;
       fhir:Element.id [ fhir:value "Observation.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.code" ];
       fhir:ElementDefinition.short [ fhir:value "69548-6" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:69548-6;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "69548-6" ]         ]       ]     ], [
       fhir:index 2;
       fhir:Element.id [ fhir:value "Observation.valueCodeableConcept" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.valueCodeableConcept" ];
       fhir:ElementDefinition.short [ fhir:value "Indeterminate | No call | Present | Absent." ];
       fhir:ElementDefinition.definition [ fhir:value "The presence or absence of the variant described in the components. If not searching for specific variations and merely reporting what's found, the profile's value should be set to 'Present'." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL1971-2";
           fhir:link <http://loinc.org/vs/LL1971-2>         ]       ]     ], [
       fhir:index 3;
       fhir:Element.id [ fhir:value "Observation.method" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.method" ];
       fhir:ElementDefinition.short [ fhir:value "Sequencing | SNP array | PCR | Computational analysis | ..." ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL4048-6";
           fhir:link <http://loinc.org/vs/LL4048-6>         ]       ]     ], [
       fhir:index 4;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "coding-hgvs" ];
       fhir:ElementDefinition.short [ fhir:value "Coding (cDNA) Change - cHGVS" ];
       fhir:ElementDefinition.definition [ fhir:value "Description of the coding (cDNA) sequence change using a valid HGVS-formatted string." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 5;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48004-6" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48004-6;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48004-6" ]         ]       ]     ], [
       fhir:index 6;
       fhir:Element.id [ fhir:value "Observation.component:coding-hgvs.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'c.' string, e.g. NM_005228.5:c.2369C>T." ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>         ]       ]     ], [
       fhir:index 7;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-hgvs" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic (gDNA) Change - gHGVS" ];
       fhir:ElementDefinition.definition [ fhir:value "Description of the genomic (gDNA) sequence change using a valid HGVS-formatted string." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 8;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81290-9" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81290-9;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81290-9" ]         ]       ]     ], [
       fhir:index 9;
       fhir:Element.id [ fhir:value "Observation.component:genomic-hgvs.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'g.' string, e.g. NC_000016.9:g.2124200_2138612dup" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>         ]       ]     ], [
       fhir:index 10;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "cytogenomic-nomenclature" ];
       fhir:ElementDefinition.short [ fhir:value "Cytogenomic Nomenclature (ISCN)" ];
       fhir:ElementDefinition.definition [ fhir:value "Fully describes a variant with a single code. Typically a large variant such as a mosaic, abnormal chromosome numbers, etc." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 11;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81291-7" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81291-7;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81291-7" ]         ]       ]     ], [
       fhir:index 12;
       fhir:Element.id [ fhir:value "Observation.component:cytogenomic-nomenclature.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Binding not yet defined" ]       ]     ], [
       fhir:index 13;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-ref-seq" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic Reference Sequence" ];
       fhir:ElementDefinition.definition [ fhir:value "ID of the genomic reference sequence, which includes transcribed and non transcribed stretches" ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 14;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48013-7" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48013-7;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48013-7" ]         ]       ]     ], [
       fhir:index 15;
       fhir:Element.id [ fhir:value "Observation.component:genomic-ref-seq.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Versioned genomic reference sequence identifier" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable (NCBI or LRG)" ]       ]     ], [
       fhir:index 16;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "transcript-ref-seq" ];
       fhir:ElementDefinition.short [ fhir:value "Reference Transcript" ];
       fhir:ElementDefinition.definition [ fhir:value "NCBI's RefSeq ('NM_...'), Ensembl ('ENST...'), and LRG ('LRG...' plus 't1' to indicate transcript)" ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 17;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "51958-7" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:51958-7;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "51958-7" ]         ]       ]     ], [
       fhir:index 18;
       fhir:Element.id [ fhir:value "Observation.component:transcript-ref-seq.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Versioned transcript reference sequence identifier" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable (NCBI or LRG)" ]       ]     ], [
       fhir:index 19;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "exact-start-end" ];
       fhir:ElementDefinition.short [ fhir:value "Exact Start-End" ];
       fhir:ElementDefinition.definition [ fhir:value "The exact integer-based genomic coordinates of the start and end of the variant region." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 20;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81254-5" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81254-5;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81254-5" ]         ]       ]     ], [
       fhir:index 21;
       fhir:Element.id [ fhir:value "Observation.component:exact-start-end.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Range in question. 'High' can be omitted for single nucleotide variants." ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]       ]     ], [
