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<div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: ValueSet cns-depressant-medications</b></p><a name="cns-depressant-medications"> </a><a name="hccns-depressant-medications"> </a><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px"/><p style="margin-bottom: 0px">Profile: <a href="http://hl7.org/fhir/uv/crmi/STU1/StructureDefinition-crmi-expandedvalueset.html">CRMI Expanded ValueSet</a></p></div><p>This value set contains 116 concepts</p><table class="codes"><tr><td style="white-space:nowrap"><b>Code</b></td><td><b>System</b></td><td><b>Display</b></td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-904368"> </a> 904368</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>benzphetamine hydrochloride 50 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-904372"> </a> 904372</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>benzphetamine hydrochloride 25 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2698136"> </a> 2698136</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>{7 (sodium oxybate 4500 MG Granules for Oral Suspension [Lumryz]) / 14 (sodium oxybate 6000 MG Granules for Oral Suspension [Lumryz]) / 7 (sodium oxybate 7500 MG Granules for Oral Suspension [Lumryz]) } Pack [Lumryz 28-Day Starter Pack]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2698135"> </a> 2698135</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>{7 (sodium oxybate 4500 MG Granules for Oral Suspension) / 14 (sodium oxybate 6000 MG Granules for Oral Suspension) / 7 (sodium oxybate 7500 MG Granules for Oral Suspension) } Pack</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2393794"> </a> 2393794</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>calcium oxybate 234 MG/ML / magnesium oxybate 96 MG/ML / potassium oxybate 130 MG/ML / sodium oxybate 40 MG/ML Oral Solution [Xywav]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2636828"> </a> 2636828</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sodium oxybate 4500 MG Granules for Oral Suspension [Lumryz]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2636832"> </a> 2636832</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sodium oxybate 6000 MG Granules for Oral Suspension [Lumryz]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2636836"> </a> 2636836</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sodium oxybate 7500 MG Granules for Oral Suspension [Lumryz]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2636840"> </a> 2636840</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sodium oxybate 9000 MG Granules for Oral Suspension [Lumryz]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-352257"> </a> 352257</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sodium oxybate 500 MG/ML Oral Solution [Xyrem]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2393795"> </a> 2393795</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>calcium oxybate 234 MG/ML / magnesium oxybate 96 MG/ML / potassium oxybate 130 MG/ML / sodium oxybate 40 MG/ML Oral Solution</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2636822"> </a> 2636822</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sodium oxybate 4500 MG Granules for Oral Suspension</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2636830"> </a> 2636830</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sodium oxybate 6000 MG Granules for Oral Suspension</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2636834"> </a> 2636834</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sodium oxybate 7500 MG Granules for Oral Suspension</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2636838"> </a> 2636838</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sodium oxybate 9000 MG Granules for Oral Suspension</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-349482"> </a> 349482</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sodium oxybate 500 MG/ML Oral Solution</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-208919"> </a> 208919</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>desflurane 1000 MG/ML Inhalation Solution [Suprane]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-562366"> </a> 562366</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>desflurane 1000 MG/ML Inhalation Solution</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-994071"> </a> 994071</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR phendimetrazine tartrate 105 MG Extended Release Oral Capsule [Melfiat]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-979543"> </a> 979543</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR phendimetrazine tartrate 105 MG Extended Release Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-979549"> </a> 979549</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phendimetrazine tartrate 35 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-978662"> </a> 978662</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>diethylpropion hydrochloride 25 MG Oral Tablet [Tenuate]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-978686"> </a> 978686</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR diethylpropion hydrochloride 75 MG Extended Release Oral Tablet [Tenuate]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-978654"> </a> 978654</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>diethylpropion hydrochloride 25 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-978668"> </a> 978668</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR diethylpropion hydrochloride 75 MG Extended Release Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1245044"> </a> 1245044</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sevoflurane 1000 MG/ML Inhalation Solution [SevoFlo]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2697457"> </a> 2697457</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sevoflurane 1000 MG/ML Inhalation Solution [Sevospire]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-541963"> </a> 541963</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sevoflurane 1000 MG/ML Inhalation Solution [Ultane]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-997618"> </a> 997618</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sevoflurane 1000 MG/ML Inhalation Solution [Petrem]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-997625"> </a> 997625</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sevoflurane 1000 MG/ML Inhalation Solution [Sojourn]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-200243"> </a> 200243</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>sevoflurane 1000 MG/ML Inhalation Solution</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-313489"> </a> 313489</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>trimethobenzamide 100 MG Rectal Suppository</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-313492"> </a> 