Order for as needed (PRN) dosage - Vicodin - completed with dosageInstruction with additionalInstruction (coded) and as needed with reason, dispenseRequest and substitution

{
  "resourceType": "MedicationRequest",
  "id": "medrx0308",
  "text": {
    "status": "generated",
    "div": "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: MedicationRequest</b><a name=\"medrx0308\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource MedicationRequest &quot;medrx0308&quot; </p></div><p><b>identifier</b>: id: 12345689 (OFFICIAL)</p><p><b>status</b>: completed</p><p><b>intent</b>: order</p><h3>Medications</h3><table class=\"grid\"><tr><td>-</td><td><b>Concept</b></td></tr><tr><td>*</td><td>Vicodin 5/500 Oral Tablet <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-rxNorm.html\">RxNorm</a>#856907)</span></td></tr></table><p><b>subject</b>: <a href=\"patient-example-a.html\">Patient/pat1: Donald Duck</a> &quot;Donald DUCK&quot;</p><p><b>encounter</b>: <a href=\"encounter-example-f001-heart.html\">Encounter/f001: encounter who leads to this prescription</a></p><p><b>authoredOn</b>: 2015-01-15</p><p><b>requester</b>: <a href=\"practitioner-example-f007-sh.html\">Practitioner/f007: Patrick Pump</a> &quot;Simone HEPS&quot;</p><p><b>recorder</b>: <a href=\"practitioner-example-f204-ce.html\">Practitioner/f204: Carla Espinoza</a> &quot;Carla Espinosa&quot;</p><blockquote><p><b>dose</b></p><blockquote><p><b>dosageInstruction</b></p><p><b>sequence</b>: 1</p><p><b>text</b>: 1 tablet every four hours as needed for pain</p><p><b>additionalInstruction</b>: Warning. May cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#418914006)</span></p><p><b>timing</b>: Do Once per 4 hours</p><p><b>asNeededFor</b>: Fibromyalgia (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#203082005)</span></p><p><b>route</b>: Oral Route <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOMED CT</a>#26643006)</span></p></blockquote></blockquote><blockquote><p><b>dispenseRequest</b></p><p><b>validityPeriod</b>: 2015-01-15 --&gt; 2016-01-15</p><p><b>quantity</b>: 30 TAB<span style=\"background: LightGoldenRodYellow\"> (Details: http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm code TAB = 'Tablet')</span></p><h3>ExpectedSupplyDurations</h3><table class=\"grid\"><tr><td>-</td><td><b>Value</b></td><td><b>Unit</b></td><td><b>System</b></td><td><b>Code</b></td></tr><tr><td>*</td><td>10</td><td>days</td><td><a href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-ucum.html\">Unified Code for Units of Measure (UCUM)</a></td><td>d</td></tr></table></blockquote><h3>Substitutions</h3><table class=\"grid\"><tr><td>-</td><td><b>Allowed[x]</b></td><td><b>Reason</b></td></tr><tr><td>*</td><td>false</td><td>formulary policy <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/3.1.0/CodeSystem-v3-ActReason.html\">ActReason</a>#FP)</span></td></tr></table></div>"
  },
  "identifier": [
    {
      "use": "official",
      "system": "http://www.bmc.nl/portal/prescriptions",
      "value": "12345689"
    }
  ],
  "status": "completed",
  "intent": "order",
  "medication": {
    "concept": {
      "coding": [
        {
          "system": "http://www.nlm.nih.gov/research/umls/rxnorm",
          "code": "856907",
          "display": "Vicodin 5/500 Oral Tablet"
        }
      ]
    }
  },
  "subject": {
    "reference": "Patient/pat1",
    "display": "Donald Duck"
  },
  "encounter": {
    "reference": "Encounter/f001",
    "display": "encounter who leads to this prescription"
  },
  "authoredOn": "2015-01-15",
  "requester": {
    "reference": "Practitioner/f007",
    "display": "Patrick Pump"
  },
  "recorder": {
    "reference": "Practitioner/f204",
    "display": "Carla Espinoza"
  },
  "dose": {
    "dosageInstruction": [
      {
        "sequence": 1,
        "text": "1 tablet every four hours as needed for pain",
        "additionalInstruction": [
          {
            "coding": [
              {
                "system": "http://snomed.info/sct",
                "code": "418914006",
                "display": "Warning. May cause drowsiness. If affected do not drive or operate machinery. Avoid alcoholic drink (qualifier value)"
              }
            ]
          }
        ],
        "timing": {
          "repeat": {
            "frequency": 1,
            "period": 4,
            "periodUnit": "h"
          }
        },
        "asNeededFor": [
          {
            "coding": [
              {
                "system": "http://snomed.info/sct",
                "code": "203082005",
                "display": "Fibromyalgia (disorder)"
              }
            ]
          }
        ],
        "route": {
          "coding": [
            {
              "system": "http://snomed.info/sct",
              "code": "26643006",
              "display": "Oral Route"
            }
          ]
        },
        "doseAndRate": [
          {
            "type": {
              "coding": [
                {
                  "system": "http://terminology.hl7.org/CodeSystem/dose-rate-type",
                  "code": "ordered",
                  "display": "Ordered"
                }
              ]
            },
            "doseQuantity": {
              "value": 1,
              "unit": "TAB",
              "system": "http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm",
              "code": "TAB"
            }
          }
        ]
      }
    ]
  },
  "dispenseRequest": {
    "validityPeriod": {
      "start": "2015-01-15",
      "end": "2016-01-15"
    },
    "quantity": {
      "value": 30,
      "unit": "TAB",
      "system": "http://terminology.hl7.org/CodeSystem/v3-orderableDrugForm",
      "code": "TAB"
    },
    "expectedSupplyDuration": {
      "value": 10,
      "unit": "days",
      "system": "http://unitsofmeasure.org",
      "code": "d"
    }
  },
  "substitution": {
    "allowedBoolean": false,
    "reason": {
      "coding": [
        {
          "system": "http://terminology.hl7.org/CodeSystem/v3-ActReason",
          "code": "FP",
          "display": "formulary policy"
        }
      ]
    }
  }
}