Profile Comparison between http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient vs http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient

Messages

Metadata

Name	Value		Comments
abstract	false
baseDefinition	http://hl7.org/fhir/StructureDefinition/SubstanceDefinition
copyright
date	2024-04-08T17:51:06+00:00	2024-12-11T13:47:08+00:00	Values Differ
description	Provides sufficient information to identify an inactive substance and raw materials and its source when stability data is required in the submission.
experimental
fhirVersion	5.0.0
jurisdiction
jurisdiction[0]	urn:iso:std:iso:3166#US
kind	resource
name	ExcipientRaw
publisher	HL7 International / Biomedical Research and Regulation
purpose
status	active
title	Excipient Drug Substance
type	SubstanceDefinition
url	http://hl7.org/fhir/us/pq-cmc-fda/StructureDefinition/pqcmc-excipient
version	1.0.0-ballot	1.0.0	Values Differ

Structure

Name	L Flags	L Card.	L Type	L Description & Constraints	R Flags	R Card.	R Type	R Description & Constraints	Comments
SubstanceDefinition	C	0..*	SubstanceDefinition	The detailed description of a substance, typically at a level beyond what is used for prescribing cmc-when-unii-required: A UNII is required in code for any of these categories: 'Chemical', 'Mixture', 'Nucleic Acids','Polymer','Protein'. cmc-name-isbt: Name.type ISBT 128 required for blood products. cmc-source-material: IF raw material source type equals Microbial, Animal, Plant, Insect or Human THEN the 4 source related attributes are required and the manufacturer and supplier information is highly desirable.	C	0..*	SubstanceDefinition	The detailed description of a substance, typically at a level beyond what is used for prescribing cmc-when-unii-required: A UNII is required in code for any of these categories: 'Chemical', 'Mixture', 'Nucleic Acids','Polymer'. A UniProt code is required for any of these categories: 'Protein' cmc-name-isbt: Name.type ISBT 128 required for blood products. cmc-source-material: IF raw material source type equals Microbial, Animal, Plant, Insect or Human THEN the 4 source related attributes are required and the manufacturer and supplier information is highly desirable.
id	Σ	0..1	id	Logical id of this artifact	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource	Σ	0..1	Meta	Metadata about the resource
id		0..1	id	Unique id for inter-element referencing					Removed this element
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url					Removed this element
versionId	Σ	0..1	id	Version specific identifier					Removed this element
lastUpdated	Σ	0..1	instant	When the resource version last changed					Removed this element
source	Σ	0..1	uri	Identifies where the resource comes from					Removed this element
profile	SΣ	1..1	canonical(StructureDefinition)	Profiles this resource claims to conform to					Removed this element
security	Σ	0..*	Coding	Security Labels applied to this resource Binding: ?? (extensible): Security Labels from the Healthcare Privacy and Security Classification System.					Removed this element
tag	Σ	0..*	Coding	Tags applied to this resource Binding: ?? (example): Codes that represent various types of tags, commonly workflow-related; e.g. "Needs review by Dr. Jones".					Removed this element
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: ?? (required): IETF language tag for a human language Additional Bindings Purpose ?? Starter Set		0..1	code	Language of the resource content Binding: ?? (required): IETF language tag for a human language Additional Bindings Purpose ?? Starter Set
text		0..1	Narrative	Text summary of the resource, for human interpretation		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored	?!Σ	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..1	Identifier	optional user designated identifier	Σ	0..1	Identifier	optional user designated identifier
version	Σ	0..1	string	A business level version identifier of the substance	Σ	0..1	string	A business level version identifier of the substance
status	Σ	0..1	CodeableConcept	Status of substance within the catalogue e.g. active, retired Binding: ?? (preferred): The lifecycle status of an artifact.	Σ	0..1	CodeableConcept	Status of substance within the catalogue e.g. active, retired Binding: ?? (preferred): The lifecycle status of an artifact.
