Release 5 Preview #1

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Evidence-example

Clinical Decision Support Work GroupMaturity Level: N/AStandards Status: InformativeCompartments: Not linked to any defined compartments

This is the narrative for the resource. See also the XML, JSON or Turtle format. This example conforms to the profile Evidence.


Generated Narrative with Details

id: example

title: Corticosteroids vs No corticosteroids for Patients with Sepsis with Mortality (60 days to 1 year)

status: draft

relatedArtifact:

description: Mortality reduced with RR 0.94 with Corticosteroids vs no corticosteroids for patients with sepsis

ReferentGroups

-DescriptionEvidenceSourceIntendedGroupDirectnessMatch
*Patients with sepsis???Patients with sepsis??? (Details : {http://terminology.hl7.org/CodeSystem/directness code 'null' = 'null', given as '???'})

variableDefinition

description: Mortality Longer term (60 days to 1 year)

variableRole: measured variable (Details : {http://terminology.hl7.org/CodeSystem/variable-role code 'measuredVariable' = 'measured variable', given as 'measured variable'})

actualDefinition: many studies had shorter term outcomes

intendedDefinition: Mortality Longer term (Follow up: 60 days to 1 year)

directnessMatch: moderate (Details : {http://terminology.hl7.org/CodeSystem/directness code 'moderate' = 'Moderate quality match', given as 'moderate'})

variableDefinition

description: Corticosteroids

variableRole: exposure (Details : {http://terminology.hl7.org/CodeSystem/variable-role code 'exposure' = 'exposure', given as 'exposure'})

actualDefinition: ???

intendedDefinition: Corticosteroids

directnessMatch: ??? (Details : {http://terminology.hl7.org/CodeSystem/directness code 'null' = 'null', given as '???'})

variableDefinition

description: No corticosteroids

variableRole: referenceExposure (Details : {http://terminology.hl7.org/CodeSystem/variable-role code 'referenceExposure' = 'reference exposure', given as 'referenceExposure'})

actualDefinition: ???

intendedDefinition: No corticosteroids

directnessMatch: ??? (Details : {http://terminology.hl7.org/CodeSystem/directness code 'null' = 'null', given as '???'})

synthesisType: summary data meta-analysis (Details : {http://terminology.hl7.org/CodeSystem/synthesis-type code 'std-MA' = 'summary data meta-analysis', given as 'summary data meta-analysis'})

studyType: randomized trial (Details : {http://terminology.hl7.org/CodeSystem/study-type code 'RCT' = 'randomized trial', given as 'randomized trial'})

statistic: ,

certainty

description: Low, due to serious imprecision and indirectness.

rating: Low quality (Details : {http://terminology.hl7.org/CodeSystem/certainty-rating code 'low' = 'Low quality', given as 'Low quality'})

certaintySubcomponent

note: Note that all studies that reported 90 day to 1 year mortality also reported 28-30 day mortality: the CI 95% around the pooled effect for short term mortality also excludes no effect: RR 0.91 (CI 95% 0.84 - 0.98).

type: Risk of bias (Details : {http://terminology.hl7.org/CodeSystem/certainty-subcomponent-type code 'RiskOfBias' = 'Risk of bias', given as 'Risk of bias'})

rating: no serious concern (Details : {http://terminology.hl7.org/CodeSystem/certainty-subcomponent-rating code 'no-concern' = 'no serious concern', given as 'no serious concern'})

certaintySubcomponent

type: Inconsistency (Details : {http://terminology.hl7.org/CodeSystem/certainty-subcomponent-type code 'Inconsistency' = 'Inconsistency', given as 'Inconsistency'})

rating: no serious concern (Details : {http://terminology.hl7.org/CodeSystem/certainty-subcomponent-rating code 'no-concern' = 'no serious concern', given as 'no serious concern'})

certaintySubcomponent

note: Only a small proportion of studies reported longer-term mortality.

type: Indirectness (Details : {http://terminology.hl7.org/CodeSystem/certainty-subcomponent-type code 'Indirectness' = 'Indirectness', given as 'Indirectness'})

rating: serious concern (Details : {http://terminology.hl7.org/CodeSystem/certainty-subcomponent-rating code 'serious-concern' = 'serious concern', given as 'serious concern'})

certaintySubcomponent

note: Confidence interval includes no effect.

type: Imprecision (Details : {http://terminology.hl7.org/CodeSystem/certainty-subcomponent-type code 'Imprecision' = 'Imprecision', given as 'Imprecision'})

rating: serious concern (Details : {http://terminology.hl7.org/CodeSystem/certainty-subcomponent-rating code 'serious-concern' = 'serious concern', given as 'serious concern'})

certaintySubcomponent

type: Publication bias (Details : {http://terminology.hl7.org/CodeSystem/certainty-subcomponent-type code 'PublicationBias' = 'Publication bias', given as 'Publication bias'})

rating: no serious concern (Details : {http://terminology.hl7.org/CodeSystem/certainty-subcomponent-rating code 'no-concern' = 'no serious concern', given as 'no serious concern'})


 

 

Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.