Request referencing Medication Resource for Eye Drops - Timoptic - active - with link to encounter, dispenseRequest and substitution flag

{
  "resourceType" : "MedicationRequest",
  "id" : "medrx0330",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: MedicationRequest</b><a name=\"medrx0330\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationRequest &quot;medrx0330&quot; </p></div><p><b>identifier</b>: id: 12345689 (use: OFFICIAL)</p><p><b>status</b>: active</p><p><b>intent</b>: order</p><h3>Medications</h3><table class=\"grid\"><tr><td>-</td><td><b>Reference</b></td></tr><tr><td>*</td><td><span title=\"  Linked to a RESOURCE Medication  \"><a name=\"med0305\"> </a></span><blockquote><p/><p><a name=\"med0305\"> </a></p><p><b>code</b>: Timoptic 5mg/ml solution <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/4.0.0/CodeSystem-v3-ndc.html\">National drug codes</a>#24208-813-10)</span></p></blockquote></td></tr></table><p><b>subject</b>: <a href=\"patient-example-a.html\">Patient/pat1: Donald Duck</a> &quot;Donald DUCK&quot;</p><p><b>encounter</b>: <a href=\"encounter-example-f002-lung.html\">Encounter/f002: encounter who leads to this prescription</a></p><p><b>authoredOn</b>: 2015-01-15</p><p><b>requester</b>: <a href=\"practitioner-example-f007-sh.html\">Practitioner/f007: Patrick Pump</a> &quot;Simone HEPS&quot;</p><blockquote><p><b>dose</b></p><blockquote><p><b>dosageInstruction</b></p><p><b>sequence</b>: 1</p><p><b>text</b>: Instil one drop in each eye twice daily</p><p><b>timing</b>: 2 per 1 days</p><p><b>route</b>: Ophthalmic route (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#54485002)</span></p><p><b>method</b>: Instill - dosing instruction imperative (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#421538008)</span></p></blockquote></blockquote><blockquote><p><b>dispenseRequest</b></p><p><b>validityPeriod</b>: 2015-01-15 --&gt; 2016-01-15</p><p><b>numberOfRepeatsAllowed</b>: 1</p><p><b>quantity</b>: 10 mL<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code mL = 'mL')</span></p><h3>ExpectedSupplyDurations</h3><table class=\"grid\"><tr><td>-</td><td><b>Value</b></td><td><b>Unit</b></td><td><b>System</b></td><td><b>Code</b></td></tr><tr><td>*</td><td>30</td><td>days</td><td><a href=\"http://terminology.hl7.org/4.0.0/CodeSystem-v3-ucum.html\">Unified Code for Units of Measure (UCUM)</a></td><td>d</td></tr></table></blockquote><h3>Substitutions</h3><table class=\"grid\"><tr><td>-</td><td><b>Allowed[x]</b></td><td><b>Reason</b></td></tr><tr><td>*</td><td>false</td><td>formulary policy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/4.0.0/CodeSystem-v3-ActReason.html\">ActReason</a>#FP)</span></td></tr></table></div>"
  },
  "contained" : [{
    "resourceType" : "Medication",
    "id" : "med0305",
    "code" : {
      "coding" : [{
        "system" : "http://hl7.org/fhir/sid/ndc",
        "code" : "24208-813-10",
        "display" : "Timoptic 5mg/ml solution"
      }]
    }
  }],
  "identifier" : [{
    "use" : "official",
    "system" : "http://www.bmc.nl/portal/prescriptions",
    "value" : "12345689"
  }],
  "status" : "active",
  "intent" : "order",
  "medication" : {
    "reference" : {
      "reference" : "#med0305"
    }
  },
  "subject" : {
    "reference" : "Patient/pat1",
    "display" : "Donald Duck"
  },
  "encounter" : {
    "reference" : "Encounter/f002",
    "display" : "encounter who leads to this prescription"
  },
  "authoredOn" : "2015-01-15",
  "requester" : {
    "reference" : "Practitioner/f007",
    "display" : "Patrick Pump"
  },
  "dose" : {
    "dosageInstruction" : [{
      "sequence" : 1,
      "text" : "Instil one drop in each eye twice daily",
      "timing" : {
        "repeat" : {
          "frequency" : 2,
          "period" : 1,
          "periodUnit" : "d"
        }
      },
      "route" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "54485002",
          "display" : "Ophthalmic route (qualifier value)"
        }]
      },
      "method" : {
        "coding" : [{
          "system" : "http://snomed.info/sct",
          "code" : "421538008",
          "display" : "Instill - dosing instruction imperative (qualifier value)"
        }]
      },
      "doseAndRate" : [{
        "type" : {
          "coding" : [{
            "system" : "http://terminology.hl7.org/CodeSystem/dose-rate-type",
            "code" : "ordered",
            "display" : "Ordered"
          }]
        },
        "doseQuantity" : {
          "value" : 1,
          "unit" : "OPDROP",
          "system" : "http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm",
          "code" : "OPDROP"
        }
      }]
    }]
  },
  "dispenseRequest" : {
    "validityPeriod" : {
      "start" : "2015-01-15",
      "end" : "2016-01-15"
    },
    "numberOfRepeatsAllowed" : 1,
    "quantity" : {
      "value" : 10,
      "unit" : "mL",
      "system" : "http://unitsofmeasure.org",
      "code" : "mL"
    },
    "expectedSupplyDuration" : {
      "value" : 30,
      "unit" : "days",
      "system" : "http://unitsofmeasure.org",
      "code" : "d"
    }
  },
  "substitution" : {
    "allowedBoolean" : false,
    "reason" : {
      "coding" : [{
        "system" : "http://terminology.hl7.org/CodeSystem/v3-ActReason",
        "code" : "FP",
        "display" : "formulary policy"
      }]
    }
  }
}