Release 5 Draft Ballot

This page is part of the FHIR Specification (v4.6.0: R5 Draft Ballot). The current version which supercedes this version is 5.0.0. For a full list of available versions, see the Directory of published versions . Page versions: R5 R4B R4

Medicationknowledge.profile.json

Pharmacy Work GroupMaturity Level: N/AStandards Status: InformativeCompartments: Not linked to any defined compartments

Raw JSON (canonical form + also see JSON Format Specification)

StructureDefinition for medicationknowledge

{
  "resourceType" : "StructureDefinition",
  "id" : "MedicationKnowledge",
  "meta" : {
    "lastUpdated" : "2021-04-15T12:25:09.461+10:00"
  },
  "text" : {
    "status" : "generated",
    "div" : "<div>!-- Snipped for Brevity --></div>"
  },
  "extension" : [{
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-category",
    "valueString" : "Clinical.Medications"
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
    "valueCode" : "trial-use"
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
    "valueInteger" : 1
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-security-category",
    "valueCode" : "business"
  },
  {
    "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
    "valueCode" : "phx"
  }],
  "url" : "http://hl7.org/fhir/StructureDefinition/MedicationKnowledge",
  "version" : "4.6.0",
  "name" : "MedicationKnowledge",
  "status" : "draft",
  "date" : "2021-04-15T12:25:09+10:00",
  "publisher" : "Health Level Seven International (Pharmacy)",
  "contact" : [{
    "telecom" : [{
      "system" : "url",
      "value" : "http://hl7.org/fhir"
    }]
  },
  {
    "telecom" : [{
      "system" : "url",
      "value" : "http://www.hl7.org/Special/committees/medication/index.cfm"
    }]
  }],
  "description" : "Information about a medication that is used to support knowledge.",
  "fhirVersion" : "4.6.0",
  "mapping" : [{
    "identity" : "w5",
    "uri" : "http://hl7.org/fhir/fivews",
    "name" : "FiveWs Pattern Mapping"
  },
  {
    "identity" : "script10.6",
    "uri" : "http://ncpdp.org/SCRIPT10_6",
    "name" : "Mapping to NCPDP SCRIPT 10.6"
  },
  {
    "identity" : "v2",
    "uri" : "http://hl7.org/v2",
    "name" : "HL7 v2 Mapping"
  },
  {
    "identity" : "rim",
    "uri" : "http://hl7.org/v3",
    "name" : "RIM Mapping"
  }],
  "kind" : "resource",
  "abstract" : false,
  "type" : "MedicationKnowledge",
  "baseDefinition" : "http://hl7.org/fhir/StructureDefinition/DomainResource",
  "derivation" : "specialization",
  "snapshot" : {
    "element" : [{
      "id" : "MedicationKnowledge",
      "path" : "MedicationKnowledge",
      "short" : "Definition of Medication Knowledge",
      "definition" : "Information about a medication that is used to support knowledge.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge",
        "min" : 0,
        "max" : "*"
      },
      "constraint" : [{
        "key" : "dom-2",
        "severity" : "error",
        "human" : "If the resource is contained in another resource, it SHALL NOT contain nested Resources",
        "expression" : "contained.contained.empty()",
        "xpath" : "not(parent::f:contained and f:contained)",
        "source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
      },
      {
        "key" : "dom-3",
        "severity" : "error",
        "human" : "If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource",
        "expression" : "contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()",
        "xpath" : "not(exists(for $id in f:contained/*/f:id/@value return $contained[not(parent::*/descendant::f:reference/@value=concat('#', $contained/*/id/@value) or descendant::f:reference[@value='#'])]))",
        "source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
      },
      {
        "key" : "dom-4",
        "severity" : "error",
        "human" : "If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated",
        "expression" : "contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()",
        "xpath" : "not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))",
        "source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
      },
      {
        "key" : "dom-5",
        "severity" : "error",
        "human" : "If a resource is contained in another resource, it SHALL NOT have a security label",
        "expression" : "contained.meta.security.empty()",
        "xpath" : "not(exists(f:contained/*/f:meta/f:security))",
        "source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
      },
      {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice",
          "valueBoolean" : true
        },
        {
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bestpractice-explanation",
          "valueMarkdown" : "When a resource has no narrative, only systems that fully understand the data can display the resource to a human safely. Including a human readable representation in the resource makes for a much more robust eco-system and cheaper handling of resources by intermediary systems. Some ecosystems restrict distribution of resources to only those systems that do fully understand the resources, and as a consequence implementers may believe that the narrative is superfluous. However experience shows that such eco-systems often open up to new participants over time."
        }],
        "key" : "dom-6",
        "severity" : "warning",
        "human" : "A resource should have narrative for robust management",
        "expression" : "text.`div`.exists()",
        "xpath" : "exists(f:text/h:div)",
        "source" : "http://hl7.org/fhir/StructureDefinition/DomainResource"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "Entity. Role, or Act"
      },
      {
        "identity" : "w5",
        "map" : "administrative.medication"
      }]
    },
    {
      "id" : "MedicationKnowledge.id",
      "path" : "MedicationKnowledge.id",
      "short" : "Logical id of this artifact",
      "definition" : "The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.",
      "comment" : "Typically, the resource has an id except for cases like the create operation, conditional updates.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Resource.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.meta",
      "path" : "MedicationKnowledge.meta",
      "short" : "Metadata about the resource",
      "definition" : "The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Resource.meta",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Meta"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.implicitRules",
      "path" : "MedicationKnowledge.implicitRules",
      "short" : "A set of rules under which this content was created",
      "definition" : "A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.",
      "comment" : "Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of it's narrative along with other profiles, value sets, etc.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Resource.implicitRules",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "uri"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : true,
      "isModifierReason" : "This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it's meaning or interpretation",
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.language",
      "path" : "MedicationKnowledge.language",
      "short" : "Language of the resource content",
      "definition" : "The base language in which the resource is written.",
      "comment" : "Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies  to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Resource.language",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "code"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/build/StructureDefinition/definition",
          "valueString" : "A human language."
        },
        {
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet",
          "valueCanonical" : "http://hl7.org/fhir/ValueSet/all-languages"
        },
        {
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "Language"
        },
        {
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding",
          "valueBoolean" : true
        }],
        "strength" : "preferred",
        "description" : "IETF language tag",
        "valueSet" : "http://hl7.org/fhir/ValueSet/languages"
      }
    },
    {
      "id" : "MedicationKnowledge.text",
      "path" : "MedicationKnowledge.text",
      "short" : "Text summary of the resource, for human interpretation",
      "definition" : "A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it \"clinically safe\" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.",
      "comment" : "Contained resources do not have a narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied).  This may be necessary for data from legacy systems where information is captured as a \"text blob\" or where text is additionally entered raw or narrated and encoded information is added later.",
      "alias" : ["narrative",
      "html",
      "xhtml",
      "display"],
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "DomainResource.text",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Narrative"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "Act.text?"
