Snapshot 3: Connectathon 32 Base
Medication DefinitionThis is Snapshot #3 for FHIR R5, released to support Connectathon 32. For a full list of available versions, see the Directory of published versions.
| Biomedical Research and Regulation Work Group | Maturity Level: N/A | Standards Status: Informative | Compartments: Not linked to any defined compartments |
Raw Turtle (+ also see Turtle/RDF Format Specification)
Example of substancepolymer
@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
# - resource -------------------------------------------------------------------
[a fhir:SubstancePolymer;
fhir:nodeRole fhir:treeRoot;
fhir:Resource.id [ fhir:value "example"]; #
fhir:DomainResource.text [
fhir:Narrative.status [ fhir:value "generated" ];
fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: SubstancePolymer</b><a name=\"example\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource SubstancePolymer "example" </p></div></div>"
]] . # numberOfMoieties value="2"/>
<identifier>
<system value="http://substanceidOID"/>
<value value="POYFG4531Y (Artificial ID)"/>
</identifier>
<substanceType>
<coding>
<system value="http://substancetypeOID"/>
<code value="Chemical"/>
</coding>
</substanceType>
<moiety>
<moietyRole>
<coding>
<system value="http://moietyroleOID"/>
<code value="SaltMolecule"/>
</coding>
</moietyRole>
<moietyId>
<system value="http://moietyidOID"/>
<value value="HJFGTE8954 (Artificial ID); [QTT17582CB (UNII)]"/>
</moietyId>
<moietyName value="Hydrochloric acid"/>
<stereochemistry>
<coding>
<system value="http://stereochemistryOID"/>
<code value="Achiral"/>
</coding>
</stereochemistry>
<opticalActivity>
<coding>
<system value="http://opticalactivityOID"/>
<code value="N/A"/>
</coding>
</opticalActivity>
<molecularFormula value="HCl"/>
<amount>
<amountType>
<coding>
<system value="http://amounttypeOID"/>
<code value="MoleRatiotoParent"/>
</coding>
</amountType>
<average>
<value value="1"/>
<unit value="1"/>
</average>
<nonNumericValue value="Mole Ratio to Ponatinib"/>
</amount>
</moiety>
<moiety>
<moietyRole>
<coding>
<system value="http://moietyroleOID"/>
<code value="Parentsubstance"/>
</coding>
</moietyRole>
<moietyId>
<system value="http://moietyidOID"/>
<value value="PONG785632B (Artificial ID); [QTT17582CB (UNII)]"/>
</moietyId>
<moietyName value="Ponatinib"/>
<stereochemistry>
<coding>
<system value="http://stereochemistryOID"/>
<code value="Achiral"/>
</coding>
</stereochemistry>
<opticalActivity>
<coding>
<system value="http://opticalactivityOID"/>
<code value="N/A"/>
</coding>
</opticalActivity>
<molecularFormula value="C29H27F3N6O"/>
<amount>
<amountType>
<coding>
<system value="http://amounttypeOID"/>
<code value="MoleRatiotoAcid"/>
</coding>
</amountType>
<average>
<value value="1"/>
<unit value="1"/>
</average>
<nonNumericValue value="Mol Ratio Ponatinib/ Ponatinib hydrochloride (1:1)"/>
</amount>
</moiety>
<referenceInformation>
<substanceClassification>
<domain>
<coding>
<system value="http://domainOID"/>
<code value="HumanPharmaceutical"/>
</coding>
</domain>
<substanceClassificationCode value="L01XE24"/>
<substanceClassificationType value="Ponatinib"/>
<referenceSource>
<publicDomain value="true"/>
<referenceSourceType>
<coding>
<system value="http://referencesourcetypeOID"/>
<code value="WHOCollaboratingCentreforDrugStatisticsmethodology(WHOCC)"/>
</coding>
</referenceSourceType>
<referenceSourceClass>
<coding>
<system value="http://referencesourceclassOID"/>
<code value="Web"/>
</coding>
</referenceSourceClass>
<referenceSourceCitation value="http://www.whocc.no/atc_ddd_index/?code=L01XE24 "/>
</referenceSource>
</substanceClassification>
<substanceRelationship>
<relatedSubstanceId>
<system value="http://relatedsubstanceidOID"/>
<value value="GHF26754YQ (Artificial ID), [4340891KFS (UNII)]"/>
</relatedSubstanceId>
<relatedSubstanceName value="Ponatinib"/>
<relationship>
<coding>
<system value="http://relationshipOID"/>
<code value="Parentsubstancetosalt"/>
</coding>
</relationship>
<relationshipType>
<coding>
<system value="http://relationshiptypeOID"/>
<code value="Ionic"/>
</coding>
</relationshipType>
<isDefining value="true"/>
<amount>
<amountType>
<coding>
<system value="http://amounttypeOID"/>
<code value="Weightpercenttosalt"/>
</coding>
</amountType>
<average>
<value value="93.6"/>
<unit value="1"/>
