11.6 Resource MedicationKnowledge - Content

Name	Flags	Card.	Type	Description & Constraints
MedicationKnowledge	TU		DomainResource	Definition of Medication Knowledge Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension Interfaces Implemented: MetadataResource
identifier	Σ	0..*	Identifier	Business identifier for this medication
code	Σ	0..1	CodeableConcept	Code that identifies this medication SNOMED CT Medication Codes (Example)
status	?!Σ	0..1	code	active | entered-in-error | inactive MedicationKnowledge Status Codes (Required)
author		0..1	Reference(Organization)	Creator or owner of the knowledge or information about the medication
intendedJurisdiction		0..*	CodeableConcept	Codes that identify the different jurisdictions for which the information of this resource was created
name	Σ	0..*	string	A name associated with the medication being described
relatedMedicationKnowledge		0..*	BackboneElement	Associated or related medication information
type		1..1	CodeableConcept	Category of medicationKnowledge
reference		1..*	Reference(MedicationKnowledge)	Associated documentation about the associated medication knowledge
associatedMedication		0..*	Reference(Medication)	The set of medication resources that are associated with this medication
productType		0..*	CodeableConcept	Category of the medication or product
monograph		0..*	BackboneElement	Associated documentation about the medication
type		0..1	CodeableConcept	The category of medication document
source		0..1	Reference(DocumentReference)	Associated documentation about the medication
preparationInstruction		0..1	markdown	The instructions for preparing the medication
cost		0..*	BackboneElement	The pricing of the medication
effectiveDate		0..*	Period	The date range for which the cost is effective
type		1..1	CodeableConcept	The category of the cost information
source		0..1	string	The source or owner for the price information
cost[x]		1..1		The price or category of the cost of the medication Medication Cost Category Codes (Example)
costMoney			Money
costCodeableConcept			CodeableConcept
monitoringProgram	Σ	0..*	BackboneElement	Program under which a medication is reviewed
type		0..1	CodeableConcept	Type of program under which the medication is monitored
name		0..1	string	Name of the reviewing program
indicationGuideline		0..*	BackboneElement	Guidelines or protocols for administration of the medication for an indication
indication		0..*	CodeableReference(ClinicalUseDefinition)	Indication for use that applies to the specific administration guideline
dosingGuideline		0..*	BackboneElement	Guidelines for dosage of the medication
treatmentIntent		0..1	CodeableConcept	Intention of the treatment
dosage		0..*	BackboneElement	Dosage for the medication for the specific guidelines
type		1..1	CodeableConcept	Category of dosage for a medication
dosage		1..*	Dosage	Dosage for the medication for the specific guidelines
administrationTreatment		0..1	CodeableConcept	Type of treatment the guideline applies to
patientCharacteristic		0..*	BackboneElement	Characteristics of the patient that are relevant to the administration guidelines
type		1..1	CodeableConcept	Categorization of specific characteristic that is relevant to the administration guideline
value[x]		0..1		The specific characteristic
valueCodeableConcept			CodeableConcept
valueQuantity			Quantity
valueRange			Range
medicineClassification		0..*	BackboneElement	Categorization of the medication within a formulary or classification system
type		1..1	CodeableConcept	The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
source[x]		0..1		The source of the classification
sourceString			string
sourceUri			uri
classification		0..*	CodeableConcept	Specific category assigned to the medication
packaging		0..*	BackboneElement	Details about packaged medications
cost		0..*	see cost	Cost of the packaged medication
packagedProduct		0..1	Reference(PackagedProductDefinition)	The packaged medication that is being priced
clinicalUseIssue		0..*	Reference(ClinicalUseDefinition)	Potential clinical issue with or between medication(s)
storageGuideline		0..*	BackboneElement	How the medication should be stored
reference		0..1	uri	Reference to additional information
note		0..*	Annotation	Additional storage notes
stabilityDuration		0..1	Duration	Duration remains stable
environmentalSetting		0..*	BackboneElement	Setting or value of environment for adequate storage
type		1..1	CodeableConcept	Categorization of the setting
value[x]		1..1		Value of the setting
valueQuantity			Quantity
valueRange			Range
valueCodeableConcept			CodeableConcept
regulatory		0..*	BackboneElement	Regulatory information about a medication
regulatoryAuthority		1..1	Reference(Organization)	Specifies the authority of the regulation
substitution		0..*	BackboneElement	Specifies if changes are allowed when dispensing a medication from a regulatory perspective
type		1..1	CodeableConcept	Specifies the type of substitution allowed
allowed		1..1	boolean	Specifies if regulation allows for changes in the medication when dispensing
schedule		0..*	CodeableConcept	Specifies the schedule of a medication in jurisdiction
maxDispense		0..1	BackboneElement	The maximum number of units of the medication that can be dispensed in a period
quantity		1..1	SimpleQuantity	The maximum number of units of the medication that can be dispensed
period		0..1	Duration	The period that applies to the maximum number of units
definitional		0..1	BackboneElement	Minimal definition information about the medication
definition		0..*	Reference(MedicinalProductDefinition)	Definitional resources that provide more information about this medication
doseForm		0..1	CodeableConcept	powder | tablets | capsule + SNOMED CT Form Codes (Example)
intendedRoute		0..*	CodeableConcept	The intended or approved route of administration SNOMED CT Route Codes (Example)
ingredient	Σ	0..*	BackboneElement	Active or inactive ingredient
item	Σ	1..1	CodeableReference(Substance)	Substances contained in the medication
type		0..1	CodeableConcept	A code that defines the type of ingredient, active, base, etc. RoleClassIngredientEntity (Example)
strength[x]		0..1		Quantity of ingredient present Medication Ingredient Strength Codes (Example)
strengthRatio			Ratio
strengthCodeableConcept			CodeableConcept
strengthQuantity			Quantity
drugCharacteristic		0..*	BackboneElement	Specifies descriptive properties of the medicine
type		0..1	CodeableConcept	Code specifying the type of characteristic of medication medicationKnowledge Characteristic Codes (Example)
value[x]		0..1		Description of the characteristic
valueCodeableConcept			CodeableConcept
valueString			string
valueQuantity			SimpleQuantity
valueBase64Binary			base64Binary
valueAttachment			Attachment
Documentation for this format

