HL7 FHIR Implementation Guide: Profiles for ICSR Transfusion and Vaccination Adverse Event Detection and Reporting
1.0.0 - STU 1

This page is part of the Profiles for ICSR Transfusion and Vaccination Adverse Event Detection and Reporting (v1.0.0: STU 1) based on FHIR R4. This is the current published version. For a full list of available versions, see the Directory of published versions

: FAERS Bundle for Connectathon Sample - TTL Representation

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@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <http://loinc.org/rdf#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

 a fhir:Bundle;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "ConnectathonFAERSBundle"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-bundle";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-bundle>     ]
  ];
  fhir:Bundle.type [ fhir:value "message"];
  fhir:Bundle.entry [
     fhir:index 0;
     fhir:Bundle.entry.fullUrl [ fhir:value "MessageHeader/beafb541-3eab-eb9e-1bf1-5fa477d56e77" ];
     fhir:Bundle.entry.resource <MessageHeader/beafb541-3eab-eb9e-1bf1-5fa477d56e77>
  ], [
     fhir:index 1;
     fhir:Bundle.entry.fullUrl [ fhir:value "Composition/FAERSExample" ];
     fhir:Bundle.entry.resource <Composition/FAERSExample>
  ], [
     fhir:index 2;
     fhir:Bundle.entry.fullUrl [ fhir:value "Organization/FDA" ];
     fhir:Bundle.entry.resource <Organization/FDA>
  ], [
     fhir:index 3;
     fhir:Bundle.entry.fullUrl [ fhir:value "Organization/BESTPrototype" ];
     fhir:Bundle.entry.resource <Organization/BESTPrototype>
  ], [
     fhir:index 4;
     fhir:Bundle.entry.fullUrl [ fhir:value "PractitionerRole/BESTAuthorRole" ];
     fhir:Bundle.entry.resource <PractitionerRole/BESTAuthorRole>
  ], [
     fhir:index 5;
     fhir:Bundle.entry.fullUrl [ fhir:value "Practitioner/BESTAuthor" ];
     fhir:Bundle.entry.resource <Practitioner/BESTAuthor>
  ], [
     fhir:index 6;
     fhir:Bundle.entry.fullUrl [ fhir:value "Patient/BESTPatient" ];
     fhir:Bundle.entry.resource <Patient/BESTPatient>
  ], [
     fhir:index 7;
     fhir:Bundle.entry.fullUrl [ fhir:value "Observation/BESTPatientAgeGroup" ];
     fhir:Bundle.entry.resource <Observation/BESTPatientAgeGroup>
  ], [
     fhir:index 8;
     fhir:Bundle.entry.fullUrl [ fhir:value "AdverseEvent/FAERSExampleEvent" ];
     fhir:Bundle.entry.resource <AdverseEvent/FAERSExampleEvent>
  ], [
     fhir:index 9;
     fhir:Bundle.entry.fullUrl [ fhir:value "Procedure/FAERSExampleTransfusion" ];
     fhir:Bundle.entry.resource <Procedure/FAERSExampleTransfusion>
  ], [
     fhir:index 10;
     fhir:Bundle.entry.fullUrl [ fhir:value "BiologicallyDerivedProduct/FAERSBloodProduct" ];
     fhir:Bundle.entry.resource <BiologicallyDerivedProduct/FAERSBloodProduct>
  ], [
     fhir:index 11;
     fhir:Bundle.entry.fullUrl [ fhir:value "MedicationAdministration/FAERSEpinephrine" ];
     fhir:Bundle.entry.resource <MedicationAdministration/FAERSEpinephrine>
  ], [
     fhir:index 12;
     fhir:Bundle.entry.fullUrl [ fhir:value "MedicationAdministration/FAERSDiphenhydramine" ];
     fhir:Bundle.entry.resource <MedicationAdministration/FAERSDiphenhydramine>
  ].

