{
  "resourceType" : "CodeSystem",
  "id" : "adverse-event-causality-assess",
  "meta" : {
    "lastUpdated" : "2019-11-01T09:29:23.356+11:00"
  },
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><h2>AdverseEventCausalityAssessment</h2><div><p>Codes for the assessment of whether the entity caused the event.</p>\n</div><p>This code system http://terminology.hl7.org/CodeSystem/adverse-event-causality-assess defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td><td><b>Definition</b></td></tr><tr><td style=\"white-space:nowrap\">Certain<a name=\"adverse-event-causality-assess-Certain\"> </a></td><td>Certain</td><td>i) Event or laboratory test abnormality, with plausible time relationship to drug intake; ii) Cannot be explained by disease or other drugs; iii) Response to withdrawal plausible (pharmacologically, pathologically); iv) Event definitive pharmacologically or phenomenologically (i.e. an objective and specific medical disorder or a recognized pharmacological phenomenon); or v) Re-challenge satisfactory, if necessary.</td></tr><tr><td style=\"white-space:nowrap\">Probably-Likely<a name=\"adverse-event-causality-assess-Probably-Likely\"> </a></td><td>Probably/Likely</td><td>i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Unlikely to be attributed to disease or other drugs; iii) Response to withdrawal clinically reasonable; or iv) Re-challenge not required.</td></tr><tr><td style=\"white-space:nowrap\">Possible<a name=\"adverse-event-causality-assess-Possible\"> </a></td><td>Possible</td><td>i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Could also be explained by disease or other drugs; or iii) Information on drug withdrawal may be lacking or unclear.</td></tr><tr><td style=\"white-space:nowrap\">Unlikely<a name=\"adverse-event-causality-assess-Unlikely\"> </a></td><td>Unlikely</td><td>i) Event or laboratory test abnormality, with a time to drug intake that makes a relationship improbable (but not impossible); or ii) Disease or other drugs provide plausible explanations.</td></tr><tr><td style=\"white-space:nowrap\">Conditional-Classified<a name=\"adverse-event-causality-assess-Conditional-Classified\"> </a></td><td>Conditional/Classified</td><td>i) Event or laboratory test abnormality; ii) More data for proper assessment needed; or iii) Additional data under examination.</td></tr><tr><td style=\"white-space:nowrap\">Unassessable-Unclassifiable<a name=\"adverse-event-causality-assess-Unassessable-Unclassifiable\"> </a></td><td>Unassessable/Unclassifiable</td><td>i) Report suggesting an adverse reaction; ii) Cannot be judged because information is insufficient or contradictory; or iii) Data cannot be supplemented or verified.</td></tr></table></div>"
  },
  "extension" : [{
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
    "valueCode" : "pc"
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
    "valueCode" : "draft"
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
    "valueInteger" : 1
  }],
  "url" : "http://terminology.hl7.org/CodeSystem/adverse-event-causality-assess",
  "identifier" : [{
    "system" : "urn:ietf:rfc:3986",
    "value" : "urn:oid:2.16.840.1.113883.4.642.4.1254"
  }],
  "version" : "4.0.1",
  "name" : "AdverseEventCausalityAssessment",
  "title" : "AdverseEventCausalityAssessment",
  "status" : "draft",
  "experimental" : false,
  "date" : "2019-11-01T09:29:23+11:00",
  "publisher" : "HL7 (FHIR Project)",
  "contact" : [{
    "telecom" : [{
      "system" : "url",
      "value" : "http://hl7.org/fhir"
    },
    {
      "system" : "email",
      "value" : "fhir@lists.hl7.org"
    }]
  }],
  "description" : "Codes for the assessment of whether the entity caused the event.",
  "caseSensitive" : true,
  "valueSet" : "http://hl7.org/fhir/ValueSet/adverse-event-causality-assess",
  "content" : "complete",
  "concept" : [{
    "code" : "Certain",
    "display" : "Certain",
    "definition" : "i) Event or laboratory test abnormality, with plausible time relationship to drug intake; ii) Cannot be explained by disease or other drugs; iii) Response to withdrawal plausible (pharmacologically, pathologically); iv) Event definitive pharmacologically or phenomenologically (i.e. an objective and specific medical disorder or a recognized pharmacological phenomenon); or v) Re-challenge satisfactory, if necessary."
  },
  {
    "code" : "Probably-Likely",
    "display" : "Probably/Likely",
    "definition" : "i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Unlikely to be attributed to disease or other drugs; iii) Response to withdrawal clinically reasonable; or iv) Re-challenge not required."
  },
  {
    "code" : "Possible",
    "display" : "Possible",
    "definition" : "i) Event or laboratory test abnormality, with reasonable time relationship to drug intake; ii) Could also be explained by disease or other drugs; or iii) Information on drug withdrawal may be lacking or unclear."
  },
  {
    "code" : "Unlikely",
    "display" : "Unlikely",
    "definition" : "i) Event or laboratory test abnormality, with a time to drug intake that makes a relationship improbable (but not impossible); or ii) Disease or other drugs provide plausible explanations."
  },
  {
    "code" : "Conditional-Classified",
    "display" : "Conditional/Classified",
    "definition" : "i) Event or laboratory test abnormality; ii) More data for proper assessment needed; or iii) Additional data under examination."
  },
  {
    "code" : "Unassessable-Unclassifiable",
    "display" : "Unassessable/Unclassifiable",
    "definition" : "i) Report suggesting an adverse reaction; ii) Cannot be judged because information is insufficient or contradictory; or iii) Data cannot be supplemented or verified."
  }]
}