Evidence Based Medicine on FHIR Implementation Guide
1.0.0-ballot - ballot International flag

This page is part of the Evidence Based Medicine on FHIR Implementation Guide (v1.0.0-ballot: STU1 Ballot 1) based on FHIR (HL7® FHIR® Standard) v5.0.0. . For a full list of available versions, see the Directory of published versions

: EGFR_45_59 - XML Representation

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<Group xmlns="http://hl7.org/fhir">
  <id value="179897"/>
  <meta>
    <versionId value="6"/>
    <lastUpdated value="2023-12-04T14:58:17.731Z"/>
    <profile
             value="http://hl7.org/fhir/uv/ebm/StructureDefinition/cohort-definition"/>
    <profile value="http://hl7.org/fhir/uv/ebm/StructureDefinition/group-r6"/>
  </meta>
  <text>
    <status value="extensions"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Group</b><a name="179897"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Group &quot;179897&quot; Version &quot;6&quot; Updated &quot;2023-12-04 14:58:17+0000&quot; </p><p style="margin-bottom: 0px">Profiles: <a href="StructureDefinition-cohort-definition.html">CohortDefinition</a>, <a href="StructureDefinition-group-r6.html">GroupR6</a></p></div><p><b>Artifact related artifact</b>: </p><p><b>Artifact Title</b>: CohortDefinition: Estimated glomerular filtration rate 45-59</p><p><b>Artifact URL</b>: <a href="https://fevir.net/resources/Group/179897">https://fevir.net/resources/Group/179897</a></p><p><b>Artifact Publisher</b>: Computable Publishing LLC</p><p><b>Artifact Copyright</b>: https://creativecommons.org/licenses/by-nc-sa/4.0/</p><p><b>Artifact Contact</b>: <a href="mailto:support@computablepublishing.com">support@computablepublishing.com</a></p><p><b>Artifact Author</b>: Brian S. Alper: </p><blockquote><p><b>modifierExtension[http://hl7.org/fhir/StructureDefinition/artifact-status]</b></p></blockquote><p><b>identifier</b>: FEvIR Object Identifier: 179897</p><p><b>type</b>: animal</p><p><b>membership</b>: definitional</p><p><b>name</b>: EGFR_45_59</p><p><b>description</b>: A characteristic of estimated glomerular filtration rate (eGFR) of 45-59 mL/min/1.73m2 is shown here. LOINC Code guidance states 'If transitioning to the new 2021 calculations, note there are separate equations for male and female patients that need to be implemented. The same LOINC code is applied regardless of which sex-based equation is used to generate the result. Laboratories need to build each male and female equation within their LIS and validate per their accreditation requirements.' and 'While LOINC does not have a specific code for reporting the exact equation used to calculate eGFR, it may be appropriate for labs to transmit this information as part of the information contained in the result comment field. The individual laboratory should determine whether it is better to include the equation, or the author(s) of the equation, to identify the method used to perform the eGFR calculation.' This example uses Group.characteristic.determinedByExpression to show where the exact equation may be reported.</p><h3>Characteristics</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Extension</b></td><td><b>Code</b></td><td><b>Value[x]</b></td><td><b>Exclude</b></td></tr><tr><td style="display: none">*</td><td>, </td><td>Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI 2021) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#98979-8)</span></td><td>45-59</td><td>false</td></tr></table></div>
  </text>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/artifact-relatedArtifact">
    <valueRelatedArtifact>
      <type value="cite-as"/>
      <citation
                value="CohortDefinition: Estimated glomerular filtration rate 45-59  [Group]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179897. Revised 2023-12-03. Available at: https://fevir.net/resources/Group/179897. Computable resource at: https://fevir.net/resources/Group/179897."/>
    </valueRelatedArtifact>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/artifact-title">
    <valueString
                 value="CohortDefinition: Estimated glomerular filtration rate 45-59"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/artifact-url">
    <valueUri value="https://fevir.net/resources/Group/179897"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/artifact-publisher">
    <valueString value="Computable Publishing LLC"/>
  </extension>
  <extension
             url="http://hl7.org/fhir/StructureDefinition/artifact-copyright">
    <valueMarkdown
                   value="https://creativecommons.org/licenses/by-nc-sa/4.0/"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/artifact-contact">
    <valueContactDetail>
      <telecom>
        <system value="email"/>
        <value value="support@computablepublishing.com"/>
      </telecom>
    </valueContactDetail>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/artifact-author">
    <valueContactDetail>
      <name value="Brian S. Alper"/>
    </valueContactDetail>
  </extension>
  <modifierExtension
                     url="http://hl7.org/fhir/StructureDefinition/artifact-status">
    <valueCode value="active"/>
  </modifierExtension>
  <identifier>
    <type>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/v2-0203"/>
        <code value="ACSN"/>
        <display value="Accession ID"/>
      </coding>
      <text value="FEvIR Object Identifier"/>
    </type>
    <system value="https://fevir.net"/>
    <value value="179897"/>
    <assigner>
      <display value="Computable Publishing LLC"/>
    </assigner>
  </identifier>
  <type value="animal"/>
  <membership value="definitional"/>
  <name value="EGFR_45_59"/>
  <description
               value="A characteristic of estimated glomerular filtration rate (eGFR) of 45-59 mL/min/1.73m2 is shown here. LOINC Code guidance states 'If transitioning to the new 2021 calculations, note there are separate equations for male and female patients that need to be implemented. The same LOINC code is applied regardless of which sex-based equation is used to generate the result. Laboratories need to build each male and female equation within their LIS and validate per their accreditation requirements.' and 'While LOINC does not have a specific code for reporting the exact equation used to calculate eGFR, it may be appropriate for labs to transmit this information as part of the information contained in the result comment field. The individual laboratory should determine whether it is better to include the equation, or the author(s) of the equation, to identify the method used to perform the eGFR calculation.' This example uses Group.characteristic.determinedByExpression to show where the exact equation may be reported."/>
  <characteristic>
    <extension
               url="http://hl7.org/fhir/uv/ebm/StructureDefinition/characteristic-description">
      <valueMarkdown
                     value="eGFR 45-59 mL/min/1.73m2 with CKD-EPI 2021 formula for a female"/>
    </extension>
    <extension
               url="http://hl7.org/fhir/uv/ebm/StructureDefinition/characteristic-determined-by-expression">
      <valueExpression>
        <description
                     value="formula for female adults (in pseudo-code expression)"/>
        <expression
                    value="GFR = 141 * min(Scr/κ,1)^α * max(Scr/κ, 1)^-1.209 * 0.993^Age * 1.018"/>
        <reference
                   value="https://reference.medscape.com/calculator/251/egfr-using-ckd-epi-2021-update"/>
      </valueExpression>
    </extension>
    <code>
      <coding>
        <system value="http://loinc.org"/>
        <code value="98979-8"/>
        <display
                 value="Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI 2021)"/>
      </coding>
    </code>
    <valueRange>
      <low>
        <value value="45"/>
      </low>
      <high>
        <value value="59"/>
        <unit value="milliliter per minute per 1.73 square meter"/>
        <system value="http://unitsofmeasure.org"/>
        <code value="mL/min/1.73.m2"/>
      </high>
    </valueRange>
    <exclude value="false"/>
  </characteristic>
</Group>