classification	SΣ	1..*	CodeableConcept	Substance Type Binding: ?? (required)	SΣ	1..1	CodeableConcept	Substance Type Binding: ?? (required)	Element maximum cardinalities differ: '2147483647' vs '1'
domain	Σ	0..1	CodeableConcept	If the substance applies to human or veterinary use Binding: ?? (example): Applicable domain for this product (e.g. human, veterinary).	Σ	0..1	CodeableConcept	If the substance applies to human or veterinary use Binding: ?? (example): Applicable domain for this product (e.g. human, veterinary).
grade	Σ	1..1	CodeableConcept	Quality Standard Binding: ?? (example): The quality standard, established benchmark, to which a substance complies	Σ	1..*	CodeableConcept	Quality Standard Binding: ?? (required)	Element maximum cardinalities differ: '1' vs '2147483647'
id		0..1	id	Unique id for inter-element referencing					Removed this element
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url					Removed this element
coding	Σ	0..*	Coding	Code defined by a terminology system Binding: ?? (required)					Removed this element
text	Σ	0..1	string	Plain text representation of the concept					Removed this element
description	Σ	0..1	markdown	Textual description of the substance	Σ	0..1	markdown	Textual description of the substance
informationSource	Σ	0..*	Reference(Citation)	Supporting literature	Σ	0..*	Reference(Citation)	Supporting literature
note	Σ	0..*	Annotation	Textual comment about the substance's catalogue or registry record	Σ	0..*	Annotation	Textual comment about the substance's catalogue or registry record
manufacturer	SΣ	0..1	Reference(Manufacturing and/or Test Site Organization)	The entity that creates, makes, produces or fabricates the substance	SΣ	0..*	LiteralReference(Basic Organization) {b}	The entity that creates, makes, produces or fabricates the substance	Element maximum cardinalities differ: '1' vs '2147483647'
supplier	SΣ	0..1	Reference(Supplier Organization)	An entity that is the source for the substance. It may be different from the manufacturer	SΣ	0..1	LiteralReference(Basic Organization) {b}	An entity that is the source for the substance. It may be different from the manufacturer
moiety	Σ	0..*	BackboneElement	Moiety, for structural modifications	Σ	0..*	BackboneElement	Moiety, for structural modifications
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
role	Σ	0..1	CodeableConcept	Role that the moiety is playing	Σ	0..1	CodeableConcept	Role that the moiety is playing
identifier	Σ	0..1	Identifier	Identifier by which this moiety substance is known	Σ	0..1	Identifier	Identifier by which this moiety substance is known
name	Σ	0..1	string	Textual name for this moiety substance	Σ	0..1	string	Textual name for this moiety substance
stereochemistry	Σ	0..1	CodeableConcept	Stereochemistry type Binding: ?? (example): The optical rotation type of a substance.	Σ	0..1	CodeableConcept	Stereochemistry type Binding: ?? (example): The optical rotation type of a substance.
opticalActivity	Σ	0..1	CodeableConcept	Optical activity type Binding: ?? (example): The optical rotation type of a substance.	Σ	0..1	CodeableConcept	Optical activity type Binding: ?? (example): The optical rotation type of a substance.
molecularFormula	Σ	0..1	string	Molecular formula for this moiety (e.g. with the Hill system)	Σ	0..1	string	Molecular formula for this moiety (e.g. with the Hill system)
amount[x]	Σ	0..1	Quantity, string	Quantitative value for this moiety	Σ	0..1	Quantity, string	Quantitative value for this moiety
measurementType	Σ	0..1	CodeableConcept	The measurement type of the quantitative value Binding: ?? (example): The relationship between two substance types.	Σ	0..1	CodeableConcept	The measurement type of the quantitative value Binding: ?? (example): The relationship between two substance types.
