DSTU2 QA Preview

This page is part of the FHIR Specification (v1.0.0: DSTU 2 Ballot 3). The current version which supercedes this version is 5.0.0. For a full list of available versions, see the Directory of published versions . Page versions: R5 R4B R4 R3 R2

Substance.profile.xml

Raw XML (canonical form)

StructureDefinition for substance

Raw XML

<StructureDefinition xmlns="http://hl7.org/fhir">
  <id value="Substance"/>
  <meta>
    <lastUpdated value="2015-09-01T14:38:48.206+10:00"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
      <table border="0" cellpadding="0" cellspacing="0" style="border: 0px; font-size: 11px; font-family: verdana; vertical-align: top;">
        <tr style="border: 1px #F0F0F0 solid; font-size: 11px; font-family: verdana; vertical-align: top;">
          <th class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="formats.html#table" title="The logical name of the element">Name</a>
          </th>
          <th class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="formats.html#table" title="Information about the use of the element">Flags</a>
          </th>
          <th class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="formats.html#table" title="Minimum and Maximum # of times the the element can appear in the instance">Card.</a>
          </th>
          <th class="heirarchy" style="width: 100px">
            <a href="formats.html#table" title="Reference to the type of the element">Type</a>
          </th>
          <th class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="formats.html#table" title="Additional information about the element">Description &amp; Constraints</a>
            <span style="float: right">
              <a href="formats.html#table" title="Legend for this format">
                <img alt="doco" src="help16.png" style="background-color: inherit"/>
              </a>
            </span>
          </th>
        </tr>
        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5
          CYII=)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABGdBTUEAAK/INwWK6QAAABl0RVh0U
            29mdHdhcmUAQWRvYmUgSW1hZ2VSZWFkeXHJZTwAAAJBSURBVDjLhdKxa5NBGMfx713yvkmbJnaoFiSF4mJTh06Kg4OgiyCCRXCof4
            YIdXdxFhQVHPo3OFSoUx0FySQttaVKYq2NbdO8ed/L3fM4JG3tYPvAcfBw9+HHPWdUlf/V0tLSqKo+EpEHInJFRIohhDUR+RBCeDM
            7O7ua55QSkRfVanVufHyckZERrLV0Op2Zra2tmXq9fg+YsmcAdyYnJykUCke9OI6ZmJgghHAZ4KwE3ntPs9mkVCohIjQaDWq1GiEE
            AM5KoHEcY62lVCrRarUoFotUKpUjIL/y/uqXYmV62ph/LSVrr30P4bEFcM4B0Ov1jk547/uAUTs1ceNdZIwB7V/GGHz6+9LXxY96e
            DiEgHMOY8xJAK8p4grZz5cElwNbwZgyxYu3EFM01lriOCZJEqIoIooiALIsGwA9Y1UcwcWoKNLdpLu9zvbnBWqNBhuvn5EDUmB0EH
            /1E2TZw5U+YLQovkun+Ytsaw1xCbnCOap334LC7s4Oe/ttvA+ICLmhMXRxDufczUECS37oAuevPwUEVFFp4/eXkXSdYc2IopSepnj
            tUh5/wg9gfn6+OQBUNaRIUkfDHhraSLoBKqikIF3yHJDLHaAkFOLciVHnyVAVj/S2Ub/XRyQD9aAZKgkaOohvo6ENgykcA07VEFDf
            Qv1uf4W9Y8y30bCPhg4qKZJtMnjTPqBO/vhkZ7h3EJeRslWNQMqgY2jIAIfa/m5sIKSpqpPsGEiz599e3b+GchtD+bSvjQJm2SG6c
            Nj6C+QmaxAek5tyAAAAAElFTkSuQmCC" style="background-color: white; background-color: inherit" title="Resource"/> 
            <span title="Substance : A homogeneous material with a definite composition.">Substance</span>
            <a name="Substance"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px"/>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px"/>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="domainresource.html">DomainResource</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">A homogeneous material with a definite composition</td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5
          CYII=)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav
            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,R0lGODlhEAAQAOZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQk
            ad4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRP
            z58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPv
            szv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866O
            UPvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6i
            f3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///////yH5BAEAAH8ALAAAAAAQABAAAAfNgH+Cg36FfoOIhH4JBxBghYl/hQ
            kNAV0IVT5GkJKLCwtQaSsSdx9aR26Gcwt2IkQaNRI6dBERIzCFDSgWSW8WCDkbBnoOQ3uFARc/JQJfCAZlT0x4ZFyFBxdNQT9ZCBN
            WKQoKUQ+FEDgcdTIAV14YDmg2CgSFA0hmQC5TLE4VRTdrKJAoxOeFCzZSwsw4U6BCizwUQhQyEaAPiAwCVNCY0FCNnA6GPAwYoETI
            FgY9loiRA4dToTYnsOxg8CBGHE6ICvEYQ4AKzkidfgoKBAA7" style="background-color: white; background-color: inherit" title="Data Type"/> 
            <span title="Substance.identifier : Unique identifier for the substance.">identifier</span>
