Oral Chemotherapy Order - Capecitabine - active medication with dosing by Body Surface Area (BSA) (mg/m2)

@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

[a fhir:MedicationRequest;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "medrx0309"];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: MedicationRequest</b><a name=\"medrx0309\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationRequest &quot;medrx0309&quot; </p></div><p><b>identifier</b>: id: 12345689 (OFFICIAL)</p><p><b>status</b>: active</p><p><b>intent</b>: order</p><h3>Medications</h3><table class=\"grid\"><tr><td>-</td><td><b>Reference</b></td></tr><tr><td>*</td><td><a name=\"med0321\"> </a><blockquote><p/><p><a name=\"med0321\"> </a></p><p><b>code</b>: Capecitabine (product) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#108761006)</span></p></blockquote></td></tr></table><p><b>subject</b>: <a href=\"patient-example-a.html\">Patient/pat1: Donald Duck</a> &quot;Donald DUCK&quot;</p><p><b>encounter</b>: <a href=\"encounter-example-f001-heart.html\">Encounter/f001: encounter who leads to this prescription</a></p><p><b>authoredOn</b>: 2015-01-15</p><p><b>requester</b>: <a href=\"practitioner-example-f007-sh.html\">Practitioner/f007: Patrick Pump</a> &quot;Simone HEPS&quot;</p><blockquote><p><b>dose</b></p><blockquote><p><b>dosageInstruction</b></p><p><b>sequence</b>: 1</p><p><b>text</b>: 1000 mg/m2 orally twice daily from days 1-14 of cycle</p><p><b>timing</b>: Starting 2016-01-22, Do Once per 2 days, Until 2016-02-04</p><p><b>route</b>: Oral Route <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#26643006)</span></p></blockquote></blockquote></div>"
  ];
  fhir:DomainResource.contained [
     a fhir:Medication;
     fhir:index 0;
     fhir:Resource.id [ fhir:value "med0321" ];
     fhir:Medication.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         a sct:108761006;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "108761006" ];
         fhir:Coding.display [ fhir:value "Capecitabine (product)" ]
       ]
     ]
  ];
  fhir:MedicationRequest.identifier [
     fhir:index 0;
     fhir:Identifier.use [ fhir:value "official" ];
     fhir:Identifier.system [ fhir:value "http://www.bmc.nl/portal/prescriptions" ];
     fhir:Identifier.value [ fhir:value "12345689" ]
  ];
  fhir:MedicationRequest.status [ fhir:value "active"];
  fhir:MedicationRequest.intent [ fhir:value "order"];
  fhir:MedicationRequest.medication [
     fhir:CodeableReference.reference [
       fhir:Reference.reference [ fhir:value "#med0321" ]
     ]
  ];
  fhir:MedicationRequest.subject [
     fhir:Reference.reference [ fhir:value "Patient/pat1" ];
     fhir:Reference.display [ fhir:value "Donald Duck" ]
  ];
  fhir:MedicationRequest.encounter [
     fhir:Reference.reference [ fhir:value "Encounter/f001" ];
     fhir:Reference.display [ fhir:value "encounter who leads to this prescription" ]
  ];
  fhir:MedicationRequest.authoredOn [ fhir:value "2015-01-15"^^xsd:date];
  fhir:MedicationRequest.requester [
     fhir:Reference.reference [ fhir:value "Practitioner/f007" ];
     fhir:Reference.display [ fhir:value "Patrick Pump" ]
  ];
  fhir:MedicationRequest.dose [
     fhir:MedicationRequest.dose.dosageInstruction [
       fhir:index 0;
       fhir:Dosage.sequence [ fhir:value "1"^^xsd:integer ];
       fhir:Dosage.text [ fhir:value "1000 mg/m2 orally twice daily from days 1-14 of cycle" ];
       fhir:Dosage.timing [
         fhir:Timing.repeat [
           fhir:Timing.repeat.boundsPeriod [
             fhir:Period.start [ fhir:value "2016-01-22"^^xsd:date ];
             fhir:Period.end [ fhir:value "2016-02-04"^^xsd:date ]
           ];
           fhir:Timing.repeat.frequency [ fhir:value "1"^^xsd:positiveInteger ];
           fhir:Timing.repeat.period [ fhir:value "2"^^xsd:decimal ];
           fhir:Timing.repeat.periodUnit [ fhir:value "d" ]
         ]
       ];
       fhir:Dosage.route [
         fhir:CodeableConcept.coding [
           fhir:index 0;
           a sct:26643006;
           fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
           fhir:Coding.code [ fhir:value "26643006" ];
           fhir:Coding.display [ fhir:value "Oral Route" ]
         ]
       ];
       fhir:Dosage.doseAndRate [
         fhir:index 0;
         fhir:Dosage.doseAndRate.type [
           fhir:CodeableConcept.coding [
             fhir:index 0;
             fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/dose-rate-type" ];
             fhir:Coding.code [ fhir:value "ordered" ];
             fhir:Coding.display [ fhir:value "Ordered" ]
           ]
         ];
         fhir:Dosage.doseAndRate.doseQuantity [
           fhir:Quantity.value [ fhir:value "1000"^^xsd:decimal ];
           fhir:Quantity.unit [ fhir:value "mg/m2" ];
           fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
           fhir:Quantity.code [ fhir:value "mg/m2" ]
         ]
       ]
     ]
  ]] .

# - ontology header ------------------------------------------------------------

[a owl:Ontology;
  owl:imports fhir:fhir.ttl] .

# -------------------------------------------------------------------------------------