HL7 FHIR Implementation Guide: Profiles for ICSR Transfusion and Vaccination Adverse Event Detection and Reporting
1.0.0 - STU 1

This page is part of the Profiles for ICSR Transfusion and Vaccination Adverse Event Detection and Reporting (v1.0.0: STU 1) based on FHIR R4. This is the current published version. For a full list of available versions, see the Directory of published versions

: VAERS Bundle for Connectathon Sample - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Bundle;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "ConnectathonVAERSBundle"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-bundle";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-bundle>     ]
  ];
  fhir:Bundle.identifier [
     fhir:Identifier.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.3.22" ];
     fhir:Identifier.value [ fhir:value "BATCH20210105142444-0500533f2636-a404-13c5-10e3-7d293893227a" ]
  ];
  fhir:Bundle.type [ fhir:value "message"];
  fhir:Bundle.timestamp [ fhir:value "2021-01-05T14:24:44-05:00"^^xsd:dateTime];
  fhir:Bundle.entry [
     fhir:index 0;
     fhir:Bundle.entry.fullUrl [ fhir:value "MessageHeader/US-IBM-e380bc14-2a03-7b64-c3f5-22daea2aa495" ];
     fhir:Bundle.entry.resource <MessageHeader/US-IBM-e380bc14-2a03-7b64-c3f5-22daea2aa495>
  ], [
     fhir:index 1;
     fhir:Bundle.entry.fullUrl [ fhir:value "Composition/VAERSExample" ];
     fhir:Bundle.entry.resource <Composition/VAERSExample>
  ], [
     fhir:index 2;
     fhir:Bundle.entry.fullUrl [ fhir:value "Organization/VAERSSender" ];
     fhir:Bundle.entry.resource <Organization/VAERSSender>
  ], [
     fhir:index 3;
     fhir:Bundle.entry.fullUrl [ fhir:value "PractitionerRole/VAERSAuthorRole" ];
     fhir:Bundle.entry.resource <PractitionerRole/VAERSAuthorRole>
  ], [
     fhir:index 4;
     fhir:Bundle.entry.fullUrl [ fhir:value "Practitioner/VAERSAuthor" ];
     fhir:Bundle.entry.resource <Practitioner/VAERSAuthor>
  ], [
     fhir:index 5;
     fhir:Bundle.entry.fullUrl [ fhir:value "Patient/VAERSPatient" ];
     fhir:Bundle.entry.resource <Patient/VAERSPatient>
  ], [
     fhir:index 6;
     fhir:Bundle.entry.fullUrl [ fhir:value "AdverseEvent/VAERSExampleEvent" ];
     fhir:Bundle.entry.resource <AdverseEvent/VAERSExampleEvent>
  ], [
     fhir:index 7;
     fhir:Bundle.entry.fullUrl [ fhir:value "Immunization/VAERSExampleImmunization" ];
     fhir:Bundle.entry.resource <Immunization/VAERSExampleImmunization>
  ], [
     fhir:index 8;
     fhir:Bundle.entry.fullUrl [ fhir:value "MedicationAdministration/VAERSHydrocortisoneAdministration" ];
     fhir:Bundle.entry.resource <MedicationAdministration/VAERSHydrocortisoneAdministration>
  ].

