Certainty Rating of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19
{
"resourceType" : "ArtifactAssessment",
"id" : "example-certainty-rating",
"identifier" : [{
"type" : {
"text" : "FEvIR Object Identifier"
},
"system" : "https://fevir.net",
"value" : "27756",
"assigner" : {
"display" : "Computable Publishing LLC"
}
}],
"date" : "2021-11-02T14:48:59.890Z",
"copyright" : "https://creativecommons.org/licenses/by-nc-sa/4.0/",
"artifactReference" : {
"reference" : "Evidence/example-stroke-alteplase-fatalICH",
"type" : "Evidence",
"display" : "Critically appraised summary of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19"
},
"content" : [{
"informationType" : "rating",
"summary" : "serious concerns with risk of bias, inconsistency, and imprecision",
"type" : {
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-type",
"code" : "Overall",
"display" : "Overall certainty"
}]
},
"classifier" : [{
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-rating",
"code" : "very-low",
"display" : "Very low quality"
}]
}],
"author" : {
"display" : "Brian S. Alper"
},
"freeToShare" : true,
"component" : [{
"informationType" : "rating",
"summary" : "risk of bias in both included trials",
"type" : {
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-type",
"code" : "RiskOfBias",
"display" : "Risk of bias"
}]
},
"classifier" : [{
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-rating",
"code" : "serious-concern",
"display" : "serious concern"
}]
}],
"author" : {
"display" : "Brian S. Alper"
}
},
{
"informationType" : "rating",
"summary" : "high degree of heterogeneity (I-squared 80.7%) with confidence intervals of 2 trial effect estimates barely overlapping",
"type" : {
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-type",
"code" : "Inconsistency",
"display" : "Inconsistency"
}]
},
"classifier" : [{
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-rating",
"code" : "serious-concern",
"display" : "serious concern"
}]
}],
"author" : {
"display" : "Brian S. Alper"
}
},
{
"informationType" : "rating",
"type" : {
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-type",
"code" : "Indirectness",
"display" : "Indirectness"
}]
},
"classifier" : [{
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-rating",
"code" : "no-concern",
"display" : "no serious concern"
}]
}],
"author" : {
"display" : "Brian S. Alper"
}
},
{
"informationType" : "rating",
"summary" : "95% confidence interval includes both large effects and no effects",
"type" : {
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-type",
"code" : "Imprecision",
"display" : "Imprecision"
}]
},
"classifier" : [{
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-rating",
"code" : "serious-concern",
"display" : "serious concern"
}]
}],
"author" : {
"display" : "Brian S. Alper"
}
},
{
"informationType" : "rating",
"type" : {
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-type",
"code" : "PublicationBias",
"display" : "Publication bias"
}]
},
"classifier" : [{
"coding" : [{
"system" : "http://hl7.org/fhir/certainty-rating",
"code" : "no-concern",
"display" : "no serious concern"
}]
}],
"author" : {
"display" : "Brian S. Alper"
}
}]
}]
}
Usage note: every effort has been made to ensure that the
examples are correct and useful, but they are not a normative part
of the specification.