<MessageHeader/beafb541-3eab-eb9e-1bf1-5fa477d56e77> a fhir:MessageHeader;
  fhir:Resource.id [ fhir:value "beafb541-3eab-eb9e-1bf1-5fa477d56e77"];
  fhir:Resource.meta [
     fhir:Meta.lastUpdated [ fhir:value "2021-01-05T14:14:39+06:00"^^xsd:dateTime ];
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageheader";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageheader>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"beafb541-3eab-eb9e-1bf1-5fa477d56e77\" Updated \"2021-01-05T08:14:39Z\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-messageheader.html\">ICSR MessageHeader</a></p></div><p><b>Message Processing Category</b>: notification</p><p><b>event</b>: Patient Adverse Event (Details: http://terminology.hl7.org/CodeSystem/v3-ActCode code PAT_ADV_EVNT = 'patient adverse event', stated as 'Patient Adverse Event')</p><h3>Destinations</h3><table class=\"grid\"><tr><td>-</td><td><b>Endpoint</b></td><td><b>Receiver</b></td></tr><tr><td>*</td><td><a href=\"http://example.org/ZZFDA\">http://example.org/ZZFDA</a></td><td><a href=\"#Organization_FDA\">See above (Organization/FDA)</a></td></tr></table><p><b>sender</b>: <a href=\"#Organization_BESTPrototype\">See above (Organization/BESTPrototype)</a></p><h3>Sources</h3><table class=\"grid\"><tr><td>-</td><td><b>Endpoint</b></td></tr><tr><td>*</td><td><a href=\"http://example.org/BEST-Pilot\">http://example.org/BEST-Pilot</a></td></tr></table><p><b>reason</b>: Indicates receipt of a public health report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/us/medmorph/2021Jan/CodeSystem-us-ph-triggerdefinition-namedevents.html\">US Public Health TriggerDefinition Named Events</a>#received-public-health-report)</span></p><p><b>focus</b>: <a href=\"#Composition_FAERSExample\">See above (Composition/FAERSExample)</a></p></div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/medmorph/StructureDefinition/ext-messageProcessingCategory" ];
     fhir:Extension.valueCode [ fhir:value "notification" ]
  ];
  fhir:MessageHeader.eventCoding [
     fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-ActCode" ];
     fhir:Coding.code [ fhir:value "PAT_ADV_EVNT" ];
     fhir:Coding.display [ fhir:value "Patient Adverse Event" ]
  ];
  fhir:MessageHeader.destination [
     fhir:index 0;
     fhir:MessageHeader.destination.endpoint [ fhir:value "http://example.org/ZZFDA" ];
     fhir:MessageHeader.destination.receiver [
       fhir:Reference.reference [ fhir:value "Organization/FDA" ]     ]
  ];
  fhir:MessageHeader.sender [
     fhir:Reference.reference [ fhir:value "Organization/BESTPrototype" ]
  ];
  fhir:MessageHeader.source [
     fhir:MessageHeader.source.endpoint [ fhir:value "http://example.org/BEST-Pilot" ]
  ];
  fhir:MessageHeader.reason [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/medmorph/CodeSystem/us-ph-triggerdefinition-namedevents" ];
       fhir:Coding.code [ fhir:value "received-public-health-report" ]     ]
  ];
  fhir:MessageHeader.focus [
     fhir:index 0;
     fhir:Reference.reference [ fhir:value "Composition/FAERSExample" ]
  ].

