Profile Comparison between http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant vs http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant

Left:Variant (http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant)
Right:Variant (http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant)

Messages

ErrorStructureDefinition.versionValues for version differ: '1.0.0' vs '1.1.0'
InformationStructureDefinition.statusValues for status differ: 'draft' vs 'active'
InformationStructureDefinition.dateValues for date differ: '2017-05-20T00:00:00-04:00' vs '2021-04-13T19:13:37+00:00'
InformationStructureDefinition.publisherValues for publisher differ: 'HL7 Clinical Genomics WG' vs 'HL7 International Clinical Genomics Work Group'
InformationStructureDefinition.jurisdictionAdded the item 'http://unstats.un.org/unsd/methods/m49/m49.htm#001'
WarningObservationElements differ in short: 'Variant' 'Measurements and simple assertions'
WarningObservationElements differ in definition: 'Details about a set of changes in the tested sample compared to a reference sequence.' 'Measurements and simple assertions made about a patient, device or other subject.'
WarningObservationElements differ in comments: 'This change can be simple/discrete (relatively short), structural (potentially very large), or complex (consisting of multiple independent co-occurring variations).' 'Used for simple observations such as device measurements, laboratory atomic results, vital signs, height, weight, smoking status, comments, etc. Other resources are used to provide context for observations such as laboratory reports, etc.'
WarningObservation.statusElements differ in comments: '… This should generally be 'completed' or 'revised'.' 'This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid.'
WarningObservation.categoryElements differ in comments: '… This should be populated with 'lab'.' 'In addition to the required category valueset, this element allows various categorization schemes based on the owner’s definition of the category and effectively multiple categories can be used at once. The level of granularity is defined by the category concepts in the value set.'
WarningObservation.codeElements differ in short: 'Genetic variant assessment' 'Type of observation (code / type)'
WarningObservation.codeElements differ in definition: 'Where testing scenarios are intended to assess the prescence or absence of a known set of DNA variants (e.g. tumor profiling using genotyping technology), then the Genetic Variant Assessment is used in conjunction with answer list supports structured communication of these findings. Of note, 'No Call' is different from 'Absent', because 'No Call' did not result in the determination of the marker's presents or absents. This may be due to test failure or specimen specific context which renders the test ineffective.' 'Describes what was observed. Sometimes this is called the observation 'name'.'
WarningObservation.subjectElements differ in comments: '… This must be the same patient as on the DiagnosticReport unless combining data from multiple fetuses or family members in a single report.' 'One would expect this element to be a cardinality of 1..1. The only circumstance in which the subject can be missing is when the observation is made by a device that does not know the patient. In this case, the observation SHALL be matched to a patient through some context/channel matching technique, and at this point, the observation should be updated.'
WarningObservation.value[x]Elements differ in short: 'Present|Absent|No call|Indeterminate' 'Actual result'
WarningObservation.value[x]Elements differ in definition: 'Indicates whether the indicated variation was found or not.' 'The information determined as a result of making the observation, if the information has a simple value.'
WarningObservation.value[x]Elements differ in comments: 'If not searching for specific variations and merely reporting what's found, this element should be set to 'Present'.' 'An observation may have; 1) a single value here, 2) both a value and a set of related or component values, or 3) only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section] below.'
WarningObservation.methodElements differ in short: 'Sequencing | Oligo aCGH | SNP array | BAC aCGH |Curated|+' 'How it was done'
WarningObservation.methodElements differ in definition: 'Indicates the method of variant analysis.' 'Indicates the mechanism used to perform the observation.'
WarningObservation.specimenElements differ in short: 'Specimen examined' 'Specimen used for this observation'
WarningObservation.specimenElements differ in definition: 'The specimen examined to determine genetic information.' 'The specimen that was used when this observation was made.'

Metadata

NameValueComments
.abstractfalse
    .baseDefinitionhttp://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/finding
      .copyrightThis material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.
      • Added the item 'This material contains content from LOINC (http://loinc.org). LOINC is copyright © 1995-2020, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license. LOINC® is a registered United States trademark of Regenstrief Institute, Inc.'
      .date2017-05-20T00:00:00-04:002021-04-13T19:13:37+00:00
      • Values Differ
      .descriptionObservation-related profilesDetails about a set of changes in the tested sample compared to a reference sequence.
      • Values Differ
      .experimentalfalse
      • Removed the item 'false'
      .fhirVersion4.0.1
        .jurisdiction
          ..jurisdiction[0]http://unstats.un.org/unsd/methods/m49/m49.htm#001
          • Added the item 'http://unstats.un.org/unsd/methods/m49/m49.htm#001'
          .kindresource
            .nameVariant
              .publisherHL7 Clinical Genomics WGHL7 International Clinical Genomics Work Group
              • Values Differ
              .purpose
                .statusdraftactive
                • Values Differ
                .titleVariant
                  .typeObservation
                    .urlhttp://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant
                      .version1.0.01.1.0
                      • Values Differ