313492</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>trimethobenzamide 200 MG Rectal Suppository</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-860745"> </a> 860745</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>benzocaine 0.02 MG/MG / trimethobenzamide hydrochloride 200 MG Rectal Suppository</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-860752"> </a> 860752</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>trimethobenzamide hydrochloride 100 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-860767"> </a> 860767</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>trimethobenzamide hydrochloride 250 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-860771"> </a> 860771</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>trimethobenzamide hydrochloride 300 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-828696"> </a> 828696</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 5 MG/ACTUAT Oral Spray [Zolpimist]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-836645"> </a> 836645</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 10 MG Sublingual Tablet [Edluar]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-836649"> </a> 836649</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 5 MG Sublingual Tablet [Edluar]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-854875"> </a> 854875</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 10 MG Oral Tablet [Ambien]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-854878"> </a> 854878</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 5 MG Oral Tablet [Ambien]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-854882"> </a> 854882</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 12.5 MG Extended Release Oral Tablet [Ambien]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-854896"> </a> 854896</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 6.25 MG Extended Release Oral Tablet [Ambien]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1232194"> </a> 1232194</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 1.75 MG Sublingual Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1232202"> </a> 1232202</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 3.5 MG Sublingual Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2637353"> </a> 2637353</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 7.5 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-828692"> </a> 828692</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 5 MG/ACTUAT Oral Spray</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-836641"> </a> 836641</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 10 MG Sublingual Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-836647"> </a> 836647</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 5 MG Sublingual Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-854873"> </a> 854873</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 10 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-854876"> </a> 854876</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 5 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-854880"> </a> 854880</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 12.5 MG Extended Release Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-854885"> </a> 854885</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 5 MG Disintegrating Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-854886"> </a> 854886</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 10 MG Disintegrating Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-854894"> </a> 854894</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zolpidem tartrate 6.25 MG Extended Release Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1732674"> </a> 1732674</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>dexmedetomidine 0.00009 MG/MG Oral Gel [Sileo]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2601126"> </a> 2601126</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>dexmedetomidine 0.12 MG Sublingual Film [Igalmi]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2601131"> </a> 2601131</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>dexmedetomidine 0.18 MG Sublingual Film [Igalmi]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1732668"> </a> 1732668</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>dexmedetomidine 0.00009 MG/MG Oral Gel</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2601119"> </a> 2601119</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>dexmedetomidine 0.12 MG Sublingual Film</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2601129"> </a> 2601129</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>dexmedetomidine 0.18 MG Sublingual Film</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1540984"> </a> 1540984</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>isoflurane 999 MG/ML Inhalation Solution [Fluriso]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1549863"> </a> 1549863</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>isoflurane 999 MG/ML Inhalation Solution [IsoSol]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2628931"> </a> 2628931</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>isoflurane 999 MG/ML Inhalation Solution [Isospire]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-542355"> </a> 542355</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>isoflurane 999 MG/ML Inhalation Solution [Terrell]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-542358"> </a> 542358</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>isoflurane 999 MG/ML Inhalation Solution [Forane]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-542347"> </a> 542347</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>isoflurane 999 MG/ML Inhalation Solution</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1251685"> </a> 1251685</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Oral Tablet [Verticalm]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1673797"> </a> 1673797</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Oral Tablet [Wal-Dram 2]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1800794"> </a> 1800794</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Disintegrating Oral Tablet [Wal-Dram 2]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2110527"> </a> 2110527</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Oral Tablet [Dramamine Nausea Relief]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2176732"> </a> 2176732</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Chewable Tablet [Dramamine Less Drowsy]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2273509"> </a> 2273509</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Chewable Tablet [Antivert]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2540687"> </a> 2540687</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Disintegrating