Clinical ReasoningThis is Snapshot #3 for FHIR R5, released to support Connectathon 32. For a full list of available versions, see the Directory of published versions.
| Clinical Decision Support Work Group | Maturity Level: N/A | Standards Status: Informative | Compartments: Not linked to any defined compartments |
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Certainty Rating of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19
@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
# - resource -------------------------------------------------------------------
[a fhir:ArtifactAssessment;
fhir:nodeRole fhir:treeRoot;
fhir:Resource.id [ fhir:value "example-certainty-rating"]; #
fhir:DomainResource.text [
fhir:Narrative.status [ fhir:value "generated" ];
fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ArtifactAssessment</b><a name=\"example-certainty-rating\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ArtifactAssessment "example-certainty-rating" </p></div><p><b>identifier</b>: FEvIR Object Identifier: 27756</p><p><b>date</b>: 2021-11-02T14:48:59.89Z</p><p><b>copyright</b>: https://creativecommons.org/licenses/by-nc-sa/4.0/</p><p><b>artifact</b>: <a href=\"broken-link.html\">Evidence/18812: Critically appraised summary of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19</a></p><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>summary</b>: serious concerns with risk of bias, inconsistency, and imprecision</p><p><b>type</b>: Overall certainty <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#Overall)</span></p><p><b>classifier</b>: Very low quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#very-low)</span></p><p><b>author</b>: <span>: Brian S. Alper</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td>-</td><td><b>InformationType</b></td><td><b>Summary</b></td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>Author</b></td></tr><tr><td>*</td><td>rating</td><td>risk of bias in both included trials</td><td>Risk of bias <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#RiskOfBias)</span></td><td>serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#serious-concern)</span></td><td><span>: Brian S. Alper</span></td></tr><tr><td>*</td><td>rating</td><td>high degree of heterogeneity (I-squared 80.7%) with confidence intervals of 2 trial effect estimates barely overlapping</td><td>Inconsistency <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#Inconsistency)</span></td><td>serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#serious-concern)</span></td><td><span>: Brian S. Alper</span></td></tr><tr><td>*</td><td>rating</td><td> </td><td>Indirectness <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#Indirectness)</span></td><td>no serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#no-concern)</span></td><td><span>: Brian S. Alper</span></td></tr><tr><td>*</td><td>rating</td><td>95% confidence interval includes both large effects and no effects</td><td>Imprecision <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#Imprecision)</span></td><td>serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#serious-concern)</span></td><td><span>: Brian S. Alper</span></td></tr><tr><td>*</td><td>rating</td><td> </td><td>Publication bias <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#PublicationBias)</span></td><td>no serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#no-concern)</span></td><td><span>: Brian S. Alper</span></td></tr></table></blockquote></div>"
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fhir:CodeableConcept.text [ fhir:value "FEvIR Object Identifier" ]
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fhir:Identifier.system [ fhir:value "https://fevir.net" ];
fhir:Identifier.value [ fhir:value "27756" ];
fhir:Identifier.assigner [
fhir:Reference.display [ fhir:value "Computable Publishing LLC" ]
]
]; #
fhir:ArtifactAssessment.date [ fhir:value "2021-11-02T14:48:59.890Z"^^xsd:dateTime]; #
fhir:ArtifactAssessment.copyright [ fhir:value "https://creativecommons.org/licenses/by-nc-sa/4.0/"]; #
fhir:ArtifactAssessment.artifactReference [
fhir:Reference.reference [ fhir:value "Evidence/18812" ];
fhir:Reference.type [ fhir:value "Evidence" ];
fhir:Reference.display [ fhir:value "Critically appraised summary of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19" ]
]; #
fhir:ArtifactAssessment.content [
fhir:index 0;
fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ];
fhir:ArtifactAssessment.content.summary [ fhir:value "serious concerns with risk of bias, inconsistency, and imprecision" ];
fhir:ArtifactAssessment.content.type [
fhir:CodeableConcept.coding [
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fhir:Coding.code [ fhir:value "Overall" ];
fhir:Coding.display [ fhir:value "Overall certainty" ]
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fhir:CodeableConcept.coding [
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fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-rating" ];
fhir:Coding.code [ fhir:value "very-low" ];
fhir:Coding.display [ fhir:value "Very low quality" ]