                      Structure

                      NameL FlagsL Card.L TypeL Description & ConstraintsR FlagsR Card.L TypeL Description & ConstraintsCommentsdoco
                      .. Observation II
                      • Elements differ in short: "Variant" "Measurements and simple assertions"
                      • Elements differ in definition: "Details about a set of changes in the tested sample compared to a reference sequence." "Measurements and simple assertions made about a patient, device or other subject."
                      • Elements differ in comments: "This change can be simple/discrete (relatively short), structural (potentially very large), or complex (consisting of multiple independent co-occurring variations)." "Used for simple observations such as device measurements, laboratory atomic results, vital signs, height, weight, smoking status, comments, etc. Other resources are used to provide context for observations such as laboratory reports, etc."
                      ... id ΣΣ
                        ... meta ΣΣ
                          ... implicitRules ?!Σ?!Σ
                            ... language
                              ... text
                                ... contained
                                  ... extension ExtensionExtension
                                    ... modifierExtension ?!?!
                                      ... identifier ΣΣ
                                        ... basedOn ΣΣ
                                          ... partOf ΣΣ
                                            ... status ?!Σ?!Σ
                                            • Elements differ in comments: "… This should generally be 'completed' or 'revised'." "This element is labeled as a modifier because the status contains codes that mark the resource as not currently valid."
                                            ... category (Slice Definition)
                                            • Elements differ in comments: "… This should be populated with 'lab'." "In addition to the required category valueset, this element allows various categorization schemes based on the owner’s definition of the category and effectively multiple categories can be used at once. The level of granularity is defined by the category concepts in the value set."
                                            ... code ΣΣ
                                            • Elements differ in short: "Genetic variant assessment" "Type of observation (code / type)"
                                            • Elements differ in definition: "Where testing scenarios are intended to assess the prescence or absence of a known set of DNA variants (e.g. tumor profiling using genotyping technology), then the Genetic Variant Assessment is used in conjunction with answer list supports structured communication of these findings. Of note, 'No Call' is different from 'Absent', because 'No Call' did not result in the determination of the marker's presents or absents. This may be due to test failure or specimen specific context which renders the test ineffective." "Describes what was observed. Sometimes this is called the observation "name"."
                                            ... subject ΣΣ
                                            • Elements differ in comments: "… This must be the same patient as on the DiagnosticReport unless combining data from multiple fetuses or family members in a single report." "One would expect this element to be a cardinality of 1..1. The only circumstance in which the subject can be missing is when the observation is made by a device that does not know the patient. In this case, the observation SHALL be matched to a patient through some context/channel matching technique, and at this point, the observation should be updated."
                                            ... focus ΣΣ
                                              ... encounter ΣΣ
                                                ... effective[x] Σ(Slice Definition)Σ
                                                  ... issued ΣΣ
                                                    ... performer ΣΣ
                                                      ... value[x] ΣIΣI(Slice Definition)
                                                      • Elements differ in short: "Present|Absent|No call|Indeterminate" "Actual result"
                                                      • Elements differ in definition: "Indicates whether the indicated variation was found or not." "The information determined as a result of making the observation, if the information has a simple value."
                                                      • Elements differ in comments: "If not searching for specific variations and merely reporting what's found, this element should be set to "Present"." "An observation may have; 1) a single value here, 2) both a value and a set of related or component values, or 3) only a set of related or component values. If a value is present, the datatype for this element should be determined by Observation.code. A CodeableConcept with just a text would be used instead of a string if the field was usually coded, or if the type associated with the Observation.code defines a coded value. For additional guidance, see the [Notes section] below."
                                                      ... dataAbsentReason II
                                                        ... interpretation
                                                          ... note
                                                            ... bodySite
                                                              ... method
                                                              • Elements differ in short: "Sequencing | Oligo aCGH | SNP array | BAC aCGH |Curated|+" "How it was done"
                                                              • Elements differ in definition: "Indicates the method of variant analysis." "Indicates the mechanism used to perform the observation."
                                                              ... specimen
                                                              • Elements differ in short: "Specimen examined" "Specimen used for this observation"
                                                              • Elements differ in definition: "The specimen examined to determine genetic information." "The specimen that was used when this observation was made."
                                                              ... device
                                                                ... referenceRange II
                                                                  .... id
                                                                    .... extension ExtensionExtension
                                                                      .... modifierExtension ?!Σ?!Σ
                                                                        .... low II
                                                                          .... high II
                                                                            .... type
                                                                              .... appliesTo
                                                                                .... age
                                                                                  .... text
                                                                                    ... hasMember ΣΣ
                                                                                      ... derivedFrom ΣΣ
                                                                                        ... component Σ(Slice Definition)Σ(Slice Definition)
                                                                                          .... id
                                                                                            .... extension ExtensionExtension
                                                                                              .... modifierExtension ?!Σ?!Σ
                                                                                                .... code ΣΣ
                                                                                                  .... value[x] ΣΣ
                                                                                                    .... dataAbsentReason II
                                                                                                      .... interpretation
                                                                                                        .... referenceRange

                                                                                                          doco Documentation for this format