Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot2 - STU 1 ballot International flag

This page is part of the Evidence Based Medicine on FHIR Implementation Guide (v1.0.0-ballot2: STU1 Ballot 2) based on FHIR (HL7® FHIR® Standard) v6.0.0. No current official version has been published yet. For a full list of available versions, see the Directory of published versions

Example Evidence: MAGIC-derived Evidence: Body weight with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

Generated Narrative: Evidence 236567

version: 65; Last updated: 2025-03-20 18:40:09+0000

Profile: ComparativeEvidence

RelatesTo

  • type: part-of
  • targetReference: MAGICapp Conversion Report: SGLT2 inhibitors and GLP-1 RA for type 2 diabetes (Identifier: FEvIR Linking Identifier/MAGIC-5288-j1Wqrn-conversion-report)

url: https://fevir.net/resources/Evidence/236567

identifier: FEvIR Object Identifier/https://fevir.net/FOI/236567, outcomeId/109570, picoId/85789, sectionId/73212

name: Body_weight_from_MAGICapp_109570

title: MAGIC-derived Evidence: Body weight with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk

status: Active

publisher: Computable Publishing LLC

contact: support@computablepublishing.com

author: Computable Publishing®: MAGIC-to-FEvIR Converter:

UseContexts

-CodeValue[x]
*Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence CommunicationComparativeEvidence

copyright:

https://creativecommons.org/licenses/by-nc-sa/4.0/

description:

This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.

assertion:

GLP-1 receptor agonists may reduce body weight compared with standard care.

variableDefinition

description:

Adults with type 2 diabetes with moderate CV risk

variableRole: Population

observed: Adults with type 2 diabetes and established CVD (but no CKD)

variableDefinition

description:

GroupAssignment: GLP-1 RA vs. Standard care

variableRole: Exposure

comparatorCategory: Standard care

observed: GroupAssignment: GLP-1 RA vs. Standard care

variableDefinition

description:

Body weight

variableRole: Outcome

observed: Body weight

synthesisType: SYSTEMATIC_REVIEW

studyDesign: NOTSET

statistic

description:

MD -1.45 Kg (CI95 -1.72 Kg to -1.18 Kg)

statisticType: Mean Difference

quantity: -1.45 Kg

SampleSizes

-NumberOfStudiesNumberOfParticipants
*6044432

AttributeEstimates

-TypeRange
*CI95-1.72--1.18 Kg

certainty

description:

Due to very serious inconsistency

type: Overall certainty

rating: Low certainty

Subcomponents

-TypeRating
*Risk of BiasNOTSET
*InconsistencyVERY_SERIOUS
*IndirectnessNOTSET
*ImprecisionNOTSET
*Publication BiasNOTSET