<?xml version="1.0" encoding="UTF-8"?>

<ValueSet xmlns="http://hl7.org/fhir">
  <id value="nehta-nehta-response-to-neoadjuvant-therapy"/>
  <meta>
    <lastUpdated value="2015-12-03T08:57:31.744+10:00"/>
    <profile value="http://hl7.org/fhir/StructureDefinition/valueset-shareable-definition"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
      <h2>ResponseToNeoadjuvantTherapy</h2>
      <p>The response of the tumour to neoadjuvant treatment must be recorded.</p>
      <p>
        <b>Copyright Statement:</b> This value set includes content from SNOMED CT, which is copyright Â© 2002+ International         Health Terminology Standards Development Organisation (IHTSDO), and distributed by         agreement    between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this         agreement
      </p>
      <p>This value set has an inline code system http://hl7.org/fhir/nehta-response-to-neoadjuvant-therapy, which defines the following codes:</p>
      <table class="codes">
        <tr>
          <td>
            <b>Code</b>
          </td>
          <td>
            <b>Display</b>
          </td>
          <td>
            <b>Definition</b>
          </td>
        </tr>
        <tr>
          <td>no_prior_treatment
            <a name="no_prior_treatment"> </a>
          </td>
          <td>No prior treatment</td>
          <td>No prior treatment</td>
        </tr>
      </table>
      <p>In addition, this value set includes codes from other code systems:</p>
      <ul>
        <li>Include these codes as defined in http://snomed.info/sct
          <table>
            <tr>
              <td>
                <b>Code</b>
              </td>
              <td>
                <b>Display</b>
              </td>
            </tr>
            <tr>
              <td>444431007</td>
              <td>Grade 0 on a scale of 0 to 3 (qualifier value)</td>
              <td/>
            </tr>
            <tr>
              <td>444456001</td>
              <td>Grade 1 on a scale of 0 to 3 (qualifier value)</td>
              <td/>
            </tr>
            <tr>
              <td>444457005</td>
              <td>Grade 2 on a scale of 0 to 3 (qualifier value)</td>
              <td/>
            </tr>
            <tr>
              <td>444447009</td>
              <td>Grade 3 on a scale of 0 to 3 (qualifier value)</td>
              <td/>
            </tr>
          </table>
        </li>
      </ul>
    </div>
  </text>
  <extension url="http://hl7.org/fhir/StructureDefinition/valueset-oid">
    <valueUri value="urn:oid:2.16.840.1.113883.4.642.2.0"/>
  </extension>
<!--  DMc ?? SR says to make into a NEHTA oid  -->
<!-- <extension url="http://hl7.org/fhir/StructureDefinition/valueset-oid">
    <valueUri value="urn:oid:2.16.840.1.113883.3.88.12.80.67"/>   
    </extension> -->
  <url value="http://hl7.org/fhir/ValueSet/nehta-nehta-response-to-neoadjuvant-therapy"/>
  <version value="20150625"/>
  <name value="ResponseToNeoadjuvantTherapy"/>
  <status value="draft"/>
  <experimental value="true"/>
  <publisher value="HL7 (FHIR Project)"/>
  <contact>
    <telecom>
      <system value="other"/>
      <value value="http://hl7.org/fhir"/>
    </telecom>
    <telecom>
      <system value="email"/>
      <value value="fhir@lists.hl7.org"/>
    </telecom>
  </contact>
  <date value="2015-06-11T16:01:03+10:00"/>
  <description value="The response of the tumour to neoadjuvant treatment must be recorded."/>
  <copyright value="This value set includes content from SNOMED CT, which is copyright Â© 2002+ International         Health Terminology Standards Development Organisation (IHTSDO), and distributed by         agreement    between IHTSDO and HL7. Implementer use of SNOMED CT is not covered by this         agreement"/>
  <codeSystem>
  <!--  These result values are from  
            Ryan R, Gibbons D and Hyland JMP (2005). Pathological response following long-course neoadjuvant 
            chemoradiotherapy for locally advanced rectal cancer. Histopathology(47):141-146.   -->
  <!--  DMc ?? SR says to make into a NEHTA oid  -->
  <!-- <extension url="http://hl7.org/fhir/StructureDefinition/valueset-oid">
            <valueUri value="urn:oid:2.16.840.1.113883.3.88.12.80.67"/>   
        </extension> -->
    <system value="http://hl7.org/fhir/nehta-response-to-neoadjuvant-therapy"/>
    <version value="20150625"/>
    <caseSensitive value="true"/>
    <concept>
      <code value="no_prior_treatment"/>
      <display value="No prior treatment"/>
      <definition value="No prior treatment"/>
    </concept>
  <!-- <concept>
            <code value="grade_0_complete_response"/>
            <display value="Grade 0 (complete response) No viable cancer cells"/>
            <definition value="Grade 0 (complete response) No viable cancer cells"/>
        </concept>
        <concept>
            <code value="grade_1_moderate_response"/>
            <display value="Grade 1 (moderate response) Single cells or small groups of cancer cells"/>
            <definition value="Grade 1 (moderate response) Single cells or small groups of cancer cells"/>
        </concept>
        <concept>
            <code value="grade_2_minimal_response"/>
            <display value="Grade 2 (minimal response) Residual cancer outgrown by fibrosis"/>
            <definition value="Grade 2 (minimal response) Residual cancer outgrown by fibrosis"/>
        </concept>
        <concept>
            <code value="grade_3_poor_response"/>
            <display value="Grade 3 (poor response) Minimal or no tumour kill; extensive residual cancer."/>
            <definition value="Grade 3 (poor response) Minimal or no tumour kill; extensive residual cancer."/>
        </concept> -->
  </codeSystem>
  <compose>
    <include>
      <system value="http://snomed.info/sct"/>
      <concept>
        <code value="444431007"/>
        <display value="Grade 0 on a scale of 0 to 3 (qualifier value)"/>
      </concept>
      <concept>
        <code value="444456001"/>
        <display value="Grade 1 on a scale of 0 to 3 (qualifier value)"/>
      </concept>
      <concept>
        <code value="444457005"/>
        <display value="Grade 2 on a scale of 0 to 3 (qualifier value)"/>
      </concept>
      <concept>
        <code value="444447009"/>
        <display value="Grade 3 on a scale of 0 to 3 (qualifier value)"/>
      </concept>
    </include>
  </compose>
</ValueSet>