<Composition/FAERSExample> a fhir:Composition;
  fhir:Resource.id [ fhir:value "FAERSExample"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-composition";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-composition>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"FAERSExample\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-composition.html\">ICSR Composition</a></p></div><blockquote><p><b>AdditionalDocumentInformation</b></p><p><b>value</b>: false</p></blockquote><blockquote><p><b>ExpeditedReport</b></p><p><b>value</b>: false</p><p><b>value</b>: Non-Expedited AE <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#2)</span></p></blockquote><p><b>FirstSenderType</b>: Other <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#2)</span></p><p><b>CombinationProductReport</b>: false</p><p><b>FirstReceiveDate</b>: 2021-01-05</p><p><b>MostRecentDate</b>: 2021-01-05</p><p><b>CaseIdentifier</b>: id: BEST_beafb541-3eab-eb9e-1bf1-5fa477d56e77</p><p><b>identifier</b>: id: BEST_beafb541-3eab-eb9e-1bf1-5fa477d56e77</p><p><b>status</b>: final</p><p><b>type</b>: Adverse event note <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#85893-6)</span></p><p><b>category</b>: Spontaneous report <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#1)</span></p><p><b>date</b>: 2021-01-05</p><p><b>author</b>: <a href=\"#PractitionerRole_BESTAuthorRole\">See above (PractitionerRole/BESTAuthorRole)</a></p><p><b>title</b>: ICSR Submission</p></div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "availableFlag" ];
       fhir:Extension.valueBoolean [ fhir:value "false"^^xsd:boolean ]     ];
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-additionaldocumentinformation" ]
  ], [
     fhir:index 1;
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "localCriteriaFlag" ];
       fhir:Extension.valueBoolean [ fhir:value "false"^^xsd:boolean ]     ], [
       fhir:index 1;
       fhir:Extension.url [ fhir:value "localCriteriaReportType" ];
       fhir:Extension.valueCodeableConcept [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.1003" ];
           fhir:Coding.code [ fhir:value "2" ];
           fhir:Coding.display [ fhir:value "Non-Expedited AE" ]         ]       ]     ];
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-expeditedreport" ]
  ], [
     fhir:index 2;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-firstsendertype" ];
     fhir:Extension.valueCodeableConcept [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.3" ];
         fhir:Coding.code [ fhir:value "2" ];
         fhir:Coding.display [ fhir:value "Other" ]       ]     ]
  ], [
     fhir:index 3;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-combinationproductreport" ];
     fhir:Extension.valueBoolean [ fhir:value "false"^^xsd:boolean ]
  ], [
     fhir:index 4;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-firstreceivedate" ];
     fhir:Extension.valueDateTime [ fhir:value "2021-01-05"^^xsd:date ]
  ], [
     fhir:index 5;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-mostrecentdate" ];
     fhir:Extension.valueDateTime [ fhir:value "2021-01-05"^^xsd:date ]
  ], [
     fhir:index 6;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-caseidentifier" ];
     fhir:Extension.valueIdentifier [
       fhir:Identifier.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.3.2" ];
       fhir:Identifier.value [ fhir:value "BEST_beafb541-3eab-eb9e-1bf1-5fa477d56e77" ]     ]
  ];
  fhir:Composition.identifier [
     fhir:Identifier.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.3.1" ];
     fhir:Identifier.value [ fhir:value "BEST_beafb541-3eab-eb9e-1bf1-5fa477d56e77" ]
  ];
  fhir:Composition.status [ fhir:value "final"];
  fhir:Composition.type [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       a loinc:85893-6;
       fhir:Coding.system [ fhir:value "http://loinc.org" ];
       fhir:Coding.code [ fhir:value "85893-6" ];
       fhir:Coding.display [ fhir:value "Adverse event note" ]     ]
  ];
  fhir:Composition.category [
     fhir:index 0;
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.2" ];
       fhir:Coding.code [ fhir:value "1" ];
       fhir:Coding.display [ fhir:value "Spontaneous report" ]     ]
  ];
  fhir:Composition.subject [
     fhir:Reference.reference [ fhir:value "Patient/BESTPatient" ]
  ];
  fhir:Composition.date [ fhir:value "2021-01-05"^^xsd:date];
  fhir:Composition.author [
     fhir:index 0;
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-authorprimarysource" ];
       fhir:Extension.valueBoolean [ fhir:value "true"^^xsd:boolean ]     ];
     fhir:Reference.reference [ fhir:value "PractitionerRole/BESTAuthorRole" ]
  ];
  fhir:Composition.title [ fhir:value "ICSR Submission"];
  fhir:Composition.section [
     fhir:index 0;
     fhir:Composition.section.title [ fhir:value "Reaction/Event" ];
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS" ];
         fhir:Coding.code [ fhir:value "ReactionEvent" ]       ]     ];
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ];
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Allergic transfusion reaction</div>"     ];
     fhir:Composition.section.entry [
       fhir:index 0;
       fhir:Reference.reference [ fhir:value "AdverseEvent/FAERSExampleEvent" ]     ]
  ], [
     fhir:index 1;
     fhir:Composition.section.title [ fhir:value "Drug Information" ];
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS" ];
         fhir:Coding.code [ fhir:value "DrugInformation" ]       ]     ];
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ];
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Description code for blood products: E7003, Blood group and type: N/A Blood processing type: Apheresis PLATELETS|ACD-A&gt;PAS-C/XX/20-24C|ResLeu:&amp;lt;5E6|2nd container</div>"     ];
     fhir:Composition.section.entry [
       fhir:index 0;
       fhir:Reference.reference [ fhir:value "Procedure/FAERSExampleTransfusion" ]     ], [
       fhir:index 1;
       fhir:Reference.reference [ fhir:value "MedicationAdministration/FAERSEpinephrine" ]     ], [
       fhir:index 2;
       fhir:Reference.reference [ fhir:value "MedicationAdministration/FAERSDiphenhydramine" ]     ]
  ], [
     fhir:index 2;
     fhir:Composition.section.title [ fhir:value "Case Summary Narrative" ];
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS" ];
         fhir:Coding.code [ fhir:value "CaseSummaryNarrative" ]       ]     ];
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ];
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">Header: FDA CBER BEST Automated AE Reporting Prototype Case BEST Detection Phenotype Algorithm: Phenotype link: rules-cd BEST Certainty: Definite BEST Severity: Non-Severe BEST Imputability: Probable Form Type: 3500 Contact Method: Email Adverse Event: 1 Center to which the case is being routed to: CBER Whether the case is being sent to DQRS: false Whether the report is related to drugs or food/cosmetics: 1 Whether the blood report is of type Transfusion or Collection: 2 Patient Race Code: 2f, Blood group of patient: N/A, Onset location for reaction: MedStar Location Description code for blood products: N/A, Blood group and type: N/A Blood processing type: N/A Product available for evaluation: 2 Volume of transfusion: NI NHSN Workup: NI Preliminary investigation results: Developed rash &amp;#38; stridor following transfusion prbc for anemia. Tx with benadryl &amp;#38; epinephrine &amp;#38; sx improved., Adverse Event Type Imputability: Blood Transfusion - Certainty: Definite; Notes: 1. notes, Eval+Plan Note, For admission to Hosp with Dx Anemia. Transfuse PRBC now., Date 20020109; 2. notes, Eval+Plan Note, Patient has developed a new maculopapular rash following transfusion. Will give Benadryl 25 mg., Date 20020109; 3. notes, Eval+Plan Note, New onset Stridor following transfusion. Will give Epinephrine .5mg, and do transfusion Rxn workup, Date 20020109; 4. notes, Eval+Plan Note, RN note - Administered Benadryl 25mg IV for skin sx. After 30 min pt. reports some improvement in skin symptoms, Date 20020109 Labs, Vitals, and Tests: 1. labs, Diastolic Blood Pressure, 75.918 mm[Hg], Date 20020109; 2. labs, Systolic Blood Pressure, 123.08 mm[Hg], Date 20020109; 3. labs, Physical findings of Skin, generalized rash, Date 20020109; 4. labs, Respiratory status finding, Stridor, Date 20020109; Illness at Time of Vaccination: 1. illness, Problem, Anemia, Date 20020109;</div>"     ]
  ], [
     fhir:index 3;
     fhir:Composition.section.title [ fhir:value "Patient Information" ];
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS" ];
         fhir:Coding.code [ fhir:value "PatientInformation" ]       ]     ];
     fhir:Composition.section.entry [
       fhir:index 0;
       fhir:Reference.reference [ fhir:value "Observation/BESTPatientAgeGroup" ]     ]
  ], [
     fhir:index 4;
     fhir:Composition.section.title [ fhir:value "Relevant Medical History" ];
     fhir:Composition.section.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/CodeSystem/ICSRSectionCodeCS" ];
         fhir:Coding.code [ fhir:value "RelevantMedicalHistory" ]       ]     ];
     fhir:Composition.section.text [
       fhir:Narrative.status [ fhir:value "generated" ];
       fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">NI</div>"     ]
  ].

