Evidence Based Medicine on FHIR Implementation Guide
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This page is part of the Evidence Based Medicine on FHIR Implementation Guide (v1.0.0-ballot2: STU1 Ballot 2) based on FHIR (HL7® FHIR® Standard) v6.0.0. No current official version has been published yet. For a full list of available versions, see the Directory of published versions

: ConceptualCohortDefinition: Estimated glomerular filtration rate 45-59 - JSON Representation

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{
  "resourceType" : "Group",
  "id" : "179897",
  "meta" : {
    "versionId" : "9",
    "lastUpdated" : "2025-03-15T20:58:17.869Z",
    "profile" : [
      🔗 "http://hl7.org/fhir/uv/ebm/StructureDefinition/conceptual-cohort-definition"🔗 ,
      "http://hl7.org/fhir/uv/ebm/StructureDefinition/group-r6"
    ]
  },
  "text" : {
    "status" : "empty",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>[No data.]</p></div>"
  },
  "extension" : [
    {
      "url" : "http://hl7.org/fhir/StructureDefinition/artifact-author",
      "valueContactDetail" : {
        "name" : "Brian S. Alper"
      }
    },
    {
      "url" : "http://hl7.org/fhir/uv/ebm/StructureDefinition/cite-as",
      "valueMarkdown" : "ConceptualCohortDefinition: Estimated glomerular filtration rate 45-59 [Database Entry: FHIR Group Resource]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179897. Revised 2025-03-05. Available at: https://fevir.net/resources/Group/179897. Computable resource at: https://fevir.net/resources/Group/179897#json."
    }
  ],
  "url" : "https://fevir.net/resources/Group/179897",
  "identifier" : [
    {
      "type" : {
        "coding" : [
          {
            "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
            "code" : "ACSN",
            "display" : "Accession ID"
          }
        ],
        "text" : "FEvIR Object Identifier"
      },
      "system" : "urn:ietf:rfc:3986",
      "value" : "https://fevir.net/FOI/179897",
      "assigner" : {
        "display" : "Computable Publishing LLC"
      }
    }
  ],
  "name" : "EGFR_45_59",
  "title" : "ConceptualCohortDefinition: Estimated glomerular filtration rate 45-59",
  "status" : "active",
  "publisher" : "Computable Publishing LLC",
  "contact" : [
    {
      "telecom" : [
        {
          "system" : "email",
          "value" : "support@computablepublishing.com"
        }
      ]
    }
  ],
  "description" : "A characteristic of estimated glomerular filtration rate (eGFR) of 45-59 mL/min/1.73m2 is shown here. LOINC Code guidance states 'If transitioning to the new 2021 calculations, note there are separate equations for male and female patients that need to be implemented. The same LOINC code is applied regardless of which sex-based equation is used to generate the result. Laboratories need to build each male and female equation within their LIS and validate per their accreditation requirements.' and 'While LOINC does not have a specific code for reporting the exact equation used to calculate eGFR, it may be appropriate for labs to transmit this information as part of the information contained in the result comment field. The individual laboratory should determine whether it is better to include the equation, or the author(s) of the equation, to identify the method used to perform the eGFR calculation.' This example uses Group.characteristic.determinedByExpression to show where the exact equation may be reported.",
  "copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "membership" : "conceptual",
  "characteristic" : [
    {
      "code" : {
        "coding" : [
          {
            "system" : "http://loinc.org",
            "code" : "98979-8",
            "display" : "Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI 2021)/1.73 sq M"
          }
        ]
      },
      "valueRange" : {
        "low" : {
          "value" : 45
        },
        "high" : {
          "value" : 59,
          "unit" : "milliliter per minute per 1.73 square meter",
          "system" : "http://unitsofmeasure.org",
          "code" : "mL/min/1.73.m2"
        }
      },
      "exclude" : false,
      "description" : "eGFR 45-59 mL/min/1.73m2 with CKD-EPI 2021 formula for a female",
      "determinedByExpression" : {
        "description" : "formula for female adults (in pseudo-code expression)",
        "expression" : "GFR = 141 * min(Scr/κ,1)^α * max(Scr/κ, 1)^-1.209 * 0.993^Age * 1.018",
        "reference" : "https://reference.medscape.com/calculator/251/egfr-using-ckd-epi-2021-update"
      }
    }
  ]
}