See the Extensions for this resource

<MedicationKnowledge xmlns="http://hl7.org/fhir"> 
 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <identifier><!-- 0..* Identifier Business identifier for this medication --></identifier>
 <code><!-- 0..1 CodeableConcept Code that identifies this medication --></code>
 <status value="[code]"/><!-- 0..1 active | entered-in-error | inactive -->
 <author><!-- 0..1 Reference(Organization) Creator or owner of the knowledge or information about the medication --></author>
 <intendedJurisdiction><!-- 0..* CodeableConcept Codes that identify the different jurisdictions for which the information of this resource was created --></intendedJurisdiction>
 <name value="[string]"/><!-- 0..* A name associated with the medication being described -->
 <relatedMedicationKnowledge>  <!-- 0..* Associated or related medication information -->
  <type><!-- 1..1 CodeableConcept Category of medicationKnowledge --></type>
  <reference><!-- 1..* Reference(MedicationKnowledge) Associated documentation about the associated medication knowledge --></reference>
 </relatedMedicationKnowledge>
 <associatedMedication><!-- 0..* Reference(Medication) The set of medication resources that are associated with this medication --></associatedMedication>
 <productType><!-- 0..* CodeableConcept Category of the medication or product --></productType>
 <monograph>  <!-- 0..* Associated documentation about the medication -->
  <type><!-- 0..1 CodeableConcept The category of medication document --></type>
  <source><!-- 0..1 Reference(DocumentReference) Associated documentation about the medication --></source>
 </monograph>
 <preparationInstruction value="[markdown]"/><!-- 0..1 The instructions for preparing the medication -->
 <cost>  <!-- 0..* The pricing of the medication -->
  <effectiveDate><!-- 0..* Period The date range for which the cost is effective --></effectiveDate>
  <type><!-- 1..1 CodeableConcept The category of the cost information --></type>
  <source value="[string]"/><!-- 0..1 The source or owner for the price information -->
  <cost[x]><!-- 1..1 Money|CodeableConcept The price or category of the cost of the medication --></cost[x]>
 </cost>
 <monitoringProgram>  <!-- 0..* Program under which a medication is reviewed -->
  <type><!-- 0..1 CodeableConcept Type of program under which the medication is monitored --></type>
  <name value="[string]"/><!-- 0..1 Name of the reviewing program -->
 </monitoringProgram>
 <indicationGuideline>  <!-- 0..* Guidelines or protocols for administration of the medication for an indication -->
  <indication><!-- 0..* CodeableReference(ClinicalUseDefinition) Indication for use that applies to the specific administration guideline --></indication>
  <dosingGuideline>  <!-- 0..* Guidelines for dosage of the medication -->
   <treatmentIntent><!-- 0..1 CodeableConcept Intention of the treatment --></treatmentIntent>
   <dosage>  <!-- 0..* Dosage for the medication for the specific guidelines -->
    <type><!-- 1..1 CodeableConcept Category of dosage for a medication --></type>
    <dosage><!-- 1..* Dosage Dosage for the medication for the specific guidelines --></dosage>
   </dosage>
   <administrationTreatment><!-- 0..1 CodeableConcept Type of treatment the guideline applies to --></administrationTreatment>
   <patientCharacteristic>  <!-- 0..* Characteristics of the patient that are relevant to the administration guidelines -->
    <type><!-- 1..1 CodeableConcept Categorization of specific characteristic that is relevant to the administration guideline --></type>
    <value[x]><!-- 0..1 CodeableConcept|Quantity|Range The specific characteristic --></value[x]>
   </patientCharacteristic>
  </dosingGuideline>
 </indicationGuideline>
 <medicineClassification>  <!-- 0..* Categorization of the medication within a formulary or classification system -->
  <type><!-- 1..1 CodeableConcept The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification) --></type>
  <source[x]><!-- 0..1 string|uri The source of the classification --></source[x]>
  <classification><!-- 0..* CodeableConcept Specific category assigned to the medication --></classification>
 </medicineClassification>
 <packaging>  <!-- 0..* Details about packaged medications -->
  <cost><!-- 0..* Content as for MedicationKnowledge.cost Cost of the packaged medication --></cost>
  <packagedProduct><!-- 0..1 Reference(PackagedProductDefinition) The packaged medication that is being priced --></packagedProduct>
 </packaging>
 <clinicalUseIssue><!-- 0..* Reference(ClinicalUseDefinition) Potential clinical issue with or between medication(s) --></clinicalUseIssue>
 <storageGuideline>  <!-- 0..* How the medication should be stored -->
  <reference value="[uri]"/><!-- 0..1 Reference to additional information -->
  <note><!-- 0..* Annotation Additional storage notes --></note>
  <stabilityDuration><!-- 0..1 Duration Duration remains stable --></stabilityDuration>
  <environmentalSetting>  <!-- 0..* Setting or value of environment for adequate storage -->
   <type><!-- 1..1 CodeableConcept Categorization of the setting --></type>
   <value[x]><!-- 1..1 Quantity|Range|CodeableConcept Value of the setting --></value[x]>
  </environmentalSetting>
 </storageGuideline>
 <regulatory>  <!-- 0..* Regulatory information about a medication -->
  <regulatoryAuthority><!-- 1..1 Reference(Organization) Specifies the authority of the regulation --></regulatoryAuthority>
  <substitution>  <!-- 0..* Specifies if changes are allowed when dispensing a medication from a regulatory perspective -->
   <type><!-- 1..1 CodeableConcept Specifies the type of substitution allowed --></type>
   <allowed value="[boolean]"/><!-- 1..1 Specifies if regulation allows for changes in the medication when dispensing -->
  </substitution>
  <schedule><!-- 0..* CodeableConcept Specifies the schedule of a medication in jurisdiction --></schedule>
  <maxDispense>  <!-- 0..1 The maximum number of units of the medication that can be dispensed in a period -->
   <quantity><!-- 1..1 Quantity(SimpleQuantity) The maximum number of units of the medication that can be dispensed --></quantity>
   <period><!-- 0..1 Duration The period that applies to the maximum number of units --></period>
  </maxDispense>
 </regulatory>
 <definitional>  <!-- 0..1 Minimal definition information about the medication -->
  <definition><!-- 0..* Reference(MedicinalProductDefinition) Definitional resources that provide more information about this medication --></definition>
  <doseForm><!-- 0..1 CodeableConcept powder | tablets | capsule + --></doseForm>
  <intendedRoute><!-- 0..* CodeableConcept The intended or approved route of administration --></intendedRoute>
  <ingredient>  <!-- 0..* Active or inactive ingredient -->
   <item><!-- 1..1 CodeableReference(Substance) Substances contained in the medication --></item>
   <type><!-- 0..1 CodeableConcept A code that defines the type of ingredient, active, base, etc.  --></type>
   <strength[x]><!-- 0..1 Ratio|CodeableConcept|Quantity Quantity of ingredient present --></strength[x]>
  </ingredient>
  <drugCharacteristic>  <!-- 0..* Specifies descriptive properties of the medicine -->
   <type><!-- 0..1 CodeableConcept Code specifying the type of characteristic of medication --></type>
   <value[x]><!-- 0..1 CodeableConcept|string|Quantity(SimpleQuantity)|
     base64Binary|Attachment Description of the characteristic --></value[x]>
  </drugCharacteristic>
 </definitional>
</MedicationKnowledge>