      }]
    },
    {
      "id" : "MedicationKnowledge.contained",
      "path" : "MedicationKnowledge.contained",
      "short" : "Contained, inline Resources",
      "definition" : "These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope.",
      "comment" : "This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags In their meta elements, but SHALL NOT have security labels.",
      "alias" : ["inline resources",
      "anonymous resources",
      "contained resources"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "DomainResource.contained",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Resource"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.extension",
      "path" : "MedicationKnowledge.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "DomainResource.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.modifierExtension",
      "path" : "MedicationKnowledge.modifierExtension",
      "short" : "Extensions that cannot be ignored",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "DomainResource.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "mustSupport" : false,
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them",
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.identifier",
      "path" : "MedicationKnowledge.identifier",
      "short" : "Business identifier for this medication",
      "definition" : "Business identifier for this medication.",
      "comment" : "This is a business identifier, not a resource identifier (see discussion).",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.identifier",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Identifier"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.code",
      "path" : "MedicationKnowledge.code",
      "short" : "Code that identifies this medication",
      "definition" : "A code that specifies this medication, or a textual description if no code is available. Usage note: This could be a standard medication code such as a code from RxNorm, SNOMED CT, IDMP etc. It could also be a national or local formulary code, optionally with translations to other code systems.",
      "comment" : "Depending on the context of use, the code that was actually selected by the user (prescriber, dispenser, etc.) will have the coding.userSelected set to true.  As described in the coding datatype: \"A coding may be marked as a \"userSelected\" if a user selected the particular coded value in a user interface (e.g. the user selects an item in a pick-list). If a user selected coding exists, it is the preferred choice for performing translations etc. Other codes can only be literal translations to alternative code systems, or codes at a lower level of granularity (e.g. a generic code for a vendor-specific primary one).",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.code",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationFormalRepresentation"
        }],
        "strength" : "example",
        "description" : "A coded concept that defines the type of a medication.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medication-codes"
      },
      "mapping" : [{
        "identity" : "script10.6",
        "map" : "coding.code = //element(*,MedicationType)/DrugCoded/ProductCode\r\rcoding.system = //element(*,MedicationType)/DrugCoded/ProductCodeQualifier\r\rcoding.display = //element(*,MedicationType)/DrugDescription"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.class"
      },
      {
        "identity" : "v2",
        "map" : "RXO-1.1-Requested Give Code.code / RXE-2.1-Give Code.code / RXD-2.1-Dispense/Give Code.code / RXG-4.1-Give Code.code /RXA-5.1-Administered Code.code / RXC-2.1 Component Code"
      },
      {
        "identity" : "rim",
        "map" : ".code"
      }]
    },
    {
      "id" : "MedicationKnowledge.status",
      "path" : "MedicationKnowledge.status",
      "short" : "active | inactive | entered-in-error",
      "definition" : "A code to indicate if the medication is in active use.  The status refers to the validity about the information of the medication and not to its medicinal properties.",
      "comment" : "This status is intended to identify if the medication in a local system is in active use within a drug database or inventory.  For example, a pharmacy system may create a new drug file record for a compounded product \"ABC Hospital Special Cream\" with an active status.  At some point in the future, it may be determined that the drug record was created with an error and the status is changed to \"entered in error\".   This status is not intended to specify if a medication is part of a particular formulary.  It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.status",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "code"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : true,
      "isModifierReason" : "This element changes the interpretation of all descriptive attributes.",
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationKnowledgeStatus"
        }],
        "strength" : "required",
        "description" : "A coded concept defining if the medication is in active use.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medicationknowledge-status|4.6.0"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : ".statusCode"
      }]
    },
    {
      "id" : "MedicationKnowledge.author",
      "path" : "MedicationKnowledge.author",
      "short" : "Creator or owner of the knowledge or information about the medication",
      "definition" : "The creator or owner of the knowledge or information about the medication.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.author",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Organization"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.actor"
      },
      {
        "identity" : "rim",
        "map" : "ManufacturedProduct.subjectOf.DocumentEvent.author"
      }]
    },
    {
      "id" : "MedicationKnowledge.sponsor",
      "path" : "MedicationKnowledge.sponsor",
      "short" : "Organization responsible for manufacturing of the item",
      "definition" : "Describes the details of the manufacturer of the medication product. This is not intended to represent the distributor of a medication product.  Describes the organization that is responsible for the manufacturing of the item and holds the registration to market the product in a jurisdiction. This might not be the company that physically manufactures the product.  May be known as Market Authorization Holder.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.sponsor",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Organization"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.doseForm",
      "path" : "MedicationKnowledge.doseForm",
      "short" : "powder | tablets | capsule +",
      "definition" : "Describes the form of the item.  Powder; tablets; capsule.",
      "comment" : "When Medication is referenced from MedicationRequest, this is the ordered form.  When Medication is referenced within MedicationDispense, this is the dispensed form.  When Medication is referenced within MedicationAdministration, this is administered form.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.doseForm",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationForm"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the form of a medication.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medication-form-codes"
      },
      "mapping" : [{
        "identity" : "script10.6",
        "map" : "coding.code =  //element(*,DrugCodedType)/FormCode\r\rcoding.system = //element(*,DrugCodedType)/FormSourceCode"
      },
      {
        "identity" : "v2",
        "map" : "RXO-5-Requested Dosage Form / RXE-6-Give Dosage Form / RXD-6-Actual Dosage Form / RXG-8-Give Dosage Form / RXA-8-Administered Dosage Form"
      },
      {
        "identity" : "rim",
        "map" : ".formCode"
      }]
    },
    {
      "id" : "MedicationKnowledge.amount",
      "path" : "MedicationKnowledge.amount",
      "short" : "Amount of drug in package",
      "definition" : "Specific amount of the drug in the packaged product.  For example, when specifying a product that has the same strength (For example, Insulin glargine 100 unit per mL solution for injection), this attribute provides additional clarification of the package amount (For example, 3 mL, 10mL, etc.).",
      "comment" : "This is the quantity of medication in a package.  To specify the strength of the medication, the Ingredient.strength attribute is used.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.amount",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : ".quantity"
      }]
    },
    {
      "id" : "MedicationKnowledge.synonym",
      "path" : "MedicationKnowledge.synonym",
      "short" : "Additional names for a medication",
      "definition" : "Additional names for a medication, for example, the name(s) given to a medication in different countries.  For example, acetaminophen and paracetamol or salbutamol and albuterol.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.synonym",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "string"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.relatedMedicationKnowledge",
      "path" : "MedicationKnowledge.relatedMedicationKnowledge",
      "short" : "Associated or related medication information",
      "definition" : "Associated or related medications. For example, if the medication is a branded product (e.g. Crestor), this is the Therapeutic Moeity (e.g. Rosuvastatin) or if this is a generic medication (e.g. Rosuvastatin), this would link to a branded product (e.g. Crestor.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.relatedMedicationKnowledge",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.relatedMedicationKnowledge.id",
      "path" : "MedicationKnowledge.relatedMedicationKnowledge.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.relatedMedicationKnowledge.extension",
      "path" : "MedicationKnowledge.relatedMedicationKnowledge.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.relatedMedicationKnowledge.modifierExtension",
      "path" : "MedicationKnowledge.relatedMedicationKnowledge.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.relatedMedicationKnowledge.type",
      "path" : "MedicationKnowledge.relatedMedicationKnowledge.type",
      "short" : "Category of medicationKnowledge",
      "definition" : "The category of the associated medication knowledge reference.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.relatedMedicationKnowledge.type",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.relatedMedicationKnowledge.reference",
      "path" : "MedicationKnowledge.relatedMedicationKnowledge.reference",
      "short" : "Associated documentation about the associated medication knowledge",
      "definition" : "Associated documentation about the associated medication knowledge.",
      "min" : 1,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.relatedMedicationKnowledge.reference",
