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Clinical Decision Support Work Group | Maturity Level: N/A | Standards Status: Informative | Compartments: Not linked to any defined compartments |
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Chemotherapy Regimen
@prefix fhir: <http://hl7.org/fhir/> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- [a fhir:PlanDefinition; fhir:nodeRole fhir:treeRoot; fhir:Resource.id [ fhir:value "KDN5"]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "additional" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n <table style=\"width: 100%;\">\n <tr>\n <td>\n <!-- link to NCCN image -->\n <div style=\"width: 200px; height: 100px; vertical-align: top;\">National Comprehensive Cancer Network</div>\n </td>\n <td>\n <h3>Chemotherapy Order Template</h3>\n <h1>Kidney Cancer</h1>\n <h2>Gemcitabine/CARBOplatin</h2>\n </td>\n <td style=\"text-align: right; vertical-align: top;\">KDN5</td>\n </tr>\n </table>\n <table style=\"width: 100%; border-top: 1px solid; border-bottom: 1px solid;\">\n <tr>\n <td style=\"width: 33%; border-right: 1px solid; vertical-align: top\">\n <h4>INDICATION:</h4>\n <p>Metastatic or Relapsed – Collecting Duct/Medullary Subtypes</p>\n </td>\n <td style=\"width: 34%; border-right: 1px solid; vertical-align: top\">\n <h4>REFERENCES:</h4>\n <ol>\n <li><a href=\"http://www.example.org/professionals/physician_gls/PDF/kidney.pdf\">NCCN Guidelines® for Kidney Cancer. V.3.2015.</a></li>\n <li><a href=\"http://www.ncbi.nlm.nih.gov/pubmed?term=%22The+Journal+of+urology%22%5BJour%5D+AND+1698%5Bpage%5D+AND+2007%5Bpdat%5D+AND+Oudard+S%5Bauthor%5D\">Oudard S, et al. <em>J Urol</em>. 2007;177(5):1698-702.</a><sup>\n <a href=\"http://www.example.org/OrderTemplates/PDF/appendix_E.pdf\">a</a></sup>\n </li>\n </ol>\n </td>\n <td style=\"width: 33%; vertical-align: top\">\n <h4>NCCN SUPPORTIVE CARE:</h4>\n <ol>\n <li>\n <i>Emetic Risk:</i>\n <table>\n <tr>\n <td>Day 1</td>\n <td>Moderate</td>\n </tr>\n <tr>\n <td>Day 8</td>\n <td>Low</td>\n </tr>\n </table>\n </li>\n <li>\n <i>Fever Neutropenia Risk:</i><br/>\n Refer to <a href=\"http://www.example.org/professionals/physician_gls/PDF/myeloid_growth.pdf\">NCCN Guidelines for Myeloid Growth Factors. V.2.2014</a>\n </li>\n </ol>\n </td>\n </tr>\n </table>\n <!-- same as the regimen section of the Composition resource only this version is without the style guide notes -->\n <h4>CHEMOTHERAPY REGIMEN</h4>\n <p>\n <i>21-day cycle for 6 cycles</i>\n </p>\n <ul>\n <li>Gemcitabine 1250 mg/m<sup>2</sup> IV over 30 minutes on Days 1 and 8</li>\n <li>CARBOplatin AUC 5 IV over 30 minutes on Day 1</li>\n </ul>\n </div>" ]; fhir:DomainResource.contained [ a fhir:ActivityDefinition; fhir:index 0; fhir:Resource.id [ fhir:value "1111" ]; fhir:ActivityDefinition.status [ fhir:value "draft" ]; fhir:ActivityDefinition.productCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ]; fhir:Coding.code [ fhir:value "12574" ]; fhir:Coding.display [ fhir:value "gemcitabine" ] ]; fhir:CodeableConcept.text [ fhir:value "gemcitabine" ] ]; fhir:ActivityDefinition.dosage [ fhir:index 0; fhir:Dosage.text [ fhir:value "1250 mg/m² IV over 30 minutes" ]; fhir:Dosage.timing [ fhir:Timing.repeat [ fhir:Timing.repeat.duration [ fhir:value "30"^^xsd:decimal ]; fhir:Timing.repeat.durationUnit [ fhir:value "min" ] ] ]; fhir:Dosage.route [ fhir:CodeableConcept.text [ fhir:value "IV" ] ]; fhir:Dosage.doseAndRate [ fhir:index 0; fhir:Dosage.doseAndRate.type [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/dose-rate-type" ]; fhir:Coding.code [ fhir:value "ordered" ]; fhir:Coding.display [ fhir:value "Ordered" ] ] ]; fhir:Dosage.doseAndRate.doseQuantity [ fhir:Quantity.value [ fhir:value "1250"^^xsd:decimal ]; fhir:Quantity.unit [ fhir:value "mg/m²" ] ] ] ] ], [ a fhir:ActivityDefinition; fhir:index 1; fhir:Resource.id [ fhir:value "2222" ]; fhir:ActivityDefinition.status [ fhir:value "draft" ]; fhir:ActivityDefinition.productCodeableConcept [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ]; fhir:Coding.code [ fhir:value "40048" ]; fhir:Coding.display [ fhir:value "Carboplatin" ] ]; fhir:CodeableConcept.text [ fhir:value "CARBOplatin" ] ]; fhir:ActivityDefinition.dosage [ fhir:index 0; fhir:Dosage.text [ fhir:value "AUC 5 IV over 30 minutes" ]; fhir:Dosage.timing [ fhir:Timing.repeat [ fhir:Timing.repeat.duration [ fhir:value "30"^^xsd:decimal ]; fhir:Timing.repeat.durationUnit [ fhir:value "min" ] ] ]; fhir:Dosage.route [ fhir:CodeableConcept.text [ fhir:value "IV" ] ]; fhir:Dosage.doseAndRate [ fhir:index 0; fhir:Dosage.doseAndRate.type [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/dose-rate-type" ]; fhir:Coding.code [ fhir:value "ordered" ]; fhir:Coding.display [ fhir:value "Ordered" ] ] ]; fhir:Dosage.doseAndRate.doseQuantity [ fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://example.org/fhir/AUC-dose" ]; fhir:Extension.valueInteger [ fhir:value "5"^^xsd:integer ] ] ] ] ] ]; fhir:PlanDefinition.identifier [ fhir:index 0; fhir:Identifier.system [ fhir:value "http://example.org/ordertemplates" ]; fhir:Identifier.value [ fhir:value "KDN5" ] ]; fhir:PlanDefinition.version [ fhir:value "1"]; fhir:PlanDefinition.title [ fhir:value "Gemcitabine/CARBOplatin"]; fhir:PlanDefinition.type [ fhir:CodeableConcept.text [ fhir:value "Chemotherapy Order Template" ] ]; fhir:PlanDefinition.status [ fhir:value "draft"]; fhir:PlanDefinition.experimental [ fhir:value "true"^^xsd:boolean]; fhir:PlanDefinition.publisher [ fhir:value "National Comprehensive Cancer Network, Inc."]; fhir:PlanDefinition.useContext [ fhir:index 0; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/usagecontext-group" ]; fhir:Extension.valueString [ fhir:value "A" ] ]; fhir:UsageContext.code [ fhir:Coding.system [ fhir:value "http://example.org/fhir/CodeSystem/indications" ]; fhir:Coding.code [ fhir:value "treamentSetting-or-diseaseStatus" ] ]; fhir:UsageContext.valueCodeableConcept [ fhir:CodeableConcept.text [ fhir:value "Metastatic" ] ] ], [ fhir:index 1; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/usagecontext-group" ]; fhir:Extension.valueString [ fhir:value "A" ] ]; fhir:UsageContext.code [ fhir:Coding.system [ fhir:value "http://example.org/fhir/CodeSystem/indications" ]; fhir:Coding.code [ fhir:value "disease-or-histology" ] ]; fhir:UsageContext.valueCodeableConcept [ fhir:CodeableConcept.text [ fhir:value "Collecting Duct/Medullary Subtypes" ] ] ], [ fhir:index 2; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/usagecontext-group" ]; fhir:Extension.valueString [ fhir:value "A" ] ]; fhir:UsageContext.code [ fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/usage-context-type" ]; fhir:Coding.code [ fhir:value "focus" ] ]; fhir:UsageContext.valueCodeableConcept [ fhir:CodeableConcept.text [ fhir:value "Kidney Cancer" ] ] ], [ fhir:index 3; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/usagecontext-group" ]; fhir:Extension.valueString [ fhir:value "B" ] ]; fhir:UsageContext.code [ fhir:Coding.system [ fhir:value "http://example.org/fhir/CodeSystem/indications" ]; fhir:Coding.code [ fhir:value "treatmentSetting-or-diseaseStatus" ] ]; fhir:UsageContext.valueCodeableConcept [ fhir:CodeableConcept.text [ fhir:value "Relapsed" ] ] ], [ fhir:index 4; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/usagecontext-group" ]; fhir:Extension.valueString [ fhir:value "B" ] ]; fhir:UsageContext.code [ fhir:Coding.system [ fhir:value "http://example.org/fhir/CodeSystem/indications" ]; fhir:Coding.code [ fhir:value "disease-or-histology" ] ]; fhir:UsageContext.valueCodeableConcept [ fhir:CodeableConcept.text [ fhir:value "Collecting Duct/Medullary Subtypes" ] ] ], [ fhir:index 5; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/usagecontext-group" ]; fhir:Extension.valueString [ fhir:value "B" ] ]; fhir:UsageContext.code [ fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/usage-context-type" ]; fhir:Coding.code [ fhir:value "focus" ] ]; fhir:UsageContext.valueCodeableConcept [ fhir:CodeableConcept.text [ fhir:value "Kidney Cancer – Collecting Duct/Medullary Subtypes - Metastatic" ] ] ]; fhir:PlanDefinition.copyright [ fhir:value "All rights reserved."]; fhir:PlanDefinition.approvalDate [ fhir:value "2016-07-27"^^xsd:date]; fhir:PlanDefinition.lastReviewDate [ fhir:value "2016-07-27"^^xsd:date]; fhir:PlanDefinition.author [ fhir:index 0; fhir:ContactDetail.name [ fhir:value "Lee Surprenant" ] ]; fhir:PlanDefinition.relatedArtifact [ fhir:index 0; fhir:RelatedArtifact.type [ fhir:value "derived-from" ]; fhir:RelatedArtifact.display [ fhir:value "NCCN Guidelines for Kidney Cancer. V.2.2016" ]; fhir:RelatedArtifact.document [ fhir:Attachment.url [ fhir:value "http://www.example.org/professionals/physician_gls/PDF/kidney.pdf" ] ] ], [ fhir:index 1; fhir:RelatedArtifact.type [ fhir:value "citation"; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://example.org/fhir/regimenReferenceType" ]; fhir:Extension.valueCode [ fhir:value "a" ] ] ]; fhir:RelatedArtifact.citation [ fhir:value "Oudard S, et al. J Urol. 2007;177(5):1698-702" ]; fhir:RelatedArtifact.document [ fhir:Attachment.url [ fhir:value "http://www.ncbi.nlm.nih.gov/pubmed/17437788" ] ] ]; fhir:PlanDefinition.action [ fhir:index 0; fhir:PlanDefinition.action.selectionBehavior [ fhir:value "exactly-one" ]; fhir:PlanDefinition.action.action [ fhir:index 0; fhir:PlanDefinition.action.selectionBehavior [ fhir:value "all" ]; fhir:PlanDefinition.action.action [ fhir:index 0; fhir:PlanDefinition.action.groupingBehavior [ fhir:value "sentence-group" ]; fhir:PlanDefinition.action.selectionBehavior [ fhir:value "exactly-one" ]; fhir:PlanDefinition.action.action [ fhir:index 0; fhir:Element.id [ fhir:value "cycle-definition-1" ]; fhir:PlanDefinition.action.textEquivalent [ fhir:value "21-day cycle for 6 cycles" ]; fhir:PlanDefinition.action.timingTiming [ fhir:Timing.repeat [ fhir:Timing.repeat.count [ fhir:value "6"^^xsd:positiveInteger ]; fhir:Timing.repeat.duration [ fhir:value "21"^^xsd:decimal ]; fhir:Timing.repeat.durationUnit [ fhir:value "d" ] ] ]; fhir:PlanDefinition.action.action [ fhir:index 0; fhir:Element.id [ fhir:value "action-1" ]; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/timing-daysOfCycle" ]; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "day" ]; fhir:Extension.valueInteger [ fhir:value "1"^^xsd:integer ] ], [ fhir:index 1; fhir:Extension.url [ fhir:value "day" ]; fhir:Extension.valueInteger [ fhir:value "8"^^xsd:integer ] ] ]; fhir:PlanDefinition.action.textEquivalent [ fhir:value "Gemcitabine 1250 mg/m² IV over 30 minutes on days 1 and 8" ]; fhir:PlanDefinition.action.definitionCanonical [ fhir:value "#1111" ] ], [ fhir:index 1; fhir:Element.id [ fhir:value "action-2" ]; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "http://hl7.org/fhir/StructureDefinition/timing-daysOfCycle" ]; fhir:Element.extension [ fhir:index 0; fhir:Extension.url [ fhir:value "day" ]; fhir:Extension.valueInteger [ fhir:value "1"^^xsd:integer ] ] ]; fhir:PlanDefinition.action.textEquivalent [ fhir:value "CARBOplatin AUC 5 IV over 30 minutes on Day 1" ]; fhir:PlanDefinition.action.relatedAction [ fhir:index 0; fhir:PlanDefinition.action.relatedAction.targetId [ fhir:value "action-1" ]; fhir:PlanDefinition.action.relatedAction.relationship [ fhir:value "concurrent-with-start" ] ]; fhir:PlanDefinition.action.definitionCanonical [ fhir:value "#2222" ] ] ] ] ] ]] . # - ontology header ------------------------------------------------------------ [a owl:Ontology; owl:imports fhir:fhir.ttl] . # -------------------------------------------------------------------------------------
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.