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Clinical Decision Support Work Group | Maturity Level: N/A | Standards Status: Informative | Compartments: Not linked to any defined compartments |
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Risk of fatal ICH without alteplase for stroke
@prefix fhir: <http://hl7.org/fhir/> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- [a fhir:Evidence; fhir:nodeRole fhir:treeRoot; fhir:Resource.id [ fhir:value "example-stroke-no-alteplase-fatalICH"]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\">\n <p>\n "Risk of fatal ICH without alteplase for stroke" is a univariate risk estimate.\n </p>\n </div>" ]; fhir:Evidence.url [ fhir:value "http://hl7.org/fhir/Evidence/example-stroke-no-alteplase-fatalICH"]; fhir:Evidence.identifier [ fhir:index 0; fhir:Identifier.system [ fhir:value "urn:ietf:rfc:3986" ]; fhir:Identifier.value [ fhir:value "urn:oid:2.16.840.1.113883.4.642.10.4" ] ]; fhir:Evidence.title [ fhir:value "Risk of fatal ICH without alteplase for stroke"]; fhir:Evidence.status [ fhir:value "draft"]; fhir:Evidence.relatedArtifact [ fhir:index 0; fhir:RelatedArtifact.type [ fhir:value "citation" ]; fhir:RelatedArtifact.label [ fhir:value "Emberson 2014" ]; fhir:RelatedArtifact.display [ fhir:value "Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials." ]; fhir:RelatedArtifact.citation [ fhir:value "Emberson J, Lees KR, Lyden P, Blackwell L, Albers G, Bluhmki E, et al;Stroke Thrombolysis Trialists' Collaborative Group. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet 2014 Nov 29;384(9958):1929-35 PMID 25106063" ]; fhir:RelatedArtifact.document [ fhir:Attachment.url [ fhir:value "https://doi.org/10.1016/S0140-6736(14)60584-5" ] ] ]; fhir:Evidence.description [ fhir:value "0.4% incidence of fatal intracranial hemorrhage within 7 days without alteplase in patients with acute ischemic stroke"]; fhir:Evidence.variableDefinition [ fhir:index 0; fhir:Evidence.variableDefinition.variableRole [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/variable-role" ]; fhir:Coding.code [ fhir:value "population" ]; fhir:Coding.display [ fhir:value "population" ] ] ]; fhir:Evidence.variableDefinition.observed [ fhir:Reference.reference [ fhir:value "Group/AcuteIschemicStroke" ]; fhir:Reference.type [ fhir:value "Group" ]; fhir:Reference.display [ fhir:value "adults with acute ischemic stroke" ] ]; fhir:Evidence.variableDefinition.intended [ fhir:Reference.reference [ fhir:value "Group/AcuteIschemicStroke" ]; fhir:Reference.type [ fhir:value "Group" ]; fhir:Reference.display [ fhir:value "adults with acute ischemic stroke" ] ] ], [ fhir:index 1; fhir:Evidence.variableDefinition.variableRole [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/variable-role" ]; fhir:Coding.code [ fhir:value "population" ]; fhir:Coding.display [ fhir:value "population" ] ] ]; fhir:Evidence.variableDefinition.observed [ fhir:Reference.reference [ fhir:value "Group/Emberson-2014-IPD-MA-No-Alteplase-Cohort" ]; fhir:Reference.type [ fhir:value "Group" ]; fhir:Reference.display [ fhir:value "Emberson 2014 IPD-MA No Alteplase Cohort" ] ]; fhir:Evidence.variableDefinition.intended [ fhir:Reference.reference [ fhir:value "Group/AcuteIschemicStrokeTreatedWithoutAlteplase" ]; fhir:Reference.type [ fhir:value "Group" ]; fhir:Reference.display [ fhir:value "adults with acute ischemic stroke treated without alteplase" ] ] ], [ fhir:index 2; fhir:Evidence.variableDefinition.variableRole [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/variable-role" ]; fhir:Coding.code [ fhir:value "measuredVariable" ]; fhir:Coding.display [ fhir:value "measured variable" ] ] ]; fhir:Evidence.variableDefinition.observed [ fhir:Reference.reference [ fhir:value "EvidenceVariable/example-fatal-ICH-in-7-days" ]; fhir:Reference.type [ fhir:value "EvidenceVariable" ]; fhir:Reference.display [ fhir:value "fatal ICH" ] ]; fhir:Evidence.variableDefinition.intended [ fhir:Reference.reference [ fhir:value "EvidenceVariable/example-fatal-ICH-in-7-days" ]; fhir:Reference.type [ fhir:value "EvidenceVariable" ]; fhir:Reference.display [ fhir:value "fatal ICH" ] ] ]; fhir:Evidence.synthesisType [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/synthesis-type" ]; fhir:Coding.code [ fhir:value "IPD-MA" ]; fhir:Coding.display [ fhir:value "individual patient data meta-analysis" ] ] ]; fhir:Evidence.studyDesign [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://hl7.org/fhir/research-study-classifiers" ]; fhir:Coding.code [ fhir:value "SEVCO:01003" ]; fhir:Coding.display [ fhir:value "randomized assignment" ] ] ]; fhir:Evidence.statistic [ fhir:index 0; fhir:Evidence.statistic.statisticType [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/statistic-type" ]; fhir:Coding.code [ fhir:value "C44256" ]; fhir:Coding.display [ fhir:value "Proportion" ] ] ]; fhir:Evidence.statistic.quantity [ fhir:Quantity.value [ fhir:value "0.00386298627"^^xsd:decimal ] ]; fhir:Evidence.statistic.numberOfEvents [ fhir:value "13"^^xsd:nonNegativeInteger ]; fhir:Evidence.statistic.sampleSize [ fhir:Evidence.statistic.sampleSize.numberOfStudies [ fhir:value "9"^^xsd:nonNegativeInteger ]; fhir:Evidence.statistic.sampleSize.numberOfParticipants [ fhir:value "3365"^^xsd:nonNegativeInteger ] ] ]] . # - ontology header ------------------------------------------------------------ [a owl:Ontology; owl:imports fhir:fhir.ttl] . # -------------------------------------------------------------------------------------
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.
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