Contraindication-example.json

Drug-drug interaction between prescription and medication statement

{
  "resourceType": "Contraindication",
  "id": "ddi",
  "text": {
    "status": "generated",
    "div": "<div>!-- Snipped for Brevity --></div>"
  },
  "category": {
    "coding": [
      {
        "system": "http://hl7.org/fhir/v3/ActCode",
        "code": "DRG",
        "display": "Drug Interaction Alert"
      }
    ]
  },
  "severity": "H",
  "implicated": [
    {
      "reference": "MedicationStatement/tylenol",
      "display": "500 mg Acetaminophen tablet 1/day, PRN since 2010"
    },
    {
      "reference": "MedicationPrescription/warfarin",
      "display": "Warfarin 1 MG TAB prescribed Jan. 5, 2014"
    }
  ],
  "detail": "Risk of internal bleeding.  Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding.",
  "date": "2014-01-05",
  "author": {
    "reference": "Device/dsp"
  },
  "mitigation": [
    {
      "action": {
        "coding": [
          {
            "system": "http://hl7.org/fhir/v3/ActCode",
            "code": "30",
            "display": "Stopped Concurrent Therapy"
          }
        ],
        "text": "Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring"
      },
      "date": "2014-01-05",
      "author": {
        "reference": "Practitioner/example",
        "display": "Dr. Adam Careful"
      }
    }
  ]
}