        "min" : 1,
        "max" : "*"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/MedicationKnowledge"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.associatedMedication",
      "path" : "MedicationKnowledge.associatedMedication",
      "short" : "A medication resource that is associated with this medication",
      "definition" : "Links to associated medications that could be prescribed, dispensed or administered.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.associatedMedication",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Medication"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.associatedDefinition",
      "path" : "MedicationKnowledge.associatedDefinition",
      "short" : "A definition resource that is associated with this medication",
      "definition" : "Associated definitions for this medication.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.associatedDefinition",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.productType",
      "path" : "MedicationKnowledge.productType",
      "short" : "Category of the medication or product",
      "definition" : "Category of the medication or product (e.g. branded product, therapeutic moeity, generic product, innovator product, etc.).",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.productType",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.monograph",
      "path" : "MedicationKnowledge.monograph",
      "short" : "Associated documentation about the medication",
      "definition" : "Associated documentation about the medication.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.monograph",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.monograph.id",
      "path" : "MedicationKnowledge.monograph.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.monograph.extension",
      "path" : "MedicationKnowledge.monograph.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.monograph.modifierExtension",
      "path" : "MedicationKnowledge.monograph.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.monograph.type",
      "path" : "MedicationKnowledge.monograph.type",
      "short" : "The category of medication document",
      "definition" : "The category of documentation about the medication. (e.g. professional monograph, patient education monograph).",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.monograph.type",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.monograph.source",
      "path" : "MedicationKnowledge.monograph.source",
      "short" : "Associated documentation about the medication",
      "definition" : "Associated documentation about the medication.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.monograph.source",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/DocumentReference"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.ingredient",
      "path" : "MedicationKnowledge.ingredient",
      "short" : "Active or inactive ingredient",
      "definition" : "Identifies a particular constituent of interest in the product.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.ingredient",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.ingredient.id",
      "path" : "MedicationKnowledge.ingredient.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.ingredient.extension",
      "path" : "MedicationKnowledge.ingredient.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.ingredient.modifierExtension",
      "path" : "MedicationKnowledge.ingredient.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.ingredient.item",
      "path" : "MedicationKnowledge.ingredient.item",
      "short" : "Medication(s) or MedicinalProductIngredient(s) contained in the medication",
      "definition" : "The actual ingredient - either a substance (simple ingredient) or another medication.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.ingredient.item",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableReference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Ingredient"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "script10.6",
        "map" : "coding.code = //element(*,MedicationType)/DrugCoded/ProductCode\r\rcoding.system = //element(*,MedicationType)/DrugCoded/ProductCodeQualifier\r\rcoding.display = //element(*,MedicationType)/DrugDescription"
      },
      {
        "identity" : "v2",
        "map" : "RXC-2-Component Code  if medication: RXO-1-Requested Give Code / RXE-2-Give Code / RXD-2-Dispense/Give Code / RXG-4-Give Code / RXA-5-Administered Code"
      },
      {
        "identity" : "rim",
        "map" : ".player"
      }]
    },
    {
      "id" : "MedicationKnowledge.ingredient.isActive",
      "path" : "MedicationKnowledge.ingredient.isActive",
      "short" : "Active ingredient indicator",
      "definition" : "Indication of whether this ingredient affects the therapeutic action of the drug.",
      "requirements" : "True indicates that the ingredient affects the therapeutic action of the drug (i.e. active). \rFalse indicates that the ingredient does not affect the therapeutic action of the drug (i.e. inactive).",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.ingredient.isActive",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationIngredientIsActive"
        }],
        "strength" : "example",
        "valueSet" : "http://terminology.hl7.org/ValueSet/v3-RoleClassIngredientEntity"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : "NA"
      }]
    },
    {
      "id" : "MedicationKnowledge.ingredient.strength[x]",
      "path" : "MedicationKnowledge.ingredient.strength[x]",
      "short" : "Quantity of ingredient present",
      "definition" : "Specifies how many (or how much) of the items there are in this Medication.  For example, 250 mg per tablet.  This is expressed as a ratio where the numerator is 250mg and the denominator is 1 tablet but can also be expressed a quantity when the denominator is assumed to be 1 tablet.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.ingredient.strength[x]",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Ratio"
      },
      {
        "code" : "CodeableConcept"
      },
      {
        "code" : "Quantity"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationIngredientStrength"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the strength of an ingredient.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medication-ingredientstrength"
      },
      "mapping" : [{
        "identity" : "script10.6",
        "map" : "//element(*,DrugCodedType)/Strength"
      },
      {
        "identity" : "v2",
        "map" : "RXC-3-Component Amount & RXC-4-Component Units  if medication: RXO-2-Requested Give Amount - Minimum & RXO-4-Requested Give Units / RXO-3-Requested Give Amount - Maximum & RXO-4-Requested Give Units / RXO-11-Requested Dispense Amount & RXO-12-Requested Dispense Units / RXE-3-Give Amount - Minimum & RXE-5-Give Units / RXE-4-Give Amount - Maximum & RXE-5-Give Units / RXE-10-Dispense Amount & RXE-10-Dispense Units"
      },
      {
        "identity" : "rim",
        "map" : ".quantity"
      }]
    },
    {
      "id" : "MedicationKnowledge.device",
      "path" : "MedicationKnowledge.device",
      "short" : "A device associated with the medication (for example, a drug coated catheter or a drug impregnated dressing)",
      "definition" : "A device associated with the medication (for example, a drug coated catheter or a drug impregnated dressing).",
      "requirements" : "This attribute should only be populated for those devices that have the drug incorporated in them.  If a device used to administer a medication, for example an applicator or a syringe, needs to be specified, use MedicationKnowledge.packaging.device.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.device",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Device"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.preparationInstruction",
      "path" : "MedicationKnowledge.preparationInstruction",
      "short" : "The instructions for preparing the medication",
      "definition" : "The instructions for preparing the medication.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.preparationInstruction",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "markdown"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.intendedRoute",
      "path" : "MedicationKnowledge.intendedRoute",
      "short" : "The intended or approved route of administration",
      "definition" : "The intended or approved route of administration.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.intendedRoute",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationRoute"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the intended route of administration.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/route-codes"
      }
    },
    {
      "id" : "MedicationKnowledge.cost",
      "path" : "MedicationKnowledge.cost",
      "short" : "The pricing of the medication",
      "definition" : "The price of the medication.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.cost",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.cost.id",
      "path" : "MedicationKnowledge.cost.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.cost.extension",
      "path" : "MedicationKnowledge.cost.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.cost.modifierExtension",
      "path" : "MedicationKnowledge.cost.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.cost.effectiveDate",
      "path" : "MedicationKnowledge.cost.effectiveDate",
      "short" : "The date range for which the cost is effective",
      "definition" : "The date range for which the cost information of the medication is effective.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.cost.effectiveDate",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Period"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.cost.type",
      "path" : "MedicationKnowledge.cost.type",
      "short" : "The category of the cost information",
      "definition" : "The category of the cost information.  For example, manufacturers' cost, patient cost, claim reimbursement cost, actual acquisition cost.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.cost.type",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.cost.source",
      "path" : "MedicationKnowledge.cost.source",
      "short" : "The source or owner for the price information",
      "definition" : "The source or owner that assigns the price to the medication.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.cost.source",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.cost.cost[x]",
      "path" : "MedicationKnowledge.cost.cost[x]",
      "short" : "The price or category of the cost of the medication",
      "definition" : "The price or representation of the cost (for example, Band A, Band B or $, $$) of the medication.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.cost.cost[x]",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "Money"
