Order for as needed (PRN) dosage - Vicodin - completed with dosageInstruction with additionalInstruction (coded) and as needed with reason, dispenseRequest and substitution (id = "medrx0308")

<?xml version="1.0" encoding="UTF-8"?>

<MedicationRequest xmlns="http://hl7.org/fhir">
  <id value="medrx0308"/> 
  <identifier> 
    <use value="official"/> 
    <system value="http://www.bmc.nl/portal/prescriptions"/> 
    <value value="12345689"/> 
  </identifier> 
  <status value="completed"/> 
  <intent value="order"/> 
  <medication> 
    <concept> 
      <coding> 
        <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/> 
        <code value="856907"/> 
        <display value="Vicodin 5/500 (hydrocodone bitartrate / APAP) Oral Tablet"/> 
      </coding> 
    </concept> 
  </medication> 
  <subject> 
    <!--   Linked to the resource patient who needs the medication   -->
    <reference value="Patient/pat1"/> 
    <display value="Donald Duck"/> 
  </subject> 
  <encounter> 
    <!--   Linked to a resource Encounter between patient and practitioner  -->
    <reference value="Encounter/f001"/> 
    <display value="encounter who leads to this prescription"/> 
  </encounter> 
  <authoredOn value="2015-01-15"/> 
  <requester> 
    <reference value="Practitioner/f007"/> 
    <display value="Patrick Pump"/> 
  </requester> 
  <recorder> 
    <reference value="Practitioner/f204"/> 
    <display value="Carla Espinoza"/> 
  </recorder> 
  <dosageInstruction> 
    <sequence value="1"/> 
    <text value="1 tablet every four hours as needed for pain"/> 
    <additionalInstruction> 
      <coding> 
        <system value="http://snomed.info/sct"/> 
        <code value="418914006"/> 
        <display value="Warning. May cause drowsiness. If affected do not drive or operate machinery. Avoid
         alcoholic drink (qualifier value)"/> 
      </coding> 
    </additionalInstruction> 
    <timing> 
      <repeat> 
        <frequency value="1"/> 
        <period value="4"/> 
        <periodUnit value="h"/> 
      </repeat> 
    </timing> 
    <asNeededFor> 
      <coding> 
        <system value="http://snomed.info/sct"/> 
        <code value="203082005"/> 
        <display value="Fibromyalgia (disorder)"/> 
      </coding> 
    </asNeededFor> 
    <route> 
      <coding> 
        <system value="http://snomed.info/sct"/> 
        <code value="26643006"/> 
        <display value="Oral Route"/> 
      </coding> 
    </route> 
    <doseAndRate> 
      <type> 
        <coding> 
          <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/> 
          <code value="ordered"/> 
          <display value="Ordered"/> 
        </coding> 
      </type> 
      <doseQuantity> 
        <value value="1"/> 
        <unit value="TAB"/> 
        <system value="http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm"/> 
        <code value="TAB"/> 
      </doseQuantity> 
    </doseAndRate> 
  </dosageInstruction> 
  <dispenseRequest> 
    <validityPeriod> 
      <start value="2015-01-15"/> 
      <end value="2016-01-15"/> 
    </validityPeriod> 
    <quantity> 
      <value value="30"/> 
      <unit value="TAB"/> 
      <system value="http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm"/> 
      <code value="TAB"/> 
    </quantity> 
    <expectedSupplyDuration> 
      <value value="10"/> 
      <unit value="days"/> 
      <system value="http://unitsofmeasure.org"/> 
      <code value="d"/> 
    </expectedSupplyDuration> 
  </dispenseRequest> 
  <substitution> 
    <allowedBoolean value="false"/> 
    <reason> 
      <coding> 
        <system value="http://terminology.hl7.org/CodeSystem/v3-ActReason"/> 
        <code value="FP"/> 
        <display value="formulary policy"/> 
      </coding> 
    </reason> 
  </substitution> 
</MedicationRequest>