Oral Chemotherapy Example - Manufactured Product - Xeloda - includes a reference to a substance in ingredient element (id = "medexample015")

<?xml version="1.0" encoding="UTF-8"?>

<Medication xmlns="http://hl7.org/fhir">
  <id value="medexample015"/> 
  <text> <status value="generated"/> <div xmlns="http://www.w3.org/1999/xhtml"><p> <b> Generated Narrative: Medication</b> <a name="medexample015"> </a> </p> <div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px
       solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">Resource Medication &quot;medexample015&quot; </p> </div> <p> <b> code</b> : Capecitabine 500mg oral tablet (Xeloda) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/3.1.0/CodeSystem-v3-rxNorm.html">RxNorm</a> #213293)</span> </p> <p> <b> marketingAuthorizationHolder</b> : <a name="mmanu"> </a> </p> <blockquote> <p/>  <p> <a name="mmanu"> </a> </p> <p> <b> name</b> : Medication Manufacturer</p> </blockquote> <p> <b> doseForm</b> : Tablet dose form (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a> #385055001)</span> </p> <blockquote> <p> <b> ingredient</b> </p> <h3> Items</h3> <table class="grid"><tr> <td> -</td> <td> <b> Reference</b> </td> </tr> <tr> <td> *</td> <td> <a name="sub04"> </a> <blockquote> <p/>  <p> <a name="sub04"> </a> </p> <p> <b> instance</b> : false</p> <h3> Codes</h3> <table class="grid"><tr> <td> -</td> <td> <b> Concept</b> </td> </tr> <tr> <td> *</td> <td> Capecitabine (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOMED CT</a> #386906001)</span> </td> </tr> </table> </blockquote> </td> </tr> </table> <p> <b> strength</b> : 500 mg<span style="background: LightGoldenRodYellow"> (Details: UCUM code mg = 'mg')</span> /1(unit TAB from http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm)<span style="background: LightGoldenRodYellow"> (Details: http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm code TAB = 'Tablet')</span> </p> </blockquote> <h3> Batches</h3> <table class="grid"><tr> <td> -</td> <td> <b> LotNumber</b> </td> <td> <b> ExpirationDate</b> </td> </tr> <tr> <td> *</td> <td> 9494788</td> <td> 2017-05-22</td> </tr> </table> </div> </text> <contained> 
    <Organization> 
      <id value="mmanu"/> 
      <name value="Medication Manufacturer"/> 
    </Organization> 
  </contained> 
  <contained> 
    <Substance> 
      <id value="sub04"/> 
      <instance value="false"/> 
      <code> 
        <concept> 
          <coding> 
            <system value="http://snomed.info/sct"/> 
            <code value="386906001"/> 
            <display value="Capecitabine (substance)"/> 
          </coding> 
        </concept> 
      </code> 
    </Substance> 
  </contained> 
  <code> 
    <coding> 
      <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/> 
      <code value="213293"/> 
      <display value="Capecitabine 500mg oral tablet (Xeloda)"/> 
    </coding> 
  </code> 
  <marketingAuthorizationHolder> 
    <reference value="#mmanu"/> 
  </marketingAuthorizationHolder> 
    <doseForm> 
      <coding> 
        <system value="http://snomed.info/sct"/> 
        <code value="385055001"/> 
        <display value="Tablet dose form (qualifier value)"/> 
      </coding> 
    </doseForm> 
    <ingredient> 
      <item> 
      <reference> 
        <reference value="#sub04"/> 
      </reference> 
      </item> 
      <strengthRatio> 
        <numerator> 
          <value value="500"/> 
          <system value="http://unitsofmeasure.org"/> 
          <code value="mg"/> 
        </numerator> 
        <denominator> 
          <value value="1"/> 
          <system value="http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm"/> 
          <code value="TAB"/> 
        </denominator> 
      </strengthRatio> 
    </ingredient> 
  <batch> 
    <lotNumber value="9494788"/> 
    <expirationDate value="2017-05-22"/> 
  </batch> 
</Medication>