      },
      {
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationCostCategory"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the category of a medication.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medication-cost-category"
      }
    },
    {
      "id" : "MedicationKnowledge.monitoringProgram",
      "path" : "MedicationKnowledge.monitoringProgram",
      "short" : "Program under which a medication is reviewed",
      "definition" : "The program under which the medication is reviewed.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.monitoringProgram",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.monitoringProgram.id",
      "path" : "MedicationKnowledge.monitoringProgram.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.monitoringProgram.extension",
      "path" : "MedicationKnowledge.monitoringProgram.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.monitoringProgram.modifierExtension",
      "path" : "MedicationKnowledge.monitoringProgram.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.monitoringProgram.type",
      "path" : "MedicationKnowledge.monitoringProgram.type",
      "short" : "Type of program under which the medication is monitored",
      "definition" : "Type of program under which the medication is monitored.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.monitoringProgram.type",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.monitoringProgram.name",
      "path" : "MedicationKnowledge.monitoringProgram.name",
      "short" : "Name of the reviewing program",
      "definition" : "Name of the reviewing program.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.monitoringProgram.name",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "string"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline",
      "path" : "MedicationKnowledge.indicationGuideline",
      "short" : "Guidelines or protocols for administration of the medication for an indication",
      "definition" : "Guidelines or protocols that are applicable for the administration of the medication based on indication.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.indicationGuideline",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.id",
      "path" : "MedicationKnowledge.indicationGuideline.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.extension",
      "path" : "MedicationKnowledge.indicationGuideline.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.modifierExtension",
      "path" : "MedicationKnowledge.indicationGuideline.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.indication",
      "path" : "MedicationKnowledge.indicationGuideline.indication",
      "short" : "Indication for use that applies to the specific administration guideline",
      "definition" : "Indication or reason for use of the medication that applies to the specific administration guideline.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.indicationGuideline.indication",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "CodeableReference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/ClinicalUseIssue"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline",
      "short" : "Guidelines for dosage of the medication",
      "definition" : "The guidelines for the dosage of the medication for the indication.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.id",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.extension",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.modifierExtension",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
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    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.treatmentIntent",
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        "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.treatmentIntent",
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    },
    {
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      "id" : "MedicationKnowledge.medicineClassification.modifierExtension",
      "path" : "MedicationKnowledge.medicineClassification.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.medicineClassification.type",
      "path" : "MedicationKnowledge.medicineClassification.type",
      "short" : "The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)",
      "definition" : "The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification).",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.medicineClassification.type",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.medicineClassification.classification",
      "path" : "MedicationKnowledge.medicineClassification.classification",
      "short" : "Specific category assigned to the medication",
      "definition" : "Specific category assigned to the medication (e.g. anti-infective, anti-hypertensive, antibiotic, etc.).",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.medicineClassification.classification",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging",
      "path" : "MedicationKnowledge.packaging",
      "short" : "Details about packaged medications",
      "definition" : "Information that only applies to packages (not products).",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.packaging",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.id",
      "path" : "MedicationKnowledge.packaging.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.packaging.extension",
      "path" : "MedicationKnowledge.packaging.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.packaging.modifierExtension",
      "path" : "MedicationKnowledge.packaging.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.packaging.identifier",
      "path" : "MedicationKnowledge.packaging.identifier",
      "short" : "Business identifier of the packaged medication",
      "definition" : "The business identifier of the packaged medication.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.packaging.identifier",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Identifier"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.cost",
      "path" : "MedicationKnowledge.packaging.cost",
      "short" : "Cost of the packaged medication",
      "definition" : "The cost of the packaged medication.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.packaging.cost",
        "min" : 0,
        "max" : "1"
      },
      "contentReference" : "#MedicationKnowledge.cost",
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.type",
      "path" : "MedicationKnowledge.packaging.type",
      "short" : "A code that defines the specific type of packaging that the medication can be found in",
      "definition" : "A code that defines the specific type of packaging that the medication can be found in (e.g. blister sleeve, tube, bottle).",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.packaging.type",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationPackageType"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the type of packaging of a medication.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medicationknowledge-package-type"
      }
    },
    {
      "id" : "MedicationKnowledge.packaging.quantity",
      "path" : "MedicationKnowledge.packaging.quantity",
      "short" : "The number of product units the package would contain if fully loaded",
      "definition" : "The number of product units the package would contain if fully loaded.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.packaging.quantity",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.device",
      "path" : "MedicationKnowledge.packaging.device",
      "short" : "The device used to administer the medication (e.g. scoop, applicator, syringe)",
      "definition" : "The device used to administer the medication (e.g. scoop, applicator, syringe).",
      "requirements" : "If specifying devices impregnated with medication, use MedicationKnowledge.device.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.packaging.device",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Device"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.material",
      "path" : "MedicationKnowledge.packaging.material",
      "short" : "Material type of the package item",
      "definition" : "Material type of the package item.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.packaging.material",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.packaging",
      "path" : "MedicationKnowledge.packaging.packaging",
      "short" : "Allows packages within packages",
      "definition" : "Allows packages within packages (e.g. blister packages within a box or vials of medications within a box).",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.packaging.packaging",
        "min" : 0,
        "max" : "*"
      },
      "contentReference" : "#MedicationKnowledge.packaging",
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.drugCharacteristic",
      "path" : "MedicationKnowledge.drugCharacteristic",
      "short" : "Specifies descriptive properties of the medicine",
      "definition" : "Specifies descriptive properties of the medicine, such as color, shape, imprints, etc.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.drugCharacteristic",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.drugCharacteristic.id",
      "path" : "MedicationKnowledge.drugCharacteristic.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.drugCharacteristic.extension",
      "path" : "MedicationKnowledge.drugCharacteristic.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.drugCharacteristic.modifierExtension",
      "path" : "MedicationKnowledge.drugCharacteristic.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.drugCharacteristic.type",
      "path" : "MedicationKnowledge.drugCharacteristic.type",
      "short" : "Code specifying the type of characteristic of medication",
      "definition" : "A code specifying which characteristic of the medicine is being described (for example, colour, shape, imprint).",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.drugCharacteristic.type",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationCharacteristic"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the characteristic types of a medication.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medicationknowledge-characteristic"
      }
    },
    {
      "id" : "MedicationKnowledge.drugCharacteristic.value[x]",
      "path" : "MedicationKnowledge.drugCharacteristic.value[x]",
      "short" : "Description of the characteristic",
      "definition" : "Description of the characteristic.",
      "comment" : "The description should be provided as a CodeableConcept, SimpleQuantity or an image.  The description can be a string only when these others are not available.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.drugCharacteristic.value[x]",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      },
      {
        "code" : "string"