       fhir:index 22;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "inner-start-end" ];
       fhir:ElementDefinition.short [ fhir:value "Inner Start-End" ];
       fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the narrowest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 23;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81302-2" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81302-2;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81302-2" ]         ]       ]     ], [
       fhir:index 24;
       fhir:Element.id [ fhir:value "Observation.component:inner-start-end.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Imprecise variant inner-bounding range" ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]       ]     ], [
       fhir:index 25;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "outer-start-end" ];
       fhir:ElementDefinition.short [ fhir:value "Outer Start-End" ];
       fhir:ElementDefinition.definition [ fhir:value "The genomic coordinates of the widest genomic range in which the variant might reside. Used when the exact boundaries of the variant are not clear." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 26;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81301-4" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81301-4;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81301-4" ]         ]       ]     ], [
       fhir:index 27;
       fhir:Element.id [ fhir:value "Observation.component:outer-start-end.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Imprecise variant outer-bounding range" ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Range" ]       ]     ], [
       fhir:index 28;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "coordinate-system" ];
       fhir:ElementDefinition.short [ fhir:value "Coordinate System" ];
       fhir:ElementDefinition.definition [ fhir:value "These are different ways of identifying nucleotides or amino acids within a sequence. In the 1-based system, the first unit of the polymer (e.g. the first nucleotide) is counted as number 1. In the 0-based system, the number 0 designates the location before the first nucleotide. Different databases and file types may use different systems." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 29;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "92822-6" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:92822-6;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "92822-6" ]         ]       ]     ], [
       fhir:index 30;
       fhir:Element.id [ fhir:value "Observation.component:coordinate-system.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "0-based interval counting | 0-based character counting | 1-based character counting" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL5323-2";
           fhir:link <http://loinc.org/vs/LL5323-2>         ]       ]     ], [
       fhir:index 31;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "ref-allele" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic Ref Allele" ];
       fhir:ElementDefinition.definition [ fhir:value "Reference values ('normal') examined within the Reference Sequence." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 32;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "69547-8" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:69547-8;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "69547-8" ]         ]       ]     ], [
       fhir:index 33;
       fhir:Element.id [ fhir:value "Observation.component:ref-allele.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Normalized string per the VCF format." ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]       ]     ], [
       fhir:index 34;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "alt-allele" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic Alt Allele" ];
       fhir:ElementDefinition.definition [ fhir:value "The genomic alternate allele is the contiguous segment of DNA in the test sample that differs from the reference allele at the same location and thus defines a variant." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 35;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "69551-0" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:69551-0;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "69551-0" ]         ]       ]     ], [
       fhir:index 36;
       fhir:Element.id [ fhir:value "Observation.component:alt-allele.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Normalized string per the VCF format." ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "string" ]       ]     ], [
       fhir:index 37;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "coding-change-type" ];
       fhir:ElementDefinition.short [ fhir:value "Coding DNA Change Type" ];
       fhir:ElementDefinition.definition [ fhir:value "Type of DNA change observed. Convenience property for variants with exact breakpoints, required otherwise." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 38;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48019-4" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48019-4;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48019-4" ]         ]       ]     ], [
       fhir:index 39;
       fhir:Element.id [ fhir:value "Observation.component:coding-change-type.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "deletion | insertion | delins | SNV | copy_number_gain | copy_number_loss | ... (many)" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Concepts in sequence ontology under SO:0002072" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/dna-change-type-vs>         ]       ]     ], [
       fhir:index 40;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "genomic-source-class" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic Source Class" ];
       fhir:ElementDefinition.definition [ fhir:value "The genomic class of the specimen being analyzed: Germline for inherited genome, somatic for cancer genome, and prenatal for fetal genome." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 41;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48002-0" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48002-0;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48002-0" ]         ]       ]     ], [
       fhir:index 42;
       fhir:Element.id [ fhir:value "Observation.component:genomic-source-class.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Germline | Somatic | Fetal | Likely germline | Likely somatic | Likely fetal | Unknown genomic origin | De novo" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL378-1";