<MessageHeader/US-IBM-e380bc14-2a03-7b64-c3f5-22daea2aa495> a fhir:MessageHeader;
  fhir:Resource.id [ fhir:value "US-IBM-e380bc14-2a03-7b64-c3f5-22daea2aa495"];
  fhir:Resource.meta [
     fhir:Meta.lastUpdated [ fhir:value "2021-01-05T14:24:44+05:00"^^xsd:dateTime ];
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageheader";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageheader>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"US-IBM-e380bc14-2a03-7b64-c3f5-22daea2aa495\" Updated \"2021-01-05T09:24:44Z\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-messageheader.html\">ICSR MessageHeader</a></p></div><p><b>Message Processing Category</b>: notification</p><p><b>event</b>: Patient Adverse Event (Details: http://terminology.hl7.org/CodeSystem/v3-ActCode code PAT_ADV_EVNT = 'patient adverse event', stated as 'Patient Adverse Event')</p><h3>Destinations</h3><table class=\"grid\"><tr><td>-</td><td><b>Endpoint</b></td></tr><tr><td>*</td><td><a href=\"http://example.org/CBERVAERS\">http://example.org/CBERVAERS</a></td></tr></table><p><b>sender</b>: <a href=\"#Organization_VAERSSender\">See above (Organization/VAERSSender)</a></p><h3>Sources</h3><table class=\"grid\"><tr><td>-</td><td><b>Endpoint</b></td></tr><tr><td>*</td><td><a href=\"http://example.org/BEST-Pilot\">http://example.org/BEST-Pilot</a></td></tr></table><p><b>reason</b>: Indicates receipt of a public health report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/us/medmorph/2021Jan/CodeSystem-us-ph-triggerdefinition-namedevents.html\">US Public Health TriggerDefinition Named Events</a>#received-public-health-report)</span></p><p><b>focus</b>: <a href=\"#Composition_VAERSExample\">See above (Composition/VAERSExample)</a></p></div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/medmorph/StructureDefinition/ext-messageProcessingCategory" ];
     fhir:Extension.valueCode [ fhir:value "notification" ]
  ];
  fhir:MessageHeader.eventCoding [
     fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-ActCode" ];
     fhir:Coding.code [ fhir:value "PAT_ADV_EVNT" ];
     fhir:Coding.display [ fhir:value "Patient Adverse Event" ]
  ];
  fhir:MessageHeader.destination [
     fhir:index 0;
     fhir:MessageHeader.destination.endpoint [ fhir:value "http://example.org/CBERVAERS" ]
  ];
  fhir:MessageHeader.sender [
     fhir:Reference.reference [ fhir:value "Organization/VAERSSender" ]
  ];
  fhir:MessageHeader.source [
     fhir:MessageHeader.source.endpoint [ fhir:value "http://example.org/BEST-Pilot" ]
  ];
  fhir:MessageHeader.reason [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/medmorph/CodeSystem/us-ph-triggerdefinition-namedevents" ];
       fhir:Coding.code [ fhir:value "received-public-health-report" ]     ]
  ];
  fhir:MessageHeader.focus [
     fhir:index 0;
     fhir:Reference.reference [ fhir:value "Composition/VAERSExample" ]
  ].