</average>
<unit>
<coding>
<system value="http://unitOID"/>
<code value="Weightpercent"/>
</coding>
</unit>
<nonNumericValue value="Equivalent factor: 0.936"/>
</amount>
</substanceRelationship>
</referenceInformation>
<referenceSource>
<publicDomain value="false"/>
<referenceSourceType>
<coding>
<system value="http://referencesourcetypeOID"/>
<code value="MarketingAuthorisationApplication"/>
</coding>
</referenceSourceType>
<referenceSourceClass>
<coding>
<system value="http://referencesourceclassOID"/>
<code value="Regulatorysubmission"/>
</coding>
</referenceSourceClass>
<referenceSourceId value="33333 (Artificial ID)"/>
<referenceSourceDocument>
<document>
<contentType value="text/plain"/>
<data value="U3lteXggICAwNjA5MTQyMjExMkQgMSAgIDEuMDAwMDAgICAgIDAuMDAwMDAgICAgIDAgXG4gNDAgNDMgIDAgICAgIDAgIDAgICAgICAgICAgICA5OTkgVjIwMDBcbiAgIC0yLjIzNDAgICAtMC4xNjYxICAgIDAuMDAwMCBOICAgMCAgMCAgMCAgMCAgMCAgMCAgICAgICAgICAgMCAgMCAgMA=="/>
</document>
<referenceSourceDocumentType>
<coding>
<system value="http://referencesourcedocumenttypeOID"/>
<code value="Textfile"/>
</coding>
</referenceSourceDocumentType>
</referenceSourceDocument>
</referenceSource>
<structure>
<stereochemistry>
<coding>
<system value="http://stereochemistryOID"/>
<code value="Achiral"/>
</coding>
</stereochemistry>
<opticalActivity>
<coding>
<system value="http://opticalactivityOID"/>
<code value="N/A"/>
</coding>
</opticalActivity>
<molecularFormula value="C29H28F3ClN6O"/>
<molecularFormulaByMoiety value="C29H27F3N6O.HCl"/>
<molecularWeight>
<molecularWeightMethod>
<coding>
<system value="http://molecularweightmethodOID"/>
<code value="Calculated"/>
</coding>
</molecularWeightMethod>
<molecularWeightType>
<coding>
<system value="http://molecularweighttypeOID"/>
<code value="Numberaverage"/>
</coding>
</molecularWeightType>
<amount>
<amountType>
<coding>
<system value="http://amounttypeOID"/>
<code value="Exact"/>
</coding>
</amountType>
<average>
<value value="569.02"/>
<unit value="1"/>
</average>
<unit>
<coding>
<system value="http://unitOID"/>
<code value="g/mol"/>
</coding>
</unit>
</amount>
</molecularWeight>
<referenceSource>
<publicDomain value="true"/>
<referenceSourceType>
<coding>
<system value="http://referencesourcetypeOID"/>
<code value="ChemIDplus"/>
</coding>
</referenceSourceType>
<referenceSourceClass>
<coding>
<system value="http://referencesourceclassOID"/>
<code value="PublicDatabase"/>
</coding>
</referenceSourceClass>
<referenceSourceCitation value="http://chem.sis.nlm.nih.gov/chemidplus/unii/96R6PU3D8J "/>
</referenceSource>
<structuralRepresentation>
<type>
<coding>
<system value="http://structuralrepresentationtypeOID"/>
<code value="Full"/>
</coding>
</type>
<representation value="Figure B.40"/>
</structuralRepresentation>
<structuralRepresentation>
<type>
<coding>
<system value="http://structuralrepresentationtypeOID"/>
<code value="InChI"/>
</coding>
</type>
<representation value="InChI=1S/C29H27F3N6O.ClH/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37;/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39);1H"/>
</structuralRepresentation>
<structuralRepresentation>
<type>
<coding>
<system value="http://structuralrepresentationtypeOID"/>
<code value="SMILES"/>
</coding>
</type>
<representation value="Cc1ccc(cc1C#Cc2cnc3n2nccc3)C(=O)Nc4ccc(c(c4)C(F)(F)F)CN5CCN(CC5)C.Cl"/>
</structuralRepresentation>
<structuralRepresentation>
<type>
<coding>
<system value="http://structuralrepresentationtypeOID"/>
<code value="MOL"/>
</coding>
</type>
<attachment>
<contentType value="text/plain"/>
<data value="U3lteXggICAwNjA5MTQyMjExMkQgMSAgIDEuMDAwMDAgICAgIDAuMDAwMDAgICAgIDAgXG4gNDAgNDMgIDAgICAgIDAgIDAgICAgICAgICAgICA5OTkgVjIwMDBcbiAgIC0yLjIzNDAgICAtMC4xNjYxICAgIDAuMDAwMCBOICAgMCAgMCAgMCAgMCAgMCAgMCAgICAgICAgICAgMCAgMCAgMA=="/>
</attachment>
</structuralRepresentation>
</structure>
<substanceCode>
<code value="1114544-31-8"/>
<codeSystemStatus>
<coding>
<system value="http://1.1.149"/>
<code value="Active"/>
</coding>
</codeSystemStatus>
</substanceCode>
<substanceCode>
<code value="96R6PU3D8J"/>
<codeSystemStatus>
<coding>
<system value="http://1.1.150"/>
<code value="Active"/>
</coding>
</codeSystemStatus>
</substanceCode>
<substanceName>
<substanceName value="Ponatinib hydrochloride"/>
<substanceNameType>
<coding>
<system value="http://substancenametypeOID"/>