{
  "resourceType" : "MedicationKnowledge",
  // from Resource: id, meta, implicitRules, and language
  // from DomainResource: text, contained, extension, and modifierExtension
  "identifier" : [{ Identifier }], // Business identifier for this medication
  "code" : { CodeableConcept }, // Code that identifies this medication
  "status" : "<code>", // active | entered-in-error | inactive
  "author" : { Reference(Organization) }, // Creator or owner of the knowledge or information about the medication
  "intendedJurisdiction" : [{ CodeableConcept }], // Codes that identify the different jurisdictions for which the information of this resource was created
  "name" : ["<string>"], // A name associated with the medication being described
  "relatedMedicationKnowledge" : [{ // Associated or related medication information
    "type" : { CodeableConcept }, // R!  Category of medicationKnowledge
    "reference" : [{ Reference(MedicationKnowledge) }] // R!  Associated documentation about the associated medication knowledge
  }],
  "associatedMedication" : [{ Reference(Medication) }], // The set of medication resources that are associated with this medication
  "productType" : [{ CodeableConcept }], // Category of the medication or product
  "monograph" : [{ // Associated documentation about the medication
    "type" : { CodeableConcept }, // The category of medication document
    "source" : { Reference(DocumentReference) } // Associated documentation about the medication
  }],
  "preparationInstruction" : "<markdown>", // The instructions for preparing the medication
  "cost" : [{ // The pricing of the medication
    "effectiveDate" : [{ Period }], // The date range for which the cost is effective
    "type" : { CodeableConcept }, // R!  The category of the cost information
    "source" : "<string>", // The source or owner for the price information
    // cost[x]: The price or category of the cost of the medication. One of these 2:
    "costMoney" : { Money },
    "costCodeableConcept" : { CodeableConcept }
  }],
  "monitoringProgram" : [{ // Program under which a medication is reviewed
    "type" : { CodeableConcept }, // Type of program under which the medication is monitored
    "name" : "<string>" // Name of the reviewing program
  }],
  "indicationGuideline" : [{ // Guidelines or protocols for administration of the medication for an indication
    "indication" : [{ CodeableReference(ClinicalUseDefinition) }], // Indication for use that applies to the specific administration guideline
    "dosingGuideline" : [{ // Guidelines for dosage of the medication
      "treatmentIntent" : { CodeableConcept }, // Intention of the treatment
      "dosage" : [{ // Dosage for the medication for the specific guidelines
        "type" : { CodeableConcept }, // R!  Category of dosage for a medication
        "dosage" : [{ Dosage }] // R!  Dosage for the medication for the specific guidelines
      }],
      "administrationTreatment" : { CodeableConcept }, // Type of treatment the guideline applies to
      "patientCharacteristic" : [{ // Characteristics of the patient that are relevant to the administration guidelines
        "type" : { CodeableConcept }, // R!  Categorization of specific characteristic that is relevant to the administration guideline
        // value[x]: The specific characteristic. One of these 3:
        "valueCodeableConcept" : { CodeableConcept },
        "valueQuantity" : { Quantity },
        "valueRange" : { Range }
      }]
    }]
  }],
  "medicineClassification" : [{ // Categorization of the medication within a formulary or classification system
    "type" : { CodeableConcept }, // R!  The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
    // source[x]: The source of the classification. One of these 2:
    "sourceString" : "<string>",
    "sourceUri" : "<uri>",
    "classification" : [{ CodeableConcept }] // Specific category assigned to the medication
  }],
  "packaging" : [{ // Details about packaged medications
    "cost" : [{ Content as for MedicationKnowledge.cost }], // Cost of the packaged medication
    "packagedProduct" : { Reference(PackagedProductDefinition) } // The packaged medication that is being priced
  }],
  "clinicalUseIssue" : [{ Reference(ClinicalUseDefinition) }], // Potential clinical issue with or between medication(s)
  "storageGuideline" : [{ // How the medication should be stored
    "reference" : "<uri>", // Reference to additional information
    "note" : [{ Annotation }], // Additional storage notes
    "stabilityDuration" : { Duration }, // Duration remains stable
    "environmentalSetting" : [{ // Setting or value of environment for adequate storage
      "type" : { CodeableConcept }, // R!  Categorization of the setting
      // value[x]: Value of the setting. One of these 3:
      "valueQuantity" : { Quantity },
      "valueRange" : { Range },
      "valueCodeableConcept" : { CodeableConcept }
    }]
  }],
  "regulatory" : [{ // Regulatory information about a medication
    "regulatoryAuthority" : { Reference(Organization) }, // R!  Specifies the authority of the regulation
    "substitution" : [{ // Specifies if changes are allowed when dispensing a medication from a regulatory perspective
      "type" : { CodeableConcept }, // R!  Specifies the type of substitution allowed
      "allowed" : <boolean> // R!  Specifies if regulation allows for changes in the medication when dispensing
    }],
    "schedule" : [{ CodeableConcept }], // Specifies the schedule of a medication in jurisdiction
    "maxDispense" : { // The maximum number of units of the medication that can be dispensed in a period
      "quantity" : { Quantity(SimpleQuantity) }, // R!  The maximum number of units of the medication that can be dispensed
      "period" : { Duration } // The period that applies to the maximum number of units
    }
  }],
  "definitional" : { // Minimal definition information about the medication
    "definition" : [{ Reference(MedicinalProductDefinition) }], // Definitional resources that provide more information about this medication
    "doseForm" : { CodeableConcept }, // powder | tablets | capsule +
    "intendedRoute" : [{ CodeableConcept }], // The intended or approved route of administration
    "ingredient" : [{ // Active or inactive ingredient
      "item" : { CodeableReference(Substance) }, // R!  Substances contained in the medication
      "type" : { CodeableConcept }, // A code that defines the type of ingredient, active, base, etc. 
      // strength[x]: Quantity of ingredient present. One of these 3:
      "strengthRatio" : { Ratio },
      "strengthCodeableConcept" : { CodeableConcept },
      "strengthQuantity" : { Quantity }
    }],
    "drugCharacteristic" : [{ // Specifies descriptive properties of the medicine
      "type" : { CodeableConcept }, // Code specifying the type of characteristic of medication
      // value[x]: Description of the characteristic. One of these 5:
      "valueCodeableConcept" : { CodeableConcept },
      "valueString" : "<string>",
      "valueQuantity" : { Quantity(SimpleQuantity) },
      "valueBase64Binary" : "<base64Binary>",
      "valueAttachment" : { Attachment }
    }]
  }
}

@prefix fhir: <http://hl7.org/fhir/> .


[ a fhir:MedicationKnowledge;
  fhir:nodeRole fhir:treeRoot; # if this is the parser root

