tbd-codes-cs vs tbd-codes-cs

CodeSystem Comparison between http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs vs http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs

Messages

Error

CodeSystem.version

Values for version differ: '2.0.0' vs '3.0.0-ballot'

Information

CodeSystem.date

Values for date differ: '2022-05-09T16:53:07+00:00' vs '2023-12-18T22:45:59+00:00'

Information

CodeSystem.publisher

Values for publisher differ: 'HL7 Clinical Genomics Working Group' vs 'HL7 International / Clinical Genomics'

Information

CodeSystem.concept.where(code='molecular-consequence').definition

Changed value for definition: 'Annotated changes to sequence features caused by this variant. Terms are from the sequence ontology under SO:0001537. The calculated or observed effect of a variant on its downstream transcript and, if applicable, ensuing protein sequence.' vs 'The calculated or observed effect of a DNA variant on its downstream transcript and, if applicable, ensuing protein sequence.'

Information

CodeSystem.concept.where(code='therapeutic-implication').definition

Changed value for definition: 'An observation linking a genomic finding with a knowledge base, providing potential evidence of an interaction with a specified medication or non-medicinal therapy.' vs 'An observation linking a genomic finding with a knowledge base, providing potential evidence of an interaction with a specified medication or non-medicinal therapy. Ramifications may include alterations in drug metabolism (or pharmacokinetics) that determine the concentration of the drug, prodrug, and/or break-down products over time; alterations in drug efficacy (or pharmacodynamics) that determine how effective a drug is at a given concentration; alterations that alter the risk of adverse drug events, or other types of implications that indicate altered responsiveness to other types of therapies.'

Metadata

Name	Value	Comments
caseSensitive	true
compositional
content	complete
copyright
date	2022-05-09T16:53:07+00:00	2023-12-18T22:45:59+00:00	Values Differ
description	These codes are currently 'TBD' codes. The CG WG plans to request formal LOINC codes to replace these codes as these concepts are validated.
experimental		false	Added the item 'false'
hierarchyMeaning
jurisdiction
jurisdiction[0]	http://unstats.un.org/unsd/methods/m49/m49.htm#001
name	TbdCodesCS
publisher	HL7 Clinical Genomics Working Group	HL7 International / Clinical Genomics	Values Differ
purpose
status	active
title	To Be Determined Codes
url	http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs
version	2.0.0	3.0.0-ballot	Values Differ
versionNeeded

Name

Value

Comments

caseSensitive

true

compositional

content

complete

date

2022-05-09T16:53:07+00:00

2023-12-18T22:45:59+00:00

Values Differ

description

These codes are currently 'TBD' codes. The CG WG plans to request formal LOINC codes to replace these codes as these concepts are validated.

experimental

false

Added the item 'false'

hierarchyMeaning

jurisdiction

jurisdiction[0]

http://unstats.un.org/unsd/methods/m49/m49.htm#001

name

TbdCodesCS

publisher

HL7 Clinical Genomics Working Group

HL7 International / Clinical Genomics

Values Differ

purpose

status

active

title

To Be Determined Codes

url

http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs

version

2.0.0

3.0.0-ballot

Values Differ

versionNeeded

Concepts

Code	Display	Comments
predicted-therapeutic-implication	Predicted Therapeutic Implication		Removed this concept
prognostic-implication	Prognostic Implication		Removed this concept
associated-therapy	Associated Therapy
region-coverage	Region Coverage		Removed this concept
molecular-consequence	Molecular Consequence	definition changed from left to right
variant-inheritance	Variant Inheritance		Removed this concept
diagnostic-implication	Diagnostic Implication
therapeutic-implication	Therapeutic Implication	definition changed from left to right
uncallable-regions	Uncallable Regions		Removed this concept
functional-effect	Functional Effect
conclusion-string	Conclusion Text
condition-inheritance	Condition Inheritance
variant-confidence-status	Variant Confidence Status
feature-consequence		Feature Consequence	Added this concept
repeat-motif		Repeat Expansion Motif	Added this concept
repeat-number		Number of Repeat Expansions	Added this concept
biomarker-category		A characterization of a given biomarker observation.	Added this concept
protein-ref-seq		An identifier for the protein reference sequence.	Added this concept

Code

Display

Comments

predicted-therapeutic-implication

Predicted Therapeutic Implication

Removed this concept

prognostic-implication

Prognostic Implication

Removed this concept

associated-therapy

Associated Therapy

region-coverage

Region Coverage

Removed this concept

molecular-consequence

Molecular Consequence

definition changed from left to right

variant-inheritance

Variant Inheritance

Removed this concept

diagnostic-implication

Diagnostic Implication

therapeutic-implication

Therapeutic Implication

definition changed from left to right

uncallable-regions

Uncallable Regions

Removed this concept

functional-effect

Functional Effect

conclusion-string

Conclusion Text

condition-inheritance

Condition Inheritance

variant-confidence-status

Variant Confidence Status

feature-consequence

Feature Consequence

Added this concept

repeat-motif

Repeat Expansion Motif

Added this concept

repeat-number

Number of Repeat Expansions

Added this concept

biomarker-category

A characterization of a given biomarker observation.

Added this concept

protein-ref-seq

An identifier for the protein reference sequence.

Added this concept