            <a name="Substance.identifier"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">0..*</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Identifier">Identifier</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">Unique identifier</td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5
          CYII=)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav
            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,R0lGODlhEAAQAOZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQk
            ad4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRP
            z58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPv
            szv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866O
            UPvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6i
            f3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///////yH5BAEAAH8ALAAAAAAQABAAAAfNgH+Cg36FfoOIhH4JBxBghYl/hQ
            kNAV0IVT5GkJKLCwtQaSsSdx9aR26Gcwt2IkQaNRI6dBERIzCFDSgWSW8WCDkbBnoOQ3uFARc/JQJfCAZlT0x4ZFyFBxdNQT9ZCBN
            WKQoKUQ+FEDgcdTIAV14YDmg2CgSFA0hmQC5TLE4VRTdrKJAoxOeFCzZSwsw4U6BCizwUQhQyEaAPiAwCVNCY0FCNnA6GPAwYoETI
            FgY9loiRA4dToTYnsOxg8CBGHE6ICvEYQ4AKzkidfgoKBAA7" style="background-color: white; background-color: inherit" title="Data Type"/> 
            <span title="Substance.category : A code that classifies the the general type of substance.  This is
             used  for searching, sorting and display purposes.">category</span>
            <a name="Substance.category"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">0..*</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">What class/type of substance this is
            <br/>
            <a href="valueset-substance-category.html" title="Category or classification of substance">Substance Category Codes</a> (
            <a href="terminologies.html#extensible" title="To be conformant, instances of this element SHALL include a code from the specified value
             set if any of the codes within the value set can apply to the concept being communicated.
              If the valueset does not cover the concept (based on human review), alternate codings
             (or, data type allowing, text) may be included instead.">Extensible</a>)
          </td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5
          CYII=)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav
            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,R0lGODlhEAAQAOZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQk
            ad4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRP
            z58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPv
            szv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866O
            UPvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6i
            f3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///////yH5BAEAAH8ALAAAAAAQABAAAAfNgH+Cg36FfoOIhH4JBxBghYl/hQ
            kNAV0IVT5GkJKLCwtQaSsSdx9aR26Gcwt2IkQaNRI6dBERIzCFDSgWSW8WCDkbBnoOQ3uFARc/JQJfCAZlT0x4ZFyFBxdNQT9ZCBN
            WKQoKUQ+FEDgcdTIAV14YDmg2CgSFA0hmQC5TLE4VRTdrKJAoxOeFCzZSwsw4U6BCizwUQhQyEaAPiAwCVNCY0FCNnA6GPAwYoETI
            FgY9loiRA4dToTYnsOxg8CBGHE6ICvEYQ4AKzkidfgoKBAA7" style="background-color: white; background-color: inherit" title="Data Type"/> 
            <span title="Substance.code : A code (or set of codes) that identify this substance.">code</span>
            <a name="Substance.code"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">1..1</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">What substance this is
            <br/>
            <a href="valueset-substance-code.html" title="Substance codes">Substance Code</a> (
            <a href="terminologies.html#example" title="Instances are not expected or even encouraged to draw from the specified value set.  The
             value set merely provides examples of the types of concepts intended to be included">Example</a>)
          </td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5
          CYII=)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav
            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIW
            XMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i
            8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" style="background-color: white; background-color: inherit" title="Primitive Data Type"/> 
            <span title="Substance.description : A description of the substance - its appearance, handling requirements,
             and other usage notes.">description</span>