  # from Resource: .id, .meta, .implicitRules, and .language
  # from DomainResource: .text, .contained, .extension, and .modifierExtension
  fhir:MedicationKnowledge.identifier [ Identifier ], ... ; # 0..* Business identifier for this medication
  fhir:MedicationKnowledge.code [ CodeableConcept ]; # 0..1 Code that identifies this medication
  fhir:MedicationKnowledge.status [ code ]; # 0..1 active | entered-in-error | inactive
  fhir:MedicationKnowledge.author [ Reference(Organization) ]; # 0..1 Creator or owner of the knowledge or information about the medication
  fhir:MedicationKnowledge.intendedJurisdiction [ CodeableConcept ], ... ; # 0..* Codes that identify the different jurisdictions for which the information of this resource was created
  fhir:MedicationKnowledge.name [ string ], ... ; # 0..* A name associated with the medication being described
  fhir:MedicationKnowledge.relatedMedicationKnowledge [ # 0..* Associated or related medication information
    fhir:MedicationKnowledge.relatedMedicationKnowledge.type [ CodeableConcept ]; # 1..1 Category of medicationKnowledge
    fhir:MedicationKnowledge.relatedMedicationKnowledge.reference [ Reference(MedicationKnowledge) ], ... ; # 1..* Associated documentation about the associated medication knowledge
  ], ...;
  fhir:MedicationKnowledge.associatedMedication [ Reference(Medication) ], ... ; # 0..* The set of medication resources that are associated with this medication
  fhir:MedicationKnowledge.productType [ CodeableConcept ], ... ; # 0..* Category of the medication or product
  fhir:MedicationKnowledge.monograph [ # 0..* Associated documentation about the medication
    fhir:MedicationKnowledge.monograph.type [ CodeableConcept ]; # 0..1 The category of medication document
    fhir:MedicationKnowledge.monograph.source [ Reference(DocumentReference) ]; # 0..1 Associated documentation about the medication
  ], ...;
  fhir:MedicationKnowledge.preparationInstruction [ markdown ]; # 0..1 The instructions for preparing the medication
  fhir:MedicationKnowledge.cost [ # 0..* The pricing of the medication
    fhir:MedicationKnowledge.cost.effectiveDate [ Period ], ... ; # 0..* The date range for which the cost is effective
    fhir:MedicationKnowledge.cost.type [ CodeableConcept ]; # 1..1 The category of the cost information
    fhir:MedicationKnowledge.cost.source [ string ]; # 0..1 The source or owner for the price information
    # MedicationKnowledge.cost.cost[x] : 1..1 The price or category of the cost of the medication. One of these 2
      fhir:MedicationKnowledge.cost.costMoney [ Money ]
      fhir:MedicationKnowledge.cost.costCodeableConcept [ CodeableConcept ]
  ], ...;
  fhir:MedicationKnowledge.monitoringProgram [ # 0..* Program under which a medication is reviewed
    fhir:MedicationKnowledge.monitoringProgram.type [ CodeableConcept ]; # 0..1 Type of program under which the medication is monitored
    fhir:MedicationKnowledge.monitoringProgram.name [ string ]; # 0..1 Name of the reviewing program
  ], ...;
  fhir:MedicationKnowledge.indicationGuideline [ # 0..* Guidelines or protocols for administration of the medication for an indication
    fhir:MedicationKnowledge.indicationGuideline.indication [ CodeableReference(ClinicalUseDefinition) ], ... ; # 0..* Indication for use that applies to the specific administration guideline
    fhir:MedicationKnowledge.indicationGuideline.dosingGuideline [ # 0..* Guidelines for dosage of the medication
      fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.treatmentIntent [ CodeableConcept ]; # 0..1 Intention of the treatment
      fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.dosage [ # 0..* Dosage for the medication for the specific guidelines
        fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.dosage.type [ CodeableConcept ]; # 1..1 Category of dosage for a medication
        fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.dosage.dosage [ Dosage ], ... ; # 1..* Dosage for the medication for the specific guidelines
      ], ...;
      fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.administrationTreatment [ CodeableConcept ]; # 0..1 Type of treatment the guideline applies to
      fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic [ # 0..* Characteristics of the patient that are relevant to the administration guidelines
        fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.type [ CodeableConcept ]; # 1..1 Categorization of specific characteristic that is relevant to the administration guideline
        # MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.value[x] : 0..1 The specific characteristic. One of these 3
          fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.valueCodeableConcept [ CodeableConcept ]
          fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.valueQuantity [ Quantity ]
          fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.valueRange [ Range ]
      ], ...;
    ], ...;
  ], ...;
  fhir:MedicationKnowledge.medicineClassification [ # 0..* Categorization of the medication within a formulary or classification system
    fhir:MedicationKnowledge.medicineClassification.type [ CodeableConcept ]; # 1..1 The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
    # MedicationKnowledge.medicineClassification.source[x] : 0..1 The source of the classification. One of these 2
      fhir:MedicationKnowledge.medicineClassification.sourceString [ string ]
      fhir:MedicationKnowledge.medicineClassification.sourceUri [ uri ]
    fhir:MedicationKnowledge.medicineClassification.classification [ CodeableConcept ], ... ; # 0..* Specific category assigned to the medication
  ], ...;
  fhir:MedicationKnowledge.packaging [ # 0..* Details about packaged medications
    fhir:MedicationKnowledge.packaging.cost [ See MedicationKnowledge.cost ], ... ; # 0..* Cost of the packaged medication
    fhir:MedicationKnowledge.packaging.packagedProduct [ Reference(PackagedProductDefinition) ]; # 0..1 The packaged medication that is being priced
  ], ...;
  fhir:MedicationKnowledge.clinicalUseIssue [ Reference(ClinicalUseDefinition) ], ... ; # 0..* Potential clinical issue with or between medication(s)
  fhir:MedicationKnowledge.storageGuideline [ # 0..* How the medication should be stored
    fhir:MedicationKnowledge.storageGuideline.reference [ uri ]; # 0..1 Reference to additional information
    fhir:MedicationKnowledge.storageGuideline.note [ Annotation ], ... ; # 0..* Additional storage notes
    fhir:MedicationKnowledge.storageGuideline.stabilityDuration [ Duration ]; # 0..1 Duration remains stable
    fhir:MedicationKnowledge.storageGuideline.environmentalSetting [ # 0..* Setting or value of environment for adequate storage
      fhir:MedicationKnowledge.storageGuideline.environmentalSetting.type [ CodeableConcept ]; # 1..1 Categorization of the setting
      # MedicationKnowledge.storageGuideline.environmentalSetting.value[x] : 1..1 Value of the setting. One of these 3
        fhir:MedicationKnowledge.storageGuideline.environmentalSetting.valueQuantity [ Quantity ]
        fhir:MedicationKnowledge.storageGuideline.environmentalSetting.valueRange [ Range ]
        fhir:MedicationKnowledge.storageGuideline.environmentalSetting.valueCodeableConcept [ CodeableConcept ]
    ], ...;
  ], ...;
  fhir:MedicationKnowledge.regulatory [ # 0..* Regulatory information about a medication
    fhir:MedicationKnowledge.regulatory.regulatoryAuthority [ Reference(Organization) ]; # 1..1 Specifies the authority of the regulation
    fhir:MedicationKnowledge.regulatory.substitution [ # 0..* Specifies if changes are allowed when dispensing a medication from a regulatory perspective
      fhir:MedicationKnowledge.regulatory.substitution.type [ CodeableConcept ]; # 1..1 Specifies the type of substitution allowed
      fhir:MedicationKnowledge.regulatory.substitution.allowed [ boolean ]; # 1..1 Specifies if regulation allows for changes in the medication when dispensing
    ], ...;
    fhir:MedicationKnowledge.regulatory.schedule [ CodeableConcept ], ... ; # 0..* Specifies the schedule of a medication in jurisdiction
    fhir:MedicationKnowledge.regulatory.maxDispense [ # 0..1 The maximum number of units of the medication that can be dispensed in a period
      fhir:MedicationKnowledge.regulatory.maxDispense.quantity [ Quantity(SimpleQuantity) ]; # 1..1 The maximum number of units of the medication that can be dispensed
      fhir:MedicationKnowledge.regulatory.maxDispense.period [ Duration ]; # 0..1 The period that applies to the maximum number of units
    ];
  ], ...;
  fhir:MedicationKnowledge.definitional [ # 0..1 Minimal definition information about the medication
    fhir:MedicationKnowledge.definitional.definition [ Reference(MedicinalProductDefinition) ], ... ; # 0..* Definitional resources that provide more information about this medication
    fhir:MedicationKnowledge.definitional.doseForm [ CodeableConcept ]; # 0..1 powder | tablets | capsule +
    fhir:MedicationKnowledge.definitional.intendedRoute [ CodeableConcept ], ... ; # 0..* The intended or approved route of administration
    fhir:MedicationKnowledge.definitional.ingredient [ # 0..* Active or inactive ingredient
      fhir:MedicationKnowledge.definitional.ingredient.item [ CodeableReference(Substance) ]; # 1..1 Substances contained in the medication
      fhir:MedicationKnowledge.definitional.ingredient.type [ CodeableConcept ]; # 0..1 A code that defines the type of ingredient, active, base, etc.
      # MedicationKnowledge.definitional.ingredient.strength[x] : 0..1 Quantity of ingredient present. One of these 3
        fhir:MedicationKnowledge.definitional.ingredient.strengthRatio [ Ratio ]
        fhir:MedicationKnowledge.definitional.ingredient.strengthCodeableConcept [ CodeableConcept ]
        fhir:MedicationKnowledge.definitional.ingredient.strengthQuantity [ Quantity ]
    ], ...;
    fhir:MedicationKnowledge.definitional.drugCharacteristic [ # 0..* Specifies descriptive properties of the medicine
      fhir:MedicationKnowledge.definitional.drugCharacteristic.type [ CodeableConcept ]; # 0..1 Code specifying the type of characteristic of medication
      # MedicationKnowledge.definitional.drugCharacteristic.value[x] : 0..1 Description of the characteristic. One of these 5
        fhir:MedicationKnowledge.definitional.drugCharacteristic.valueCodeableConcept [ CodeableConcept ]
        fhir:MedicationKnowledge.definitional.drugCharacteristic.valueString [ string ]
        fhir:MedicationKnowledge.definitional.drugCharacteristic.valueSimpleQuantity [ Quantity(SimpleQuantity) ]
        fhir:MedicationKnowledge.definitional.drugCharacteristic.valueBase64Binary [ base64Binary ]
        fhir:MedicationKnowledge.definitional.drugCharacteristic.valueAttachment [ Attachment ]
    ], ...;
  ];
]

See the Full Difference for further information

This analysis is available as XML or JSON.