           fhir:link <http://loinc.org/vs/LL378-1>         ]       ]     ], [
       fhir:index 43;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "sample-allelic-frequency" ];
       fhir:ElementDefinition.short [ fhir:value "Sample Allelic Frequency" ];
       fhir:ElementDefinition.definition [ fhir:value "The relative frequency of the allele at a given locus in the sample." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 44;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81258-6" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81258-6;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81258-6" ]         ]       ]     ], [
       fhir:index 45;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Relative frequency in the sample" ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]       ]     ], [
       fhir:index 46;
       fhir:Element.id [ fhir:value "Observation.component:sample-allelic-frequency.value[x].system" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x].system" ];
       fhir:ElementDefinition.patternUri [ fhir:value "http://unitsofmeasure.org" ]     ], [
       fhir:index 47;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "allelic-read-depth" ];
       fhir:ElementDefinition.short [ fhir:value "Allelic Read Depth" ];
       fhir:ElementDefinition.definition [ fhir:value "Specifies the number of reads that identified the allele in question whether it consists of one or a small sequence of contiguous nucleotides. Different methods and purposes require different numbers of reads to be acceptable. Often >400, sometimes as few as 2-4." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 48;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "82121-5" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:82121-5;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "82121-5" ]         ]       ]     ], [
       fhir:index 49;
       fhir:Element.id [ fhir:value "Observation.component:allelic-read-depth.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Unfiltered count of supporting reads" ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]       ]     ], [
       fhir:index 50;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "allelic-state" ];
       fhir:ElementDefinition.short [ fhir:value "Allelic State" ];
       fhir:ElementDefinition.definition [ fhir:value "The observed level of occurrence of the variant in the set of chromosomes." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 51;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "53034-5" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:53034-5;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "53034-5" ]         ]       ]     ], [
       fhir:index 52;
       fhir:Element.id [ fhir:value "Observation.component:allelic-state.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Heteroplasmic | Homoplasmic | Homozygous | Heterozygous | Hemizygous" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL381-5";
           fhir:link <http://loinc.org/vs/LL381-5>         ]       ]     ], [
       fhir:index 53;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "variant-inheritance" ];
       fhir:ElementDefinition.short [ fhir:value "Variant Inheritance" ];
       fhir:ElementDefinition.definition [ fhir:value "By which parent the variant was inherited in the patient, if known." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 54;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "variant-inheritance" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ];
           fhir:Coding.code [ fhir:value "variant-inheritance" ]         ]       ]     ], [
       fhir:index 55;
       fhir:Element.id [ fhir:value "Observation.component:variant-inheritance.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Maternal | Paternal | Unknown" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-inheritance-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-inheritance-vs>         ]       ]     ], [
       fhir:index 56;
       fhir:Element.id [ fhir:value "Observation.component:variation-code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "variation-code" ];
       fhir:ElementDefinition.short [ fhir:value "Variation Code" ];
       fhir:ElementDefinition.definition [ fhir:value "Accession number in a variant database such as ClinVar, given for cross-reference." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ]     ], [
       fhir:index 57;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "81252-9" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:81252-9;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "81252-9" ]         ]       ]     ], [
       fhir:index 58;
       fhir:Element.id [ fhir:value "Observation.component:variation-code.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "ClinVar ID or similar" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "example" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Multiple bindings acceptable" ]       ]     ], [
       fhir:index 59;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "chromosome-identifier" ];
       fhir:ElementDefinition.short [ fhir:value "Chromosome Identifier" ];
       fhir:ElementDefinition.definition [ fhir:value "An indicator, enumerated in humans by numbers 1-22, X, and Y, representing the chromosome on which the variant is located." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "*" ]     ], [
       fhir:index 60;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48000-4" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48000-4;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48000-4" ]         ]       ]     ], [
       fhir:index 61;
       fhir:Element.id [ fhir:value "Observation.component:chromosome-identifier.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Chromosome 1 | Chromosome 2 | ... | Chromosome 22 | Chromosome X | Chromosome Y" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL2938-0";
           fhir:link <http://loinc.org/vs/LL2938-0>         ]       ]     ], [
       fhir:index 62;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "protein-hgvs" ];
       fhir:ElementDefinition.short [ fhir:value "Protein (Amino Acid) Change - pHGVS" ];