Oral Tablet [Zentrip]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995626"> </a> 995626</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 12.5 MG Oral Tablet [Antivert]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995634"> </a> 995634</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Chewable Tablet [Bonine]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995668"> </a> 995668</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Oral Tablet [Antivert]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995688"> </a> 995688</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 50 MG Oral Tablet [Antivert]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995726"> </a> 995726</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Oral Tablet [Dramamine Less Drowsy]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1663815"> </a> 1663815</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Disintegrating Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-2632643"> </a> 2632643</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 50 MG Chewable Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995624"> </a> 995624</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 12.5 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995632"> </a> 995632</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Chewable Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995666"> </a> 995666</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 25 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995682"> </a> 995682</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 30 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995686"> </a> 995686</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 50 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-995753"> </a> 995753</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>meclizine hydrochloride 12.5 MG Oral Lozenge</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-977861"> </a> 977861</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>methamphetamine hydrochloride 5 MG Oral Tablet [Desoxyn]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-977860"> </a> 977860</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>methamphetamine hydrochloride 5 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-313761"> </a> 313761</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zaleplon 10 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-313762"> </a> 313762</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>zaleplon 5 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1302833"> </a> 1302833</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR phentermine 7.5 MG / topiramate 46 MG Extended Release Oral Capsule [Qsymia]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1302845"> </a> 1302845</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR phentermine 3.75 MG / topiramate 23 MG Extended Release Oral Capsule [Qsymia]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1302856"> </a> 1302856</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR phentermine 15 MG / topiramate 92 MG Extended Release Oral Capsule [Qsymia]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1313061"> </a> 1313061</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR phentermine 11.25 MG / topiramate 69 MG Extended Release Oral Capsule [Qsymia]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1810304"> </a> 1810304</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 8 MG Oral Tablet [Lomaira]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-803350"> </a> 803350</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 37.5 MG Oral Capsule [Adipex-P]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-803354"> </a> 803354</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 37.5 MG Oral Tablet [Adipex-P]</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1112982"> </a> 1112982</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 15 MG Disintegrating Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1112987"> </a> 1112987</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 30 MG Disintegrating Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1249083"> </a> 1249083</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 37.5 MG Disintegrating Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1302827"> </a> 1302827</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR phentermine 7.5 MG / topiramate 46 MG Extended Release Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1302839"> </a> 1302839</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR phentermine 3.75 MG / topiramate 23 MG Extended Release Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1302850"> </a> 1302850</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR phentermine 15 MG / topiramate 92 MG Extended Release Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-1313059"> </a> 1313059</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>24 HR phentermine 11.25 MG / topiramate 69 MG Extended Release Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-803348"> </a> 803348</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 37.5 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-803353"> </a> 803353</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 37.5 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-826131"> </a> 826131</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 18.8 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-826586"> </a> 826586</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine resin 15 MG Extended Release Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-826600"> </a> 826600</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine resin 15 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-826832"> </a> 826832</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine resin 30 MG Extended Release Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-826910"> </a> 826910</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine resin 30 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-826919"> </a> 826919</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 8 MG Oral Tablet</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-900038"> </a> 900038</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 30 MG Oral Capsule</td></tr><tr><td style="white-space:nowrap"><a name="cns-depressant-medications-http://www.nlm.nih.gov/research/umls/rxnorm-968766"> </a> 968766</td><td>http://www.nlm.nih.gov/research/umls/rxnorm</td><td>phentermine hydrochloride 15 MG Oral Capsule</td></tr></table></div>
</text>
<extension url="http://hl7.org/fhir/StructureDefinition/artifact-author">
<valueContactDetail>
<name value="MD Partners, Inc."/>
<telecom>
<system value="email"/>
<value value="info@mdpartners.com"/>
</telecom>
</valueContactDetail>
</extension>