Name	Flags	Card.	Type	Description & Constraints
MedicationKnowledge	TU		DomainResource	Definition of Medication Knowledge Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension Interfaces Implemented: MetadataResource
identifier	Σ	0..*	Identifier	Business identifier for this medication
code	Σ	0..1	CodeableConcept	Code that identifies this medication SNOMED CT Medication Codes (Example)
status	?!Σ	0..1	code	active | entered-in-error | inactive MedicationKnowledge Status Codes (Required)
author		0..1	Reference(Organization)	Creator or owner of the knowledge or information about the medication
intendedJurisdiction		0..*	CodeableConcept	Codes that identify the different jurisdictions for which the information of this resource was created
name	Σ	0..*	string	A name associated with the medication being described
relatedMedicationKnowledge		0..*	BackboneElement	Associated or related medication information
type		1..1	CodeableConcept	Category of medicationKnowledge
reference		1..*	Reference(MedicationKnowledge)	Associated documentation about the associated medication knowledge
associatedMedication		0..*	Reference(Medication)	The set of medication resources that are associated with this medication
productType		0..*	CodeableConcept	Category of the medication or product
monograph		0..*	BackboneElement	Associated documentation about the medication
type		0..1	CodeableConcept	The category of medication document
source		0..1	Reference(DocumentReference)	Associated documentation about the medication
preparationInstruction		0..1	markdown	The instructions for preparing the medication
cost		0..*	BackboneElement	The pricing of the medication
effectiveDate		0..*	Period	The date range for which the cost is effective
type		1..1	CodeableConcept	The category of the cost information
source		0..1	string	The source or owner for the price information
cost[x]		1..1		The price or category of the cost of the medication Medication Cost Category Codes (Example)
costMoney			Money
costCodeableConcept			CodeableConcept
monitoringProgram	Σ	0..*	BackboneElement	Program under which a medication is reviewed
type		0..1	CodeableConcept	Type of program under which the medication is monitored
name		0..1	string	Name of the reviewing program
indicationGuideline		0..*	BackboneElement	Guidelines or protocols for administration of the medication for an indication
indication		0..*	CodeableReference(ClinicalUseDefinition)	Indication for use that applies to the specific administration guideline
dosingGuideline		0..*	BackboneElement	Guidelines for dosage of the medication
treatmentIntent		0..1	CodeableConcept	Intention of the treatment
dosage		0..*	BackboneElement	Dosage for the medication for the specific guidelines
type		1..1	CodeableConcept	Category of dosage for a medication
dosage		1..*	Dosage	Dosage for the medication for the specific guidelines
administrationTreatment		0..1	CodeableConcept	Type of treatment the guideline applies to
patientCharacteristic		0..*	BackboneElement	Characteristics of the patient that are relevant to the administration guidelines
type		1..1	CodeableConcept	Categorization of specific characteristic that is relevant to the administration guideline
value[x]		0..1		The specific characteristic
valueCodeableConcept			CodeableConcept
valueQuantity			Quantity
valueRange			Range
medicineClassification		0..*	BackboneElement	Categorization of the medication within a formulary or classification system
type		1..1	CodeableConcept	The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
source[x]		0..1		The source of the classification
sourceString			string
sourceUri			uri
classification		0..*	CodeableConcept	Specific category assigned to the medication
packaging		0..*	BackboneElement	Details about packaged medications
cost		0..*	see cost	Cost of the packaged medication
packagedProduct		0..1	Reference(PackagedProductDefinition)	The packaged medication that is being priced
clinicalUseIssue		0..*	Reference(ClinicalUseDefinition)	Potential clinical issue with or between medication(s)
storageGuideline		0..*	BackboneElement	How the medication should be stored
reference		0..1	uri	Reference to additional information
note		0..*	Annotation	Additional storage notes
stabilityDuration		0..1	Duration	Duration remains stable
environmentalSetting		0..*	BackboneElement	Setting or value of environment for adequate storage
type		1..1	CodeableConcept	Categorization of the setting
value[x]		1..1		Value of the setting
valueQuantity			Quantity
valueRange			Range
valueCodeableConcept			CodeableConcept
regulatory		0..*	BackboneElement	Regulatory information about a medication
regulatoryAuthority		1..1	Reference(Organization)	Specifies the authority of the regulation
substitution		0..*	BackboneElement	Specifies if changes are allowed when dispensing a medication from a regulatory perspective
type		1..1	CodeableConcept	Specifies the type of substitution allowed
allowed		1..1	boolean	Specifies if regulation allows for changes in the medication when dispensing
schedule		0..*	CodeableConcept	Specifies the schedule of a medication in jurisdiction
maxDispense		0..1	BackboneElement	The maximum number of units of the medication that can be dispensed in a period
quantity		1..1	SimpleQuantity	The maximum number of units of the medication that can be dispensed
period		0..1	Duration	The period that applies to the maximum number of units
definitional		0..1	BackboneElement	Minimal definition information about the medication
definition		0..*	Reference(MedicinalProductDefinition)	Definitional resources that provide more information about this medication
doseForm		0..1	CodeableConcept	powder | tablets | capsule + SNOMED CT Form Codes (Example)
intendedRoute		0..*	CodeableConcept	The intended or approved route of administration SNOMED CT Route Codes (Example)
ingredient	Σ	0..*	BackboneElement	Active or inactive ingredient
item	Σ	1..1	CodeableReference(Substance)	Substances contained in the medication
type		0..1	CodeableConcept	A code that defines the type of ingredient, active, base, etc. RoleClassIngredientEntity (Example)
strength[x]		0..1		Quantity of ingredient present Medication Ingredient Strength Codes (Example)
strengthRatio			Ratio
strengthCodeableConcept			CodeableConcept
strengthQuantity			Quantity
drugCharacteristic		0..*	BackboneElement	Specifies descriptive properties of the medicine
type		0..1	CodeableConcept	Code specifying the type of characteristic of medication medicationKnowledge Characteristic Codes (Example)
value[x]		0..1		Description of the characteristic
valueCodeableConcept			CodeableConcept
valueString			string
valueQuantity			SimpleQuantity
valueBase64Binary			base64Binary
valueAttachment			Attachment
Documentation for this format

