Example realization of the KDN5 PlanDefinition example (id = "kdn5-example")

<?xml version="1.0" encoding="UTF-8"?>

<RequestOrchestration xmlns="http://hl7.org/fhir">
  <id value="kdn5-example"/> 
  <text> 
    <status value="generated"/> 
    <div xmlns="http://www.w3.org/1999/xhtml">Administer gemcitabine and carboplatin.</div> 
  </text> 
  <contained> 
    <MedicationRequest> 
      <id value="1111"/> 
      <status value="unknown"/> 
      <intent value="proposal"/> 
      <medication> 
      <concept> 
        <coding> 
          <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/> 
          <code value="12574"/> 
          <display value="gemcitabine"/> 
        </coding> 
        <text value="gemcitabine"/> 
      </concept> 
      </medication> 
      <subject> 
        <reference value="Patient/example"/> 
      </subject> 
      <dose> 
      <dosageInstruction> 
        <text value="1250 mg/m² IV over 30 minutes"/> 
        <timing> 
          <repeat> 
            <duration value="30"/> 
            <durationUnit value="min"/> 
          </repeat> 
        </timing> 
        <route> 
          <text value="IV"/> 
        </route> 
        <doseAndRate> 
          <type> 
            <coding> 
              <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/> 
              <code value="ordered"/> 
              <display value="Ordered"/> 
            </coding> 
          </type> 
          <doseQuantity> 
          <value value="1250"/> 
          <unit value="mg/m²"/> 
          </doseQuantity> 
        </doseAndRate> 
      </dosageInstruction> 
      </dose> 
    </MedicationRequest> 
  </contained> 
  <contained> 
    <MedicationRequest> 
      <id value="2222"/> 
      <status value="unknown"/> 
      <intent value="proposal"/> 
      <medication> 
      <concept> 
        <coding> 
          <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/> 
          <code value="40048"/> 
          <display value="Carboplatin"/> 
        </coding> 
        <text value="CARBOplatin"/> 
      </concept> 
      </medication> 
      <subject> 
        <reference value="Patient/example"/> 
      </subject> 
      <dose> 
      <dosageInstruction> 
        <text value="AUC 5 IV over 30 minutes"/> 
        <timing> 
          <repeat> 
            <duration value="30"/> 
            <durationUnit value="min"/> 
          </repeat> 
        </timing> 
        <route> 
          <text value="IV"/> 
        </route> 
        <doseAndRate> 
          <type> 
            <coding> 
              <system value="http://terminology.hl7.org/CodeSystem/dose-rate-type"/> 
              <code value="ordered"/> 
              <display value="Ordered"/> 
            </coding> 
          </type> 
          <doseQuantity> 
            <!--   AUC as dose unit or as an extension?   -->
            <extension url="http://example.org/fhir/AUC-dose">
              <valueInteger value="5"/> 
            </extension> 
            <!--   <value value="5" />
          <unit value="AUC" />
          <system value="http://snomed.info/sct" />
          <code value="413573002" />   -->
          </doseQuantity> 
        </doseAndRate> 

      </dosageInstruction> 
      </dose> 
    </MedicationRequest> 
  </contained> 
  <identifier> 
    <value value="requestorchestration-kdn5"/> 
  </identifier> 
  <instantiatesCanonical value="http://example.org/fhir/PlanDefinition/KDN5"/> 
  <status value="draft"/> 
  <intent value="plan"/> 
  <priority value="routine"/> 
  <subject> 
    <reference value="Patient/example"/> 
  </subject> 
  <encounter> 
    <reference value="Encounter/example"/> 
  </encounter> 
  <authoredOn value="2017-03-06T17:31:00Z"/> 
  <author> 
    <reference value="Practitioner/1"/> 
  </author> 

  <action> 
    <!--   list of regimen options. in this case only one   -->
    <selectionBehavior value="exactly-one"/> 
    <action> 
      <!--   list of regimen parts. in this case only one   -->
      <selectionBehavior value="all"/> 
      <action> 
        <!--   list of cycle definitions. in this case only one   -->
        <groupingBehavior value="sentence-group"/> 
        <selectionBehavior value="exactly-one"/> 
        <action id="cycle-definition-1">
          <textEquivalent value="21-day cycle for 6 cycles"/> 

          <timingTiming> 
            <repeat> 
              <count value="6"/> 
              <duration value="21"/> 
              <durationUnit value="d"/> 
            </repeat> 
          </timingTiming> 

          <!--   list of regimen entry references for this regimen part   -->
          <!--   references would duplicated in each cycle definition option
          (see http://hl7.org/fhir/2022Sep/codesystem-action-grouping-behavior.html#sentence-group)
            -->
          <action id="action-1">
            <extension url="http://hl7.org/fhir/StructureDefinition/timing-daysOfCycle">
              <extension url="day">
                <valueInteger value="1"/> 
              </extension> 
              <extension url="day">
                <valueInteger value="8"/> 
              </extension> 
            </extension> 
            <textEquivalent value="Gemcitabine 1250 mg/m² IV over 30 minutes on days 1 and 8"/> 
            <resource> 
              <reference value="#1111"/> 
            </resource> 
          </action> 
          <action id="action-2">
            <extension url="http://hl7.org/fhir/StructureDefinition/timing-daysOfCycle">
              <extension url="day">
                <valueInteger value="1"/> 
              </extension> 
            </extension> 
            <textEquivalent value="CARBOplatin AUC 5 IV over 30 minutes on Day 1"/> 
            <relatedAction> 
              <targetId value="action-1"/> 
              <relationship value="concurrent-with-start"/> 
      </relatedAction> 
            <resource> 
              <reference value="#2222"/> 
            </resource> 
          </action>  <!--   end of regimen entries   -->
        </action>  <!--   end of cycle definitions   -->
      </action>  <!--   end of regimen parts   -->
    </action>  <!--   end of regimen options   -->
  </action> 
</RequestOrchestration>