<Organization/FDA> a fhir:Organization;
  fhir:Resource.id [ fhir:value "FDA"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageorganization";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageorganization>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"FDA\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-messageorganization.html\">MessageHeader Organization</a></p></div><p><b>DepartmentName</b>: Office of Surveillance and Epidemiology</p><p><b>active</b>: true</p><p><b>type</b>: Regulatory Authority <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#2)</span></p><p><b>name</b>: FDA</p><p><b>telecom</b>: <a href=\"mailto:faersesub@fda.hhs.gov\">faersesub@fda.hhs.gov</a></p><p><b>address</b>: 10903 New Hampshire Avenue Silver Spring MD 20993 US </p><h3>Contacts</h3><table class=\"grid\"><tr><td>-</td><td><b>Name</b></td></tr><tr><td>*</td><td>FAERS </td></tr></table></div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-departmentname" ];
     fhir:Extension.valueString [ fhir:value "Office of Surveillance and Epidemiology" ]
  ];
  fhir:Organization.active [ fhir:value "true"^^xsd:boolean];
  fhir:Organization.type [
     fhir:index 0;
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.7" ];
       fhir:Coding.code [ fhir:value "2" ];
       fhir:Coding.display [ fhir:value "Regulatory Authority" ]     ]
  ];
  fhir:Organization.name [ fhir:value "FDA"];
  fhir:Organization.telecom [
     fhir:index 0;
     fhir:ContactPoint.system [ fhir:value "email" ];
     fhir:ContactPoint.value [ fhir:value "faersesub@fda.hhs.gov" ]
  ];
  fhir:Organization.address [
     fhir:index 0;
     fhir:Address.line [
       fhir:value "10903 New Hampshire Avenue";
       fhir:index 0     ];
     fhir:Address.city [ fhir:value "Silver Spring" ];
     fhir:Address.state [ fhir:value "MD" ];
     fhir:Address.postalCode [ fhir:value "20993" ];
     fhir:Address.country [ fhir:value "US" ]
  ];
  fhir:Organization.contact [
     fhir:index 0;
     fhir:Organization.contact.name [
       fhir:HumanName.given [
         fhir:value "FAERS";
         fhir:index 0       ]     ]
  ].

