This page is part of the FHIR Specification (v4.0.1: R4 - Mixed Normative and STU) in it's permanent home (it will always be available at this URL). The current version which supercedes this version is 5.0.0. For a full list of available versions, see the Directory of published versions . Page versions: R4B R4 R3

• Content
• Detailed Descriptions
• Mappings
• XML
• JSON

Extension: CopyNumberEvent

URL for this extension:

http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent

Status: draft. Extension maintained by: Health Level Seven International (Clinical Genomics)

A variation that increases or decreases the copy number of a given region (SO:0001019). Values: amplification/deletion/LOH.

Comment:

Loss of heterozygosity (LOH) is a functional variant whereby the sequence alteration causes a loss of function of one allele of a gene (SO:0001786).

Context of Use: Use on Element ID Observation

Extension Content

• Summary
• Full Structure
• XML
• JSON
• All

Summary

Name	Flags	Card.	Type	Description & Constraints
CopyNumberEvent		0..1	CodeableConcept	URL = http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent CopyNumberEvent: A variation that increases or decreases the copy number of a given region (SO:0001019). Values: amplification/deletion/LOH. Use on Element ID Observation
Documentation for this format

Full Structure

Name	Flags	Card.	Type	Description & Constraints
extension		0..1	Extension	URL = http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent CopyNumberEvent: A variation that increases or decreases the copy number of a given region (SO:0001019). Values: amplification/deletion/LOH. Use on Element ID Observation
extension	I	0..0
url		1..1	uri	"http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent"
value[x]	I	1..1	CodeableConcept	Value of extension
Documentation for this format

XML Template

<!-- CopyNumberEvent -->

<extension xmlns="http://hl7.org/fhir"
     url="http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent" >
  <!-- from Element: extension -->
 <valueCodeableConcept><!--  1..1 CodeableConcept Value of extension --></valueCodeableConcept>
</extension>

JSON Template

{ // CopyNumberEvent
  // from Element: extension
    "extension" : [ //  sliced by value:url  in the specified order, Open ]
    "url" : "http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent", // R! 
    "valueCodeableConcept" : { CodeableConcept } // C? R! Value of extension
  }

Summary

Name	Flags	Card.	Type	Description & Constraints
CopyNumberEvent		0..1	CodeableConcept	URL = http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent CopyNumberEvent: A variation that increases or decreases the copy number of a given region (SO:0001019). Values: amplification/deletion/LOH. Use on Element ID Observation
Documentation for this format

Full Structure

Name	Flags	Card.	Type	Description & Constraints
extension		0..1	Extension	URL = http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent CopyNumberEvent: A variation that increases or decreases the copy number of a given region (SO:0001019). Values: amplification/deletion/LOH. Use on Element ID Observation
extension	I	0..0
url		1..1	uri	"http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent"
value[x]	I	1..1	CodeableConcept	Value of extension
Documentation for this format

XML Template

<!-- CopyNumberEvent -->

<extension xmlns="http://hl7.org/fhir"
     url="http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent" >
  <!-- from Element: extension -->
 <valueCodeableConcept><!--  1..1 CodeableConcept Value of extension --></valueCodeableConcept>
</extension>

JSON Template

{ // CopyNumberEvent
  // from Element: extension
    "extension" : [ //  sliced by value:url  in the specified order, Open ]
    "url" : "http://hl7.org/fhir/StructureDefinition/observation-geneticsCopyNumberEvent", // R! 
    "valueCodeableConcept" : { CodeableConcept } // C? R! Value of extension
  }

Constraints

• ele-1: All FHIR elements must have a @value or children (xpath: @value|f:*|h:div)
• ext-1: Must have either extensions or value[x], not both (xpath: exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')]))
• ele-1: On Extension.extension: All FHIR elements must have a @value or children (xpath on Extension.extension: @value|f:*|h:div)
• ext-1: On Extension.extension: Must have either extensions or value[x], not both (xpath on Extension.extension: exists(f:extension)!=exists(f:*[starts-with(local-name(.), "value")]))
• ele-1: On Extension.value[x]: All FHIR elements must have a @value or children (xpath on Extension.value[x]: @value|f:*|h:div)