See the Extensions for this resource

<MedicationKnowledge xmlns="http://hl7.org/fhir"> 
 <!-- from Resource: id, meta, implicitRules, and language -->
 <!-- from DomainResource: text, contained, extension, and modifierExtension -->
 <identifier><!-- 0..* Identifier Business identifier for this medication --></identifier>
 <code><!-- 0..1 CodeableConcept Code that identifies this medication --></code>
 <status value="[code]"/><!-- 0..1 active | entered-in-error | inactive -->
 <author><!-- 0..1 Reference(Organization) Creator or owner of the knowledge or information about the medication --></author>
 <intendedJurisdiction><!-- 0..* CodeableConcept Codes that identify the different jurisdictions for which the information of this resource was created --></intendedJurisdiction>
 <name value="[string]"/><!-- 0..* A name associated with the medication being described -->
 <relatedMedicationKnowledge>  <!-- 0..* Associated or related medication information -->
  <type><!-- 1..1 CodeableConcept Category of medicationKnowledge --></type>
  <reference><!-- 1..* Reference(MedicationKnowledge) Associated documentation about the associated medication knowledge --></reference>
 </relatedMedicationKnowledge>
 <associatedMedication><!-- 0..* Reference(Medication) The set of medication resources that are associated with this medication --></associatedMedication>
 <productType><!-- 0..* CodeableConcept Category of the medication or product --></productType>
 <monograph>  <!-- 0..* Associated documentation about the medication -->
  <type><!-- 0..1 CodeableConcept The category of medication document --></type>
  <source><!-- 0..1 Reference(DocumentReference) Associated documentation about the medication --></source>
 </monograph>
 <preparationInstruction value="[markdown]"/><!-- 0..1 The instructions for preparing the medication -->
 <cost>  <!-- 0..* The pricing of the medication -->
  <effectiveDate><!-- 0..* Period The date range for which the cost is effective --></effectiveDate>
  <type><!-- 1..1 CodeableConcept The category of the cost information --></type>
  <source value="[string]"/><!-- 0..1 The source or owner for the price information -->
  <cost[x]><!-- 1..1 Money|CodeableConcept The price or category of the cost of the medication --></cost[x]>
 </cost>
 <monitoringProgram>  <!-- 0..* Program under which a medication is reviewed -->
  <type><!-- 0..1 CodeableConcept Type of program under which the medication is monitored --></type>
  <name value="[string]"/><!-- 0..1 Name of the reviewing program -->
 </monitoringProgram>
 <indicationGuideline>  <!-- 0..* Guidelines or protocols for administration of the medication for an indication -->
  <indication><!-- 0..* CodeableReference(ClinicalUseDefinition) Indication for use that applies to the specific administration guideline --></indication>
  <dosingGuideline>  <!-- 0..* Guidelines for dosage of the medication -->
   <treatmentIntent><!-- 0..1 CodeableConcept Intention of the treatment --></treatmentIntent>
   <dosage>  <!-- 0..* Dosage for the medication for the specific guidelines -->
    <type><!-- 1..1 CodeableConcept Category of dosage for a medication --></type>
    <dosage><!-- 1..* Dosage Dosage for the medication for the specific guidelines --></dosage>
   </dosage>
   <administrationTreatment><!-- 0..1 CodeableConcept Type of treatment the guideline applies to --></administrationTreatment>
   <patientCharacteristic>  <!-- 0..* Characteristics of the patient that are relevant to the administration guidelines -->
    <type><!-- 1..1 CodeableConcept Categorization of specific characteristic that is relevant to the administration guideline --></type>
    <value[x]><!-- 0..1 CodeableConcept|Quantity|Range The specific characteristic --></value[x]>
   </patientCharacteristic>
  </dosingGuideline>
 </indicationGuideline>
 <medicineClassification>  <!-- 0..* Categorization of the medication within a formulary or classification system -->
  <type><!-- 1..1 CodeableConcept The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification) --></type>
  <source[x]><!-- 0..1 string|uri The source of the classification --></source[x]>
  <classification><!-- 0..* CodeableConcept Specific category assigned to the medication --></classification>
 </medicineClassification>
 <packaging>  <!-- 0..* Details about packaged medications -->
  <cost><!-- 0..* Content as for MedicationKnowledge.cost Cost of the packaged medication --></cost>
  <packagedProduct><!-- 0..1 Reference(PackagedProductDefinition) The packaged medication that is being priced --></packagedProduct>
 </packaging>
 <clinicalUseIssue><!-- 0..* Reference(ClinicalUseDefinition) Potential clinical issue with or between medication(s) --></clinicalUseIssue>
 <storageGuideline>  <!-- 0..* How the medication should be stored -->
  <reference value="[uri]"/><!-- 0..1 Reference to additional information -->
  <note><!-- 0..* Annotation Additional storage notes --></note>
  <stabilityDuration><!-- 0..1 Duration Duration remains stable --></stabilityDuration>
  <environmentalSetting>  <!-- 0..* Setting or value of environment for adequate storage -->
   <type><!-- 1..1 CodeableConcept Categorization of the setting --></type>
   <value[x]><!-- 1..1 Quantity|Range|CodeableConcept Value of the setting --></value[x]>
  </environmentalSetting>
 </storageGuideline>
 <regulatory>  <!-- 0..* Regulatory information about a medication -->
  <regulatoryAuthority><!-- 1..1 Reference(Organization) Specifies the authority of the regulation --></regulatoryAuthority>
  <substitution>  <!-- 0..* Specifies if changes are allowed when dispensing a medication from a regulatory perspective -->
   <type><!-- 1..1 CodeableConcept Specifies the type of substitution allowed --></type>
   <allowed value="[boolean]"/><!-- 1..1 Specifies if regulation allows for changes in the medication when dispensing -->
  </substitution>
  <schedule><!-- 0..* CodeableConcept Specifies the schedule of a medication in jurisdiction --></schedule>
  <maxDispense>  <!-- 0..1 The maximum number of units of the medication that can be dispensed in a period -->
   <quantity><!-- 1..1 Quantity(SimpleQuantity) The maximum number of units of the medication that can be dispensed --></quantity>
   <period><!-- 0..1 Duration The period that applies to the maximum number of units --></period>
  </maxDispense>
 </regulatory>
 <definitional>  <!-- 0..1 Minimal definition information about the medication -->
  <definition><!-- 0..* Reference(MedicinalProductDefinition) Definitional resources that provide more information about this medication --></definition>
  <doseForm><!-- 0..1 CodeableConcept powder | tablets | capsule + --></doseForm>
  <intendedRoute><!-- 0..* CodeableConcept The intended or approved route of administration --></intendedRoute>
  <ingredient>  <!-- 0..* Active or inactive ingredient -->
   <item><!-- 1..1 CodeableReference(Substance) Substances contained in the medication --></item>
   <type><!-- 0..1 CodeableConcept A code that defines the type of ingredient, active, base, etc.  --></type>
   <strength[x]><!-- 0..1 Ratio|CodeableConcept|Quantity Quantity of ingredient present --></strength[x]>
  </ingredient>
  <drugCharacteristic>  <!-- 0..* Specifies descriptive properties of the medicine -->
   <type><!-- 0..1 CodeableConcept Code specifying the type of characteristic of medication --></type>
   <value[x]><!-- 0..1 CodeableConcept|string|Quantity(SimpleQuantity)|
     base64Binary|Attachment Description of the characteristic --></value[x]>
  </drugCharacteristic>
 </definitional>
</MedicationKnowledge>