characterization	Σ	0..*	BackboneElement	General specifications for this substance	Σ	0..*	BackboneElement	General specifications for this substance
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
technique	Σ	0..1	CodeableConcept	The method used to find the characterization e.g. HPLC Binding: ?? (example): The method used to elucidate the characterization of the drug substance.	Σ	0..1	CodeableConcept	The method used to find the characterization e.g. HPLC Binding: ?? (example): The method used to elucidate the characterization of the drug substance.
form	Σ	0..1	CodeableConcept	Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt form Binding: ?? (example)	Σ	0..1	CodeableConcept	Describes the nature of the chemical entity and explains, for instance, whether this is a base or a salt form Binding: ?? (example)
description	Σ	0..1	markdown	The description or justification in support of the interpretation of the data file	Σ	0..1	markdown	The description or justification in support of the interpretation of the data file
file	Σ	0..*	Attachment	The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysis	Σ	0..*	Attachment	The data produced by the analytical instrument or a pictorial representation of that data. Examples: a JCAMP, JDX, or ADX file, or a chromatogram or spectrum analysis
property	Σ	0..*	BackboneElement	General specifications for this substance	Σ	0..*	BackboneElement	General specifications for this substance
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
type	Σ	1..1	CodeableConcept	A code expressing the type of property Binding: ?? (example): This value set includes all observable entity codes from SNOMED CT - provided as an exemplar value set.	Σ	1..1	CodeableConcept	A code expressing the type of property Binding: ?? (example): This value set includes all observable entity codes from SNOMED CT - provided as an exemplar value set.
value[x]	Σ	0..1	CodeableConcept, Quantity, date, boolean, Attachment	A value for the property	Σ	0..1	CodeableConcept, Quantity, date, boolean, Attachment	A value for the property
referenceInformation	Σ	0..1	Reference(SubstanceReferenceInformation)	General information detailing this substance	Σ	0..1	Reference(SubstanceReferenceInformation)	General information detailing this substance
molecularWeight	Σ	0..*	BackboneElement	The average mass of a molecule of a compound	Σ	0..*	BackboneElement	The average mass of a molecule of a compound
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
method	Σ	0..1	CodeableConcept	The method by which the weight was determined Binding: ?? (example): The method by which the substance weight was measured.	Σ	0..1	CodeableConcept	The method by which the weight was determined Binding: ?? (example): The method by which the substance weight was measured.
type	Σ	0..1	CodeableConcept	Type of molecular weight e.g. exact, average, weight average Binding: ?? (example): The type of substance weight measurement.	Σ	0..1	CodeableConcept	Type of molecular weight e.g. exact, average, weight average Binding: ?? (example): The type of substance weight measurement.
amount	Σ	1..1	Quantity	Used to capture quantitative values for a variety of elements	Σ	1..1	Quantity	Used to capture quantitative values for a variety of elements
structure	Σ	0..1	BackboneElement	Structural information	Σ	0..1	BackboneElement	Structural information
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
stereochemistry	Σ	0..1	CodeableConcept	Stereochemistry type Binding: ?? (example): The optical rotation type of a substance.	Σ	0..1	CodeableConcept	Stereochemistry type Binding: ?? (example): The optical rotation type of a substance.
opticalActivity	Σ	0..1	CodeableConcept	Optical activity type Binding: ?? (example): The optical rotation type of a substance.	Σ	0..1	CodeableConcept	Optical activity type Binding: ?? (example): The optical rotation type of a substance.
molecularFormula	Σ	0..1	string	An expression which states the number and type of atoms present in a molecule of a substance	Σ	0..1	string	An expression which states the number and type of atoms present in a molecule of a substance
molecularFormulaByMoiety	Σ	0..1	string	Specified per moiety according to the Hill system	Σ	0..1	string	Specified per moiety according to the Hill system
molecularWeight	Σ	0..1	See molecularWeight (SubstanceDefinition)	The molecular weight or weight range	Σ	0..1	See molecularWeight (SubstanceDefinition)	The molecular weight or weight range
technique	Σ	0..*	CodeableConcept	The method used to find the structure e.g. X-ray, NMR Binding: ?? (example): The method used to elucidate the structure of the drug substance.	Σ	0..*	CodeableConcept	The method used to find the structure e.g. X-ray, NMR Binding: ?? (example): The method used to elucidate the structure of the drug substance.