<Composition/VAERSExample> a fhir:Composition;
  fhir:Resource.id [ fhir:value "VAERSExample"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-composition";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-composition>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"VAERSExample\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-composition.html\">ICSR Composition</a></p></div><blockquote><p><b>AdditionalDocumentInformation</b></p><p><b>value</b>: false</p></blockquote><blockquote><p><b>ExpeditedReport</b></p><p><b>value</b>: false</p><p><b>value</b>: Non-Expedited AE <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#2)</span></p></blockquote><p><b>FirstSenderType</b>: Regulator <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#1)</span></p><p><b>CombinationProductReport</b>: false</p><p><b>FirstReceiveDate</b>: 2021-01-05</p><p><b>MostRecentDate</b>: 2021-01-05</p><p><b>CaseIdentifier</b>: id: US-IBM-e380bc14-2a03-7b64-c3f5-22daea2aa495</p><p><b>identifier</b>: id: US-IBM-e380bc14-2a03-7b64-c3f5-22daea2aa495</p><p><b>status</b>: final</p><p><b>type</b>: Adverse event note <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#85893-6)</span></p><p><b>category</b>: Spontaneous report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#1)</span></p><p><b>date</b>: 2021-01-05T14:24:44+05:00</p><p><b>author</b>: <a href=\"#PractitionerRole_VAERSAuthorRole\">See above (PractitionerRole/VAERSAuthorRole)</a></p><p><b>title</b>: ICSR Submission</p></div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "availableFlag" ];
       fhir:Extension.valueBoolean [ fhir:value "false"^^xsd:boolean ]     ];
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-additionaldocumentinformation" ]
  ], [
     fhir:index 1;
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "localCriteriaFlag" ];
       fhir:Extension.valueBoolean [ fhir:value "false"^^xsd:boolean ]     ], [
       fhir:index 1;
       fhir:Extension.url [ fhir:value "localCriteriaReportType" ];
       fhir:Extension.valueCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.1003" ];
           fhir:Coding.code [ fhir:value "2" ];
           fhir:Coding.display [ fhir:value "Non-Expedited AE" ]         ]       ]     ];
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-expeditedreport" ]
  ], [
     fhir:index 2;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-firstsendertype" ];
     fhir:Extension.valueCodeableConcept [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.3" ];
         fhir:Coding.code [ fhir:value "1" ];
         fhir:Coding.display [ fhir:value "Regulator" ]       ]     ]
  ], [
     fhir:index 3;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-combinationproductreport" ];
     fhir:Extension.valueBoolean [ fhir:value "false"^^xsd:boolean ]
  ], [
     fhir:index 4;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-firstreceivedate" ];
     fhir:Extension.valueDateTime [ fhir:value "2021-01-05"^^xsd:date ]
  ], [
     fhir:index 5;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-mostrecentdate" ];
     fhir:Extension.valueDateTime [ fhir:value "2021-01-05"^^xsd:date ]
  ], [
     fhir:index 6;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-caseidentifier" ];
     fhir:Extension.valueIdentifier [
       fhir:Identifier.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.3.2" ];
       fhir:Identifier.value [ fhir:value "US-IBM-e380bc14-2a03-7b64-c3f5-22daea2aa495" ]     ]
  ];
  fhir:Composition.identifier [
     fhir:Identifier.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.3.1" ];
     fhir:Identifier.value [ fhir:value "US-IBM-e380bc14-2a03-7b64-c3f5-22daea2aa495" ]
  ];
  fhir:Composition.status [ fhir:value "final"];
  fhir:Composition.type [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       a loinc:85893-6;
       fhir:Coding.system [ fhir:value "http://loinc.org" ];
       fhir:Coding.code [ fhir:value "85893-6" ];
       fhir:Coding.display [ fhir:value "Adverse event note" ]     ]
  ];
  fhir:Composition.category [
     fhir:index 0;
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.2" ];
       fhir:Coding.code [ fhir:value "1" ];
       fhir:Coding.display [ fhir:value "Spontaneous report" ]     ]
  ];
  fhir:Composition.subject [
     fhir:Reference.reference [ fhir:value "Patient/VAERSPatient" ]
  ];
  fhir:Composition.date [ fhir:value "2021-01-05T14:24:44+05:00"^^xsd:dateTime];
  fhir:Composition.author [
     fhir:index 0;
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-authorprimarysource" ];
       fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]     ];
     fhir:Reference.reference [ fhir:value "PractitionerRole/VAERSAuthorRole" ]
  ];
  fhir:Composition.title [ fhir:value "ICSR Submission"];
  fhir:Composition.section [
     fhir:index 0;
     fhir:Composition.section.title [ fhir:value "Reaction/Event" ];
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS" ];
         fhir:Coding.code [ fhir:value "ReactionEvent" ]       ]     ];
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ];
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Developed acute facial nerve paralysis after ED administration of influenza vaccine</div>"     ];
     fhir:Composition.section.entry [
       fhir:index 0;
       fhir:Reference.reference [ fhir:value "AdverseEvent/VAERSExampleEvent" ]     ]
  ], [
     fhir:index 1;
     fhir:Composition.section.title [ fhir:value "Drug Information" ];
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS" ];
         fhir:Coding.code [ fhir:value "DrugInformation" ]       ]     ];
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ];
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">ED administration of influenza vaccine</div>"     ];
     fhir:Composition.section.entry [
       fhir:index 0;
       fhir:Reference.reference [ fhir:value "Immunization/VAERSExampleImmunization" ]     ], [
       fhir:index 1;
       fhir:Reference.reference [ fhir:value "MedicationAdministration/VAERSHydrocortisoneAdministration" ]     ]
  ], [
     fhir:index 2;
     fhir:Composition.section.title [ fhir:value "Case Summary Narrative" ];
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS" ];
         fhir:Coding.code [ fhir:value "CaseSummaryNarrative" ]       ]     ];
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ];
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Header: FDA CBER BEST Automated AE Reporting Prototype Case BEST Detection Phenotype Algorithm: sharepoint link BEST Certainty: Definite BEST Severity: Non-Severe BEST Causality: Probable Onset location for reaction: Preliminary investigation results: Developed acute facial nerve paralysis after ED administration of influenza vaccine; Reaction Type: vax_bells_palsy; Illness at Time of Vaccination: 1. illness, Problem, Chronic systolic (congestive) heart failure, Date 20170430; Notes: 1. notes, Progress Note - Nurse, Patient Care Documentation, Progress Note : Patient suffered face weakness from unknown cause. Patient had idiopathic facial nerve palsy and showed rapid progression. Palsy improved lot facial paralysis identified., Date 20170423;</div>"     ]
  ], [
     fhir:index 3;
     fhir:Composition.section.title [ fhir:value "Relevant Medical History" ];
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS" ];
         fhir:Coding.code [ fhir:value "RelevantMedicalHistory" ]       ]     ];
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ];
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Long term (current) use of anticoagulants</div>"     ]
  ].