{
  "resourceType" : "MedicationKnowledge",
  // from Resource: id, meta, implicitRules, and language
  // from DomainResource: text, contained, extension, and modifierExtension
  "identifier" : [{ Identifier }], // Business identifier for this medication
  "code" : { CodeableConcept }, // Code that identifies this medication
  "status" : "<code>", // active | entered-in-error | inactive
  "author" : { Reference(Organization) }, // Creator or owner of the knowledge or information about the medication
  "intendedJurisdiction" : [{ CodeableConcept }], // Codes that identify the different jurisdictions for which the information of this resource was created
  "name" : ["<string>"], // A name associated with the medication being described
  "relatedMedicationKnowledge" : [{ // Associated or related medication information
    "type" : { CodeableConcept }, // R!  Category of medicationKnowledge
    "reference" : [{ Reference(MedicationKnowledge) }] // R!  Associated documentation about the associated medication knowledge
  }],
  "associatedMedication" : [{ Reference(Medication) }], // The set of medication resources that are associated with this medication
  "productType" : [{ CodeableConcept }], // Category of the medication or product
  "monograph" : [{ // Associated documentation about the medication
    "type" : { CodeableConcept }, // The category of medication document
    "source" : { Reference(DocumentReference) } // Associated documentation about the medication
  }],
  "preparationInstruction" : "<markdown>", // The instructions for preparing the medication
  "cost" : [{ // The pricing of the medication
    "effectiveDate" : [{ Period }], // The date range for which the cost is effective
    "type" : { CodeableConcept }, // R!  The category of the cost information
    "source" : "<string>", // The source or owner for the price information
    // cost[x]: The price or category of the cost of the medication. One of these 2:
    "costMoney" : { Money },
    "costCodeableConcept" : { CodeableConcept }
  }],
  "monitoringProgram" : [{ // Program under which a medication is reviewed
    "type" : { CodeableConcept }, // Type of program under which the medication is monitored
    "name" : "<string>" // Name of the reviewing program
  }],
  "indicationGuideline" : [{ // Guidelines or protocols for administration of the medication for an indication
    "indication" : [{ CodeableReference(ClinicalUseDefinition) }], // Indication for use that applies to the specific administration guideline
    "dosingGuideline" : [{ // Guidelines for dosage of the medication
      "treatmentIntent" : { CodeableConcept }, // Intention of the treatment
      "dosage" : [{ // Dosage for the medication for the specific guidelines
        "type" : { CodeableConcept }, // R!  Category of dosage for a medication
        "dosage" : [{ Dosage }] // R!  Dosage for the medication for the specific guidelines
      }],
      "administrationTreatment" : { CodeableConcept }, // Type of treatment the guideline applies to
      "patientCharacteristic" : [{ // Characteristics of the patient that are relevant to the administration guidelines
        "type" : { CodeableConcept }, // R!  Categorization of specific characteristic that is relevant to the administration guideline
        // value[x]: The specific characteristic. One of these 3:
        "valueCodeableConcept" : { CodeableConcept },
        "valueQuantity" : { Quantity },
        "valueRange" : { Range }
      }]
    }]
  }],
  "medicineClassification" : [{ // Categorization of the medication within a formulary or classification system
    "type" : { CodeableConcept }, // R!  The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
    // source[x]: The source of the classification. One of these 2:
    "sourceString" : "<string>",
    "sourceUri" : "<uri>",
    "classification" : [{ CodeableConcept }] // Specific category assigned to the medication
  }],
  "packaging" : [{ // Details about packaged medications
    "cost" : [{ Content as for MedicationKnowledge.cost }], // Cost of the packaged medication
    "packagedProduct" : { Reference(PackagedProductDefinition) } // The packaged medication that is being priced
  }],
  "clinicalUseIssue" : [{ Reference(ClinicalUseDefinition) }], // Potential clinical issue with or between medication(s)
  "storageGuideline" : [{ // How the medication should be stored
    "reference" : "<uri>", // Reference to additional information
    "note" : [{ Annotation }], // Additional storage notes
    "stabilityDuration" : { Duration }, // Duration remains stable
    "environmentalSetting" : [{ // Setting or value of environment for adequate storage
      "type" : { CodeableConcept }, // R!  Categorization of the setting
      // value[x]: Value of the setting. One of these 3:
      "valueQuantity" : { Quantity },
      "valueRange" : { Range },
      "valueCodeableConcept" : { CodeableConcept }
    }]
  }],
  "regulatory" : [{ // Regulatory information about a medication
    "regulatoryAuthority" : { Reference(Organization) }, // R!  Specifies the authority of the regulation
    "substitution" : [{ // Specifies if changes are allowed when dispensing a medication from a regulatory perspective
      "type" : { CodeableConcept }, // R!  Specifies the type of substitution allowed
      "allowed" : <boolean> // R!  Specifies if regulation allows for changes in the medication when dispensing
    }],
    "schedule" : [{ CodeableConcept }], // Specifies the schedule of a medication in jurisdiction
    "maxDispense" : { // The maximum number of units of the medication that can be dispensed in a period
      "quantity" : { Quantity(SimpleQuantity) }, // R!  The maximum number of units of the medication that can be dispensed
      "period" : { Duration } // The period that applies to the maximum number of units
    }
  }],
  "definitional" : { // Minimal definition information about the medication
    "definition" : [{ Reference(MedicinalProductDefinition) }], // Definitional resources that provide more information about this medication
    "doseForm" : { CodeableConcept }, // powder | tablets | capsule +
    "intendedRoute" : [{ CodeableConcept }], // The intended or approved route of administration
    "ingredient" : [{ // Active or inactive ingredient
      "item" : { CodeableReference(Substance) }, // R!  Substances contained in the medication
      "type" : { CodeableConcept }, // A code that defines the type of ingredient, active, base, etc. 
      // strength[x]: Quantity of ingredient present. One of these 3:
      "strengthRatio" : { Ratio },
      "strengthCodeableConcept" : { CodeableConcept },
      "strengthQuantity" : { Quantity }
    }],
    "drugCharacteristic" : [{ // Specifies descriptive properties of the medicine
      "type" : { CodeableConcept }, // Code specifying the type of characteristic of medication
      // value[x]: Description of the characteristic. One of these 5:
      "valueCodeableConcept" : { CodeableConcept },
      "valueString" : "<string>",
      "valueQuantity" : { Quantity(SimpleQuantity) },
      "valueBase64Binary" : "<base64Binary>",
      "valueAttachment" : { Attachment }
    }]
  }
}

@prefix fhir: <http://hl7.org/fhir/> .


[ a fhir:MedicationKnowledge;
  fhir:nodeRole fhir:treeRoot; # if this is the parser root

