This page is part of the FHIR Specification (v1.6.0: STU 3 Ballot 4). The current version which supercedes this version is 5.0.0. For a full list of available versions, see the Directory of published versions . Page versions: R5 R4B R4 R3
Medicationdispense0306.ttl

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Dispense for Intravenous Chemotherapy (inpatient order) - Alemtuzumab (RxNorm Code) - completed with multiple dosageInstruction lines
@prefix fhir: <http://hl7.org/fhir/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://hl7.org/fhir/MedicationDispense/meddisp0306> a fhir:MedicationDispense;
  fhir:nodeRole fhir:treeRoot;
  fhir:Resource.id [ fhir:value "meddisp0306"];
  fhir:DomainResource.text [
     fhir:Narrative.status [ fhir:value "generated" ];
     fhir:Narrative.div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p><b>Generated Narrative with Details</b></p><p><b>id</b>: meddisp0306</p><p><b>contained</b>: </p><p><b>status</b>: in-progress</p><p><b>medication</b>: Alemtuzumab 10mg/ml (Lemtrada). Generated Summary: id: med0303; Alemtuzumab 10mg/ml (Lemtrada) <span>(Details : {RxNorm code '1594660' = '??', given as 'Alemtuzumab 10mg/ml (Lemtrada)'})</span></p><p><b>patient</b>: <a>Donald Duck</a></p><p><b>dispenser</b>: <a>Rob van den Berk</a></p><p><b>authorizingPrescription</b>: <a>MedicationOrder/medrx0317</a></p><p><b>type</b>: Daily Fill <span>(Details : {http://hl7.org/fhir/ValueSet/v3-ActPharmacySupplyType code 'DF' = '??', given as 'Daily Fill'})</span></p><p><b>quantity</b>: 5 415818006<span> (Details: SNOMED CT code 415818006 = 'Vial - unit of product usage (qualifier value)')</span></p><p><b>daysSupply</b>: 7 Day<span> (Details: http://unitsofmeasure.org code d = 'd')</span></p><p><b>whenPrepared</b>: 15/01/2015 9:20:00 PM</p><blockquote><p><b>dosageInstruction</b></p><p><b>text</b>: Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk</p><p><b>additionalInstructions</b>: Rapidly increase dose until tolerated <span>(Details )</span>, Administer on alternate days <span>(Details )</span></p><p><b>timing</b>: Duration 12weeks, Do 3 per 1 weeks</p><p><b>route</b>: Intravenous route (qualifier value) <span>(Details : {SNOMED CT code '47625008' = 'Intravenous route (qualifier value)', given as 'Intravenous route (qualifier value)'})</span></p><p><b>method</b>: Inject - dosing instruction imperative (qualifier value) <span>(Details : {SNOMED CT code '422145002' = 'Inject - dosing instruction imperative (qualifier value)', given as 'Inject - dosing instruction imperative (qualifier value)'})</span></p><p><b>dose</b>: 3 mg<span> (Details: http://unitsofmeasure.org code mg = 'mg')</span></p></blockquote><blockquote><p><b>dosageInstruction</b></p><p><b>text</b>: Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk</p><p><b>additionalInstructions</b>: Rapidly increase dose until tolerated <span>(Details )</span>, Administer on alternate days <span>(Details )</span></p><p><b>timing</b>: Duration 12weeks, Do 3 per 1 weeks</p><p><b>route</b>: Intravenous route (qualifier value) <span>(Details : {SNOMED CT code '47625008' = 'Intravenous route (qualifier value)', given as 'Intravenous route (qualifier value)'})</span></p><p><b>method</b>: Inject - dosing instruction imperative (qualifier value) <span>(Details : {SNOMED CT code '422145002' = 'Inject - dosing instruction imperative (qualifier value)', given as 'Inject - dosing instruction imperative (qualifier value)'})</span></p><p><b>dose</b>: 10 mg<span> (Details: http://unitsofmeasure.org code mg = 'mg')</span></p></blockquote><blockquote><p><b>dosageInstruction</b></p><p><b>text</b>: Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk</p><p><b>additionalInstructions</b>: Rapidly increase dose until tolerated <span>(Details )</span>, Administer on alternate days <span>(Details )</span></p><p><b>timing</b>: Duration 12weeks, Do 3 per 1 weeks</p><p><b>route</b>: Intravenous route (qualifier value) <span>(Details : {SNOMED CT code '47625008' = 'Intravenous route (qualifier value)', given as 'Intravenous route (qualifier value)'})</span></p><p><b>method</b>: Inject - dosing instruction imperative (qualifier value) <span>(Details : {SNOMED CT code '422145002' = 'Inject - dosing instruction imperative (qualifier value)', given as 'Inject - dosing instruction imperative (qualifier value)'})</span></p><p><b>dose</b>: 30 mg<span> (Details: http://unitsofmeasure.org code mg = 'mg')</span></p></blockquote></div>"