sourceDocument	Σ	0..*	Reference(DocumentReference)	Source of information for the structure	Σ	0..*	Reference(DocumentReference)	Source of information for the structure
representation	Σ	0..*	BackboneElement	A depiction of the structure of the substance	Σ	0..*	BackboneElement	A depiction of the structure of the substance
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
type	Σ	0..1	CodeableConcept	The kind of structural representation (e.g. full, partial) Binding: ?? (example): A format of a substance representation.	Σ	0..1	CodeableConcept	The kind of structural representation (e.g. full, partial) Binding: ?? (example): A format of a substance representation.
representation	Σ	0..1	string	The structural representation as a text string in a standard format	Σ	0..1	string	The structural representation as a text string in a standard format
format	Σ	0..1	CodeableConcept	The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format) Binding: ?? (example): A format of a substance representation.	Σ	0..1	CodeableConcept	The format of the representation e.g. InChI, SMILES, MOLFILE (note: not the physical file format) Binding: ?? (example): A format of a substance representation.
document	Σ	0..1	Reference(DocumentReference)	An attachment with the structural representation e.g. a structure graphic or AnIML file	Σ	0..1	Reference(DocumentReference)	An attachment with the structural representation e.g. a structure graphic or AnIML file
code	SΣ	1..*	BackboneElement	Codes associated with the substance	SΣ	1..*	BackboneElement	Codes associated with the substance Slice: Unordered, Open by value:code.coding.system
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
code	SΣ	1..1	CodeableConcept	The specific code	Σ	0..1	CodeableConcept	The specific code	Elements differ in definition for mustSupport: 'true' vs 'false' Element minimum cardinalities differ: '1' vs '0'
id		0..1	id	Unique id for inter-element referencing					Removed this element
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url					Removed this element
Slices for coding	Σ	0..*	Coding	Code defined by a terminology system Slice: Unordered, Open by value:system					Removed this element
text	Σ	0..1	string	Plain text representation of the concept					Removed this element
status	Σ	0..1	CodeableConcept	Status of the code assignment, for example 'provisional', 'approved' Binding: ?? (preferred): The lifecycle status of an artifact.	Σ	0..1	CodeableConcept	Status of the code assignment, for example 'provisional', 'approved' Binding: ?? (preferred): The lifecycle status of an artifact.
statusDate	Σ	0..1	dateTime	The date at which the code status was changed	Σ	0..1	dateTime	The date at which the code status was changed
note	Σ	0..*	Annotation	Any comment can be provided in this field	Σ	0..*	Annotation	Any comment can be provided in this field
source	Σ	0..*	Reference(DocumentReference)	Supporting literature	Σ	0..*	Reference(DocumentReference)	Supporting literature
Slices for name	SΣC	1..*	BackboneElement	Substance Name Slice: Unordered, Closed by value:type.coding cmc-name-preferred: Name.preferred: at most one = true	SΣC	1..*	BackboneElement	Substance Name Slice: Unordered, Closed by value:type cmc-name-preferred: Name.preferred: at most one = true
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
name	Σ	1..1	string	The actual name	Σ	1..1	string	The actual name
type	Σ	0..1	CodeableConcept	Name type e.g. 'systematic', 'scientific, 'brand' Binding: ?? (example): The type of a name given to a substance.	Σ	0..1	CodeableConcept	Name type e.g. 'systematic', 'scientific, 'brand' Binding: ?? (required)
status	Σ	0..1	CodeableConcept	The status of the name e.g. 'current', 'proposed' Binding: ?? (preferred): The lifecycle status of an artifact.	Σ	0..1	CodeableConcept	The status of the name e.g. 'current', 'proposed' Binding: ?? (preferred): The lifecycle status of an artifact.