<extension url="http://hl7.org/fhir/StructureDefinition/valueset-warning">
<valueMarkdown
value="This value set contains a point-in-time expansion enumerating the codes that meet the value set intent. As new versions of the code systems used by the value set are released, the contents of this expansion will need to be updated to incorporate newly defined codes that meet the value set intent. Before, and periodically during production use, the value set expansion contents SHOULD be updated."/>
</extension>
<extension
url="http://hl7.org/fhir/StructureDefinition/valueset-rules-text">
<valueMarkdown
value="https://mor.nlm.nih.gov/RxMix/ Script:
Step 1a
Create Batch text input file (CNSD.txt) with following DailyMed identifier (for the concept "Central Nervous System Depressants") as an input within the file:
N0000175728
Step 1b
Submit batch job using the above CNSD.txt file to following workflow by uploading file (CNSD-wf.config) with the following in the file: <WFE><filteredOutputs>RXCUI|name|term_type</filteredOutputs><input>NOINPUT</input><FS><service>NOINPUT</service><function>getClassMembers</function><level>0</level><paramSize>5</paramSize><param order ='0'>?</param><param order ='1'>DAILYMED</param><param order ='2'>N/A</param><param order ='3'>0</param><param order ='4'>IN,MIN,PIN</param></FS><FS><service>NOINPUT</service><function>getRelatedByType</function><level>1</level><paramSize>2</paramSize><param order ='0'>?</param><param order ='1'>BPCK,GPCK,SBD,SCD</param></FS></WFE>
Step 2
To remove all cough and bowel transit formulation codes and to remove the injectable codes filter out all codes with the following strings:
Ingredient strings:
Guaifenesin, Chlorpheniramine, Pseudoephedrine, Brompheniramine, Phenylephrine, Phenylpropanolamine, Promethazine, Bromodiphenhydramine, guaiacolsulfonate, homatropine
Form strings:
inject, cartridge, syringe"/>
</extension>
<extension
url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
<valueCode value="cds"/>
</extension>
<extension
url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">
<valueInteger value="2">
<extension
url="http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom">
<valueCanonical
value="http://hl7.org/fhir/us/cdc-opioid-cpg/ImplementationGuide/hl7.fhir.us.cdc-opioid-cpg"/>
</extension>
</valueInteger>
</extension>
<extension
url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
<valueCode value="trial-use">
<extension
url="http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom">
<valueCanonical
value="http://hl7.org/fhir/us/cdc-opioid-cpg/ImplementationGuide/hl7.fhir.us.cdc-opioid-cpg"/>
</extension>
</valueCode>
</extension>
<url
value="http://fhir.org/guides/cdc/opioid-cds/ValueSet/cns-depressant-medications"/>
<version value="1.0.0-ballot"/>
<name value="CNS_DEPRESSANT_MEDICATIONS"/>
<title value="CNS depressant medications"/>
<status value="active"/>
<experimental value="false"/>
<date value="2025-02-24T13:06:43-07:00"/>
<publisher value="HL7 International / Clinical Decision Support"/>
<contact>
<telecom>
<system value="url"/>
<value value="http://www.hl7.org/Special/committees/dss"/>
</telecom>
</contact>
<description
value="Medications considered to have an ingredient considered to be a CNS depressant, some of which may be mild. Removed from this set are cough medications and bowl transit modifiers."/>
<jurisdiction>
<coding>
<system value="urn:iso:std:iso:3166"/>
<code value="US"/>
</coding>
</jurisdiction>
<copyright value="© CDC 2016+."/>
<expansion>
<timestamp value="2025-02-24T13:06:43-07:00"/>
<total value="116"/>
<parameter>
<name value="system-version"/>
<valueString value="03042024"/>
</parameter>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="904368"/>
<display value="benzphetamine hydrochloride 50 MG Oral Tablet"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="904372"/>
<display value="benzphetamine hydrochloride 25 MG Oral Tablet"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2698136"/>
<display
value="{7 (sodium oxybate 4500 MG Granules for Oral Suspension [Lumryz]) / 14 (sodium oxybate 6000 MG Granules for Oral Suspension [Lumryz]) / 7 (sodium oxybate 7500 MG Granules for Oral Suspension [Lumryz]) } Pack [Lumryz 28-Day Starter Pack]"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2698135"/>
<display
value="{7 (sodium oxybate 4500 MG Granules for Oral Suspension) / 14 (sodium oxybate 6000 MG Granules for Oral Suspension) / 7 (sodium oxybate 7500 MG Granules for Oral Suspension) } Pack"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2393794"/>
<display
value="calcium oxybate 234 MG/ML / magnesium oxybate 96 MG/ML / potassium oxybate 130 MG/ML / sodium oxybate 40 MG/ML Oral Solution [Xywav]"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2636828"/>
<display
value="sodium oxybate 4500 MG Granules for Oral Suspension [Lumryz]"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2636832"/>
<display
value="sodium oxybate 6000 MG Granules for Oral Suspension [Lumryz]"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2636836"/>
<display
value="sodium oxybate 7500 MG Granules for Oral Suspension [Lumryz]"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2636840"/>
<display
value="sodium oxybate 9000 MG Granules for Oral Suspension [Lumryz]"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="352257"/>
<display value="sodium oxybate 500 MG/ML Oral Solution [Xyrem]"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2393795"/>
<display
value="calcium oxybate 234 MG/ML / magnesium oxybate 96 MG/ML / potassium oxybate 130 MG/ML / sodium oxybate 40 MG/ML Oral Solution"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2636822"/>
<display value="sodium oxybate 4500 MG Granules for Oral Suspension"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2636830"/>
<display value="sodium oxybate 6000 MG Granules for Oral Suspension"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2636834"/>
<display value="sodium oxybate 7500 MG Granules for Oral Suspension"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="2636838"/>
<display value="sodium oxybate 9000 MG Granules for Oral Suspension"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="349482"/>
<display value="sodium oxybate 500 MG/ML Oral Solution"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="208919"/>
<display value="desflurane 1000 MG/ML Inhalation Solution [Suprane]"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="562366"/>
<display value="desflurane 1000 MG/ML Inhalation Solution"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="994071"/>
<display
value="24 HR phendimetrazine tartrate 105 MG Extended Release Oral Capsule [Melfiat]"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
<code value="979543"/>
<display
value="24 HR phendimetrazine tartrate 105 MG Extended Release Oral Capsule"/>
</contains>
<contains>
<system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
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