      },
      {
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity"]
      },
      {
        "code" : "base64Binary"
      },
      {
        "code" : "Attachment"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.clinicalUseIssue",
      "path" : "MedicationKnowledge.clinicalUseIssue",
      "short" : "Potential clinical issue with or between medication(s)",
      "definition" : "Potential clinical issue with or between medication(s) (for example, drug-drug interaction, drug-disease contraindication, drug-allergy interaction, etc.).",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.clinicalUseIssue",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/ClinicalUseIssue"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory",
      "path" : "MedicationKnowledge.regulatory",
      "short" : "Regulatory information about a medication",
      "definition" : "Regulatory information about a medication.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.regulatory",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.id",
      "path" : "MedicationKnowledge.regulatory.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.regulatory.extension",
      "path" : "MedicationKnowledge.regulatory.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.regulatory.modifierExtension",
      "path" : "MedicationKnowledge.regulatory.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.regulatory.regulatoryAuthority",
      "path" : "MedicationKnowledge.regulatory.regulatoryAuthority",
      "short" : "Specifies the authority of the regulation",
      "definition" : "The authority that is specifying the regulations.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.regulatory.regulatoryAuthority",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Organization"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.substitution",
      "path" : "MedicationKnowledge.regulatory.substitution",
      "short" : "Specifies if changes are allowed when dispensing a medication from a regulatory perspective",
      "definition" : "Specifies if changes are allowed when dispensing a medication from a regulatory perspective.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.regulatory.substitution",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.substitution.id",
      "path" : "MedicationKnowledge.regulatory.substitution.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.regulatory.substitution.extension",
      "path" : "MedicationKnowledge.regulatory.substitution.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.regulatory.substitution.modifierExtension",
      "path" : "MedicationKnowledge.regulatory.substitution.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.regulatory.substitution.type",
      "path" : "MedicationKnowledge.regulatory.substitution.type",
      "short" : "Specifies the type of substitution allowed",
      "definition" : "Specifies the type of substitution allowed.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.regulatory.substitution.type",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.substitution.allowed",
      "path" : "MedicationKnowledge.regulatory.substitution.allowed",
      "short" : "Specifies if regulation allows for changes in the medication when dispensing",
      "definition" : "Specifies if regulation allows for changes in the medication when dispensing.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.regulatory.substitution.allowed",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "boolean"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.schedule",
      "path" : "MedicationKnowledge.regulatory.schedule",
      "short" : "Specifies the schedule of a medication in jurisdiction",
      "definition" : "Specifies the schedule of a medication in jurisdiction.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.regulatory.schedule",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.maxDispense",
      "path" : "MedicationKnowledge.regulatory.maxDispense",
      "short" : "The maximum number of units of the medication that can be dispensed in a period",
      "definition" : "The maximum number of units of the medication that can be dispensed in a period.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.regulatory.maxDispense",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.maxDispense.id",
      "path" : "MedicationKnowledge.regulatory.maxDispense.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.regulatory.maxDispense.extension",
      "path" : "MedicationKnowledge.regulatory.maxDispense.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.regulatory.maxDispense.modifierExtension",
      "path" : "MedicationKnowledge.regulatory.maxDispense.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.regulatory.maxDispense.quantity",
      "path" : "MedicationKnowledge.regulatory.maxDispense.quantity",
      "short" : "The maximum number of units of the medication that can be dispensed",
      "definition" : "The maximum number of units of the medication that can be dispensed.",
      "min" : 1,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.regulatory.maxDispense.quantity",
        "min" : 1,
        "max" : "1"
      },
      "type" : [{
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity"]
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.maxDispense.period",
      "path" : "MedicationKnowledge.regulatory.maxDispense.period",
      "short" : "The period that applies to the maximum number of units",
      "definition" : "The period that applies to the maximum number of units.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.regulatory.maxDispense.period",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Duration"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.kineticCharacteristic",
      "path" : "MedicationKnowledge.kineticCharacteristic",
      "short" : "The time course of drug absorption, distribution, metabolism and excretion of a medication from the body",
      "definition" : "The time course of drug absorption, distribution, metabolism and excretion of a medication from the body.",
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "MedicationKnowledge.kineticCharacteristic",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "BackboneElement"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.kineticCharacteristic.id",
      "path" : "MedicationKnowledge.kineticCharacteristic.id",
      "representation" : ["xmlAttr"],
      "short" : "Unique id for inter-element referencing",
      "definition" : "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "Element.id",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUri" : "id"
        }],
        "code" : "http://hl7.org/fhirpath/System.String"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.kineticCharacteristic.extension",
      "path" : "MedicationKnowledge.kineticCharacteristic.extension",
      "short" : "Additional content defined by implementations",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "alias" : ["extensions",
      "user content"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "Element.extension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "rim",
        "map" : "n/a"
      }]
    },
    {
      "id" : "MedicationKnowledge.kineticCharacteristic.modifierExtension",
      "path" : "MedicationKnowledge.kineticCharacteristic.modifierExtension",
      "short" : "Extensions that cannot be ignored even if unrecognized",
      "definition" : "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "comment" : "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "requirements" : "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
      "alias" : ["extensions",
      "user content",
      "modifiers"],
      "min" : 0,
      "max" : "*",
      "base" : {
        "path" : "BackboneElement.modifierExtension",
        "min" : 0,
        "max" : "*"
      },
      "type" : [{
        "code" : "Extension"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      },
      {
        "key" : "ext-1",
        "severity" : "error",
        "human" : "Must have either extensions or value[x], not both",
        "expression" : "extension.exists() != value.exists()",
        "xpath" : "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source" : "http://hl7.org/fhir/StructureDefinition/Extension"
      }],
      "isModifier" : true,
      "isModifierReason" : "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : "N/A"
      }]
    },
    {
      "id" : "MedicationKnowledge.kineticCharacteristic.type",
      "path" : "MedicationKnowledge.kineticCharacteristic.type",
      "short" : "Code specifying the type of kinetics",
      "definition" : "Code specifying the type of kinetics (e.g. area under the curve, half life period, lethal dose 50.).",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.kineticCharacteristic.type",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.kineticCharacteristic.value[x]",
      "path" : "MedicationKnowledge.kineticCharacteristic.value[x]",
      "short" : "Description of the characteristic",
      "definition" : "Description of the characteristic.",
      "min" : 0,
      "max" : "1",
      "base" : {
        "path" : "MedicationKnowledge.kineticCharacteristic.value[x]",
        "min" : 0,
        "max" : "1"
      },
      "type" : [{
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity"]
      },
      {
        "code" : "Duration"
      }],
      "constraint" : [{
        "key" : "ele-1",
        "severity" : "error",
        "human" : "All FHIR elements must have a @value or children",
        "expression" : "hasValue() or (children().count() > id.count())",
        "xpath" : "@value|f:*|h:div",
        "source" : "http://hl7.org/fhir/StructureDefinition/Element"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    }]
  },
  "differential" : {
    "element" : [{
      "id" : "MedicationKnowledge",
      "path" : "MedicationKnowledge",
      "short" : "Definition of Medication Knowledge",
      "definition" : "Information about a medication that is used to support knowledge.",
      "min" : 0,
      "max" : "*",
      "mustSupport" : false,
      "isModifier" : false,
      "mapping" : [{
        "identity" : "w5",
        "map" : "administrative.medication"
      }]
    },
    {
      "id" : "MedicationKnowledge.identifier",
      "path" : "MedicationKnowledge.identifier",
      "short" : "Business identifier for this medication",
      "definition" : "Business identifier for this medication.",
      "comment" : "This is a business identifier, not a resource identifier (see discussion).",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Identifier"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.code",
      "path" : "MedicationKnowledge.code",
      "short" : "Code that identifies this medication",