<Organization/BESTPrototype> a fhir:Organization;
  fhir:Resource.id [ fhir:value "BESTPrototype"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageorganization";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-messageorganization>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"BESTPrototype\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-messageorganization.html\">MessageHeader Organization</a></p></div><p><b>active</b>: true</p><p><b>name</b>: BEST-Prototype</p></div>"
  ];
  fhir:Organization.active [ fhir:value "true"^^xsd:boolean];
  fhir:Organization.name [ fhir:value "BEST-Prototype"].

<PractitionerRole/BESTAuthorRole> a fhir:PractitionerRole;
  fhir:Resource.id [ fhir:value "BESTAuthorRole"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitionerrole";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitionerrole>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"BESTAuthorRole\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-authorpractitionerrole.html\">PractitionerRole Author</a></p></div><p><b>practitioner</b>: <a href=\"#Practitioner_BESTAuthor\">See above (Practitioner/BESTAuthor)</a></p><p><b>organization</b>: <a href=\"#Organization_BESTPrototype\">See above (Organization/BESTPrototype)</a></p><p><b>code</b>: Physician <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#1)</span></p><p><b>telecom</b>: <a href=\"mailto:admin@admin.com\">admin@admin.com</a></p></div>"
  ];
  fhir:PractitionerRole.practitioner [
     fhir:Reference.reference [ fhir:value "Practitioner/BESTAuthor" ]
  ];
  fhir:PractitionerRole.organization [
     fhir:Reference.reference [ fhir:value "Organization/BESTPrototype" ]
  ];
  fhir:PractitionerRole.code [
     fhir:index 0;
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.6" ];
       fhir:Coding.code [ fhir:value "1" ];
       fhir:Coding.display [ fhir:value "Physician" ]     ]
  ];
  fhir:PractitionerRole.telecom [
     fhir:index 0;
     fhir:ContactPoint.system [ fhir:value "email" ];
     fhir:ContactPoint.value [ fhir:value "admin@admin.com" ]
  ].

<Practitioner/BESTAuthor> a fhir:Practitioner;
  fhir:Resource.id [ fhir:value "BESTAuthor"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitioner";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-authorpractitioner>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"BESTAuthor\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-authorpractitioner.html\">Practitioner Author</a></p></div><p><b>identifier</b>: id: NI</p><p><b>name</b>: NI </p></div>"
  ];
  fhir:Practitioner.identifier [
     fhir:index 0;
     fhir:Identifier.system [ fhir:value "http://hl7.org/fhir/sid/us-npi" ];
     fhir:Identifier.value [ fhir:value "NI" ]
  ];
  fhir:Practitioner.name [
     fhir:index 0;
     fhir:HumanName.family [ fhir:value "NI" ]
  ].