preferred	SΣ	0..1	boolean	True when the name type is Substance Name	SΣ	0..1	boolean	True when the name type is Substance Name
language	Σ	0..*	CodeableConcept	Human language that the name is written in Binding: ?? (required): IETF language tag for a human language Additional Bindings Purpose ?? Starter Set	Σ	0..*	CodeableConcept	Human language that the name is written in Binding: ?? (required): IETF language tag for a human language Additional Bindings Purpose ?? Starter Set
domain	Σ	0..*	CodeableConcept	The use context of this name e.g. as an active ingredient or as a food colour additive Binding: ?? (example): The use context of a substance name for example if there is a different name when used as a drug active ingredient as opposed to a food colour additive.	Σ	0..*	CodeableConcept	The use context of this name e.g. as an active ingredient or as a food colour additive Binding: ?? (example): The use context of a substance name for example if there is a different name when used as a drug active ingredient as opposed to a food colour additive.
jurisdiction	Σ	0..*	CodeableConcept	The jurisdiction where this name applies Binding: ?? (example): Jurisdiction codes	Σ	0..*	CodeableConcept	The jurisdiction where this name applies Binding: ?? (example): Jurisdiction codes
synonym	Σ	0..*	See name (SubstanceDefinition)	A synonym of this particular name, by which the substance is also known	Σ	0..*	See name (SubstanceDefinition)	A synonym of this particular name, by which the substance is also known
translation	Σ	0..*	See name (SubstanceDefinition)	A translation for this name into another human language	Σ	0..*	See name (SubstanceDefinition)	A translation for this name into another human language
official	Σ	0..*	BackboneElement	Details of the official nature of this name	Σ	0..*	BackboneElement	Details of the official nature of this name
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
authority	Σ	0..1	CodeableConcept	Which authority uses this official name Binding: ?? (preferred): An authority that officates substance names.	Σ	0..1	CodeableConcept	Which authority uses this official name Binding: ?? (preferred): An authority that officates substance names.
status	Σ	0..1	CodeableConcept	The status of the official name, for example 'draft', 'active' Binding: ?? (preferred): The lifecycle status of an artifact.	Σ	0..1	CodeableConcept	The status of the official name, for example 'draft', 'active' Binding: ?? (preferred): The lifecycle status of an artifact.
date	Σ	0..1	dateTime	Date of official name change	Σ	0..1	dateTime	Date of official name change
source	Σ	0..*	Reference(DocumentReference)	Supporting literature	Σ	0..*	Reference(DocumentReference)	Supporting literature
relationship	Σ	0..*	BackboneElement	A link between this substance and another	Σ	0..*	BackboneElement	A link between this substance and another
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
substanceDefinition[x]	Σ	0..1	Reference(SubstanceDefinition), CodeableConcept	A pointer to another substance, as a resource or a representational code	Σ	0..1	Reference(SubstanceDefinition), CodeableConcept	A pointer to another substance, as a resource or a representational code
type	Σ	1..1	CodeableConcept	For example "salt to parent", "active moiety" Binding: ?? (example): The relationship between two substance types.	Σ	1..1	CodeableConcept	For example "salt to parent", "active moiety" Binding: ?? (example): The relationship between two substance types.
isDefining	Σ	0..1	boolean	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationships	Σ	0..1	boolean	For example where an enzyme strongly bonds with a particular substance, this is a defining relationship for that enzyme, out of several possible relationships
amount[x]	Σ	0..1	Quantity, Ratio, string	A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some other	Σ	0..1	Quantity, Ratio, string	A numeric factor for the relationship, e.g. that a substance salt has some percentage of active substance in relation to some other
ratioHighLimitAmount	Σ	0..1	Ratio	For use when the numeric has an uncertain range	Σ	0..1	Ratio	For use when the numeric has an uncertain range
comparator	Σ	0..1	CodeableConcept	An operator for the amount, for example "average", "approximately", "less than" Binding: ?? (example): The relationship between two substance types.	Σ	0..1	CodeableConcept	An operator for the amount, for example "average", "approximately", "less than" Binding: ?? (example): The relationship between two substance types.