      "definition" : "A code that specifies this medication, or a textual description if no code is available. Usage note: This could be a standard medication code such as a code from RxNorm, SNOMED CT, IDMP etc. It could also be a national or local formulary code, optionally with translations to other code systems.",
      "comment" : "Depending on the context of use, the code that was actually selected by the user (prescriber, dispenser, etc.) will have the coding.userSelected set to true.  As described in the coding datatype: \"A coding may be marked as a \"userSelected\" if a user selected the particular coded value in a user interface (e.g. the user selects an item in a pick-list). If a user selected coding exists, it is the preferred choice for performing translations etc. Other codes can only be literal translations to alternative code systems, or codes at a lower level of granularity (e.g. a generic code for a vendor-specific primary one).",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationFormalRepresentation"
        }],
        "strength" : "example",
        "description" : "A coded concept that defines the type of a medication.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medication-codes"
      },
      "mapping" : [{
        "identity" : "script10.6",
        "map" : "coding.code = //element(*,MedicationType)/DrugCoded/ProductCode\r\rcoding.system = //element(*,MedicationType)/DrugCoded/ProductCodeQualifier\r\rcoding.display = //element(*,MedicationType)/DrugDescription"
      },
      {
        "identity" : "w5",
        "map" : "FiveWs.class"
      },
      {
        "identity" : "v2",
        "map" : "RXO-1.1-Requested Give Code.code / RXE-2.1-Give Code.code / RXD-2.1-Dispense/Give Code.code / RXG-4.1-Give Code.code /RXA-5.1-Administered Code.code / RXC-2.1 Component Code"
      },
      {
        "identity" : "rim",
        "map" : ".code"
      }]
    },
    {
      "id" : "MedicationKnowledge.status",
      "path" : "MedicationKnowledge.status",
      "short" : "active | inactive | entered-in-error",
      "definition" : "A code to indicate if the medication is in active use.  The status refers to the validity about the information of the medication and not to its medicinal properties.",
      "comment" : "This status is intended to identify if the medication in a local system is in active use within a drug database or inventory.  For example, a pharmacy system may create a new drug file record for a compounded product \"ABC Hospital Special Cream\" with an active status.  At some point in the future, it may be determined that the drug record was created with an error and the status is changed to \"entered in error\".   This status is not intended to specify if a medication is part of a particular formulary.  It is possible that the drug record may be referenced by multiple formularies or catalogues and each of those entries would have a separate status.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "code"
      }],
      "mustSupport" : false,
      "isModifier" : true,
      "isModifierReason" : "This element changes the interpretation of all descriptive attributes.",
      "isSummary" : true,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationKnowledgeStatus"
        }],
        "strength" : "required",
        "description" : "A coded concept defining if the medication is in active use.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medicationknowledge-status|4.6.0"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : ".statusCode"
      }]
    },
    {
      "id" : "MedicationKnowledge.author",
      "path" : "MedicationKnowledge.author",
      "short" : "Creator or owner of the knowledge or information about the medication",
      "definition" : "The creator or owner of the knowledge or information about the medication.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Organization"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "mapping" : [{
        "identity" : "w5",
        "map" : "FiveWs.actor"
      },
      {
        "identity" : "rim",
        "map" : "ManufacturedProduct.subjectOf.DocumentEvent.author"
      }]
    },
    {
      "id" : "MedicationKnowledge.sponsor",
      "path" : "MedicationKnowledge.sponsor",
      "short" : "Organization responsible for manufacturing of the item",
      "definition" : "Describes the details of the manufacturer of the medication product. This is not intended to represent the distributor of a medication product.  Describes the organization that is responsible for the manufacturing of the item and holds the registration to market the product in a jurisdiction. This might not be the company that physically manufactures the product.  May be known as Market Authorization Holder.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Organization"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.doseForm",
      "path" : "MedicationKnowledge.doseForm",
      "short" : "powder | tablets | capsule +",
      "definition" : "Describes the form of the item.  Powder; tablets; capsule.",
      "comment" : "When Medication is referenced from MedicationRequest, this is the ordered form.  When Medication is referenced within MedicationDispense, this is the dispensed form.  When Medication is referenced within MedicationAdministration, this is administered form.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationForm"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the form of a medication.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medication-form-codes"
      },
      "mapping" : [{
        "identity" : "script10.6",
        "map" : "coding.code =  //element(*,DrugCodedType)/FormCode\r\rcoding.system = //element(*,DrugCodedType)/FormSourceCode"
      },
      {
        "identity" : "v2",
        "map" : "RXO-5-Requested Dosage Form / RXE-6-Give Dosage Form / RXD-6-Actual Dosage Form / RXG-8-Give Dosage Form / RXA-8-Administered Dosage Form"
      },
      {
        "identity" : "rim",
        "map" : ".formCode"
      }]
    },
    {
      "id" : "MedicationKnowledge.amount",
      "path" : "MedicationKnowledge.amount",
      "short" : "Amount of drug in package",
      "definition" : "Specific amount of the drug in the packaged product.  For example, when specifying a product that has the same strength (For example, Insulin glargine 100 unit per mL solution for injection), this attribute provides additional clarification of the package amount (For example, 3 mL, 10mL, etc.).",
      "comment" : "This is the quantity of medication in a package.  To specify the strength of the medication, the Ingredient.strength attribute is used.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "rim",
        "map" : ".quantity"
      }]
    },
    {
      "id" : "MedicationKnowledge.synonym",
      "path" : "MedicationKnowledge.synonym",
      "short" : "Additional names for a medication",
      "definition" : "Additional names for a medication, for example, the name(s) given to a medication in different countries.  For example, acetaminophen and paracetamol or salbutamol and albuterol.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "string"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.relatedMedicationKnowledge",
      "path" : "MedicationKnowledge.relatedMedicationKnowledge",
      "short" : "Associated or related medication information",
      "definition" : "Associated or related medications. For example, if the medication is a branded product (e.g. Crestor), this is the Therapeutic Moeity (e.g. Rosuvastatin) or if this is a generic medication (e.g. Rosuvastatin), this would link to a branded product (e.g. Crestor.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.relatedMedicationKnowledge.type",
      "path" : "MedicationKnowledge.relatedMedicationKnowledge.type",
      "short" : "Category of medicationKnowledge",
      "definition" : "The category of the associated medication knowledge reference.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.relatedMedicationKnowledge.reference",
      "path" : "MedicationKnowledge.relatedMedicationKnowledge.reference",
      "short" : "Associated documentation about the associated medication knowledge",
      "definition" : "Associated documentation about the associated medication knowledge.",
      "min" : 1,
      "max" : "*",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/MedicationKnowledge"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.associatedMedication",
      "path" : "MedicationKnowledge.associatedMedication",
      "short" : "A medication resource that is associated with this medication",
      "definition" : "Links to associated medications that could be prescribed, dispensed or administered.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Medication"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.associatedDefinition",
      "path" : "MedicationKnowledge.associatedDefinition",
      "short" : "A definition resource that is associated with this medication",
      "definition" : "Associated definitions for this medication.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/MedicinalProductDefinition"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.productType",
      "path" : "MedicationKnowledge.productType",
      "short" : "Category of the medication or product",
      "definition" : "Category of the medication or product (e.g. branded product, therapeutic moeity, generic product, innovator product, etc.).",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.monograph",
      "path" : "MedicationKnowledge.monograph",
      "short" : "Associated documentation about the medication",
      "definition" : "Associated documentation about the medication.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.monograph.type",
      "path" : "MedicationKnowledge.monograph.type",
      "short" : "The category of medication document",
      "definition" : "The category of documentation about the medication. (e.g. professional monograph, patient education monograph).",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.monograph.source",
      "path" : "MedicationKnowledge.monograph.source",
      "short" : "Associated documentation about the medication",
      "definition" : "Associated documentation about the medication.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/DocumentReference"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.ingredient",
      "path" : "MedicationKnowledge.ingredient",
      "short" : "Active or inactive ingredient",
      "definition" : "Identifies a particular constituent of interest in the product.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.ingredient.item",
      "path" : "MedicationKnowledge.ingredient.item",
      "short" : "Medication(s) or MedicinalProductIngredient(s) contained in the medication",
      "definition" : "The actual ingredient - either a substance (simple ingredient) or another medication.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "CodeableReference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Ingredient"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true,