            <a name="Substance.description"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">0..1</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="datatypes.html#string">string</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">Textual description of the substance, comments</td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5
          CYII=)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav
            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,R0lGODlhEAAQAMQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw
            /npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///////yH5BAEAAB8ALAAAAAAQABAAAAV24CeOZG
            mepqeqqOgxjBZFa+19r4ftWQUAgqDgltthMshMIJAZ4jYDHsBARSAmFOJvq+g6HIdEFgcYmBWNxoNAsDjGHgBnmV5bCoUDHLBIq9s
            FEhIdcAYJdYASFRUQhQkLCwkOFwcdEBAXhVabE52ecDahKy0oIQA7" style="background-color: white; background-color: inherit" title="Element"/> 
            <span title="Substance.instance : Substance may be used to describe a kind of substance, or a specific
             package/container of the substance: an instance.">instance</span>
            <a name="Substance.instance"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">0..*</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="backboneelement.html">BackboneElement</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">If this describes a specific package/container of the substance</td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkS
          uQmCC)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwA
            v+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav
            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,R0lGODlhEAAQAOZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQk
            ad4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRP
            z58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPv
            szv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866O
            UPvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6i
            f3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///////yH5BAEAAH8ALAAAAAAQABAAAAfNgH+Cg36FfoOIhH4JBxBghYl/hQ
            kNAV0IVT5GkJKLCwtQaSsSdx9aR26Gcwt2IkQaNRI6dBERIzCFDSgWSW8WCDkbBnoOQ3uFARc/JQJfCAZlT0x4ZFyFBxdNQT9ZCBN
            WKQoKUQ+FEDgcdTIAV14YDmg2CgSFA0hmQC5TLE4VRTdrKJAoxOeFCzZSwsw4U6BCizwUQhQyEaAPiAwCVNCY0FCNnA6GPAwYoETI
            FgY9loiRA4dToTYnsOxg8CBGHE6ICvEYQ4AKzkidfgoKBAA7" style="background-color: white; background-color: inherit" title="Data Type"/> 
            <span title="Substance.instance.identifier : Identifier associated with the package/container (usually
             a label affixed directly).">identifier</span>
            <a name="Substance.instance.identifier"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">0..1</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Identifier">Identifier</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">Identifier of the package/container</td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkS
          uQmCC)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwA
            v+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav
            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIW
            XMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i
            8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" style="background-color: white; background-color: inherit" title="Primitive Data Type"/> 
            <span title="Substance.instance.expiry : When the substance is no longer valid to use. For some substances,
             a single arbitrary date is used for expiry.">expiry</span>
            <a name="Substance.instance.expiry"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">0..1</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="datatypes.html#dateTime">dateTime</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">When no longer valid to use</td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5
          CYII=)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwA
            v+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUO
            L+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,R0lGODlhEAAQAOZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQk
            ad4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRP
            z58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPv
            szv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866O
            UPvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6i
            f3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///////yH5BAEAAH8ALAAAAAAQABAAAAfNgH+Cg36FfoOIhH4JBxBghYl/hQ
            kNAV0IVT5GkJKLCwtQaSsSdx9aR26Gcwt2IkQaNRI6dBERIzCFDSgWSW8WCDkbBnoOQ3uFARc/JQJfCAZlT0x4ZFyFBxdNQT9ZCBN
