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Clinical Decision Support Work Group | Maturity Level: N/A | Standards Status: Informative | Compartments: Not linked to any defined compartments |
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Certainty Rating of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19
@prefix fhir: <http://hl7.org/fhir/> . @prefix owl: <http://www.w3.org/2002/07/owl#> . @prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> . @prefix xsd: <http://www.w3.org/2001/XMLSchema#> . # - resource ------------------------------------------------------------------- [a fhir:ArtifactAssessment; fhir:nodeRole fhir:treeRoot; fhir:Resource.id [ fhir:value "example-certainty-rating"]; fhir:DomainResource.text [ fhir:Narrative.status [ fhir:value "generated" ]; fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative: ArtifactAssessment</b><a name=\"example-certainty-rating\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">Resource ArtifactAssessment "example-certainty-rating" </p></div><p><b>identifier</b>: FEvIR Object Identifier: 27756</p><p><b>date</b>: 2021-11-02T14:48:59.89Z</p><p><b>copyright</b>: https://creativecommons.org/licenses/by-nc-sa/4.0/</p><p><b>artifact</b>: <a href=\"broken-link.html\">Evidence/18812: Critically appraised summary of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19</a></p><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>summary</b>: serious concerns with risk of bias, inconsistency, and imprecision</p><p><b>type</b>: Overall certainty <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#Overall)</span></p><p><b>classifier</b>: Very low quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#very-low)</span></p><p><b>author</b>: <span>: Brian S. Alper</span></p><p><b>freeToShare</b>: true</p><h3>Components</h3><table class=\"grid\"><tr><td>-</td><td><b>InformationType</b></td><td><b>Summary</b></td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>Author</b></td></tr><tr><td>*</td><td>rating</td><td>risk of bias in both included trials</td><td>Risk of bias <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#RiskOfBias)</span></td><td>serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#serious-concern)</span></td><td><span>: Brian S. Alper</span></td></tr><tr><td>*</td><td>rating</td><td>high degree of heterogeneity (I-squared 80.7%) with confidence intervals of 2 trial effect estimates barely overlapping</td><td>Inconsistency <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#Inconsistency)</span></td><td>serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#serious-concern)</span></td><td><span>: Brian S. Alper</span></td></tr><tr><td>*</td><td>rating</td><td> </td><td>Indirectness <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#Indirectness)</span></td><td>no serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#no-concern)</span></td><td><span>: Brian S. Alper</span></td></tr><tr><td>*</td><td>rating</td><td>95% confidence interval includes both large effects and no effects</td><td>Imprecision <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#Imprecision)</span></td><td>serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#serious-concern)</span></td><td><span>: Brian S. Alper</span></td></tr><tr><td>*</td><td>rating</td><td> </td><td>Publication bias <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-type.html\">EvidenceCertaintyType</a>#PublicationBias)</span></td><td>no serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"codesystem-certainty-rating.html\">EvidenceCertaintyRating</a>#no-concern)</span></td><td><span>: Brian S. Alper</span></td></tr></table></blockquote></div>" ]; fhir:ArtifactAssessment.identifier [ fhir:index 0; fhir:Identifier.type [ fhir:CodeableConcept.text [ fhir:value "FEvIR Object Identifier" ] ]; fhir:Identifier.system [ fhir:value "https://fevir.net" ]; fhir:Identifier.value [ fhir:value "27756" ]; fhir:Identifier.assigner [ fhir:Reference.display [ fhir:value "Computable Publishing LLC" ] ] ]; fhir:ArtifactAssessment.date [ fhir:value "2021-11-02T14:48:59.890Z"^^xsd:dateTime]; fhir:ArtifactAssessment.copyright [ fhir:value "https://creativecommons.org/licenses/by-nc-sa/4.0/"]; fhir:ArtifactAssessment.artifactReference [ fhir:Reference.reference [ fhir:value "Evidence/18812" ]; fhir:Reference.type [ fhir:value "Evidence" ]; fhir:Reference.display [ fhir:value "Critically appraised summary of all-cause mortality in meta-analysis of RCTs of heparin for moderately ill patients with COVID-19" ] ]; fhir:ArtifactAssessment.content [ fhir:index 0; fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ]; fhir:ArtifactAssessment.content.summary [ fhir:value "serious concerns with risk of bias, inconsistency, and imprecision" ]; fhir:ArtifactAssessment.content.type [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-type" ]; fhir:Coding.code [ fhir:value "Overall" ]; fhir:Coding.display [ fhir:value "Overall certainty" ] ] ]; fhir:ArtifactAssessment.content.classifier [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-rating" ]; fhir:Coding.code [ fhir:value "very-low" ]; fhir:Coding.display [ fhir:value "Very low quality" ] ] ]; fhir:ArtifactAssessment.content.author [ fhir:Reference.display [ fhir:value "Brian S. Alper" ] ]; fhir:ArtifactAssessment.content.freeToShare [ fhir:value "true"^^xsd:boolean ]; fhir:ArtifactAssessment.content.component [ fhir:index 0; fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ]; fhir:ArtifactAssessment.content.summary [ fhir:value "risk of bias in both included trials" ]; fhir:ArtifactAssessment.content.type [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-type" ]; fhir:Coding.code [ fhir:value "RiskOfBias" ]; fhir:Coding.display [ fhir:value "Risk of bias" ] ] ]; fhir:ArtifactAssessment.content.classifier [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-rating" ]; fhir:Coding.code [ fhir:value "serious-concern" ]; fhir:Coding.display [ fhir:value "serious concern" ] ] ]; fhir:ArtifactAssessment.content.author [ fhir:Reference.display [ fhir:value "Brian S. Alper" ] ] ], [ fhir:index 1; fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ]; fhir:ArtifactAssessment.content.summary [ fhir:value "high degree of heterogeneity (I-squared 80.7%) with confidence intervals of 2 trial effect estimates barely overlapping" ]; fhir:ArtifactAssessment.content.type [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-type" ]; fhir:Coding.code [ fhir:value "Inconsistency" ]; fhir:Coding.display [ fhir:value "Inconsistency" ] ] ]; fhir:ArtifactAssessment.content.classifier [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-rating" ]; fhir:Coding.code [ fhir:value "serious-concern" ]; fhir:Coding.display [ fhir:value "serious concern" ] ] ]; fhir:ArtifactAssessment.content.author [ fhir:Reference.display [ fhir:value "Brian S. Alper" ] ] ], [ fhir:index 2; fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ]; fhir:ArtifactAssessment.content.type [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-type" ]; fhir:Coding.code [ fhir:value "Indirectness" ]; fhir:Coding.display [ fhir:value "Indirectness" ] ] ]; fhir:ArtifactAssessment.content.classifier [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-rating" ]; fhir:Coding.code [ fhir:value "no-concern" ]; fhir:Coding.display [ fhir:value "no serious concern" ] ] ]; fhir:ArtifactAssessment.content.author [ fhir:Reference.display [ fhir:value "Brian S. Alper" ] ] ], [ fhir:index 3; fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ]; fhir:ArtifactAssessment.content.summary [ fhir:value "95% confidence interval includes both large effects and no effects" ]; fhir:ArtifactAssessment.content.type [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-type" ]; fhir:Coding.code [ fhir:value "Imprecision" ]; fhir:Coding.display [ fhir:value "Imprecision" ] ] ]; fhir:ArtifactAssessment.content.classifier [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-rating" ]; fhir:Coding.code [ fhir:value "serious-concern" ]; fhir:Coding.display [ fhir:value "serious concern" ] ] ]; fhir:ArtifactAssessment.content.author [ fhir:Reference.display [ fhir:value "Brian S. Alper" ] ] ], [ fhir:index 4; fhir:ArtifactAssessment.content.informationType [ fhir:value "rating" ]; fhir:ArtifactAssessment.content.type [ fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-type" ]; fhir:Coding.code [ fhir:value "PublicationBias" ]; fhir:Coding.display [ fhir:value "Publication bias" ] ] ]; fhir:ArtifactAssessment.content.classifier [ fhir:index 0; fhir:CodeableConcept.coding [ fhir:index 0; fhir:Coding.system [ fhir:value "http://terminology.hl7.org/CodeSystem/certainty-rating" ]; fhir:Coding.code [ fhir:value "no-concern" ]; fhir:Coding.display [ fhir:value "no serious concern" ] ] ]; fhir:ArtifactAssessment.content.author [ fhir:Reference.display [ fhir:value "Brian S. Alper" ] ] ] ]] . # - ontology header ------------------------------------------------------------ [a owl:Ontology; owl:imports fhir:fhir.ttl] . # -------------------------------------------------------------------------------------
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.
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