This page is part of the Genetic Reporting Implementation Guide (v0.3.0: STU 1 Ballot 2) based on FHIR R4. The current version which supercedes this version is 2.0.0. For a full list of available versions, see the Directory of published versions

Example - Full Bundle HLA genotyping for HLA-A, HLA-B, and HLA-C, using GLStrings

Format(s):

Narrative view

Bundle CG-IG-HLA-FullBundle-01 of type transaction


Entry 1 - Full URL = urn:uuid:13f34265-335c-4853-bc38-0815315edafa

Response:

POST Patient

Resource Patient:

Donor

name: John Storm

gender: male

born: 1986-12-31


Entry 2 - Full URL = urn:uuid:e44fbe33-6084-4ae2-a95e-8bc451c63340

Response:

POST Specimen

Resource Specimen:

a buccal swab

Entry 3 - Full URL = urn:uuid:9243cc20-27bd-4f87-ba90-0328ed474950

Response:

POST Organization

Resource Organization:

aTypingLab, Inc

Entry 4 - Full URL = urn:uuid:00ef18ad-ed04-4b2c-81ee-b69bb243f0d5

Response:

POST Organization

Resource Organization:

aDonorRegistry

Entry 5 - Full URL = urn:uuid:99309303-045e-4cf4-90d7-250d7a7476ea

Response:

POST ServiceRequest

Resource ServiceRequest:

HLA typing request for John Storm

Entry 6 - Full URL = urn:uuid:8200dab6-18a2-4550-b913-a7db480c0804

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-A*01:01:01:01, exon 2"

Entry 7 - Full URL = urn:uuid:7c393185-f15c-45bc-a714-c0fdbea32675

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-A*01:01:01:01, exon 3"

Entry 8 - Full URL = urn:uuid:65c85f14-c3a0-4b72-818f-820e04fcc621

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-A*01:02, exon 2"

Entry 9 - Full URL = urn:uuid:fbba9fe7-0ece-4ec1-9233-a437a8d242a0

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-A*01:02, exon 3"

Entry 10 - Full URL = urn:uuid:b7765bbf-df40-486a-9f2f-404309643de6

Response:

POST Observation

Resource Observation:

HLA-A:01:01:01G

Entry 11 - Full URL = urn:uuid:d98d92a7-0e86-4ae5-b036-b7e1bba6ec32

Response:

POST Observation

Resource Observation:

HLA-A*01:02

Entry 12 - Full URL = urn:uuid:49a86246-4004-42eb-9bdc-f542f93f9228

Response:

POST Observation

Resource Observation:

HLA-A:01:01G+HLA-A*01:02

Entry 13 - Full URL = urn:uuid:cbabf93e-1b4b-46f2-ba1e-d84862670670

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-B*15:01:01:01, exon 2"

Entry 14 - Full URL = urn:uuid:c233ad3d-1572-48d6-93da-0a583535e138

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-B*15:01:01:01, exon 3"

Entry 15 - Full URL = urn:uuid:05fa52d7-5c67-460a-8722-d3460b24d6fe

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-B*57:01:01, exon 2"

Entry 16 - Full URL = urn:uuid:db69e549-6267-4777-b4b9-8813f3329309

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-B*57:01:01, exon 3"

Entry 17 - Full URL = urn:uuid:e2092243-2970-49d2-a90f-b90d1d49715a

Response:

POST Observation

Resource Observation:

HLA-B*15:01:01G

Entry 18 - Full URL = urn:uuid:792be53e-d4fb-4887-a367-815ef6c706e5

Response:

POST Observation

Resource Observation:

HLA-B*57:01:01G

Entry 19 - Full URL = urn:uuid:60613a43-c4cb-4502-b3e2-cf9215feaa70

Response:

POST Observation

Resource Observation:

HLA-B*15:01:01G+HLA-B*57:01:01G

Entry 20 - Full URL = urn:uuid:bb55c2bc-5ad2-4bc1-8ff3-c407d06b12d0

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-C*01:02:01, exon 2"

Entry 21 - Full URL = urn:uuid:46938bb2-0486-4e87-bfd3-89aab2d5e22f

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-C*01:02:01, exon 3"

Entry 22 - Full URL = urn:uuid:2ae2ff34-279e-43c2-9018-b054fd3fc1ce

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-C*03:04:01:01, exon 2"

Entry 23 - Full URL = urn:uuid:19153ef1-68c6-47a2-9676-c4eefbd39af9

Response:

POST MolecularSequence

Resource MolecularSequence:

"HLA-C*03:04:01:01, exon 3"

Entry 24 - Full URL = urn:uuid:709c5315-9403-4867-9d82-0b953836665f

Response:

POST Observation

Resource Observation:

HLA-C*01:02:01G

Entry 25 - Full URL = urn:uuid:8b2aa21c-1426-4717-8ab0-a84d83df7d47

Response:

POST Observation

Resource Observation:

HLA-C*03:04:01G

Entry 26 - Full URL = urn:uuid:0e0a780e-4486-4cd0-bfae-7243c579f208

Response:

POST Observation

Resource Observation:

HLA-C*01:02:01G+HLA-C*03:04:01G

Entry 27 - Full URL = urn:uuid:b0a4b18e-94e7-4b1b-8031-c7ae4bdd8db9

Response:

POST DiagnosticReport

Resource DiagnosticReport:

HLA-A,-B,-C genotyping report for John Storm (MRN:12345)

LOCUS   ALLELE 1            ALLELE 2
HLA-A   HLA-A:01:01G        HLA-A*01:02
HLA-B   HLA-B*15:01:01G     HLA-B*57:01:01G
HLA-C   HLA-C*01:02:01G     HLA-C*03:04:01G

Allele assignments based on IMGT/HLA 3.23
Effective date: 2015-12-15
Method: Sequencing of exons 2 and 3 of HLA Class I genes
Lab: aTypingLab Inc