<Patient/BESTPatient> a fhir:Patient;
  fhir:Resource.id [ fhir:value "BESTPatient"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-patient";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-patient>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"BESTPatient\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-patient.html\">ICSR Patient</a></p></div><p><b>identifier</b>: id: 123456789</p><p><b>name</b>: CM </p><p><b>gender</b>: female</p><p><b>birthDate</b>: 1999-06-24</p></div>"
  ];
  fhir:Patient.identifier [
     fhir:index 0;
     fhir:Identifier.system [ fhir:value "http://hl7.org/fhir/sid/us-ssn" ];
     fhir:Identifier.value [ fhir:value "123456789" ]
  ];
  fhir:Patient.name [
     fhir:index 0;
     fhir:HumanName.family [ fhir:value "CM" ]
  ];
  fhir:Patient.gender [ fhir:value "female"];
  fhir:Patient.birthDate [ fhir:value "1999-06-24"^^xsd:date].

<Observation/BESTPatientAgeGroup> a fhir:Observation;
  fhir:Resource.id [ fhir:value "BESTPatientAgeGroup"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-patientagegroup";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-patientagegroup>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"BESTPatientAgeGroup\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-patientagegroup.html\">Descriptive Age Group for the Patient</a></p></div><p><b>status</b>: final</p><p><b>code</b>: Age group <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#46251-5)</span></p><p><b>subject</b>: <a href=\"#Patient_BESTPatient\">See above (Patient/BESTPatient)</a></p><p><b>value</b>: Adult <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (unknown#5)</span></p></div>"
  ];
  fhir:Observation.status [ fhir:value "final"];
  fhir:Observation.code [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       a loinc:46251-5;
       fhir:Coding.system [ fhir:value "http://loinc.org" ];
       fhir:Coding.code [ fhir:value "46251-5" ];
       fhir:Coding.display [ fhir:value "Age group" ]     ]
  ];
  fhir:Observation.subject [
     fhir:Reference.reference [ fhir:value "Patient/BESTPatient" ]
  ];
  fhir:Observation.valueCodeableConcept [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "urn:oid:2.16.840.1.113883.3.989.2.1.1.9" ];
       fhir:Coding.code [ fhir:value "5" ];
       fhir:Coding.display [ fhir:value "Adult" ]     ]
  ].

<AdverseEvent/FAERSExampleEvent> a fhir:AdverseEvent;
  fhir:Resource.id [ fhir:value "FAERSExampleEvent"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/faers-adverseevent";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/faers-adverseevent>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"FAERSExampleEvent\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-faers-adverseevent.html\">FAERS Adverse Event</a></p></div><p><b>AgeAtTimeOfOnset</b>: 1 a<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code a = 'a')</span></p><p><b>actuality</b>: actual</p><p><b>event</b>: Allergic transfusion reaction <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (meddra.org#10066173)</span></p><p><b>subject</b>: <a href=\"#Patient_BESTPatient\">See above (Patient/BESTPatient)</a></p><p><b>date</b>: 2000-01-01</p><p><b>seriousness</b>: Serious <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.0.0/CodeSystem-adverse-event-seriousness.html\">AdverseEventSeriousness</a>#serious)</span></p><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#Procedure_FAERSExampleTransfusion\">See above (Procedure/FAERSExampleTransfusion)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td>-</td><td><b>ProductRelatedness</b></td></tr><tr><td>*</td><td>Suspect</td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_FAERSEpinephrine\">See above (MedicationAdministration/FAERSEpinephrine)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td>-</td><td><b>ProductRelatedness</b></td></tr><tr><td>*</td><td>Concomitant</td></tr></table></blockquote><blockquote><p><b>suspectEntity</b></p><p><b>instance</b>: <a href=\"#MedicationAdministration_FAERSDiphenhydramine\">See above (MedicationAdministration/FAERSDiphenhydramine)</a></p><h3>Causalities</h3><table class=\"grid\"><tr><td>-</td><td><b>ProductRelatedness</b></td></tr><tr><td>*</td><td>Concomitant</td></tr></table></blockquote></div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-ageattimeofonset" ];
     fhir:Extension.valueAge [
       fhir:Quantity.value [ fhir:value "1"^^xsd:decimal ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "a" ]     ]
  ];
  fhir:AdverseEvent.actuality [ fhir:value "actual"];
  fhir:AdverseEvent.event [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://meddra.org" ];
       fhir:Coding.code [ fhir:value "10066173" ];
       fhir:Coding.display [ fhir:value "Allergic transfusion reaction" ]     ]
  ];
  fhir:AdverseEvent.subject [
     fhir:Reference.reference [ fhir:value "Patient/BESTPatient" ]
  ];
  fhir:AdverseEvent.date [
     fhir:value "2000-01-01"^^xsd:date;
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-eventenddate" ];
       fhir:Extension.valueDateTime [ fhir:value "2019-01-20"^^xsd:date ]     ], [
       fhir:index 1;
       fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-eventduration" ];
       fhir:Extension.valueDuration [
         fhir:Quantity.value [ fhir:value "19.05"^^xsd:decimal ];
         fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
         fhir:Quantity.code [ fhir:value "a" ]       ]     ]
  ];
  fhir:AdverseEvent.seriousness [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/adverse-event-seriousness" ];
       fhir:Coding.code [ fhir:value "serious" ]     ]
  ];
  fhir:AdverseEvent.suspectEntity [
     fhir:index 0;
     fhir:AdverseEvent.suspectEntity.instance [
       fhir:Reference.reference [ fhir:value "Procedure/FAERSExampleTransfusion" ]     ];
     fhir:AdverseEvent.suspectEntity.causality [
       fhir:index 0;
       fhir:AdverseEvent.suspectEntity.causality.productRelatedness [ fhir:value "Suspect" ]     ]
  ], [
     fhir:index 1;
     fhir:AdverseEvent.suspectEntity.instance [
       fhir:Reference.reference [ fhir:value "MedicationAdministration/FAERSEpinephrine" ]     ];
     fhir:AdverseEvent.suspectEntity.causality [
       fhir:index 0;
       fhir:AdverseEvent.suspectEntity.causality.productRelatedness [ fhir:value "Concomitant" ]     ]
  ], [
     fhir:index 2;
     fhir:AdverseEvent.suspectEntity.instance [
       fhir:Reference.reference [ fhir:value "MedicationAdministration/FAERSDiphenhydramine" ]     ];
     fhir:AdverseEvent.suspectEntity.causality [
       fhir:index 0;
       fhir:AdverseEvent.suspectEntity.causality.productRelatedness [ fhir:value "Concomitant" ]     ]
  ].

