This page is part of the FHIR Specification (v5.0.0-snapshot1: Release 5 Snapshot #1). The current version which supercedes this version is 5.0.0. For a full list of available versions, see the Directory of published versions
. Page versions: R5 R4B R4 R3
| Clinical Decision Support Work Group | Maturity Level: N/A | Standards Status: Informative | Compartments: Device, Patient, Practitioner |
Raw Turtle (+ also see Turtle/RDF Format Specification)
Drug-drug interaction between prescription and medication statement
@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
# - resource -------------------------------------------------------------------
<http://hl7.org/fhir/DetectedIssue/ddi> a fhir:DetectedIssue;
fhir:nodeRole fhir:treeRoot;
fhir:Resource.id [ fhir:value "ddi"];
fhir:DomainResource.text [
fhir:Narrative.status [ fhir:value "generated" ];
fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n <p><b>Severity: High</b> - Risk of internal bleeding</p>\n <p>Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding.</p>\n <ul>\n <li><a href=\"MedicationUsage/tylenol\">500 mg Acetaminophen tablet 1/day, PRN since 2010</a></li>\n <li><a href=\"MedicationRequest/warfarin\">Warfarin 1 MG TAB prescribed Jan. 5, 2014</a></li>\n </ul>\n <p>Mitigation: Jan 5, 2014 by Dr. Adam Careful: </p>\n <p>Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring</p>\n </div>"
];
fhir:DetectedIssue.status [ fhir:value "final"];
fhir:DetectedIssue.code [
fhir:CodeableConcept.coding [
fhir:index 0;
fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-ActCode" ];
fhir:Coding.code [ fhir:value "DRG" ];
fhir:Coding.display [ fhir:value "Drug Interaction Alert" ]
]
];
fhir:DetectedIssue.severity [ fhir:value "high"];
fhir:DetectedIssue.identifiedDateTime [ fhir:value "2014-01-05"^^xsd:date];
fhir:DetectedIssue.author [
fhir:link <http://hl7.org/fhir/Device/example>;
fhir:Reference.reference [ fhir:value "Device/example" ]
];
fhir:DetectedIssue.implicated [
fhir:index 0;
fhir:link <http://hl7.org/fhir/MedicationUsage/example001>;
fhir:Reference.reference [ fhir:value "MedicationUsage/example001" ];
fhir:Reference.display [ fhir:value "500 mg Acetaminophen tablet 1/day, PRN since 2010" ]
], [
fhir:index 1;
fhir:link <http://hl7.org/fhir/MedicationRequest/medrx0331>;
fhir:Reference.reference [ fhir:value "MedicationRequest/medrx0331" ];
fhir:Reference.display [ fhir:value "Warfarin 1 MG TAB prescribed Jan. 15, 2015" ]
];
fhir:DetectedIssue.detail [ fhir:value "Risk of internal bleeding. Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding."];
fhir:DetectedIssue.mitigation [
fhir:index 0;
fhir:DetectedIssue.mitigation.action [
fhir:CodeableConcept.coding [
fhir:index 0;
fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/v3-ActCode" ];
fhir:Coding.code [ fhir:value "13" ];
fhir:Coding.display [ fhir:value "Stopped Concurrent Therapy" ]
];
fhir:CodeableConcept.text [ fhir:value "Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring" ]
];
fhir:DetectedIssue.mitigation.date [ fhir:value "2014-01-05"^^xsd:date ];
fhir:DetectedIssue.mitigation.author [
fhir:link <http://hl7.org/fhir/Practitioner/example>;
fhir:Reference.reference [ fhir:value "Practitioner/example" ];
fhir:Reference.display [ fhir:value "Dr. Adam Careful" ]
]
] .
<http://hl7.org/fhir/Device/example> a fhir:Device .
<http://hl7.org/fhir/MedicationUsage/example001> a fhir:MedicationUsage .
<http://hl7.org/fhir/MedicationRequest/medrx0331> a fhir:MedicationRequest .
<http://hl7.org/fhir/Practitioner/example> a fhir:Practitioner .
# - ontology header ------------------------------------------------------------
<http://hl7.org/fhir/DetectedIssue/ddi.ttl> a owl:Ontology;
owl:imports fhir:fhir.ttl;
owl:versionIRI <http://build.fhir.org/DetectedIssue/ddi.ttl> .
# -------------------------------------------------------------------------------------
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.