HL7 FHIR Implementation Guide: Breast Cancer Data, Release 1 - US Realm (Draft for Comment 2)
This page is part of the Breast Cancer Data Logical Models and FHIR Profiles (v0.2.0: STU 1 Draft) based on FHIR R3. . For a full list of available versions, see the Directory of published versions 
The official URL for this logical model is:
http://hl7.org/fhir/us/breastcancer/StructureDefinition/oncology-HER2ReceptorStatus-model
HER2 receptor status. HER2 is a member of the human epidermal growth factor receptor family of proteins and is encoded by the ERBB2 oncogene. HER2 is overexpressed in 20-30% of breast tumors, and is associated with an aggressive clinical course and poor prognosis. HER2 status (positive=present or overexpressed; negative=absent) is a factor in determining prognosis and treatment options.
This logical model was published on Fri Aug 17 00:00:00 AEST 2018 as a draft by The HL7 Cancer Interoperability Group sponsored by Clinical Interoperability Council Work Group (CIC).
View the corresponding HER2ReceptorStatusProfile profile.
| Name | Flags | Card. | Type | Description & Constraints |
|---|---|---|---|---|
  oncology-HER2ReceptorStatus-model | 0..* | |||
  personOfRecord | 1..1 | Reference(BC PersonOfRecord Logical Model) | The person this entry belongs to. | |
 laboratoryObservationTopic | 1..1 | BackboneElement | The topic composition for laboratory observations. A specimen is required, anatomical location is excluded (since the specimen indicates the collection body site). Also includes a diagnostic service (indicating the type of laboratory), not present in general observations. | |
 topicCode | 1..1 | Coding | The concept representing the finding or action that is the topic of the statement. | |
 extension | 0..* | Extension | Additional Content defined by implementations Slice: Unordered, Open by value:url | |
 system | Σ | 1..1 | uri | Identity of the terminology system Fixed Value: http://loinc.org |
| version | Σ | 0..1 | string | Version of the system - if relevant |
| code | Σ | 1..1 | code | Symbol in syntax defined by the system Fixed Value: 48676-1 |
| display | Σ | 0..1 | string | Representation defined by the system |
 userSelected | Σ | 0..1 | boolean | If this coding was chosen directly by the user |
| details | 0..1 | string | A text note containing additional details, explanation, description, comment, or summarization. Details can discuss, support, explain changes to, or dispute information. | |
| category | 1..* | Coding | A class or division of people or things having particular shared characteristics | |
| extension | 0..* | Extension | Additional Content defined by implementations Slice: Unordered, Open by value:url | |
| system | Σ | 1..1 | uri | Identity of the terminology system Fixed Value: http://hl7.org/fhir/observation-category |
| version | Σ | 0..1 | string | Version of the system - if relevant |
| code | Σ | 1..1 | code | Symbol in syntax defined by the system Fixed Value: laboratory |
| display | Σ | 0..1 | string | Representation defined by the system |
| userSelected | Σ | 0..1 | boolean | If this coding was chosen directly by the user |
| breastSpecimen | 1..1 | Reference(BC BreastSpecimen Logical Model) | Specimen resulting from biopsy or excision of breast and surrounding tissue. | |
| panelMembers | 0..1 | BackboneElement | PanelMembers represent the elements of a group of a related but independent evaluations. | |
| observation | 0..1 | Represents the result of evaluations (measurements, tests, or questions) that have been performed. | ||
 hER2byIHC | 0..* | Reference(BC HER2byIHC Logical Model) | HER2 presence in Breast cancer specimen by Immunohistochemistry (IHC). | |
| hER2byFISH | 0..* | Reference(BC HER2byFISH Logical Model) | HER2 receptor status as determined by single-probe or dual-probe Fluorescence In Situ Hybridization (FISH). | |
| diagnosticService | 0..* | Coding | The service completing the observations, e.g. biochemistry, microbiology, blood bank. | |