            WKQoKUQ+FEDgcdTIAV14YDmg2CgSFA0hmQC5TLE4VRTdrKJAoxOeFCzZSwsw4U6BCizwUQhQyEaAPiAwCVNCY0FCNnA6GPAwYoETI
            FgY9loiRA4dToTYnsOxg8CBGHE6ICvEYQ4AKzkidfgoKBAA7" style="background-color: white; background-color: inherit" title="Data Type"/> 
            <span title="Substance.instance.quantity : The amount of the substance.">quantity</span>
            <a name="Substance.instance.quantity"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">0..1</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="datatypes.html#SimpleQuantity">SimpleQuantity</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">Amount of substance in the package</td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAI0lEQVR42u3QIQEAAAACIL/6/4MvTAQOkLYBAAB4kAAAANwMad9AqkRjgNAAAAAASUVORK5CYII=)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUO
            L+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,R0lGODlhEAAQAMQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw
            /npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///////yH5BAEAAB8ALAAAAAAQABAAAAV24CeOZG
            mepqeqqOgxjBZFa+19r4ftWQUAgqDgltthMshMIJAZ4jYDHsBARSAmFOJvq+g6HIdEFgcYmBWNxoNAsDjGHgBnmV5bCoUDHLBIq9s
            FEhIdcAYJdYASFRUQhQkLCwkOFwcdEBAXhVabE52ecDahKy0oIQA7" style="background-color: white; background-color: inherit" title="Element"/> 
            <span title="Substance.ingredient : A substance can be composed of other substances.">ingredient</span>
            <a name="Substance.ingredient"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">0..*</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="backboneelement.html">BackboneElement</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">Composition information about the substance</td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAALElEQVR42u3QwQkAMAwDsezq/WdIO4XJQwa9DTdJpulv258AAMANIgAAADUPYAVAgAJ//usAAAAASUVORK5CYII
          =)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiY
            FCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav
            7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,R0lGODlhEAAQAOZ/APrkusOiYvvfqbiXWaV2G+jGhdq1b8GgYf3v1frw3vTUlsWkZNewbcSjY/DQk
            ad4Hb6dXv3u0f3v1ObEgfPTlerJiP3w1v79+e7OkPrfrfnjuNOtZPrpydaxa+/YrvvdpP779ZxvFPvnwKKBQaFyF/369M2vdaqHRP
            z58/HNh/vowufFhfroxO3OkPrluv779tK0e6JzGProwvrow9m4eOnIifPTlPDPkP78+Naxaf3v0/zowfXRi+bFhLWUVv379/rnwPv
            szv3rye3LiPvnv+3MjPDasKiIS/789/3x2f747eXDg+7Mifvu0tu7f+/QkfDTnPXWmPrjsvrjtPbPgrqZW+/QlPz48K2EMv36866O
            UPvowat8Ivvgq/Pbrvzgq/PguvrgrqN0Gda2evfYm9+7d/rpw9q6e/LSku/Rl/XVl/LSlfrkt+zVqe7Wqv3x1/bNffbOf59wFdS6i
            f3u0vrqyP3owPvepfXQivDQkO/PkKh9K7STVf779P///////yH5BAEAAH8ALAAAAAAQABAAAAfNgH+Cg36FfoOIhH4JBxBghYl/hQ
            kNAV0IVT5GkJKLCwtQaSsSdx9aR26Gcwt2IkQaNRI6dBERIzCFDSgWSW8WCDkbBnoOQ3uFARc/JQJfCAZlT0x4ZFyFBxdNQT9ZCBN
            WKQoKUQ+FEDgcdTIAV14YDmg2CgSFA0hmQC5TLE4VRTdrKJAoxOeFCzZSwsw4U6BCizwUQhQyEaAPiAwCVNCY0FCNnA6GPAwYoETI
            FgY9loiRA4dToTYnsOxg8CBGHE6ICvEYQ4AKzkidfgoKBAA7" style="background-color: white; background-color: inherit" title="Data Type"/> 
            <span title="Substance.ingredient.quantity : The amount of the ingredient in the substance - a concentration
             ratio.">quantity</span>
            <a name="Substance.ingredient.quantity"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">0..1</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="datatypes.html#Ratio">Ratio</a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">Optional amount (concentration)</td>
        </tr>

        <tr style="border: 0px; padding:0px; vertical-align: top; background-color: white;">
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px;
           white-space: nowrap; background-image: url(data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCA
          YAAACg/LjIAAAAI0lEQVR42u3QIQEAAAACIL/6/4MvTAQOkLYBAAB4kAAAANwMad9AqkRjgNAAAAAASUVORK5CYII=)">
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAw
            NdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzIZgEiYEgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAIElEQVQ4y2P8//8/AyWAiY
            FCMGrAqAGjBowaMGoAAgAALL0DKYQ0DPIAAAAASUVORK5CYII=" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB
            3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUO
            L+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC" style="background-color: inherit"/>
            <img alt="." class="heirarchy" src="data: image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxj
            wv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjE
            EOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQ
            KlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC" style="background-color: white; background-color: inherit" title="Reference to another Resource"/> 
            <span title="Substance.ingredient.substance : Another substance that is a component of this substance.">substance</span>
            <a name="Substance.ingredient.substance"> </a>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <span title="This element is included in summaries">Σ</span>
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">1..1</td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">
            <a href="references.html">Reference</a>(
            <a href="substance.html">Substance</a>)
          </td>
          <td class="heirarchy" style="vertical-align: top; text-align : left; background-color: white; padding:0px 4px 0px 4px">A component of the substance</td>
        </tr>

        <tr>
          <td class="heirarchy" colspan="5">
            <br/>
            <a href="formats.html#table" title="Legend for this format">
              <img alt="doco" src="help16.png" style="background-color: inherit"/> Documentation for this format
            </a>
          </td>
        </tr>
      </table>
    </div>
  </text>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">
    <valueInteger value="0"/>
  </extension>
  <url value="http://hl7.org/fhir/StructureDefinition/Substance"/>
  <name value="Substance"/>
  <status value="draft"/>
  <publisher value="Health Level Seven International (Orders and Observations)"/>
  <contact>
    <telecom>
      <system value="other"/>
      <value value="http://hl7.org/fhir"/>
    </telecom>
  </contact>
  <contact>
    <telecom>
      <system value="other"/>
      <value value="http://www.hl7.org/Special/committees/orders/index.cfm"/>
    </telecom>
  </contact>
  <date value="2015-09-01T14:38:48+10:00"/>
  <description value="Base StructureDefinition for Substance Resource"/>
  <mapping>
    <identity value="orim"/>
    <uri value="http://hl7.org/orim"/>
    <name value="Ontological RIM Mapping"/>
  </mapping>
  <mapping>
    <identity value="rim"/>
    <uri value="http://hl7.org/v3"/>
    <name value="RIM"/>
  </mapping>
  <mapping>
    <identity value="w5"/>
    <uri value="http://hl7.org/fhir/w5"/>
    <name value="W5 Mapping"/>
  </mapping>
  <kind value="resource"/>
  <abstract value="false"/>
  <base value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>
  <snapshot>
    <element>
      <path value="Substance"/>
      <short value="A homogeneous material with a definite composition"/>
      <definition value="A homogeneous material with a definite composition."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="DomainResource"/>
      </type>
      <mapping>
        <identity value="orim"/>
        <map value="fhir:Substance rdfs:subClassOf   rim:Entity, [      a owl:Restriction;     owl:onProperty
          rim:Act.classCode;     owl:allValuesFrom  cs:EntityClass\#MAT   ]."/>
      </mapping>
      <mapping>
        <identity value="rim"/>
        <map value="Material"/>
      </mapping>
      <mapping>
        <identity value="w5"/>
        <map value="administrative.entity"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.id"/>
      <short value="Logical id of this artifact"/>
      <definition value="The logical id of the resource, as used in the url for the resource. Once assigned, this
       value never changes."/>
      <comments value="The only time that a resource does not have an id is when it is being submitted to the
       server using a create operation. Bundles always have an id, though it is usually a generated
       UUID."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="id"/>
      </type>
      <isSummary value="true"/>
    </element>
    <element>
      <path value="Substance.meta"/>
      <short value="Metadata about the resource"/>
      <definition value="The metadata about the resource. This is content that is maintained by the infrastructure.
       Changes to the content may not always be associated with version changes to the resource."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Meta"/>
      </type>
      <isSummary value="true"/>
    </element>
    <element>
      <path value="Substance.implicitRules"/>
      <short value="A set of rules under which this content was created"/>
      <definition value="A reference to a set of rules that were followed when the resource was constructed, and
       which must be understood when processing the content."/>
      <comments value="Asserting this rule set restricts the content to be only understood by a limited set of
       trading partners. This inherently limits the usefulness of the data in the long term.