      "mapping" : [{
        "identity" : "script10.6",
        "map" : "coding.code = //element(*,MedicationType)/DrugCoded/ProductCode\r\rcoding.system = //element(*,MedicationType)/DrugCoded/ProductCodeQualifier\r\rcoding.display = //element(*,MedicationType)/DrugDescription"
      },
      {
        "identity" : "v2",
        "map" : "RXC-2-Component Code  if medication: RXO-1-Requested Give Code / RXE-2-Give Code / RXD-2-Dispense/Give Code / RXG-4-Give Code / RXA-5-Administered Code"
      },
      {
        "identity" : "rim",
        "map" : ".player"
      }]
    },
    {
      "id" : "MedicationKnowledge.ingredient.isActive",
      "path" : "MedicationKnowledge.ingredient.isActive",
      "short" : "Active ingredient indicator",
      "definition" : "Indication of whether this ingredient affects the therapeutic action of the drug.",
      "requirements" : "True indicates that the ingredient affects the therapeutic action of the drug (i.e. active). \rFalse indicates that the ingredient does not affect the therapeutic action of the drug (i.e. inactive).",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationIngredientIsActive"
        }],
        "strength" : "example",
        "valueSet" : "http://terminology.hl7.org/ValueSet/v3-RoleClassIngredientEntity"
      },
      "mapping" : [{
        "identity" : "rim",
        "map" : "NA"
      }]
    },
    {
      "id" : "MedicationKnowledge.ingredient.strength[x]",
      "path" : "MedicationKnowledge.ingredient.strength[x]",
      "short" : "Quantity of ingredient present",
      "definition" : "Specifies how many (or how much) of the items there are in this Medication.  For example, 250 mg per tablet.  This is expressed as a ratio where the numerator is 250mg and the denominator is 1 tablet but can also be expressed a quantity when the denominator is assumed to be 1 tablet.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Ratio"
      },
      {
        "code" : "CodeableConcept"
      },
      {
        "code" : "Quantity"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationIngredientStrength"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the strength of an ingredient.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medication-ingredientstrength"
      },
      "mapping" : [{
        "identity" : "script10.6",
        "map" : "//element(*,DrugCodedType)/Strength"
      },
      {
        "identity" : "v2",
        "map" : "RXC-3-Component Amount & RXC-4-Component Units  if medication: RXO-2-Requested Give Amount - Minimum & RXO-4-Requested Give Units / RXO-3-Requested Give Amount - Maximum & RXO-4-Requested Give Units / RXO-11-Requested Dispense Amount & RXO-12-Requested Dispense Units / RXE-3-Give Amount - Minimum & RXE-5-Give Units / RXE-4-Give Amount - Maximum & RXE-5-Give Units / RXE-10-Dispense Amount & RXE-10-Dispense Units"
      },
      {
        "identity" : "rim",
        "map" : ".quantity"
      }]
    },
    {
      "id" : "MedicationKnowledge.device",
      "path" : "MedicationKnowledge.device",
      "short" : "A device associated with the medication (for example, a drug coated catheter or a drug impregnated dressing)",
      "definition" : "A device associated with the medication (for example, a drug coated catheter or a drug impregnated dressing).",
      "requirements" : "This attribute should only be populated for those devices that have the drug incorporated in them.  If a device used to administer a medication, for example an applicator or a syringe, needs to be specified, use MedicationKnowledge.packaging.device.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Device"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.preparationInstruction",
      "path" : "MedicationKnowledge.preparationInstruction",
      "short" : "The instructions for preparing the medication",
      "definition" : "The instructions for preparing the medication.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "markdown"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.intendedRoute",
      "path" : "MedicationKnowledge.intendedRoute",
      "short" : "The intended or approved route of administration",
      "definition" : "The intended or approved route of administration.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationRoute"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the intended route of administration.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/route-codes"
      }
    },
    {
      "id" : "MedicationKnowledge.cost",
      "path" : "MedicationKnowledge.cost",
      "short" : "The pricing of the medication",
      "definition" : "The price of the medication.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.cost.effectiveDate",
      "path" : "MedicationKnowledge.cost.effectiveDate",
      "short" : "The date range for which the cost is effective",
      "definition" : "The date range for which the cost information of the medication is effective.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Period"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.cost.type",
      "path" : "MedicationKnowledge.cost.type",
      "short" : "The category of the cost information",
      "definition" : "The category of the cost information.  For example, manufacturers' cost, patient cost, claim reimbursement cost, actual acquisition cost.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.cost.source",
      "path" : "MedicationKnowledge.cost.source",
      "short" : "The source or owner for the price information",
      "definition" : "The source or owner that assigns the price to the medication.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "string"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.cost.cost[x]",
      "path" : "MedicationKnowledge.cost.cost[x]",
      "short" : "The price or category of the cost of the medication",
      "definition" : "The price or representation of the cost (for example, Band A, Band B or $, $$) of the medication.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "Money"
      },
      {
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationCostCategory"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the category of a medication.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medication-cost-category"
      }
    },
    {
      "id" : "MedicationKnowledge.monitoringProgram",
      "path" : "MedicationKnowledge.monitoringProgram",
      "short" : "Program under which a medication is reviewed",
      "definition" : "The program under which the medication is reviewed.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : true
    },
    {
      "id" : "MedicationKnowledge.monitoringProgram.type",
      "path" : "MedicationKnowledge.monitoringProgram.type",
      "short" : "Type of program under which the medication is monitored",
      "definition" : "Type of program under which the medication is monitored.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.monitoringProgram.name",
      "path" : "MedicationKnowledge.monitoringProgram.name",
      "short" : "Name of the reviewing program",
      "definition" : "Name of the reviewing program.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "string"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline",
      "path" : "MedicationKnowledge.indicationGuideline",
      "short" : "Guidelines or protocols for administration of the medication for an indication",
      "definition" : "Guidelines or protocols that are applicable for the administration of the medication based on indication.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.indication",
      "path" : "MedicationKnowledge.indicationGuideline.indication",
      "short" : "Indication for use that applies to the specific administration guideline",
      "definition" : "Indication or reason for use of the medication that applies to the specific administration guideline.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "CodeableReference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/ClinicalUseIssue"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline",
      "short" : "Guidelines for dosage of the medication",
      "definition" : "The guidelines for the dosage of the medication for the indication.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.treatmentIntent",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.treatmentIntent",
      "short" : "Intention of the treatment",
      "definition" : "The overall intention of the treatment, for example, prophylactic, supporative, curative, etc.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.dosage",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.dosage",
      "short" : "Dosage for the medication for the specific guidelines",
      "definition" : "Dosage for the medication for the specific guidelines.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.dosage.type",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.dosage.type",
      "short" : "Category of dosage for a medication",
      "definition" : "The type or category of dosage for a given medication (for example, prophylaxis, maintenance, therapeutic, etc.).",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.dosage.dosage",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.dosage.dosage",
      "short" : "Dosage for the medication for the specific guidelines",
      "definition" : "Dosage for the medication for the specific guidelines.",
      "min" : 1,
      "max" : "*",
      "type" : [{
        "code" : "Dosage"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.administrationTreatment",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.administrationTreatment",
      "short" : "Type of treatment the guideline applies to",
      "definition" : "The type of the treatment that the guideline applies to, for example, long term therapy, first line treatment, etc.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic",
      "short" : "Characteristics of the patient that are relevant to the administration guidelines",
      "definition" : "Characteristics of the patient that are relevant to the administration guidelines (for example, height, weight, gender, etc.).",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.type",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.type",
      "short" : "Categorization of specific characteristic that is relevant to the administration guideline",
      "definition" : "The categorization of the specific characteristic that is relevant to the administration guideline (e.g. height, weight, gender).",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.value[x]",
      "path" : "MedicationKnowledge.indicationGuideline.dosingGuideline.patientCharacteristic.value[x]",
      "short" : "The specific characteristic",
      "definition" : "The specific characteristic (e.g. height, weight, gender, etc.).",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      },
      {
        "code" : "Quantity"
