Medicationdispense0306.xml

Dispense for Intravenous Chemotherapy (inpatient order) - Alemtuzumab (RxNorm Code) - completed with multiple dosageInstruction lines (id = "meddisp0306")

<MedicationDispense xmlns="http://hl7.org/fhir">
    <id value="meddisp0306"/>
    <text><status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: meddisp0306</p><p><b>contained</b>: </p><p><b>status</b>: in-progress</p><p><b>medication</b>: Alemtuzumab 10mg/ml (Lemtrada). Generated Summary: id: med0303; Alemtuzumab 10mg/ml
         (Lemtrada) <span>(Details : {RxNorm code '1594660' = '1594660', given as 'Alemtuzumab 10mg/ml (Lemtrada)'})</span></p><p><b>patient</b>: <a>Donald Duck</a></p><p><b>dispenser</b>: <a>Rob van den Berk</a></p><p><b>authorizingPrescription</b>: <a>MedicationRequest/medrx0317</a></p><p><b>type</b>: Daily Fill <span>(Details : {http://hl7.org/fhir/ValueSet/v3-ActPharmacySupplyType code 'DF' = 'DF', given
           as 'Daily Fill'})</span></p><p><b>quantity</b>: 5 415818006<span> (Details: SNOMED CT code 415818006 = 'Vial - unit of product usage (qualifier value)')</span></p><p><b>daysSupply</b>: 7 Day<span> (Details: UCUM code d = 'd')</span></p><p><b>whenPrepared</b>: 15/01/2015 9:20:00 PM</p><p><b>dosageInstruction</b>: , , </p></div></text><contained>
        <Medication>
            <id value="med0303"/>
            <code>
                <coding>
                    <system value="http://www.nlm.nih.gov/research/umls/rxnorm"/>
                    <code value="1594660"/>
                    <display value="Alemtuzumab 10mg/ml (Lemtrada)"/>
                </coding>
            </code>
        </Medication>
    </contained>
    <status value="in-progress"/>
    <medicationReference>
        <!--    Linked to a RESOURCE Medication    -->
        <reference value="#med0303"/>
        <display value="Alemtuzumab 10mg/ml (Lemtrada)"/>
    </medicationReference>
    <patient>
        <reference value="Patient/pat1"/>
        <display value="Donald Duck"/>
    </patient>
    <dispenser>
        <reference value="Practitioner/f006"/>
        <display value="Rob van den Berk"/>
    </dispenser>
    <authorizingPrescription>
        <reference value="MedicationRequest/medrx0317"/>
    </authorizingPrescription>
    <type>
        <coding>
            <system value="http://hl7.org/fhir/ValueSet/v3-ActPharmacySupplyType"/>
            <code value="DF"/>
            <display value="Daily Fill"/>
        </coding>
    </type>
    <quantity>
        <value value="5"/>
        <system value="http://snomed.info/sct"/>
        <code value="415818006"/>
    </quantity>
    <daysSupply>
        <value value="7"/>
        <unit value="Day"/>
        <system value="http://unitsofmeasure.org"/>
        <code value="d"/>
    </daysSupply>
    <whenPrepared value="2015-01-15T10:20:00Z"/>
    <dosageInstruction>
        <sequence value="1"/>
        <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended
     maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to
     12 wk"/>
        <additionalInstructions>
            <text value="Rapidly increase dose until tolerated"/>
        </additionalInstructions>
        <additionalInstructions>
            <text value="Administer on alternate days"/>
        </additionalInstructions>
        <timing>
            <repeat>
                <duration value="12"/>
                <durationUnit value="wk"/>
                <frequency value="3"/>
                <period value="1"/>
                <periodUnit value="wk"/>
            </repeat>
        </timing>
        <route>
            <coding>
                <system value="http://snomed.info/sct"/>
                <code value="47625008"/>
                <display value="Intravenous route (qualifier value)"/>
            </coding>
        </route>
        <method>
            <coding>
                <system value="http://snomed.info/sct"/>
                <code value="422145002"/>
                <display value="Inject - dosing instruction imperative (qualifier value)"/>
            </coding>
        </method>
        <doseQuantity>
            <value value="3"/>
            <unit value="mg"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="mg"/>
        </doseQuantity>
    </dosageInstruction>
    <dosageInstruction>
        <sequence value="2"/>
        <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended
     maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to
     12 wk"/>
        <additionalInstructions>
            <text value="Rapidly increase dose until tolerated"/>
        </additionalInstructions>
        <additionalInstructions>
            <text value="Administer on alternate days"/>
        </additionalInstructions>
        <timing>
            <repeat>
                <duration value="12"/>
                <durationUnit value="wk"/>
                <frequency value="3"/>
                <period value="1"/>
                <periodUnit value="wk"/>
            </repeat>
        </timing>
        <route>
            <coding>
                <system value="http://snomed.info/sct"/>
                <code value="47625008"/>
                <display value="Intravenous route (qualifier value)"/>
            </coding>
        </route>
        <method>
            <coding>
                <system value="http://snomed.info/sct"/>
                <code value="422145002"/>
                <display value="Inject - dosing instruction imperative (qualifier value)"/>
            </coding>
        </method>
        <doseQuantity>
            <value value="10"/>
            <unit value="mg"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="mg"/>
        </doseQuantity>
    </dosageInstruction>  
    <dosageInstruction>
        <sequence value="3"/>
        <text value="Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended
     maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to
     12 wk"/>
        <additionalInstructions>
            <text value="Rapidly increase dose until tolerated"/>
        </additionalInstructions>
        <additionalInstructions>
            <text value="Administer on alternate days"/>
        </additionalInstructions>
        <timing>
            <repeat>
                <duration value="12"/>
                <durationUnit value="wk"/>
                <frequency value="3"/>
                <period value="1"/>
                <periodUnit value="wk"/>
            </repeat>
        </timing>
        <route>
            <coding>
                <system value="http://snomed.info/sct"/>
                <code value="47625008"/>
                <display value="Intravenous route (qualifier value)"/>
            </coding>
        </route>
        <method>
            <coding>
                <system value="http://snomed.info/sct"/>
                <code value="422145002"/>
                <display value="Inject - dosing instruction imperative (qualifier value)"/>
            </coding>
        </method>
        <doseQuantity>
            <value value="30"/>
            <unit value="mg"/>
            <system value="http://unitsofmeasure.org"/>
            <code value="mg"/>
        </doseQuantity>
    </dosageInstruction>
</MedicationDispense>