       However the existing health eco-system is highly fractured, and not yet ready to define,
       collect, and exchange data in a generally computable sense. Wherever possible, implementers
       and/or specification writers should avoid using this element as much as possible."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="uri"/>
      </type>
      <isModifier value="true"/>
      <isSummary value="true"/>
    </element>
    <element>
      <path value="Substance.language"/>
      <short value="Language of the resource content"/>
      <definition value="The base language in which the resource is written."/>
      <comments value="Language is provided to support indexing and accessibility (typically, services such as
       text to speech use the language tag). The html language tag in the narrative applies 
       to the narrative. The language tag on the resource may be used to specify the language
       of other presentations generated from the data in the resource  Not all the content has
       to be in the base language. The Resource.language should not be assumed to apply to the
       narrative automatically. If a language is specified, it should it also be specified on
       the div element in the html (see rules in HTML5 for information about the relationship
       between xml:lang and the html lang attribute)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="code"/>
      </type>
      <binding>
        <strength value="required"/>
        <description value="A human language"/>
        <valueSetUri value="http://tools.ietf.org/html/bcp47"/>
      </binding>
    </element>
    <element>
      <path value="Substance.text"/>
      <short value="Text summary of the resource, for human interpretation"/>
      <definition value="A human-readable narrative that contains a summary of the resource, and may be used to
       represent the content of the resource to a human. The narrative need not encode all the
       structured data, but is required to contain sufficient detail to make it &quot;clinically
       safe&quot; for a human to just read the narrative. Resource definitions may define what
       content should be represented in the narrative to ensure clinical safety."/>
      <comments value="Contained resources do not have narrative. Resources that are not contained SHOULD have
       a narrative."/>
      <alias value="narrative"/>
      <alias value="html"/>
      <alias value="xhtml"/>
      <alias value="display"/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Narrative"/>
      </type>
      <condition value="dom-1"/>
      <mapping>
        <identity value="rim"/>
        <map value="Act.text?"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.contained"/>
      <short value="Contained, inline Resources"/>
      <definition value="These resources do not have an independent existence apart from the resource that contains
       them - they cannot be identified independently, and nor can they have their own independent
       transaction scope."/>
      <comments value="This should never be done when the content can be identified properly, as once identification
       is lost, it is extremely difficult (and context dependent) to restore it again."/>
      <alias value="inline resources"/>
      <alias value="anonymous resources"/>
      <alias value="contained resources"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Resource"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.extension"/>
      <short value="Additional Content defined by implementations"/>
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the resource. In order to make the use of extensions safe and manageable, there is
       a strict set of governance  applied to the definition and use of extensions. Though any
       implementer is allowed to define an extension, there is a set of requirements that SHALL
       be met as part of the definition of the extension."/>
      <comments value="There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Extension"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.modifierExtension"/>
      <short value="Extensions that cannot be ignored"/>
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the resource, and that modifies the understanding of the element that contains it.
       Usually modifier elements provide negation or qualification. In order to make the use
       of extensions safe and manageable, there is a strict set of governance applied to the
       definition and use of extensions. Though any implementer is allowed to define an extension,
       there is a set of requirements that SHALL be met as part of the definition of the extension.
       Applications processing a resource are required to check for modifier extensions."/>
      <comments value="There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Extension"/>
      </type>
      <isModifier value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.identifier"/>
      <short value="Unique identifier"/>
      <definition value="Unique identifier for the substance."/>
      <comments value="This identifier is associated with the kind of substance in contrast to the  Substance.instance.iden
      tifier which is associated with the package/container."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Identifier"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".id"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.category"/>
      <short value="What class/type of substance this is"/>
      <definition value="A code that classifies the the general type of substance.  This is used  for searching,
       sorting and display purposes."/>
      <comments value="The level of granularity is defined by the category concepts in the value set.   More
       fine-grained filtering can be performed using the metadata and/or terminology hierarchy
       in Substance.code."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="true"/>
      <binding>
        <strength value="extensible"/>
        <description value="Category or classification of substance"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/substance-category"/>
        </valueSetReference>
      </binding>
      <mapping>
        <identity value="rim"/>
        <map value=".code"/>
      </mapping>
      <mapping>
        <identity value="w5"/>
        <map value="class"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.code"/>
      <short value="What substance this is"/>
      <definition value="A code (or set of codes) that identify this substance."/>
      <comments value="This could be a reference to an externally defined code.  It could also be a locally assigned
       code (e.g. a formulary),  optionally with translations to the standard drug codes."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="true"/>