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fhir:ArtifactAssessment.content.author [
fhir:Reference.display [ fhir:value "Brian S. Alper" ]
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fhir:ArtifactAssessment.content.freeToShare [ fhir:value "true"^^xsd:boolean ];
fhir:ArtifactAssessment.content.component [
fhir:index 0;
fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ];
fhir:ArtifactAssessment.content.summary [ fhir:value "risk of bias in both included trials" ];
fhir:ArtifactAssessment.content.type [
fhir:CodeableConcept.coding [
fhir:index 0;
fhir:Coding.system [ fhir:value "http://hl7.org/fhir/certainty-type" ];
fhir:Coding.code [ fhir:value "RiskOfBias" ];
fhir:Coding.display [ fhir:value "Risk of bias" ]
]
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fhir:ArtifactAssessment.content.classifier [
fhir:index 0;
fhir:CodeableConcept.coding [
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fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-rating" ];
fhir:Coding.code [ fhir:value "serious-concern" ];
fhir:Coding.display [ fhir:value "serious concern" ]
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fhir:ArtifactAssessment.content.author [
fhir:Reference.display [ fhir:value "Brian S. Alper" ]
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fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ];
fhir:ArtifactAssessment.content.summary [ fhir:value "high degree of heterogeneity (I-squared 80.7%) with confidence intervals of 2 trial effect estimates barely overlapping" ];
fhir:ArtifactAssessment.content.type [
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fhir:index 0;
fhir:Coding.system [ fhir:value "http://hl7.org/fhir/certainty-type" ];
fhir:Coding.code [ fhir:value "Inconsistency" ];
fhir:Coding.display [ fhir:value "Inconsistency" ]
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fhir:ArtifactAssessment.content.classifier [
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fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-rating" ];
fhir:Coding.code [ fhir:value "serious-concern" ];
fhir:Coding.display [ fhir:value "serious concern" ]
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fhir:ArtifactAssessment.content.author [
fhir:Reference.display [ fhir:value "Brian S. Alper" ]
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fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ];
fhir:ArtifactAssessment.content.type [
fhir:CodeableConcept.coding [
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fhir:Coding.system [ fhir:value "http://hl7.org/fhir/certainty-type" ];
fhir:Coding.code [ fhir:value "Indirectness" ];
fhir:Coding.display [ fhir:value "Indirectness" ]
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fhir:ArtifactAssessment.content.classifier [
fhir:index 0;
fhir:CodeableConcept.coding [
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fhir:Coding.display [ fhir:value "no serious concern" ]
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fhir:ArtifactAssessment.content.author [
fhir:Reference.display [ fhir:value "Brian S. Alper" ]
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fhir:index 3;
fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ];
fhir:ArtifactAssessment.content.summary [ fhir:value "95% confidence interval includes both large effects and no effects" ];
fhir:ArtifactAssessment.content.type [
fhir:CodeableConcept.coding [
fhir:index 0;
fhir:Coding.system [ fhir:value "http://hl7.org/fhir/certainty-type" ];
fhir:Coding.code [ fhir:value "Imprecision" ];
fhir:Coding.display [ fhir:value "Imprecision" ]
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fhir:ArtifactAssessment.content.classifier [
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fhir:Coding.display [ fhir:value "serious concern" ]
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fhir:ArtifactAssessment.content.author [
fhir:Reference.display [ fhir:value "Brian S. Alper" ]
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fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ];
fhir:ArtifactAssessment.content.type [
fhir:CodeableConcept.coding [
fhir:index 0;
fhir:Coding.system [ fhir:value "http://hl7.org/fhir/certainty-type" ];
fhir:Coding.code [ fhir:value "PublicationBias" ];
fhir:Coding.display [ fhir:value "Publication bias" ]
]
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fhir:ArtifactAssessment.content.classifier [
fhir:index 0;
fhir:CodeableConcept.coding [
fhir:index 0;
fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-rating" ];
fhir:Coding.code [ fhir:value "no-concern" ];
fhir:Coding.display [ fhir:value "no serious concern" ]
]
];
fhir:ArtifactAssessment.content.author [
fhir:Reference.display [ fhir:value "Brian S. Alper" ]
]
]
]] . #
# - ontology header ------------------------------------------------------------
[a owl:Ontology;
owl:imports fhir:fhir.ttl] .
# -------------------------------------------------------------------------------------
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.
FHIR ®© HL7.org 2011+. FHIR R5 Ballot hl7.fhir.core#5.0.0-snapshot3 generated on Wed, Dec 14, 2022 07:16+1100.
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