This page is part of the FHIR Specification v6.0.0-ballot2: Release 6 Ballot (2nd Draft) (see Ballot Notes). The current version is 5.0.0. For a full list of available versions, see the Directory of published versions 
Request for Intravenous Chemotherapy (inpatient order) - Alemtuzumab - completed with multiple dosageInstruction lines
{
"resourceType" : "MedicationRequest",
"id" : "medrx0317",
"contained" : [{
"resourceType" : "Medication",
"id" : "med0303",
"code" : {
"coding" : [{
"system" : "http://www.nlm.nih.gov/research/umls/rxnorm",
"code" : "1594660",
"display" : "alemtuzumab 10 MG/ML [Lemtrada]"
}]
}
}],
"identifier" : [{
"use" : "official",
"system" : "http://www.bmc.nl/portal/prescriptions",
"value" : "12345689"
}],
"status" : "completed",
"intent" : "order",
"medication" : {
"reference" : {
"reference" : "#med0303"
}
},
"subject" : {
"reference" : "Patient/pat1",
"display" : "Donald Duck"
},
"authoredOn" : "2015-01-15",
"requester" : {
"reference" : "Practitioner/f007",
"display" : "Patrick Pump"
},
"reason" : [{
"concept" : {
"coding" : [{
"system" : "http://snomed.info/sct",
"code" : "92814006",
"display" : "Chronic lymphoid leukemia, disease (disorder)"
}]
}
}],
"dosageInstruction" : [{
"sequence" : 1,
"text" : "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk",
"additionalInstruction" : [{
"text" : "Rapidly increase dose until tolerated"
},
{
"text" : "Administer on alternate days"
}],
"timing" : {
"repeat" : {
"duration" : 12,
"durationUnit" : "wk",
"frequency" : 3,
"period" : 1,
"periodUnit" : "wk"
}
},
"route" : {
"coding" : [{
"system" : "http://snomed.info/sct",
"code" : "47625008",
"display" : "Intravenous route"
}]
},
"method" : {
"coding" : [{
"system" : "http://snomed.info/sct",
"code" : "422145002",
"display" : "Inject - dosing instruction imperative (qualifier value)"
}]
},
"doseAndRate" : [{
"type" : {
"coding" : [{
"system" : "http://terminology.hl7.org/CodeSystem/dose-rate-type",
"code" : "ordered",
"display" : "Ordered"
}]
},
"doseQuantity" : {
"value" : 3,
"unit" : "mg",
"system" : "http://unitsofmeasure.org",
"code" : "mg"
}
}]
},
{
"sequence" : 2,
"text" : "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk",
"additionalInstruction" : [{
"text" : "Rapidly increase dose until tolerated"
},
{
"text" : "Administer on alternate days"
}],
"timing" : {
"repeat" : {
"duration" : 12,
"durationUnit" : "wk",
"frequency" : 3,
"period" : 1,
"periodUnit" : "wk"
}
},
"route" : {
"coding" : [{
"system" : "http://snomed.info/sct",
"code" : "47625008",
"display" : "Intravenous route"
}]
},
"method" : {
"coding" : [{
"system" : "http://snomed.info/sct",
"code" : "422145002",
"display" : "Inject - dosing instruction imperative (qualifier value)"
}]
},
"doseAndRate" : [{
"type" : {
"coding" : [{
"system" : "http://terminology.hl7.org/CodeSystem/dose-rate-type",
"code" : "ordered",
"display" : "Ordered"
}]
},
"doseQuantity" : {
"value" : 10,
"unit" : "mg",
"system" : "http://unitsofmeasure.org",
"code" : "mg"
}
}]
},
{
"sequence" : 3,
"text" : "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk",
"additionalInstruction" : [{
"text" : "Rapidly increase dose until tolerated"
},
{
"text" : "Administer on alternate days"
}],
"timing" : {
"repeat" : {
"duration" : 12,
"durationUnit" : "wk",
"frequency" : 3,
"period" : 1,
"periodUnit" : "wk"
}
},
"route" : {
"coding" : [{
"system" : "http://snomed.info/sct",
"code" : "47625008",
"display" : "Intravenous route"
}]
},
"method" : {
"coding" : [{
"system" : "http://snomed.info/sct",
"code" : "422145002",
"display" : "Inject - dosing instruction imperative (qualifier value)"
}]
},
"doseAndRate" : [{
"type" : {
"coding" : [{
"system" : "http://terminology.hl7.org/CodeSystem/dose-rate-type",
"code" : "ordered",
"display" : "Ordered"
}]
},
"doseQuantity" : {
"value" : 30,
"unit" : "mg",
"system" : "http://unitsofmeasure.org",
"code" : "mg"
}
}]
}]
}
Usage note: every effort has been made to ensure that the
examples are correct and useful, but they are not a normative part
of the specification.