<Organization/VAERSSender> a fhir:Organization;
  fhir:Resource.id [ fhir:value "VAERSSender"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageorganization";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageorganization>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"VAERSSender\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-messageorganization.html\">MessageHeader Organization</a></p></div><p><b>DepartmentName</b>: sender department</p><p><b>active</b>: true</p><p><b>type</b>: Pharmaceutical Company <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#1)</span></p><p><b>name</b>: sender organization</p><p><b>telecom</b>: <a href=\"tel:+0112345678\">+01 123 456 78</a>, fax: +01 123 456 89, <a href=\"mailto:email@city.us\">email@city.us</a></p><p><b>address</b>: street city CA postcode US </p><h3>Contacts</h3><table class=\"grid\"><tr><td>-</td><td><b>Name</b></td></tr><tr><td>*</td><td>sender gname sender fname </td></tr></table></div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-departmentname" ];
     fhir:Extension.valueString [ fhir:value "sender department" ]
  ];
  fhir:Organization.active [ fhir:value "true"^^xsd:boolean];
  fhir:Organization.type [
     fhir:index 0;
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.7" ];
       fhir:Coding.code [ fhir:value "1" ];
       fhir:Coding.display [ fhir:value "Pharmaceutical Company" ]     ]
  ];
  fhir:Organization.name [ fhir:value "sender organization"];
  fhir:Organization.telecom [
     fhir:index 0;
     fhir:ContactPoint.system [ fhir:value "phone" ];
     fhir:ContactPoint.value [ fhir:value "+01 123 456 78" ]
  ], [
     fhir:index 1;
     fhir:ContactPoint.system [ fhir:value "fax" ];
     fhir:ContactPoint.value [ fhir:value "+01 123 456 89" ]
  ], [
     fhir:index 2;
     fhir:ContactPoint.system [ fhir:value "email" ];
     fhir:ContactPoint.value [ fhir:value "email@city.us" ]
  ];
  fhir:Organization.address [
     fhir:index 0;
     fhir:Address.line [
       fhir:value "street";
       fhir:index 0     ];
     fhir:Address.city [ fhir:value "city" ];
     fhir:Address.state [ fhir:value "CA" ];
     fhir:Address.postalCode [ fhir:value "postcode" ];
     fhir:Address.country [ fhir:value "US" ]
  ];
  fhir:Organization.contact [
     fhir:index 0;
     fhir:Organization.contact.name [
       fhir:HumanName.family [ fhir:value "sender fname" ];
       fhir:HumanName.given [
         fhir:value "sender gname";
         fhir:index 0       ];
       fhir:HumanName.prefix [
         fhir:value "sender title";
         fhir:index 0       ]     ]
  ].

<PractitionerRole/VAERSAuthorRole> a fhir:PractitionerRole;
  fhir:Resource.id [ fhir:value "VAERSAuthorRole"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitionerrole";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitionerrole>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"VAERSAuthorRole\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-authorpractitionerrole.html\">PractitionerRole Author</a></p></div><p><b>practitioner</b>: <a href=\"#Practitioner_VAERSAuthor\">See above (Practitioner/VAERSAuthor)</a></p><p><b>organization</b>: <a href=\"#Organization_VAERSSender\">See above (Organization/VAERSSender)</a></p><p><b>code</b>: Physician <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#1)</span></p><p><b>telecom</b>: <a href=\"mailto:admin@admin.com\">admin@admin.com</a>, ph: 3333333333</p></div>"
  ];
  fhir:PractitionerRole.practitioner [
     fhir:Reference.reference [ fhir:value "Practitioner/VAERSAuthor" ]
  ];
  fhir:PractitionerRole.organization [
     fhir:Reference.reference [ fhir:value "Organization/VAERSSender" ]
  ];
  fhir:PractitionerRole.code [
     fhir:index 0;
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.6" ];
       fhir:Coding.code [ fhir:value "1" ];
       fhir:Coding.display [ fhir:value "Physician" ]     ]
  ];
  fhir:PractitionerRole.telecom [
     fhir:index 0;
     fhir:ContactPoint.system [ fhir:value "email" ];
     fhir:ContactPoint.value [ fhir:value "admin@admin.com" ]
  ], [
     fhir:index 1;
     fhir:ContactPoint.system [ fhir:value "phone" ];
     fhir:ContactPoint.value [ fhir:value "3333333333" ]
  ].