      <binding>
        <strength value="example"/>
        <description value="Substance codes"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/substance-code"/>
        </valueSetReference>
      </binding>
      <mapping>
        <identity value="orim"/>
        <map value="fhir:Substance.code rdfs:subPropertyOf rim:Entity.code"/>
      </mapping>
      <mapping>
        <identity value="rim"/>
        <map value=".code"/>
      </mapping>
      <mapping>
        <identity value="w5"/>
        <map value="what"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.description"/>
      <short value="Textual description of the substance, comments"/>
      <definition value="A description of the substance - its appearance, handling requirements, and other usage
       notes."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".player.desc"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance"/>
      <short value="If this describes a specific package/container of the substance"/>
      <definition value="Substance may be used to describe a kind of substance, or a specific package/container
       of the substance: an instance."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="BackboneElement"/>
      </type>
      <meaningWhenMissing value="If this element is not present, then the substance resource describes a kind of substance"/>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".player.determinerCode"/>
      </mapping>
      <mapping>
        <identity value="w5"/>
        <map value="class"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance.id"/>
      <representation value="xmlAttr"/>
      <short value="xml:id (or equivalent in JSON)"/>
      <definition value="unique id for the element within a resource (for internal references)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="id"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance.extension"/>
      <short value="Additional Content defined by implementations"/>
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. In order to make the use of extensions safe and manageable, there is a
       strict set of governance  applied to the definition and use of extensions. Though any
       implementer is allowed to define an extension, there is a set of requirements that SHALL
       be met as part of the definition of the extension."/>
      <comments value="There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Extension"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance.modifierExtension"/>
      <short value="Extensions that cannot be ignored"/>
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element, and that modifies the understanding of the element that contains it. Usually
       modifier elements provide negation or qualification. In order to make the use of extensions
       safe and manageable, there is a strict set of governance applied to the definition and
       use of extensions. Though any implementer is allowed to define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension. Applications
       processing a resource are required to check for modifier extensions."/>
      <comments value="There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <alias value="modifiers"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Extension"/>
      </type>
      <isModifier value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance.identifier"/>
      <short value="Identifier of the package/container"/>
      <definition value="Identifier associated with the package/container (usually a label affixed directly)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Identifier"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".id"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance.expiry"/>
      <short value="When no longer valid to use"/>
      <definition value="When the substance is no longer valid to use. For some substances, a single arbitrary
       date is used for expiry."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="dateTime"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".expiryTime"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance.quantity"/>
      <short value="Amount of substance in the package"/>
      <definition value="The amount of the substance."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Quantity"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".player.quantity"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.ingredient"/>
      <short value="Composition information about the substance"/>
      <definition value="A substance can be composed of other substances."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="BackboneElement"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".player.scopesRole[classCode=INGR]"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.ingredient.id"/>
      <representation value="xmlAttr"/>
      <short value="xml:id (or equivalent in JSON)"/>
      <definition value="unique id for the element within a resource (for internal references)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="id"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.ingredient.extension"/>
      <short value="Additional Content defined by implementations"/>
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element. In order to make the use of extensions safe and manageable, there is a
       strict set of governance  applied to the definition and use of extensions. Though any
       implementer is allowed to define an extension, there is a set of requirements that SHALL
       be met as part of the definition of the extension."/>
      <comments value="There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Extension"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.ingredient.modifierExtension"/>
      <short value="Extensions that cannot be ignored"/>
      <definition value="May be used to represent additional information that is not part of the basic definition
       of the element, and that modifies the understanding of the element that contains it. Usually
       modifier elements provide negation or qualification. In order to make the use of extensions
       safe and manageable, there is a strict set of governance applied to the definition and
       use of extensions. Though any implementer is allowed to define an extension, there is
       a set of requirements that SHALL be met as part of the definition of the extension. Applications
       processing a resource are required to check for modifier extensions."/>
      <comments value="There can be no stigma associated with the use of extensions by any application, project,
       or standard - regardless of the institution or jurisdiction that uses or defines the extensions.
