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Resource Task "PGxRecEx05"
Profile: Followup Recommendation
status: requested
intent: proposal
code: Decrease dose (LOINC#LA26422-8)
description: For amitriptyline, a 50% reduction in starting dose is recommended with therapeutic drug monitoring to guide dose adjustment. Refer to current guidelines for dosage and recommendations at https://cpicpgx.org/guidelines/guideline-for- tricyclic-antidepressants-and-cyp2d6-and-cyp2c19/. If CYP2D6 genotyping is available, refer to the current guidelines for dosing recommendations.
for: Patient/CGPatientExample01 " EVERYMAN"
reasonReference: Observation/TxImp05: Poor metabolizer