<Practitioner/VAERSAuthor> a fhir:Practitioner;
  fhir:Resource.id [ fhir:value "VAERSAuthor"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitioner";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitioner>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"VAERSAuthor\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-authorpractitioner.html\">Practitioner Author</a></p></div><p><b>identifier</b>: id: NI</p><p><b>name</b>: asdhj Admin </p><p><b>address</b>: US </p></div>"
  ];
  fhir:Practitioner.identifier [
     fhir:index 0;
     fhir:Identifier.system [ fhir:value "http://hl7.org/fhir/sid/us-npi" ];
     fhir:Identifier.value [ fhir:value "NI" ]
  ];
  fhir:Practitioner.name [
     fhir:index 0;
     fhir:HumanName.family [ fhir:value "Admin" ];
     fhir:HumanName.given [
       fhir:value "asdhj";
       fhir:index 0     ]
  ];
  fhir:Practitioner.address [
     fhir:index 0;
     fhir:Address.country [ fhir:value "US" ]
  ].

<Patient/VAERSPatient> a fhir:Patient;
  fhir:Resource.id [ fhir:value "VAERSPatient"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-patient";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-patient>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"VAERSPatient\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-patient.html\">ICSR Patient</a></p></div><p><b>identifier</b>: id: 123456789</p><p><b>name</b>: FNAME LNAME </p><p><b>gender</b>: male</p><p><b>birthDate</b>: 1955-07-22</p></div>"
  ];
  fhir:Patient.identifier [
     fhir:index 0;
     fhir:Identifier.system [ fhir:value "http://hl7.org/fhir/sid/us-ssn" ];
     fhir:Identifier.value [ fhir:value "123456789" ]
  ];
  fhir:Patient.name [
     fhir:index 0;
     fhir:HumanName.family [ fhir:value "LNAME" ];
     fhir:HumanName.given [
       fhir:value "FNAME";
       fhir:index 0     ]
  ];
  fhir:Patient.gender [ fhir:value "male"];
  fhir:Patient.birthDate [ fhir:value "1955-07-22"^^xsd:date].

<AdverseEvent/VAERSExampleEvent> a fhir:AdverseEvent;
  fhir:Resource.id [ fhir:value "VAERSExampleEvent"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/vaers-adverseevent";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/vaers-adverseevent>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"VAERSExampleEvent\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-vaers-adverseevent.html\">VAERS Adverse Event</a></p></div><p><b>actuality</b>: actual</p><p><b>event</b>: Bell's Palsy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (meddra.org#10004223)</span></p><p><b>subject</b>: <a href=\"#Patient_VAERSPatient\">See above (Patient/VAERSPatient)</a></p><p><b>date</b>: 2017-04-23</p><p><b>seriousness</b>: Serious <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.0.0/CodeSystem-adverse-event-seriousness.html\">AdverseEventSeriousness</a>#serious)</span></p><p><b>outcome</b>: Recovering <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R4/codesystem-adverse-event-outcome.html\">AdverseEventOutcome</a>#recovering)</span></p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#Immunization_VAERSExampleImmunization\">See above (Immunization/VAERSExampleImmunization)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td>-</td><td><b>ProductRelatedness</b></td></tr><tr><td>*</td><td>Suspect</td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_VAERSHydrocortisoneAdministration\">See above (MedicationAdministration/VAERSHydrocortisoneAdministration)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td>-</td><td><b>ProductRelatedness</b></td></tr><tr><td>*</td><td>Concomitant</td></tr></table></blockquote></div>"
  ];
  fhir:AdverseEvent.actuality [ fhir:value "actual"];
  fhir:AdverseEvent.event [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://meddra.org" ];
       fhir:Coding.code [ fhir:value "10004223" ];
       fhir:Coding.display [ fhir:value "Bell's Palsy" ]     ]
  ];
  fhir:AdverseEvent.subject [
     fhir:Reference.reference [ fhir:value "Patient/VAERSPatient" ]
  ];
  fhir:AdverseEvent.date [ fhir:value "2017-04-23"^^xsd:date];
  fhir:AdverseEvent.seriousness [
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-eventseriousness" ];
       fhir:Extension.valueCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.19" ];
           fhir:Coding.code [ fhir:value "26" ]         ]       ]     ];
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/adverse-event-seriousness" ];
       fhir:Coding.code [ fhir:value "serious" ]     ]
  ];
  fhir:AdverseEvent.outcome [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/adverse-event-outcome" ];
       fhir:Coding.code [ fhir:value "recovering" ]     ]
  ];
  fhir:AdverseEvent.suspectEntity [
     fhir:index 0;
     fhir:AdverseEvent.suspectEntity.instance [
       fhir:Reference.reference [ fhir:value "Immunization/VAERSExampleImmunization" ]     ];
     fhir:AdverseEvent.suspectEntity.causality [
       fhir:index 0;
       fhir:AdverseEvent.suspectEntity.causality.productRelatedness [ fhir:value "Suspect" ]     ]
  ], [
     fhir:index 1;
     fhir:AdverseEvent.suspectEntity.instance [
       fhir:Reference.reference [ fhir:value "MedicationAdministration/VAERSHydrocortisoneAdministration" ]     ];
     fhir:AdverseEvent.suspectEntity.causality [
       fhir:index 0;
       fhir:AdverseEvent.suspectEntity.causality.productRelatedness [ fhir:value "Concomitant" ]     ]
  ].