<Procedure/FAERSExampleTransfusion> a fhir:Procedure;
  fhir:Resource.id [ fhir:value "FAERSExampleTransfusion"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-transfusion";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-transfusion>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "extensions" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"FAERSExampleTransfusion\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-transfusion.html\">ICSR Transfusion</a></p></div><p><b>UsedProductAmount</b>: 1 unit<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code {unit} = '{unit}')</span></p><p><b>status</b>: completed</p><p><b>code</b>: 36430 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.0.0/CodeSystem-CPT.html\">Current Procedural Terminology (CPT&reg;)</a>#36430)</span></p><p><b>subject</b>: <a href=\"#Patient_BESTPatient\">See above (Patient/BESTPatient)</a></p><p><b>performed</b>: 2002-01-09</p><p><b>usedReference</b>: <span>: Apheresis PLATELETS|ACD-A&gt;PAS-C/XX/20-24C|ResLeu:&lt;5E6|2nd container</span></p></div>"
  ];
  fhir:DomainResource.extension [
     fhir:index 0;
     fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-usedproductamount" ];
     fhir:Extension.valueQuantity [
       fhir:Quantity.value [ fhir:value "1"^^xsd:decimal ];
       fhir:Quantity.unit [ fhir:value "unit" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "{unit}" ]     ]
  ];
  fhir:Procedure.status [ fhir:value "completed"];
  fhir:Procedure.code [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://www.ama-assn.org/go/cpt" ];
       fhir:Coding.code [ fhir:value "36430" ]     ]
  ];
  fhir:Procedure.subject [
     fhir:Reference.reference [ fhir:value "Patient/BESTPatient" ]
  ];
  fhir:Procedure.performedDateTime [ fhir:value "2002-01-09"^^xsd:date];
  fhir:Procedure.usedReference [
     fhir:index 0;
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-usedproduct" ];
       fhir:Extension.valueReference [
         fhir:Reference.reference [ fhir:value "BiologicallyDerivedProduct/FAERSBloodProduct" ]       ]     ];
     fhir:Reference.display [ fhir:value "Apheresis PLATELETS|ACD-A>PAS-C/XX/20-24C|ResLeu:<5E6|2nd container" ]
  ].