      },
      {
        "code" : "Range"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.medicineClassification",
      "path" : "MedicationKnowledge.medicineClassification",
      "short" : "Categorization of the medication within a formulary or classification system",
      "definition" : "Categorization of the medication within a formulary or classification system.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.medicineClassification.type",
      "path" : "MedicationKnowledge.medicineClassification.type",
      "short" : "The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification)",
      "definition" : "The type of category for the medication (for example, therapeutic classification, therapeutic sub-classification).",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.medicineClassification.classification",
      "path" : "MedicationKnowledge.medicineClassification.classification",
      "short" : "Specific category assigned to the medication",
      "definition" : "Specific category assigned to the medication (e.g. anti-infective, anti-hypertensive, antibiotic, etc.).",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging",
      "path" : "MedicationKnowledge.packaging",
      "short" : "Details about packaged medications",
      "definition" : "Information that only applies to packages (not products).",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.identifier",
      "path" : "MedicationKnowledge.packaging.identifier",
      "short" : "Business identifier of the packaged medication",
      "definition" : "The business identifier of the packaged medication.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Identifier"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.cost",
      "path" : "MedicationKnowledge.packaging.cost",
      "short" : "Cost of the packaged medication",
      "definition" : "The cost of the packaged medication.",
      "min" : 0,
      "max" : "1",
      "contentReference" : "#MedicationKnowledge.cost",
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.type",
      "path" : "MedicationKnowledge.packaging.type",
      "short" : "A code that defines the specific type of packaging that the medication can be found in",
      "definition" : "A code that defines the specific type of packaging that the medication can be found in (e.g. blister sleeve, tube, bottle).",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationPackageType"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the type of packaging of a medication.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medicationknowledge-package-type"
      }
    },
    {
      "id" : "MedicationKnowledge.packaging.quantity",
      "path" : "MedicationKnowledge.packaging.quantity",
      "short" : "The number of product units the package would contain if fully loaded",
      "definition" : "The number of product units the package would contain if fully loaded.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.device",
      "path" : "MedicationKnowledge.packaging.device",
      "short" : "The device used to administer the medication (e.g. scoop, applicator, syringe)",
      "definition" : "The device used to administer the medication (e.g. scoop, applicator, syringe).",
      "requirements" : "If specifying devices impregnated with medication, use MedicationKnowledge.device.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Device"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.material",
      "path" : "MedicationKnowledge.packaging.material",
      "short" : "Material type of the package item",
      "definition" : "Material type of the package item.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.packaging.packaging",
      "path" : "MedicationKnowledge.packaging.packaging",
      "short" : "Allows packages within packages",
      "definition" : "Allows packages within packages (e.g. blister packages within a box or vials of medications within a box).",
      "min" : 0,
      "max" : "*",
      "contentReference" : "#MedicationKnowledge.packaging",
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.drugCharacteristic",
      "path" : "MedicationKnowledge.drugCharacteristic",
      "short" : "Specifies descriptive properties of the medicine",
      "definition" : "Specifies descriptive properties of the medicine, such as color, shape, imprints, etc.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.drugCharacteristic.type",
      "path" : "MedicationKnowledge.drugCharacteristic.type",
      "short" : "Code specifying the type of characteristic of medication",
      "definition" : "A code specifying which characteristic of the medicine is being described (for example, colour, shape, imprint).",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false,
      "binding" : {
        "extension" : [{
          "url" : "http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName",
          "valueString" : "MedicationCharacteristic"
        }],
        "strength" : "example",
        "description" : "A coded concept defining the characteristic types of a medication.",
        "valueSet" : "http://hl7.org/fhir/ValueSet/medicationknowledge-characteristic"
      }
    },
    {
      "id" : "MedicationKnowledge.drugCharacteristic.value[x]",
      "path" : "MedicationKnowledge.drugCharacteristic.value[x]",
      "short" : "Description of the characteristic",
      "definition" : "Description of the characteristic.",
      "comment" : "The description should be provided as a CodeableConcept, SimpleQuantity or an image.  The description can be a string only when these others are not available.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      },
      {
        "code" : "string"
      },
      {
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity"]
      },
      {
        "code" : "base64Binary"
      },
      {
        "code" : "Attachment"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.clinicalUseIssue",
      "path" : "MedicationKnowledge.clinicalUseIssue",
      "short" : "Potential clinical issue with or between medication(s)",
      "definition" : "Potential clinical issue with or between medication(s) (for example, drug-drug interaction, drug-disease contraindication, drug-allergy interaction, etc.).",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/ClinicalUseIssue"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory",
      "path" : "MedicationKnowledge.regulatory",
      "short" : "Regulatory information about a medication",
      "definition" : "Regulatory information about a medication.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.regulatoryAuthority",
      "path" : "MedicationKnowledge.regulatory.regulatoryAuthority",
      "short" : "Specifies the authority of the regulation",
      "definition" : "The authority that is specifying the regulations.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "Reference",
        "targetProfile" : ["http://hl7.org/fhir/StructureDefinition/Organization"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.substitution",
      "path" : "MedicationKnowledge.regulatory.substitution",
      "short" : "Specifies if changes are allowed when dispensing a medication from a regulatory perspective",
      "definition" : "Specifies if changes are allowed when dispensing a medication from a regulatory perspective.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.substitution.type",
      "path" : "MedicationKnowledge.regulatory.substitution.type",
      "short" : "Specifies the type of substitution allowed",
      "definition" : "Specifies the type of substitution allowed.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.substitution.allowed",
      "path" : "MedicationKnowledge.regulatory.substitution.allowed",
      "short" : "Specifies if regulation allows for changes in the medication when dispensing",
      "definition" : "Specifies if regulation allows for changes in the medication when dispensing.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "boolean"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.schedule",
      "path" : "MedicationKnowledge.regulatory.schedule",
      "short" : "Specifies the schedule of a medication in jurisdiction",
      "definition" : "Specifies the schedule of a medication in jurisdiction.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.maxDispense",
      "path" : "MedicationKnowledge.regulatory.maxDispense",
      "short" : "The maximum number of units of the medication that can be dispensed in a period",
      "definition" : "The maximum number of units of the medication that can be dispensed in a period.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.maxDispense.quantity",
      "path" : "MedicationKnowledge.regulatory.maxDispense.quantity",
      "short" : "The maximum number of units of the medication that can be dispensed",
      "definition" : "The maximum number of units of the medication that can be dispensed.",
      "min" : 1,
      "max" : "1",
      "type" : [{
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity"]
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.regulatory.maxDispense.period",
      "path" : "MedicationKnowledge.regulatory.maxDispense.period",
      "short" : "The period that applies to the maximum number of units",
      "definition" : "The period that applies to the maximum number of units.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Duration"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.kineticCharacteristic",
      "path" : "MedicationKnowledge.kineticCharacteristic",
      "short" : "The time course of drug absorption, distribution, metabolism and excretion of a medication from the body",
      "definition" : "The time course of drug absorption, distribution, metabolism and excretion of a medication from the body.",
      "min" : 0,
      "max" : "*",
      "type" : [{
        "code" : "BackboneElement"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.kineticCharacteristic.type",
      "path" : "MedicationKnowledge.kineticCharacteristic.type",
      "short" : "Code specifying the type of kinetics",
      "definition" : "Code specifying the type of kinetics (e.g. area under the curve, half life period, lethal dose 50.).",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "CodeableConcept"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    },
    {
      "id" : "MedicationKnowledge.kineticCharacteristic.value[x]",
      "path" : "MedicationKnowledge.kineticCharacteristic.value[x]",
      "short" : "Description of the characteristic",
      "definition" : "Description of the characteristic.",
      "min" : 0,
      "max" : "1",
      "type" : [{
        "code" : "Quantity",
        "profile" : ["http://hl7.org/fhir/StructureDefinition/SimpleQuantity"]
      },
      {
        "code" : "Duration"
      }],
      "mustSupport" : false,
      "isModifier" : false,
      "isSummary" : false
    }]
  }
}

Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.