<?xml version="1.0" encoding="UTF-8"?><MedicationRequest xmlns="http://hl7.org/fhir"><id value="medrx0317"/><text><status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: MedicationRequest</b><a name="medrx0317"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource MedicationRequest &quot;medrx0317&quot; </p></div><p><b>identifier</b>: id: 12345689 (use: OFFICIAL)</p><p><b>status</b>: completed</p><p><b>intent</b>: order</p><h3>Medications</h3><table class="grid"><tr><td>-</td><td><b>Reference</b></td></tr><tr><td>*</td><td><a name="med0303"> </a><blockquote><p/><p><a name="med0303"> </a></p><p><b>code</b>: Alemtuzumab 10mg/ml (Lemtrada) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.1.0/CodeSystem-v3-rxNorm.html">RxNorm</a>#1594660)</span></p></blockquote></td></tr></table><p><b>subject</b>: <a href="patient-example-a.html">Patient/pat1: Donald Duck</a> &quot;Donald DUCK&quot;</p><p><b>authoredOn</b>: 2015-01-15</p><p><b>requester</b>: <a href="practitioner-example-f007-sh.html">Practitioner/f007: Patrick Pump</a> &quot;Simone HEPS&quot;</p><h3>Reasons</h3><table class="grid"><tr><td>-</td><td><b>Concept</b></td></tr><tr><td>*</td><td>Chronic Lymphoid Leukemia (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#92814006)</span></td></tr></table><blockquote><p><b>dosageInstruction</b></p><p><b>sequence</b>: 1</p><p><b>text</b>: Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk</p><p><b>additionalInstruction</b>: Rapidly increase dose until tolerated <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Administer on alternate days <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>timing</b>: Duration 12weeks, 3 per 1 weeks</p><p><b>route</b>: Intravenous route (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#47625008)</span></p><p><b>method</b>: Inject - dosing instruction imperative (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#422145002)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote></blockquote><blockquote><p><b>dosageInstruction</b></p><p><b>sequence</b>: 2</p><p><b>text</b>: Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk</p><p><b>additionalInstruction</b>: Rapidly increase dose until tolerated <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Administer on alternate days <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>timing</b>: Duration 12weeks, 3 per 1 weeks</p><p><b>route</b>: Intravenous route (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#47625008)</span></p><p><b>method</b>: Inject - dosing instruction imperative (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#422145002)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote></blockquote><blockquote><p><b>dosageInstruction</b></p><p><b>sequence</b>: 3</p><p><b>text</b>: Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk</p><p><b>additionalInstruction</b>: Rapidly increase dose until tolerated <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span>, Administer on alternate days <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><p><b>timing</b>: Duration 12weeks, 3 per 1 weeks</p><p><b>route</b>: Intravenous route (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#47625008)</span></p><p><b>method</b>: Inject - dosing instruction imperative (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a>#422145002)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote></blockquote></div></text><contained><Medication><id value="med0303"/><code><coding><system value="http://www.nlm.nih.gov/research/umls/rxnorm"/><code value="1594660"/><display value="Alemtuzumab 10mg/ml (Lemtrada)"/></coding></code></Medication></contained><identifier><use value="official"/><system value="http://www.bmc.nl/portal/prescriptions"/><value value="12345689"/></identifier><status value="completed"/><intent value="order"/><medication><reference><reference value="#med0303"/></reference></medication><subject>  <!--    Linked to the resource patient who needs the medication    --><reference value="Patient/pat1"/><display value="Donald Duck"/></subject><authoredOn value="2015-01-15"/><requester><reference value="Practitioner/f007"/><display value="Patrick Pump"/></requester><reason><concept><coding><system value="http://snomed.info/sct"/><code value="92814006"/><display value="Chronic Lymphoid Leukemia (disorder)"/></coding></concept></reason><dosageInstruction><sequence value="1"/><text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/><additionalInstruction><text value="Rapidly increase dose until tolerated"/></additionalInstruction><additionalInstruction><text value="Administer on alternate days"/></additionalInstruction><timing><repeat><duration value="12"/><durationUnit value="wk"/><frequency value="3"/><period value="1"/><periodUnit value="wk"/></repeat></timing><route><coding><system value="http://snomed.info/sct"/><code value="47625008"/><display value="Intravenous route (qualifier value)"/></coding></route><method><coding><system value="http://snomed.info/sct"/><code value="422145002"/><display value="Inject - dosing instruction imperative (qualifier value)"/></coding></method><doseAndRate><type><coding><system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/><code value="ordered"/><display value="Ordered"/></coding></type><doseQuantity><value value="3"/><unit value="mg"/><system value="http://unitsofmeasure.org"/><code value="mg"/></doseQuantity></doseAndRate></dosageInstruction><dosageInstruction><sequence value="2"/><text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/><additionalInstruction><text value="Rapidly increase dose until tolerated"/></additionalInstruction><additionalInstruction><text value="Administer on alternate days"/></additionalInstruction><timing><repeat><duration value="12"/><durationUnit value="wk"/><frequency value="3"/><period value="1"/><periodUnit value="wk"/></repeat></timing><route><coding><system value="http://snomed.info/sct"/><code value="47625008"/><display value="Intravenous route (qualifier value)"/></coding></route><method><coding><system value="http://snomed.info/sct"/><code value="422145002"/><display value="Inject - dosing instruction imperative (qualifier value)"/></coding></method><doseAndRate><type><coding><system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/><code value="ordered"/><display value="Ordered"/></coding></type><doseQuantity><value value="10"/><unit value="mg"/><system value="http://unitsofmeasure.org"/><code value="mg"/></doseQuantity></doseAndRate></dosageInstruction><dosageInstruction><sequence value="3"/><text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk"/><additionalInstruction><text value="Rapidly increase dose until tolerated"/></additionalInstruction><additionalInstruction><text value="Administer on alternate days"/></additionalInstruction><timing><repeat><duration value="12"/><durationUnit value="wk"/><frequency value="3"/><period value="1"/><periodUnit value="wk"/></repeat></timing><route><coding><system value="http://snomed.info/sct"/><code value="47625008"/><display value="Intravenous route (qualifier value)"/></coding></route><method><coding><system value="http://snomed.info/sct"/><code value="422145002"/><display value="Inject - dosing instruction imperative (qualifier value)"/></coding></method><doseAndRate><type><coding><system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/><code value="ordered"/><display value="Ordered"/></coding></type><doseQuantity><value value="30"/><unit value="mg"/><system value="http://unitsofmeasure.org"/><code value="mg"/></doseQuantity></doseAndRate></dosageInstruction></MedicationRequest>