<code value="Official"/>
</coding>
</substanceNameType>
<language>
<coding>
<system value="http://languageOID"/>
<code value="en"/>
</coding>
</language>
<substanceNameDomain>
<coding>
<system value="http://substancenamedomainOID"/>
<code value="Drug"/>
</coding>
</substanceNameDomain>
<jurisdiction>
<coding>
<system value="http://jurisdictionOID"/>
<code value="EU,US"/>
</coding>
</jurisdiction>
<officialName>
<officialNameType>
<coding>
<system value="http://officialnametypeOID"/>
<code value="USAN"/>
</coding>
</officialNameType>
<officialNameStatus>
<coding>
<system value="http://officialnamestatusOID"/>
<code value="Current"/>
</coding>
</officialNameStatus>
</officialName>
<referenceSource>
<publicDomain value="true"/>
<referenceSourceType>
<coding>
<system value="http://referencesourcetypeOID"/>
<code value="Martindale"/>
</coding>
</referenceSourceType>
<referenceSourceClass>
<coding>
<system value="http://referencesourceclassOID"/>
<code value="Officialnamesource"/>
</coding>
</referenceSourceClass>
<referenceSourceCitation value="Martindale The complete drug reference"/>
<referenceSourceUrl value="https://www.medicinescomplete.com/mc/martindale/current/ms-28485-s.htm?q=Ponatinib%20hydrochloride&t=search&ss=text&tot=12&p=1#_hit"/>
<referenceSourceDocument>
<publicDomain value="true"/>
<referenceSourceDocumentType>
<coding>
<system value="http://referencesourcedocumenttypeOID"/>
<code value="Journalarticle"/>
</coding>
</referenceSourceDocumentType>
</referenceSourceDocument>
</referenceSource>
</substanceName>
<substanceName>
<substanceName value="3-(2-(Imidazo(1,2-b)pyridazin-3-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide monohydrochloride"/>
<substanceNameType>
<coding>
<system value="http://substancenametypeOID"/>
<code value="Systematic"/>
</coding>
</substanceNameType>
<language>
<coding>
<system value="http://languageOID"/>
<code value="en"/>
</coding>
</language>
<referenceSource>
<publicDomain value="true"/>
<referenceSourceType>
<coding>
<system value="http://referencesourcetypeOID"/>
<code value="ChemIDplus"/>
</coding>
</referenceSourceType>
<referenceSourceClass>
<coding>
<system value="http://referencesourceclassOID"/>
<code value="PublicDatabase"/>
</coding>
</referenceSourceClass>
<referenceSourceCitation value="http://chem.sis.nlm.nih.gov/chemidplus/unii/96R6PU3D8J "/>
</referenceSource>
</substanceName>
<substanceName>
<substanceName value="Benzamide, 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-,hydrochloride (1:1)"/>
<substanceNameType>
<coding>
<system value="http://substancenametypeOID"/>
<code value="OtherName"/>
</coding>
</substanceNameType>
<language>
<coding>
<system value="http://languageOID"/>
<code value="en"/>
</coding>
</language>
<referenceSource>
<publicDomain value="true"/>
<referenceSourceType>
<coding>
<system value="http://referencesourcetypeOID"/>
<code value="CAS"/>
</coding>
</referenceSourceType>
<referenceSourceClass>
<coding>
<system value="http://referencesourceclassOID"/>
<code value="Othernamesource"/>
</coding>
</referenceSourceClass>
<referenceSourceCitation value="CAS Registry Name"/>
</referenceSource>
</substanceName>
<substanceName>
<substanceName value="XYWZ123"/>
<substanceNameType>
<coding>
<system value="http://substancenametypeOID"/>
<code value="CompanyCode"/>
</coding>
</substanceNameType>
<language>
<coding>
<system value="http://languageOID"/>
<code value="en"/>
</coding>
</language>
<referenceSource>
<publicDomain value="false"/>
<referenceSourceType>
<coding>
<system value="http://referencesourcetypeOID"/>
<code value="MarketingAuthorisationApplication"/>
</coding>
</referenceSourceType>
<referenceSourceClass>
<coding>
<system value="http://referencesourceclassOID"/>
<code value="Regulatorysubmission"/>
</coding>
</referenceSourceClass>
<referenceSourceId value="CBG345267C (Artificial ID)"/>
</referenceSource>
</substanceName
# - ontology header ------------------------------------------------------------
[a owl:Ontology;
owl:imports fhir:fhir.ttl] .
# -------------------------------------------------------------------------------------
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.
FHIR ®© HL7.org 2011+. FHIR R5 Ballot hl7.fhir.core#5.0.0-snapshot3 generated on Wed, Dec 14, 2022 07:17+1100.
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