General example of an active ingredient, with presentation, concentration and reference strength

{
  "resourceType" : "Ingredient",
  "id" : "example",
  "status" : "active",
  "role" : {
    "coding" : [{
      "system" : "http://ema.europa.eu/example/ingredientRole",
      "code" : "ActiveBase"
    }]
  },
  "manufacturer" : [{
    "manufacturer" : {
      "reference" : "Organization/example"
    }
  }],
  "substance" : {
    "code" : {
      "concept" : {
        "coding" : [{
          "system" : "http://ema.europa.eu/example/substance",
          "code" : "EQUIXABAN"
        }]
      }
    },
    "strength" : [{
      "presentationRatio" : {
        "numerator" : {
          "value" : 50,
          "unit" : "mg",
          "system" : "http://unitsofmeasure.org",
          "code" : "mg"
        },
        "denominator" : {
          "value" : 1,
          "unit" : "tablet",
          "system" : "http://unitsofmeasure.org",
          "code" : "{tablet}"
        }
      },
      "concentrationRatio" : {
        "numerator" : {
          "value" : 5,
          "unit" : "mg",
          "system" : "http://unitsofmeasure.org",
          "code" : "mg"
        },
        "denominator" : {
          "value" : 1,
          "unit" : "mg",
          "system" : "http://unitsofmeasure.org",
          "code" : "mg"
        }
      },
      "referenceStrength" : [{
        "substance" : {
          "concept" : {
            "coding" : [{
              "system" : "http://ema.europa.eu/example/substance",
              "code" : "EQUIXABAN-SULPHATE"
            }]
          }
        },
        "strengthRatio" : {
          "numerator" : {
            "value" : 5.03,
            "unit" : "mg",
            "system" : "http://unitsofmeasure.org",
            "code" : "mg"
          },
          "denominator" : {
            "value" : 1,
            "unit" : "mg",
            "system" : "http://unitsofmeasure.org",
            "code" : "mg"
          }
        }
      }]
    }]
  }
}