<BiologicallyDerivedProduct/FAERSBloodProduct> a fhir:BiologicallyDerivedProduct;
  fhir:Resource.id [ fhir:value "FAERSBloodProduct"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-bloodproduct";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-bloodproduct>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"FAERSBloodProduct\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-bloodproduct.html\">ICSR Blood Product</a></p></div><p><b>productCategory</b>: cells</p><p><b>productCode</b>: Apheresis PLATELETS|ACD-A&gt;PAS-C/XX/20-24C|ResLeu:&lt;5E6|2nd container <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (standardterminology#E7003)</span></p><h3>Collections</h3><table class=\"grid\"><tr><td>-</td><td><b>Extension</b></td></tr><tr><td>*</td><td></td></tr></table></div>"
  ];
  fhir:BiologicallyDerivedProduct.productCategory [ fhir:value "cells"];
  fhir:BiologicallyDerivedProduct.productCode [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "https://iccbba.org/standardterminology" ];
       fhir:Coding.code [ fhir:value "E7003" ];
       fhir:Coding.display [ fhir:value "Apheresis PLATELETS|ACD-A>PAS-C/XX/20-24C|ResLeu:<5E6|2nd container" ]     ]
  ];
  fhir:BiologicallyDerivedProduct.collection [
     fhir:Element.extension [
       fhir:index 0;
       fhir:Extension.url [ fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-ext-donationIdentificationNumber" ];
       fhir:Extension.valueIdentifier [
         fhir:Identifier.system [ fhir:value "http://example.org/bloodDonationNumber" ];
         fhir:Identifier.value [ fhir:value "G101610840386" ]       ]     ]
  ].

<MedicationAdministration/FAERSEpinephrine> a fhir:MedicationAdministration;
  fhir:Resource.id [ fhir:value "FAERSEpinephrine"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-medicationadministration";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-medicationadministration>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"FAERSEpinephrine\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-medicationadministration.html\">ICSR MedicationAdministration</a></p></div><p><b>status</b>: completed</p><p><b>medication</b>: Epinephrine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.0.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#3992)</span></p><p><b>subject</b>: <a href=\"#Patient_BESTPatient\">See above (Patient/BESTPatient)</a></p><p><b>effective</b>: 2002-01-09</p></div>"
  ];
  fhir:MedicationAdministration.status [ fhir:value "completed"];
  fhir:MedicationAdministration.medicationCodeableConcept [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ];
       fhir:Coding.code [ fhir:value "3992" ];
       fhir:Coding.display [ fhir:value "Epinephrine" ]     ]
  ];
  fhir:MedicationAdministration.subject [
     fhir:Reference.reference [ fhir:value "Patient/BESTPatient" ]
  ];
  fhir:MedicationAdministration.effectiveDateTime [ fhir:value "2002-01-09"^^xsd:date].

<MedicationAdministration/FAERSDiphenhydramine> a fhir:MedicationAdministration;
  fhir:Resource.id [ fhir:value "FAERSDiphenhydramine"];
  fhir:Resource.meta [
     fhir:Meta.profile [
       fhir:value "http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-medicationadministration";
       fhir:index 0;
       fhir:link <http://hl7.org/fhir/us/icsr-ae-reporting/StructureDefinition/icsr-medicationadministration>     ]
  ];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative</b></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource \"FAERSDiphenhydramine\" </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-icsr-medicationadministration.html\">ICSR MedicationAdministration</a></p></div><p><b>status</b>: completed</p><p><b>medication</b>: Diphenhydramine <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.0.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#3498)</span></p><p><b>subject</b>: <a href=\"#Patient_BESTPatient\">See above (Patient/BESTPatient)</a></p><p><b>effective</b>: 2002-01-09</p></div>"
  ];
  fhir:MedicationAdministration.status [ fhir:value "completed"];
  fhir:MedicationAdministration.medicationCodeableConcept [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ];
       fhir:Coding.code [ fhir:value "3498" ];
       fhir:Coding.display [ fhir:value "Diphenhydramine" ]     ]
  ];
  fhir:MedicationAdministration.subject [
     fhir:Reference.reference [ fhir:value "Patient/BESTPatient" ]
  ];
  fhir:MedicationAdministration.effectiveDateTime [ fhir:value "2002-01-09"^^xsd:date].

# - ontology header ------------------------------------------------------------

 a owl:Ontology;
  owl:imports fhir:fhir.ttl.