This page is part of the Evidence Based Medicine on FHIR Implementation Guide (v1.0.0-ballot2: STU1 Ballot 2) based on FHIR (HL7® FHIR® Standard) v6.0.0. No current official version has been published yet. For a full list of available versions, see the Directory of published versions
Generated Narrative: Evidence 236567
version: 65; Last updated: 2025-03-20 18:40:09+0000
Profile: ComparativeEvidence
RelatesTo
- type: part-of
- targetReference: MAGICapp Conversion Report: SGLT2 inhibitors and GLP-1 RA for type 2 diabetes (Identifier: FEvIR Linking Identifier/MAGIC-5288-j1Wqrn-conversion-report)
url: https://fevir.net/resources/Evidence/236567
identifier: FEvIR Object Identifier/https://fevir.net/FOI/236567, outcomeId/109570, picoId/85789, sectionId/73212
name: Body_weight_from_MAGICapp_109570
title: MAGIC-derived Evidence: Body weight with GLP-1 RA vs. Standard care in Adults with type 2 diabetes with moderate CV risk
status: Active
publisher: Computable Publishing LLC
contact: support@computablepublishing.com
author: Computable Publishing®: MAGIC-to-FEvIR Converter:
Code | Value[x] |
Evidence Based Medicine on FHIR Implementation Guide Code System evidence-communication: Evidence Communication | ComparativeEvidence |
copyright:
https://creativecommons.org/licenses/by-nc-sa/4.0/
description:
This Evidence Resource is referenced in an example for the EBMonFHIR Implementation Guide.
assertion:
GLP-1 receptor agonists may reduce body weight compared with standard care.
variableDefinition
description:
Adults with type 2 diabetes with moderate CV risk
variableRole: Population
observed: Adults with type 2 diabetes and established CVD (but no CKD)
variableDefinition
description:
GroupAssignment: GLP-1 RA vs. Standard care
variableRole: Exposure
comparatorCategory: Standard care
variableDefinition
description:
Body weight
variableRole: Outcome
observed: Body weight
synthesisType: SYSTEMATIC_REVIEW
studyDesign: NOTSET
statistic
description:
MD -1.45 Kg (CI95 -1.72 Kg to -1.18 Kg)
statisticType: Mean Difference
quantity: -1.45 Kg
SampleSizes
NumberOfStudies NumberOfParticipants 60 44432 AttributeEstimates
Type Range CI95 -1.72--1.18 Kg
certainty
description:
Due to very serious inconsistency
type: Overall certainty
rating: Low certainty
Subcomponents
Type Rating Risk of Bias NOTSET Inconsistency VERY_SERIOUS Indirectness NOTSET Imprecision NOTSET Publication Bias NOTSET