source	Σ	0..*	Reference(DocumentReference)	Supporting literature	Σ	0..*	Reference(DocumentReference)	Supporting literature
nucleicAcid	Σ	0..1	Reference(SubstanceNucleicAcid)	Data items specific to nucleic acids	Σ	0..1	Reference(SubstanceNucleicAcid)	Data items specific to nucleic acids
polymer	Σ	0..1	Reference(SubstancePolymer)	Data items specific to polymers	Σ	0..1	Reference(SubstancePolymer)	Data items specific to polymers
protein	Σ	0..1	Reference(SubstanceProtein)	Data items specific to proteins	Σ	0..1	Reference(SubstanceProtein)	Data items specific to proteins
sourceMaterial	SΣ	1..1	BackboneElement	Material or taxonomic/anatomical source	SΣ	1..1	BackboneElement	Material or taxonomic/anatomical source
id		0..1	string	Unique id for inter-element referencing		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations		0..*	Extension	Additional content defined by implementations
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
type	Σ	1..1	CodeableConcept	Source Type Binding: ?? (example): A classification that provides the origin of the substance raw material.	Σ	1..1	CodeableConcept	Source Type Binding: ?? (required)
id		0..1	id	Unique id for inter-element referencing					Removed this element
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url					Removed this element
coding	Σ	0..*	Coding	Code defined by a terminology system Binding: ?? (required)					Removed this element
text	Σ	0..1	string	Plain text representation of the concept					Removed this element
genus	SΣ	0..1	CodeableConcept	The genus of an organism e.g. the Latin epithet of the plant/animal scientific name Binding: ?? (example): The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.	S	0..1	??	Source Organism Genus Binding: ?? (example): The genus of an organism, typically referring to the Latin epithet of the genus element of the plant/animal scientific name.
id		0..1	id	Unique id for inter-element referencing					Removed this element
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url					Removed this element
coding	Σ	0..0							Removed this element
text	Σ	1..1	string	Source Organism					Removed this element
species	SΣ	0..1	CodeableConcept	Source Organism Binding: ?? (example): A species of origin a substance raw material.	S	0..1	??	Source Organism Species Binding: ?? (example): A species of origin a substance raw material.
id		0..1	id	Unique id for inter-element referencing					Removed this element
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url					Removed this element
coding	Σ	0..0							Removed this element
text	Σ	1..1	string	Plain text representation of the concept					Removed this element
part	SΣ	0..1	CodeableConcept	Source Organism Part Binding: ?? (example): An anatomical origin of the source material within an organism.	S	0..1	??	Source Organism Part Binding: ?? (example): An anatomical origin of the source material within an organism.
id		0..1	id	Unique id for inter-element referencing					Removed this element
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url					Removed this element
coding	Σ	0..0							Removed this element
text	Σ	1..1	string	Plain text representation of the concept					Removed this element
countryOfOrigin	SΣC	0..1	CodeableConcept	Source Organism Country of Origin Binding: ?? (required): Jurisdiction codes cmc-iso-genc-overlap: Only country codes that are also member of GENC can be used.	SΣ	0..1	CodeableConcept	Source Organism Country of Origin Binding: ?? (required)
id		0..1	id	Unique id for inter-element referencing					Removed this element
Slices for extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url					Removed this element
coding	SΣ	1..1	Coding	Code defined by a terminology system					Removed this element
text	Σ	0..1	string	Plain text representation of the concept					Removed this element
Documentation for this format