  # from Resource: .id, .meta, .implicitRules, and .language
  # from DomainResource: .text, .contained, .extension, and .modifierExtension
  fhir:MedicationKnowledge.identifier [ Identifier ], ... ; # 0..* Business identifier for this medication
  fhir:MedicationKnowledge.code [ CodeableConcept ]; # 0..1 Code that identifies this medication
  fhir:MedicationKnowledge.status [ code ]; # 0..1 active | entered-in-error | inactive
  fhir:MedicationKnowledge.author [ Reference(Organization) ]; # 0..1 Creator or owner of the knowledge or information about the medication
  fhir:MedicationKnowledge.intendedJurisdiction [ CodeableConcept ], ... ; # 0..* Codes that identify the different jurisdictions for which the information of this resource was created
  fhir:MedicationKnowledge.name [ string ], ... ; # 0..* A name associated with the medication being described
  fhir:MedicationKnowledge.relatedMedicationKnowledge [ # 0..* Associated or related medication information
    fhir:MedicationKnowledge.relatedMedicationKnowledge.type [ CodeableConcept ]; # 1..1 Category of medicationKnowledge
    fhir:MedicationKnowledge.relatedMedicationKnowledge.reference [ Reference(MedicationKnowledge) ], ... ; # 1..* Associated documentation about the associated medication knowledge
  ], ...;
  fhir:MedicationKnowledge.associatedMedication [ Reference(Medication) ], ... ; # 0..* The set of medication resources that are associated with this medication
  fhir:MedicationKnowledge.productType [ CodeableConcept ], ... ; # 0..* Category of the medication or product
  fhir:MedicationKnowledge.monograph [ # 0..* Associated documentation about the medication
    fhir:MedicationKnowledge.monograph.type [ CodeableConcept ]; # 0..1 The category of medication document
    fhir:MedicationKnowledge.monograph.source [ Reference(DocumentReference) ]; # 0..1 Associated documentation about the medication
  ], ...;
  fhir:MedicationKnowledge.preparationInstruction [ markdown ]; # 0..1 The instructions for preparing the medication
  fhir:MedicationKnowledge.cost [ # 0..* The pricing of the medication
    fhir:MedicationKnowledge.cost.effectiveDate [ Period ], ... ; # 0..* The date range for which the cost is effective
    fhir:MedicationKnowledge.cost.type [ CodeableConcept ]; # 1..1 The category of the cost information
    fhir:MedicationKnowledge.cost.source [ string ]; # 0..1 The source or owner for the price information
    # MedicationKnowledge.cost.cost[x] : 1..1 The price or category of the cost of the medication. One of these 2
      fhir:MedicationKnowledge.cost.costMoney [ Money ]
      fhir:MedicationKnowledge.cost.costCodeableConcept [ CodeableConcept ]
  ], ...;
  fhir:MedicationKnowledge.monitoringProgram [ # 0..* Program under which a medication is reviewed
    fhir:MedicationKnowledge.monitoringProgram.type [ CodeableConcept ]; # 0..1 Type of program under which the medication is monitored
    fhir:MedicationKnowledge.monitoringProgram.name [ string ]; # 0..1 Name of the reviewing program
  ], ...;
  fhir:MedicationKnowledge.indicationGuideline [ # 0..* Guidelines or protocols for administration of the medication for an indication
    fhir:MedicationKnowledge.indicationGuideline.indication [ CodeableReference(ClinicalUseDefinition) ], ... ; # 0..* Indication for use that applies to the specific administration guideline
    fhir:MedicationKnowledge.indicationGuideline.dosingGuideline [ # 0..* Guidelines for dosage of the medication
      fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.treatmentIntent [ CodeableConcept ]; # 0..1 Intention of the treatment
      fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.dosage [ # 0..* Dosage for the medication for the specific guidelines
        fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.dosage.type [ CodeableConcept ]; # 1..1 Category of dosage for a medication
        fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.dosage.dosage [ Dosage ], ... ; # 1..* Dosage for the medication for the specific guidelines
      ], ...;
      fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.administrationTreatment [ CodeableConcept ]; # 0..1 Type of treatment the guideline applies to
      fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic [ # 0..* Characteristics of the patient that are relevant to the administration guidelines
        fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.type [ CodeableConcept ]; # 1..1 Categorization of specific characteristic that is relevant to the administration guideline
        # MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.value[x] : 0..1 The specific characteristic. One of these 3
          fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.valueCodeableConcept [ CodeableConcept ]
          fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.valueQuantity [ Quantity ]
          fhir:MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.valueRange [ Range ]
      ], ...;
    ], ...;
  ], ...;
  fhir:MedicationKnowledge.medicineClassification [ # 0..* Categorization of the medication within a formulary or classification system
    fhir:MedicationKnowledge.medicineClassification.type [ CodeableConcept ]; # 1..1 The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)
    # MedicationKnowledge.medicineClassification.source[x] : 0..1 The source of the classification. One of these 2
      fhir:MedicationKnowledge.medicineClassification.sourceString [ string ]
      fhir:MedicationKnowledge.medicineClassification.sourceUri [ uri ]
    fhir:MedicationKnowledge.medicineClassification.classification [ CodeableConcept ], ... ; # 0..* Specific category assigned to the medication
  ], ...;
  fhir:MedicationKnowledge.packaging [ # 0..* Details about packaged medications
    fhir:MedicationKnowledge.packaging.cost [ See MedicationKnowledge.cost ], ... ; # 0..* Cost of the packaged medication
    fhir:MedicationKnowledge.packaging.packagedProduct [ Reference(PackagedProductDefinition) ]; # 0..1 The packaged medication that is being priced
  ], ...;
  fhir:MedicationKnowledge.clinicalUseIssue [ Reference(ClinicalUseDefinition) ], ... ; # 0..* Potential clinical issue with or between medication(s)
  fhir:MedicationKnowledge.storageGuideline [ # 0..* How the medication should be stored
    fhir:MedicationKnowledge.storageGuideline.reference [ uri ]; # 0..1 Reference to additional information
    fhir:MedicationKnowledge.storageGuideline.note [ Annotation ], ... ; # 0..* Additional storage notes
    fhir:MedicationKnowledge.storageGuideline.stabilityDuration [ Duration ]; # 0..1 Duration remains stable
    fhir:MedicationKnowledge.storageGuideline.environmentalSetting [ # 0..* Setting or value of environment for adequate storage
      fhir:MedicationKnowledge.storageGuideline.environmentalSetting.type [ CodeableConcept ]; # 1..1 Categorization of the setting
      # MedicationKnowledge.storageGuideline.environmentalSetting.value[x] : 1..1 Value of the setting. One of these 3
        fhir:MedicationKnowledge.storageGuideline.environmentalSetting.valueQuantity [ Quantity ]
        fhir:MedicationKnowledge.storageGuideline.environmentalSetting.valueRange [ Range ]
        fhir:MedicationKnowledge.storageGuideline.environmentalSetting.valueCodeableConcept [ CodeableConcept ]
    ], ...;
  ], ...;
  fhir:MedicationKnowledge.regulatory [ # 0..* Regulatory information about a medication
    fhir:MedicationKnowledge.regulatory.regulatoryAuthority [ Reference(Organization) ]; # 1..1 Specifies the authority of the regulation
    fhir:MedicationKnowledge.regulatory.substitution [ # 0..* Specifies if changes are allowed when dispensing a medication from a regulatory perspective
      fhir:MedicationKnowledge.regulatory.substitution.type [ CodeableConcept ]; # 1..1 Specifies the type of substitution allowed
      fhir:MedicationKnowledge.regulatory.substitution.allowed [ boolean ]; # 1..1 Specifies if regulation allows for changes in the medication when dispensing
    ], ...;
    fhir:MedicationKnowledge.regulatory.schedule [ CodeableConcept ], ... ; # 0..* Specifies the schedule of a medication in jurisdiction
    fhir:MedicationKnowledge.regulatory.maxDispense [ # 0..1 The maximum number of units of the medication that can be dispensed in a period
      fhir:MedicationKnowledge.regulatory.maxDispense.quantity [ Quantity(SimpleQuantity) ]; # 1..1 The maximum number of units of the medication that can be dispensed
      fhir:MedicationKnowledge.regulatory.maxDispense.period [ Duration ]; # 0..1 The period that applies to the maximum number of units
    ];
  ], ...;
  fhir:MedicationKnowledge.definitional [ # 0..1 Minimal definition information about the medication
    fhir:MedicationKnowledge.definitional.definition [ Reference(MedicinalProductDefinition) ], ... ; # 0..* Definitional resources that provide more information about this medication
    fhir:MedicationKnowledge.definitional.doseForm [ CodeableConcept ]; # 0..1 powder | tablets | capsule +
    fhir:MedicationKnowledge.definitional.intendedRoute [ CodeableConcept ], ... ; # 0..* The intended or approved route of administration
    fhir:MedicationKnowledge.definitional.ingredient [ # 0..* Active or inactive ingredient
      fhir:MedicationKnowledge.definitional.ingredient.item [ CodeableReference(Substance) ]; # 1..1 Substances contained in the medication
      fhir:MedicationKnowledge.definitional.ingredient.type [ CodeableConcept ]; # 0..1 A code that defines the type of ingredient, active, base, etc.
      # MedicationKnowledge.definitional.ingredient.strength[x] : 0..1 Quantity of ingredient present. One of these 3
        fhir:MedicationKnowledge.definitional.ingredient.strengthRatio [ Ratio ]
        fhir:MedicationKnowledge.definitional.ingredient.strengthCodeableConcept [ CodeableConcept ]
        fhir:MedicationKnowledge.definitional.ingredient.strengthQuantity [ Quantity ]
    ], ...;
    fhir:MedicationKnowledge.definitional.drugCharacteristic [ # 0..* Specifies descriptive properties of the medicine
      fhir:MedicationKnowledge.definitional.drugCharacteristic.type [ CodeableConcept ]; # 0..1 Code specifying the type of characteristic of medication
      # MedicationKnowledge.definitional.drugCharacteristic.value[x] : 0..1 Description of the characteristic. One of these 5
        fhir:MedicationKnowledge.definitional.drugCharacteristic.valueCodeableConcept [ CodeableConcept ]
        fhir:MedicationKnowledge.definitional.drugCharacteristic.valueString [ string ]
        fhir:MedicationKnowledge.definitional.drugCharacteristic.valueSimpleQuantity [ Quantity(SimpleQuantity) ]
        fhir:MedicationKnowledge.definitional.drugCharacteristic.valueBase64Binary [ base64Binary ]
        fhir:MedicationKnowledge.definitional.drugCharacteristic.valueAttachment [ Attachment ]
    ], ...;
  ];
]

See the Full Difference for further information

This analysis is available as XML or JSON.