<Immunization/VAERSExampleImmunization> a fhir:Immunization;
  fhir:Resource.id [ fhir:value "VAERSExampleImmunization"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-immunization";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-immunization>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"VAERSExampleImmunization\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-immunization.html\">ICSR Immunization</a></p></div><p><b>AgeAtVaccination</b>: 12 years<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code y = 'y')</span></p><p><b>status</b>: completed</p><p><b>vaccineCode</b>: 7046101903 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.0.0/CodeSystem-v3-ndc.html\">National drug codes</a>#7046101903)</span></p><p><b>patient</b>: <a href=\"#Patient_VAERSPatient\">See above (Patient/VAERSPatient)</a></p><p><b>occurrence</b>: 2017-04-23</p><p><b>primarySource</b>: false</p></div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-ageatvaccination" ];
     fhir:Extension.valueAge [
       fhir:Quantity.value [ fhir:value "12"^^xsd:decimal ];
       fhir:Quantity.unit [ fhir:value "years" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "y" ]     ]
  ];
  fhir:Immunization.status [ fhir:value "completed"];
  fhir:Immunization.vaccineCode [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://hl7.org/fhir/sid/ndc" ];
       fhir:Coding.code [ fhir:value "7046101903" ]     ]
  ];
  fhir:Immunization.patient [
     fhir:Reference.reference [ fhir:value "Patient/VAERSPatient" ]
  ];
  fhir:Immunization.occurrenceDateTime [ fhir:value "2017-04-23"^^xsd:date];
  fhir:Immunization.primarySource [ fhir:value "false"^^xsd:boolean].

<MedicationAdministration/VAERSHydrocortisoneAdministration> a fhir:MedicationAdministration;
  fhir:Resource.id [ fhir:value "VAERSHydrocortisoneAdministration"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-medicationadministration";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-medicationadministration>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"VAERSHydrocortisoneAdministration\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-medicationadministration.html\">ICSR MedicationAdministration</a></p></div><p><b>status</b>: completed</p><p><b>medication</b>: hydrocortisone 10 MG Oral Tablet <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.0.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#197782)</span></p><p><b>subject</b>: <a href=\"#Patient_VAERSPatient\">See above (Patient/VAERSPatient)</a></p><p><b>effective</b>: 2017-04-23</p></div>"
  ];
  fhir:MedicationAdministration.status [ fhir:value "completed"];
  fhir:MedicationAdministration.medicationCodeableConcept [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ];
       fhir:Coding.code [ fhir:value "197782" ]     ]
  ];
  fhir:MedicationAdministration.subject [
     fhir:Reference.reference [ fhir:value "Patient/VAERSPatient" ]
  ];
  fhir:MedicationAdministration.effectiveDateTime [ fhir:value "2017-04-23"^^xsd:date].

# - ontology header ------------------------------------------------------------

 a owl:Ontology;
  owl:imports fhir:fhir.ttl.