Genomics Reporting Implementation Guide
3.0.0-ballot - Ballot International flag

This page is part of the Genetic Reporting Implementation Guide (v3.0.0-ballot: STU 3 Ballot 1) based on FHIR (HL7® FHIR® Standard) R4. The current version which supersedes this version is 2.0.0. For a full list of available versions, see the Directory of published versions

: High Low codes - JSON Representation

Active as of 2023-12-18

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{
  "resourceType" : "ValueSet",
  "id" : "high-low-codes-vs",
  "text" : {
    "status" : "extensions",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><ul><li>Include these codes as defined in <a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ObservationInterpretation.html\"><code>http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation</code></a><table class=\"none\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td><a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ObservationInterpretation.html#v3-ObservationInterpretation-H\">H</a></td><td>High</td><td>The result for a quantitative observation is above the upper limit of the reference range (as defined for the respective test procedure).<br/><br/>Synonym: Above high normal</td></tr><tr><td><a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ObservationInterpretation.html#v3-ObservationInterpretation-L\">L</a></td><td>Low</td><td>The result for a quantitative observation is below the lower limit of the reference range (as defined for the respective test procedure).<br/><br/>Synonym: Below low normal</td></tr><tr><td><a href=\"http://terminology.hl7.org/5.3.0/CodeSystem-v3-ObservationInterpretation.html#v3-ObservationInterpretation-I\">I</a></td><td>Intermediate</td><td>Bacterial strain inhibited in vitro by a concentration of an antimicrobial agent that is associated with uncertain therapeutic effect. Reference: CLSI (http://www.clsi.org/Content/NavigationMenu/Resources/HarmonizedTerminologyDatabase/Harmonized\\_Terminolo.htm) Projects: ISO 20776-1, ISO 20776-2<br/><br/>\\[Note 1: Bacterial strains are categorized as intermediate by applying the appropriate breakpoints in a defined phenotypic test system.\\]<br/><br/>\\[Note 2: This class of susceptibility implies that an infection due to the isolate can be appropriately treated in body sites where the drugs are physiologically concentrated or when a high dosage of drug can be used.\\]<br/><br/>\\[Note 3: This class also indicates a &quot;buffer zone,&quot; to prevent small, uncontrolled, technical factors from causing major discrepancies in interpretations.\\]<br/><br/>\\[Note 4: These breakpoints can be altered due to changes in circumstances (e.g., changes in commonly used drug dosages, emergence of new resistance mechanisms).\\]</td></tr></table></li></ul></div>"
  },
  "extension" : [
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
      "valueCode" : "cg"
    }
  ],
  "url" : "http://hl7.org/fhir/uv/genomics-reporting/ValueSet/high-low-codes-vs",
  "version" : "3.0.0-ballot",
  "name" : "HighLowCodesVS",
  "title" : "High Low codes",
  "status" : "active",
  "experimental" : false,
  "date" : "2023-12-18T22:45:59+00:00",
  "publisher" : "HL7 International / Clinical Genomics",
  "contact" : [
    {
      "name" : "HL7 International / Clinical Genomics",
      "telecom" : [
        {
          "system" : "url",
          "value" : "http://www.hl7.org/Special/committees/clingenomics"
        },
        {
          "system" : "email",
          "value" : "cg@lists.HL7.org"
        }
      ]
    }
  ],
  "description" : "This value set includes high/low codes for Observation Interpretations",
  "jurisdiction" : [
    {
      "coding" : [
        {
          "system" : "http://unstats.un.org/unsd/methods/m49/m49.htm",
          "code" : "001",
          "display" : "World"
        }
      ]
    }
  ],
  "compose" : {
    "include" : [
      {
        "system" : "http://terminology.hl7.org/CodeSystem/v3-ObservationInterpretation",
        "concept" : [
          {
            "code" : "H",
            "display" : "High"
          },
          {
            "code" : "L",
            "display" : "Low"
          },
          {
            "code" : "I",
            "display" : "Intermediate"
          }
        ]
      }
    ]
  }
}