        The use of extensions is what allows the FHIR specification to retain a core level of
       simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <alias value="modifiers"/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Extension"/>
      </type>
      <isModifier value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.ingredient.quantity"/>
      <short value="Optional amount (concentration)"/>
      <definition value="The amount of the ingredient in the substance - a concentration ratio."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Ratio"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".quantity"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.ingredient.substance"/>
      <short value="A component of the substance"/>
      <definition value="Another substance that is a component of this substance."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Substance"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".player"/>
      </mapping>
    </element>
  </snapshot>
  <differential>
    <element>
      <path value="Substance"/>
      <short value="A homogeneous material with a definite composition"/>
      <definition value="A homogeneous material with a definite composition."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="DomainResource"/>
      </type>
      <mapping>
        <identity value="orim"/>
        <map value="fhir:Substance rdfs:subClassOf   rim:Entity, [      a owl:Restriction;     owl:onProperty
          rim:Act.classCode;     owl:allValuesFrom  cs:EntityClass\#MAT   ]."/>
      </mapping>
      <mapping>
        <identity value="rim"/>
        <map value="Material"/>
      </mapping>
      <mapping>
        <identity value="w5"/>
        <map value="administrative.entity"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.identifier"/>
      <short value="Unique identifier"/>
      <definition value="Unique identifier for the substance."/>
      <comments value="This identifier is associated with the kind of substance in contrast to the  Substance.instance.iden
      tifier which is associated with the package/container."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Identifier"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".id"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.category"/>
      <short value="What class/type of substance this is"/>
      <definition value="A code that classifies the the general type of substance.  This is used  for searching,
       sorting and display purposes."/>
      <comments value="The level of granularity is defined by the category concepts in the value set.   More
       fine-grained filtering can be performed using the metadata and/or terminology hierarchy
       in Substance.code."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="true"/>
      <binding>
        <strength value="extensible"/>
        <description value="Category or classification of substance"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/substance-category"/>
        </valueSetReference>
      </binding>
      <mapping>
        <identity value="rim"/>
        <map value=".code"/>
      </mapping>
      <mapping>
        <identity value="w5"/>
        <map value="class"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.code"/>
      <short value="What substance this is"/>
      <definition value="A code (or set of codes) that identify this substance."/>
      <comments value="This could be a reference to an externally defined code.  It could also be a locally assigned
       code (e.g. a formulary),  optionally with translations to the standard drug codes."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="true"/>
      <binding>
        <strength value="example"/>
        <description value="Substance codes"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/substance-code"/>
        </valueSetReference>
      </binding>
      <mapping>
        <identity value="orim"/>
        <map value="fhir:Substance.code rdfs:subPropertyOf rim:Entity.code"/>
      </mapping>
      <mapping>
        <identity value="rim"/>
        <map value=".code"/>
      </mapping>
      <mapping>
        <identity value="w5"/>
        <map value="what"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.description"/>
      <short value="Textual description of the substance, comments"/>
      <definition value="A description of the substance - its appearance, handling requirements, and other usage
       notes."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".player.desc"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance"/>
      <short value="If this describes a specific package/container of the substance"/>
      <definition value="Substance may be used to describe a kind of substance, or a specific package/container
       of the substance: an instance."/>
      <min value="0"/>
      <max value="*"/>
      <meaningWhenMissing value="If this element is not present, then the substance resource describes a kind of substance"/>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".player.determinerCode"/>
      </mapping>
      <mapping>
        <identity value="w5"/>
        <map value="class"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance.identifier"/>
      <short value="Identifier of the package/container"/>
      <definition value="Identifier associated with the package/container (usually a label affixed directly)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Identifier"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".id"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance.expiry"/>
      <short value="When no longer valid to use"/>
      <definition value="When the substance is no longer valid to use. For some substances, a single arbitrary
       date is used for expiry."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="dateTime"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".expiryTime"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.instance.quantity"/>
      <short value="Amount of substance in the package"/>
      <definition value="The amount of the substance."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Quantity"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/SimpleQuantity"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".player.quantity"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.ingredient"/>
      <short value="Composition information about the substance"/>
      <definition value="A substance can be composed of other substances."/>
      <min value="0"/>
      <max value="*"/>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".player.scopesRole[classCode=INGR]"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.ingredient.quantity"/>
      <short value="Optional amount (concentration)"/>
      <definition value="The amount of the ingredient in the substance - a concentration ratio."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Ratio"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".quantity"/>
      </mapping>
    </element>
    <element>
      <path value="Substance.ingredient.substance"/>
      <short value="A component of the substance"/>
      <definition value="Another substance that is a component of this substance."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <profile value="http://hl7.org/fhir/StructureDefinition/Substance"/>
      </type>
      <isSummary value="true"/>
      <mapping>
        <identity value="rim"/>
        <map value=".player"/>
      </mapping>
    </element>
  </differential>
</StructureDefinition>

Usage note: every effort has been made to ensure that the examples are correct and useful, but they are not a normative part of the specification.