  ];
  fhir:DomainResource.contained [
     a fhir:Medication;
     fhir:index 0;
     fhir:Resource.id [ fhir:value "med0303" ];
     fhir:Medication.code [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:Coding.system [ fhir:value "http://www.nlm.nih.gov/research/umls/rxnorm" ];
         fhir:Coding.code [ fhir:value "1594660" ];
         fhir:Coding.display [ fhir:value "Alemtuzumab 10mg/ml (Lemtrada)" ]
       ]
     ]
  ];
  fhir:MedicationDispense.status [ fhir:value "in-progress"];
  fhir:MedicationDispense.medicationReference [
     fhir:Reference.reference [ fhir:value "#med0303" ];
     fhir:Reference.display [ fhir:value "Alemtuzumab 10mg/ml (Lemtrada)" ]
  ];
  fhir:MedicationDispense.patient [
     fhir:link <http://hl7.org/fhir/Patient/pat1>;
     fhir:Reference.reference [ fhir:value "Patient/pat1" ];
     fhir:Reference.display [ fhir:value "Donald Duck" ]
  ];
  fhir:MedicationDispense.dispenser [
     fhir:link <http://hl7.org/fhir/Practitioner/f006>;
     fhir:Reference.reference [ fhir:value "Practitioner/f006" ];
     fhir:Reference.display [ fhir:value "Rob van den Berk" ]
  ];
  fhir:MedicationDispense.authorizingPrescription [
     fhir:index 0;
     fhir:link <http://hl7.org/fhir/MedicationOrder/medrx0317>;
     fhir:Reference.reference [ fhir:value "MedicationOrder/medrx0317" ]
  ];
  fhir:MedicationDispense.type [
     fhir:CodeableConcept.coding [
       fhir:index 0;
       fhir:Coding.system [ fhir:value "http://hl7.org/fhir/ValueSet/v3-ActPharmacySupplyType" ];
       fhir:Coding.code [ fhir:value "DF" ];
       fhir:Coding.display [ fhir:value "Daily Fill" ]
     ]
  ];
  fhir:MedicationDispense.quantity [
     fhir:Quantity.value [ fhir:value "5"^^xsd:decimal ];
     fhir:Quantity.system [ fhir:value "http://snomed.info/sct" ];
     fhir:Quantity.code [ fhir:value "415818006" ]
  ];
  fhir:MedicationDispense.daysSupply [
     fhir:Quantity.value [ fhir:value "7"^^xsd:decimal ];
     fhir:Quantity.unit [ fhir:value "Day" ];
     fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
     fhir:Quantity.code [ fhir:value "d" ]
  ];
  fhir:MedicationDispense.whenPrepared [ fhir:value "2015-01-15T10:20:00Z"^^xsd:dateTime];
  fhir:MedicationDispense.dosageInstruction [
     fhir:index 0;
     fhir:MedicationDispense.dosageInstruction.text [ fhir:value "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk" ];
     fhir:MedicationDispense.dosageInstruction.additionalInstructions [
       fhir:index 0;
       fhir:CodeableConcept.text [ fhir:value "Rapidly increase dose until tolerated" ]
     ], [
       fhir:index 1;
       fhir:CodeableConcept.text [ fhir:value "Administer on alternate days" ]
     ];
     fhir:MedicationDispense.dosageInstruction.timing [
       fhir:Timing.repeat [
         fhir:Timing.repeat.duration [ fhir:value "12"^^xsd:decimal ];
         fhir:Timing.repeat.durationUnit [ fhir:value "wk" ];
         fhir:Timing.repeat.frequency [ fhir:value "3"^^xsd:int ];
         fhir:Timing.repeat.period [ fhir:value "1"^^xsd:decimal ];
         fhir:Timing.repeat.periodUnit [ fhir:value "wk" ]
       ]
     ];
     fhir:MedicationDispense.dosageInstruction.route [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:concept sct:47625008;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "47625008" ];
         fhir:Coding.display [ fhir:value "Intravenous route (qualifier value)" ]
       ]
     ];
     fhir:MedicationDispense.dosageInstruction.method [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:concept sct:422145002;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "422145002" ];
         fhir:Coding.display [ fhir:value "Inject - dosing instruction imperative (qualifier value)" ]
       ]
     ];
     fhir:MedicationDispense.dosageInstruction.doseQuantity [