       fhir:ElementDefinition.definition [ fhir:value "Description of the protein (amino acid) sequence change using a valid HGVS-formatted string. The description of the variant is surrounded in parentheses if it is calculated rather than directly observed." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 63;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48005-3" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48005-3;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48005-3" ]         ]       ]     ], [
       fhir:index 64;
       fhir:Element.id [ fhir:value "Observation.component:protein-hgvs.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "A valid HGVS-formatted 'p.' string, e.g. NP_000050.2:p.(Asn1836Lys)" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/hgvs-vs>         ]       ]     ], [
       fhir:index 65;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "amino-acid-change-type" ];
       fhir:ElementDefinition.short [ fhir:value "Amino Acid Change Type" ];
       fhir:ElementDefinition.definition [ fhir:value "Codified type for associated Amino Acid Marker, for convenience." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 66;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "48006-1" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:48006-1;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "48006-1" ]         ]       ]     ], [
       fhir:index 67;
       fhir:Element.id [ fhir:value "Observation.component:amino-acid-change-type.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "Wild type | Deletion | Duplication | Frameshift | Initiating Methionine | Insertion | Insertion and Deletion | Missense | Nonsense | Silent" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://loinc.org/vs/LL380-7";
           fhir:link <http://loinc.org/vs/LL380-7>         ]       ]     ], [
       fhir:index 68;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "molecular-consequence" ];
       fhir:ElementDefinition.short [ fhir:value "Molecular Consequence" ];
       fhir:ElementDefinition.definition [ fhir:value "The calculated or observed effect of a variant on its downstream transcript and, if applicable, ensuing protein sequence." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 69;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "molecular-consequence" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ];
           fhir:Coding.code [ fhir:value "molecular-consequence" ]         ]       ]     ], [
       fhir:index 70;
       fhir:Element.id [ fhir:value "Observation.component:molecular-consequence.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "stop_lost | stop_gained | inframe_insertion | frameshift_variant | ... (many)" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "extensible" ];
         fhir:ElementDefinition.binding.description [ fhir:value "Concepts in sequence ontology under SO:0001537." ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/molecular-consequence-vs>         ]       ]     ], [
       fhir:index 71;
       fhir:Element.id [ fhir:value "Observation.component:copy-number" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "copy-number" ];
       fhir:ElementDefinition.short [ fhir:value "Genomic Structural Variant Copy Number" ];
       fhir:ElementDefinition.definition [ fhir:value "The copy number of the large variant. In HGVS, this is the numeric value following the “X”. It is a unit-less value. Note that a copy number of 1 can imply a deletion." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 72;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "82155-3" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a loinc:82155-3;
           fhir:Coding.system [ fhir:value "http://loinc.org" ];
           fhir:Coding.code [ fhir:value "82155-3" ]         ]       ]     ], [
       fhir:index 73;
       fhir:Element.id [ fhir:value "Observation.component:copy-number.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "Quantity" ]       ];
       fhir:ElementDefinition.constraint [
         fhir:index 0;
         fhir:ElementDefinition.constraint.key [ fhir:value "cnt-3" ];
         fhir:ElementDefinition.constraint.severity [ fhir:value "error" ];
         fhir:ElementDefinition.constraint.human [ fhir:value "There SHALL be a code with a value of '1' if there is a value. If system is present, it SHALL be UCUM. If present, the value SHALL be a whole number." ];
         fhir:ElementDefinition.constraint.expression [ fhir:value "(code.exists() or value.empty()) and (system.empty() or system = %ucum) and (code.empty() or code = '1') and (value.empty() or value.hasValue().not() or value.toString().contains('.').not())" ];
         fhir:ElementDefinition.constraint.source [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant>         ]       ]     ], [
       fhir:index 74;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component" ];
       fhir:ElementDefinition.sliceName [ fhir:value "variant-confidence-status" ];
       fhir:ElementDefinition.short [ fhir:value "Variant Confidence Status" ];
       fhir:ElementDefinition.definition [ fhir:value "A code that represents the confidence of a true positive variant call." ];
       fhir:ElementDefinition.min [ fhir:value "0"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.max [ fhir:value "1" ]     ], [
       fhir:index 75;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.code" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.code" ];
       fhir:ElementDefinition.short [ fhir:value "variant-confidence-status" ];
       fhir:ElementDefinition.patternCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs" ];
           fhir:Coding.code [ fhir:value "variant-confidence-status" ]         ]       ]     ], [
       fhir:index 76;
       fhir:Element.id [ fhir:value "Observation.component:variant-confidence-status.value[x]" ];
       fhir:ElementDefinition.path [ fhir:value "Observation.component.value[x]" ];
       fhir:ElementDefinition.short [ fhir:value "High | Intermediate | Low" ];
       fhir:ElementDefinition.min [ fhir:value "1"^^xsd:nonNegativeInteger ];
       fhir:ElementDefinition.type [
         fhir:index 0;
         fhir:ElementDefinition.type.code [ fhir:value "CodeableConcept" ]       ];
       fhir:ElementDefinition.binding [
         fhir:ElementDefinition.binding.strength [ fhir:value "required" ];
         fhir:ElementDefinition.binding.valueSet [
           fhir:value "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-confidence-status-vs";
           fhir:link <http://hl7.org/fhir/uv/genomics-reporting/ValueSet/variant-confidence-status-vs>         ]       ]     ]
  ].

# - ontology header ------------------------------------------------------------

 a owl:Ontology;
  owl:imports fhir:fhir.ttl.