| extension | 0..* | Extension | Additional Content defined by implementations Slice: Unordered, Open by value:url | |
| system | Σ | 1..1 | uri | Identity of the terminology system Fixed Value: http://hl7.org/fhir/v2/0074 |
| version | Σ | 0..1 | string | Version of the system - if relevant |
| code | Σ | 1..1 | code | Symbol in syntax defined by the system Fixed Value: PAT |
| display | Σ | 0..1 | string | Representation defined by the system |
| userSelected | Σ | 0..1 | boolean | If this coding was chosen directly by the user |
| observationContext | 1..1 | BackboneElement | Context for recording an evaluation result, used to indicate an evaluation has been made. | |
| contextCode | 1..1 | Coding | A code representing the ontological status of the statement, e.g., whether it exists, does not exist, is planned, etc. | |
| extension | 0..* | Extension | Additional Content defined by implementations Slice: Unordered, Open by value:url | |
| system | Σ | 1..1 | uri | Identity of the terminology system Fixed Value: http://snomed.info/sct |
| version | Σ | 0..1 | string | Version of the system - if relevant |
| code | Σ | 1..1 | code | Symbol in syntax defined by the system Fixed Value: 424975005 |
| display | Σ | 0..1 | string | Representation defined by the system |
| userSelected | Σ | 0..1 | boolean | If this coding was chosen directly by the user |
 encounter | 0..1 | http://hl7.org/fhir/us/breastcancer/StructureDefinition/cimi-encounter-Encounter-model | A description of an interaction between a patient and healthcare provider(s) for the purpose of providing healthcare service(s) or assessing the health status of a patient. | |
| interpretation | 0..1 | Coding | A clinical interpretation of a finding (applies to both assertions and observation). Binding: Observation Interpretation Codes (extensible) | |
| findingStatus | 1..1 | code | Indicates whether the finding is preliminary, amended, final, etc. Binding: ObservationStatus (required) | |
 relevantTime | 0..1 | dateTime, http://hl7.org/fhir/us/breastcancer/StructureDefinition/shr-core-TimePeriod-model | The time or time period that the finding addresses. | |
| resultValue | 0..1 | Coding | The finding itself, such as the blood pressure value recorded. Binding: BC PositiveNegativeEquivocalIndeterminateVS ValueSet (required) | |
| exceptionValue | 0..1 | Coding | Reason that a value associated with a test or other finding is missing. Binding: DataAbsentReason (extensible) | |
| deltaFlag | 0..1 | Coding | Indicator of significant change (delta) from the last or previous measurement. Binding: BC DeltaFlagVS ValueSet (required) | |
| issued | 0..1 | instant | The date and time this observation was made available to providers, typically after the results have been reviewed and verified. | |
| observer | 0..* | Reference(BC Practitioner Logical Model | BC Organization Logical Model | BC Patient Logical Model | BC RelatedPerson Logical Model) | The person or organization who observed or informed the reporter about the characteristic, potentially the clinician, the patient, or a related person. | |
| Documentation for this format | ||||
Downloads: StructureDefinition: (XML, JSON, TTL)
| Path | Name | Conformance | ValueSet |
| oncology-HER2ReceptorStatus-model.observationContext.interpretation | Observation Interpretation Codes | extensible | Observation Interpretation Codes |
| oncology-HER2ReceptorStatus-model.observationContext.findingStatus | ObservationStatus | required | ObservationStatus |
| oncology-HER2ReceptorStatus-model.observationContext.resultValue | BC PositiveNegativeEquivocalIndeterminateVS ValueSet | required | PositiveNegativeEquivocalIndeterminateVS |
| oncology-HER2ReceptorStatus-model.observationContext.exceptionValue | DataAbsentReason | extensible | DataAbsentReason |
| oncology-HER2ReceptorStatus-model.observationContext.deltaFlag | BC DeltaFlagVS ValueSet | required | DeltaFlagVS |