       fhir:Quantity.value [ fhir:value "3"^^xsd:decimal ];
       fhir:Quantity.unit [ fhir:value "mg" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "mg" ]
     ]
  ], [
     fhir:index 1;
     fhir:MedicationDispense.dosageInstruction.text [ fhir:value "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk" ];
     fhir:MedicationDispense.dosageInstruction.additionalInstructions [
       fhir:index 0;
       fhir:CodeableConcept.text [ fhir:value "Rapidly increase dose until tolerated" ]
     ], [
       fhir:index 1;
       fhir:CodeableConcept.text [ fhir:value "Administer on alternate days" ]
     ];
     fhir:MedicationDispense.dosageInstruction.timing [
       fhir:Timing.repeat [
         fhir:Timing.repeat.duration [ fhir:value "12"^^xsd:decimal ];
         fhir:Timing.repeat.durationUnit [ fhir:value "wk" ];
         fhir:Timing.repeat.frequency [ fhir:value "3"^^xsd:int ];
         fhir:Timing.repeat.period [ fhir:value "1"^^xsd:decimal ];
         fhir:Timing.repeat.periodUnit [ fhir:value "wk" ]
       ]
     ];
     fhir:MedicationDispense.dosageInstruction.route [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:concept sct:47625008;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "47625008" ];
         fhir:Coding.display [ fhir:value "Intravenous route (qualifier value)" ]
       ]
     ];
     fhir:MedicationDispense.dosageInstruction.method [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:concept sct:422145002;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "422145002" ];
         fhir:Coding.display [ fhir:value "Inject - dosing instruction imperative (qualifier value)" ]
       ]
     ];
     fhir:MedicationDispense.dosageInstruction.doseQuantity [
       fhir:Quantity.value [ fhir:value "10"^^xsd:decimal ];
       fhir:Quantity.unit [ fhir:value "mg" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "mg" ]
     ]
  ], [
     fhir:index 2;
     fhir:MedicationDispense.dosageInstruction.text [ fhir:value "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk" ];
     fhir:MedicationDispense.dosageInstruction.additionalInstructions [
       fhir:index 0;
       fhir:CodeableConcept.text [ fhir:value "Rapidly increase dose until tolerated" ]
     ], [
       fhir:index 1;
       fhir:CodeableConcept.text [ fhir:value "Administer on alternate days" ]
     ];
     fhir:MedicationDispense.dosageInstruction.timing [
       fhir:Timing.repeat [
         fhir:Timing.repeat.duration [ fhir:value "12"^^xsd:decimal ];
         fhir:Timing.repeat.durationUnit [ fhir:value "wk" ];
         fhir:Timing.repeat.frequency [ fhir:value "3"^^xsd:int ];
         fhir:Timing.repeat.period [ fhir:value "1"^^xsd:decimal ];
         fhir:Timing.repeat.periodUnit [ fhir:value "wk" ]
       ]
     ];
     fhir:MedicationDispense.dosageInstruction.route [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:concept sct:47625008;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "47625008" ];
         fhir:Coding.display [ fhir:value "Intravenous route (qualifier value)" ]
       ]
     ];
     fhir:MedicationDispense.dosageInstruction.method [
       fhir:CodeableConcept.coding [
         fhir:index 0;
         fhir:concept sct:422145002;
         fhir:Coding.system [ fhir:value "http://snomed.info/sct" ];
         fhir:Coding.code [ fhir:value "422145002" ];
         fhir:Coding.display [ fhir:value "Inject - dosing instruction imperative (qualifier value)" ]
       ]
     ];
     fhir:MedicationDispense.dosageInstruction.doseQuantity [
       fhir:Quantity.value [ fhir:value "30"^^xsd:decimal ];
       fhir:Quantity.unit [ fhir:value "mg" ];
       fhir:Quantity.system [ fhir:value "http://unitsofmeasure.org" ];
       fhir:Quantity.code [ fhir:value "mg" ]
     ]
  ] .

<http://hl7.org/fhir/Patient/pat1> a fhir:Patient .

<http://hl7.org/fhir/Practitioner/f006> a fhir:Practitioner .

<http://hl7.org/fhir/MedicationOrder/medrx0317> a fhir:MedicationOrder .

# -------------------------------------------------------------------------------------
Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.